NOX enzymes and the biology of reactive oxygen

scientific article (publication date: March 2004)

NOX enzymes and the biology of reactive oxygen is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1038/NRI1312
P3181OpenCitations bibliographic resource ID1088765
P698PubMed publication ID15039755

P2093author name stringLambeth JD
P2860cites workCell transformation by the superoxide-generating oxidase Mox1Q22010372
Purification of a novel flavoprotein involved in the thyroid NADPH oxidase. Cloning of the porcine and human cdnasQ22010938
Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase familyQ22254073
Identification of renox, an NAD(P)H oxidase in kidneyQ22254385
Hydrogen peroxide mediates the cell growth and transformation caused by the mitogenic oxidase Nox1Q24291189
A Ca(2+)-activated NADPH oxidase in testis, spleen, and lymph nodesQ24291514
Tyrosine cross-linking of extracellular matrix is catalyzed by Duox, a multidomain oxidase/peroxidase with homology to the phagocyte oxidase subunit gp91phoxQ24291589
Reactive oxygen generated by Nox1 triggers the angiogenic switchQ24292207
Killing activity of neutrophils is mediated through activation of proteases by K+ fluxQ24292504
Novel Human Homologues of p47 and p67 Participate in Activation of Superoxide-producing NADPH OxidasesQ24300616
The NAD(P)H oxidase homolog Nox4 modulates insulin-stimulated generation of H2O2 and plays an integral role in insulin signal transductionQ24607854
Phosphorylation of p47phox directs phox homology domain from SH3 domain toward phosphoinositides, leading to phagocyte NADPH oxidase activationQ24681540
Structure of the TPR domain of p67phox in complex with Rac.GTPQ27628646
Solution structure of the PX domain, a target of the SH3 domainQ27632043
Molecular basis of phosphorylation-induced activation of the NADPH oxidaseQ27641143
X-ray crystal structure of canine myeloperoxidase at 3 A resolutionQ27642075
Dual oxidases represent novel hydrogen peroxide sources supporting mucosal surface host defenseQ28181893
Homologs of gp91phox: cloning and tissue expression of Nox3, Nox4, and Nox5Q28190953
Inactivating mutations in the gene for thyroid oxidase 2 (THOX2) and congenital hypothyroidismQ28214074
The NADPH oxidase and chronic granulomatous diseaseQ28289081
Novel gp91(phox) homologues in vascular smooth muscle cells : nox1 mediates angiotensin II-induced superoxide formation and redox-sensitive signaling pathwaysQ28571066
NADPH oxidase is involved in prostaglandin F2alpha-induced hypertrophy of vascular smooth muscle cells: induction of NOX1 by PGF2alphaQ28580547
Two novel proteins activate superoxide generation by the NADPH oxidase NOX1Q28585409
Tetratricopeptide repeat (TPR) motifs of p67(phox) participate in interaction with the small GTPase Rac and activation of the phagocyte NADPH oxidaseQ28609613
Regulation of phagocyte oxygen radical production by the GTP-binding protein Rac 2Q28609631
Reversible inactivation of the tumor suppressor PTEN by H2O2Q29615204
Reversible oxidation and inactivation of protein tyrosine phosphatases in vivoQ29615579
The PX domains of p47phox and p40phox bind to lipid products of PI(3)KQ30016925
NOXO1, Regulation of Lipid Binding, Localization, and Activation of Nox1 by the Phox Homology (PX) DomainQ30164408
Proteins homologous to p47phox and p67phox support superoxide production by NAD(P)H oxidase 1 in colon epithelial cellsQ30164806
A novel superoxide-producing NAD(P)H oxidase in kidneyQ33921569
Evidence for antibody-catalyzed ozone formation in bacterial killing and inflammationQ33962509
Novel homologs of gp91phox.Q34069745
An NAD(P)H oxidase regulates growth and transcription in melanoma cellsQ34127326
NAD(P)H oxidase 1, a product of differentiated colon epithelial cells, can partially replace glycoprotein 91phox in the regulated production of superoxide by phagocytesQ34207369
Association of gp91phox homolog Nox1 with anchorage-independent growth and MAP kinase-activation of transformed human keratinocytes.Q34227862
Distinct subcellular localizations of Nox1 and Nox4 in vascular smooth muscle cellsQ34283019
Reversible inactivation of protein-tyrosine phosphatase 1B in A431 cells stimulated with epidermal growth factorQ34471453
The neutrophil NADPH oxidaseQ34497891
Modulation of p47 PHOX activity by site-specific phosphorylation: Akt-dependent activation of the NADPH oxidaseQ34982130
The superoxide-generating NADPH oxidase: structural aspects and activation mechanismQ35003216
Role of NADPH oxidases in the control of vascular gene expressionQ35572635
Pulsatile versus oscillatory shear stress regulates NADPH oxidase subunit expression: implication for native LDL oxidationQ35611252
Singlet oxygen production by biological systemsQ38203767
Regulation of the neutrophil respiratory burst oxidase. Identification of an activation domain in p67(phox).Q38336129
Type I Helicobacter pylori lipopolysaccharide stimulates toll-like receptor 4 and activates mitogen oxidase 1 in gastric pit cellsQ39521158
Superoxide and hydrogen peroxide in relation to mammalian cell proliferationQ40525865
Upregulation of the vascular NAD(P)H-oxidase isoforms Nox1 and Nox4 by the renin-angiotensin system in vitro and in vivoQ40765724
PU.1, interferon regulatory factor 1, and interferon consensus sequence-binding protein cooperate to increase gp91(phox) expressionQ41037531
Superoxide production and expression of NAD(P)H oxidases by transformed and primary human colonic epithelial cellsQ42113918
The p40phox and p47phox PX domains of NADPH oxidase target cell membranes via direct and indirect recruitment by phosphoinositides.Q43812779
Upregulation of Nox-based NAD(P)H oxidases in restenosis after carotid injuryQ43852782
Superoxide production and expression of nox family proteins in human atherosclerosisQ43933078
Immunology. Lethal weaponsQ43971313
The p47phox PX domain: two heads are better than one!Q44177583
Immunology. Catalytic antibody bridges innate and adaptive immunityQ44248382
A novel assay system implicates PtdIns(3,4)P(2), PtdIns(3)P, and PKC delta in intracellular production of reactive oxygen species by the NADPH oxidaseQ44283104
NOX5 NAD(P)H oxidase regulates growth and apoptosis in DU 145 prostate cancer cellsQ44397861
Hypochlorous acid generated by myeloperoxidase modifies adjacent tryptophan and glycine residues in the catalytic domain of matrix metalloproteinase-7 (matrilysin): an oxidative mechanism for restraining proteolytic activity during inflammationQ44448828
Guinea pig gastric mucosal cells produce abundant superoxide anion through an NADPH oxidase-like systemQ46371235
Lifespan extension and rescue of spongiform encephalopathy in superoxide dismutase 2 nullizygous mice treated with superoxide dismutase-catalase mimetics.Q46403225
Activation of the leukocyte NADPH oxidase by phorbol ester requires the phosphorylation of p47PHOX on serine 303 or 304.Q46874695
Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1Q59053220
Regulation of growth and apoptosis of cultured guinea pig gastric mucosal cells by mitogenic oxidase 1Q73230217
The p67(phox) activation domain regulates electron flow from NADPH to flavin in flavocytochrome b(558)Q78101657
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectoxygenQ629
nitrogen oxideQ424418
P304page(s)181-9
P577publication date2004-03-01
P1433published inNature Reviews ImmunologyQ43355
P1476titleNOX enzymes and the biology of reactive oxygen
P478volume4

Reverse relations

cites work (P2860)
Q58797324, a Gene Encoding a Putative Component of the RSC Chromatin Remodeling Complex, Is Involved in Hyphal Growth, Reactive Oxygen Species Accumulation, and Pathogenicity in
Q365938611-42 β-amyloid peptide requires PDK1/nPKC/Rac 1 pathway to induce neuronal death.
Q614453161-Octen-3-ol, a self-stimulating oxylipin messenger, can prime and induce defense of marine alga
Q5013670413 reasons why the brain is susceptible to oxidative stress.
Q499103382,5-Hexanedione induces dopaminergic neurodegeneration through integrin αMβ2/NADPH oxidase axis-mediated microglial activation.
Q363137302-Cys peroxiredoxin function in intracellular signal transduction: therapeutic implications
Q4209801420-HETE increases superoxide production and activates NAPDH oxidase in pulmonary artery endothelial cells.
Q420242805-aminoimidazole-4-carboxamide Riboside Induces Apoptosis Through AMP-activated Protein Kinase-independent and NADPH Oxidase-dependent Pathways
Q38989112A Critical Review of Methodologies to Detect Reactive Oxygen and Nitrogen Species Stimulated by NADPH Oxidase Enzymes: Implications in Pesticide Toxicity
Q39231516A Feed-Forward Mechanism Involving the NOX Complex and RyR-Mediated Ca2+ Release During Axonal Specification.
Q38663550A GalNAc/Gal-specific lectin from the sea mussel Crenomytilus grayanus modulates immune response in macrophages and in mice.
Q40762911A calcium-redox feedback loop controls human monocyte immune responses: The role of ORAI Ca2+ channels.
Q90125235A homologue of the fungal tetraspanin Pls1 is required for Epichloë festucae expressorium formation and establishment of a mutualistic interaction with Lolium perenne
Q36342127A metabolite of Danshen formulae attenuates cardiac fibrosis induced by isoprenaline, via a NOX2/ROS/p38 pathway
Q21144975A model for damage load and its implications for the evolution of bacterial aging
Q33660799A novel and specific NADPH oxidase-1 (Nox1) small-molecule inhibitor blocks the formation of functional invadopodia in human colon cancer cells
Q42695490A novel brain injury mechanism after intracerebral hemorrhage: the interaction between heme products and the immune system
Q24657774A novel host defense system of airways is defective in cystic fibrosis
Q35429351A novel mitochondrial membrane protein, Ohmm, limits fungal oxidative stress resistance and virulence in the insect fungal pathogen Beauveria bassiana
Q24677953A p67Phox-like regulator is recruited to control hyphal branching in a fungal-grass mutualistic symbiosis
Q33548893A palette of fluorescent probes with varying emission colors for imaging hydrogen peroxide signaling in living cells
Q42942079A possible mechanism for the apocynin-induced nitric oxide accumulation in plants
Q24339412A reactive oxygen species-mediated, self-perpetuating loop persistently activates platelet-derived growth factor receptor α
Q24296133A region C-terminal to the proline-rich core of p47phox regulates activation of the phagocyte NADPH oxidase by interacting with the C-terminal SH3 domain of p67phox
Q36183940A role of fluoride on free radical generation and oxidative stress in BV-2 microglia cells
Q91624186A thermodynamically-constrained mathematical model for the kinetics and regulation of NADPH oxidase 2 complex-mediated electron transfer and superoxide production
Q42496593A transverse tubule NADPH oxidase activity stimulates calcium release from isolated triads via ryanodine receptor type 1 S -glutathionylation.
Q33895641A two-photon fluorescent probe for ratiometric imaging of hydrogen peroxide in live tissue
Q24557443ACRATA: a novel electron transfer domain associated to apoptosis and cancer
Q33910919AIF suppresses chemical stress-induced apoptosis and maintains the transformed state of tumor cells
Q28568956ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages
Q38448103Accumulation of isolevuglandin-modified protein in normal and fibrotic lung
Q46264260Acetylsalicylic Acid Produces Different Effects on the Production of Active Oxygen Species by Activated Platelets in Different Inflammatory Diseases
Q38866879Actin filaments-A target for redox regulation
Q39337755Activated platelet chemiluminescence and presence of CD45+ platelets in patients with acute myocardial infarction.
Q28297425Activation and assembly of the NADPH oxidase: a structural perspective
Q40126147Activation and inactivation of the volume-sensitive taurine leak pathway in NIH3T3 fibroblasts and Ehrlich Lettre ascites cells
Q37446058Activation of AMPK enhances neutrophil chemotaxis and bacterial killing
Q27349131Activation of EGFR by small compounds through coupling the generation of hydrogen peroxide to stable dimerization of Cu/Zn SOD1.
Q28577965Activation of H2O2-induced VSOR Cl- currents in HTC cells require phospholipase Cgamma1 phosphorylation and Ca2+ mobilisation
Q41265386Activation of NAD(P)H oxidases by thromboxane A2 receptor uncouples endothelial nitric oxide synthase.
Q28584136Activation of NADPH oxidase and extracellular superoxide production in seizure-induced hippocampal damage
Q45072986Activation of NADPH oxidase is essential, but not sufficient, in controlling intracellular multiplication of Burkholderia pseudomallei in primary human monocytes
Q42447798Activation of dual oxidases Duox1 and Duox2: differential regulation mediated by camp-dependent protein kinase and protein kinase C-dependent phosphorylation
Q36952061Activation of microglia with zymosan promotes excitatory amino acid release via volume-regulated anion channels: the role of NADPH oxidases
Q24303790Activation of the superoxide-producing phagocyte NADPH oxidase requires co-operation between the tandem SH3 domains of p47phox in recognition of a polyproline type II helix and an adjacent alpha-helix of p22phox
Q92443515Activity Dependence of a Novel Lectin Family on Structure and Carbohydrate-Binding Properties
Q64084456Acute Effects of Heat-Not-Burn, Electronic Vaping, and Traditional Tobacco Combustion Cigarettes: The Sapienza University of Rome-Vascular Assessment of Proatherosclerotic Effects of Smoking ( SUR - VAPES ) 2 Randomized Trial
Q39930257Adiponectin Attenuates Angiotensin II-Induced Vascular Smooth Muscle Cell Remodeling through Nitric Oxide and the RhoA/ROCK Pathway
Q37330852Adipose-derived mesenchymal stem cells promote the survival of fat grafts via crosstalk between the Nrf2 and TLR4 pathways
Q42473055Advanced age protects microvascular endothelium from aberrant Ca(2+) influx and cell death induced by hydrogen peroxide
Q90192057Advanced oxidation protein products increase TNF-α and IL-1β expression in chondrocytes via NADPH oxidase 4 and accelerate cartilage degeneration in osteoarthritis progression
Q42829265Adverse effects of the classic antioxidant uric acid in adipocytes: NADPH oxidase-mediated oxidative/nitrosative stress
Q40205352Aeroallergens Induce Reactive Oxygen Species Production and DNA Damage and Dampen Antioxidant Responses in Bronchial Epithelial Cells
Q33348887Age-related alterations in oxidatively damaged proteins of mouse skeletal muscle mitochondrial electron transport chain complexes
Q36862034Aging mechanisms in bone
Q37566155Aldose reductase mediates endothelial cell dysfunction induced by high uric acid concentrations
Q34085559All-trans retinoic acid mediates DUOX2 expression and function in respiratory tract epithelium
Q34848818Alpha-tocopherol protects against oxidative stress in the fragile X knockout mouse: an experimental therapeutic approach for the Fmr1 deficiency
Q35562672Alsin and SOD1(G93A) proteins regulate endosomal reactive oxygen species production by glial cells and proinflammatory pathways responsible for neurotoxicity
Q49203551Alternative use of Bacillus subtilis spores: protection against environmental oxidative stress in human normal keratinocytes.
Q34537660Amorphous nanosilica induce endocytosis-dependent ROS generation and DNA damage in human keratinocytes.
Q37057861Amputation-induced reactive oxygen species are required for successful Xenopus tadpole tail regeneration
Q37040326An Endothelial Hsp70-TLR4 Axis Limits Nox3 Expression and Protects Against Oxidant Injury in Lungs
Q34515602An N-myristoylated globin with a redox-sensing function that regulates the defecation cycle in Caenorhabditis elegans
Q24673498An Ustilago maydis gene involved in H2O2 detoxification is required for virulence
Q28540312An anti-interleukin-2 receptor drug attenuates T- helper 1 lymphocytes-mediated inflammation in an acute model of endotoxin-induced uveitis
Q39095703An antioxidant nanozyme that uncovers the cytoprotective potential of vanadia nanowires
Q35133190An evolutionary analysis of antigen processing and presentation across different timescales reveals pervasive selection
Q41957450An improved superoxide-generating nanodevice for oxidative stress studies in cultured cells
Q39422960An unexpected friend - ROS in apoptosis-induced compensatory proliferation: Implications for regeneration and cancer
Q60682871Angiotensin II Triggers Peripheral Macrophage-to-Sensory Neuron Redox Crosstalk to Elicit Pain
Q37859447Angiotensin II and the vascular phenotype in hypertension
Q37166958Angiotensin II-induced production of mitochondrial reactive oxygen species: potential mechanisms and relevance for cardiovascular disease
Q36497289Annexin A1, formyl peptide receptor, and NOX1 orchestrate epithelial repair
Q92400021Antepenultimate residue at the C-terminus of NADPH oxidase RBOHD is critical for its function in the production of reactive oxygen species in Arabidopsis
Q39392738Antibody-induced nonapoptotic cell death in human lymphoma and leukemia cells is mediated through a novel reactive oxygen species-dependent pathway
Q28252753Antihypertensive effects and mechanisms of chlorogenic acids
Q88956461Antimicrobial actions of dual oxidases and lactoperoxidase
Q37258404Antioxidant therapy in multiple sclerosis.
Q38244092Antioxidative defense mechanisms controlled by Nrf2: state-of-the-art and clinical perspectives in neurodegenerative diseases
Q35011925Antitumor effects of OSU-2S, a nonimmunosuppressive analogue of FTY720, in hepatocellular carcinoma
Q36168673Apocynin Attenuates Cardiac Injury in Type 4 Cardiorenal Syndrome via Suppressing Cardiac Fibroblast Growth Factor-2 With Oxidative Stress Inhibition
Q36405651Apocynin and Diphenyleneiodonium Induce Oxidative Stress and Modulate PI3K/Akt and MAPK/Erk Activity in Mouse Embryonic Stem Cells.
Q42403010Apocynin improves outcome in experimental stroke with a narrow dose range
Q46088295Apocynin-induced nitric oxide production confers antioxidant protection in maize leaves
Q37079239Application of angiogenesis to clinical dermatology
Q40364164Aquaporin8 regulates cellular development and reactive oxygen species production, a critical component of virulence in Botrytis cinerea.
Q34138960Arachidonic acid induces direct interaction of the p67(phox)-Rac complex with the phagocyte oxidase Nox2, leading to superoxide production
Q44161216Aryl hydrocarbon receptor protects against bacterial infection by promoting macrophage survival and reactive oxygen species production
Q43072125Aspirin can stimulate luminol-enhanced chemiluminescence of activated platelets.
Q38921494Association between NADPH oxidase (NOX) and lung cancer: a systematic review and meta-analysis
Q37449928Atherogenic dyslipidemia and oxidative stress: a new look.
Q64911504Atractylenolide III Attenuates Muscle Wasting in Chronic Kidney Disease via the Oxidative Stress-Mediated PI3K/AKT/mTOR Pathway.
Q41917553Autophagy prevents autophagic cell death in Tetrahymena in response to oxidative stress
Q24307761Autophagy protein Rubicon mediates phagocytic NADPH oxidase activation in response to microbial infection or TLR stimulation
Q64243552Autophagy: Dual Response in the Development of Hepatocellular Carcinoma
Q38726500Bacillus amyloliquefaciens SC06 alleviates the oxidative stress of IPEC-1 via modulating Nrf2/Keap1 signaling pathway and decreasing ROS production
Q37379585Bacterial-modulated host immunity and stem cell activation for gut homeostasis
Q26998655Bang-bang model for regulation of local blood flow
Q34032319Barrett's esophagus: progression to adenocarcinoma and markers
Q45090799BcNoxD, a putative ER protein, is a new component of the NADPH oxidase complex in Botrytis cinerea
Q39871422Bcr-Abl-mediated redox regulation of the PI3K/AKT pathway
Q39714531Berberine inhibits NADPH oxidase mediated superoxide anion production in macrophages
Q27011356Beyond oxidative stress: an immunologist's guide to reactive oxygen species
Q92732863Bicarbonate is essential for protein-tyrosine phosphatase 1B (PTP1B) oxidation and cellular signaling through EGF-triggered phosphorylation cascades
Q34727374Bilirubin attenuates the renal tubular injury by inhibition of oxidative stress and apoptosis
Q46621289Bimodal role of NADPH oxidases in the regulation of biglycan-triggered IL-1β synthesis.
Q36376440Biological signaling by small inorganic molecules
Q54974180Bone Marrow-Derived Mononuclear Cell Therapy in Papain-Induced Experimental Pulmonary Emphysema.
Q46591953Bone marrow chimeras in the study of experimental stroke
Q42397400Bordetella bronchiseptica responses to physiological reactive nitrogen and oxygen stresses
Q35226300Boronate oxidation as a bioorthogonal reaction approach for studying the chemistry of hydrogen peroxide in living systems
Q33895637Boronate-based fluorescent probes: imaging hydrogen peroxide in living systems.
Q33711758C-jun inhibits mammary apoptosis in vivo
Q34340880C. elegans epidermal wounding induces a mitochondrial ROS burst that promotes wound repair
Q39052178C242T polymorphism of NADPH oxidase p22phox gene reduces the risk of coronary artery disease in a random sample of Egyptian population.
Q39797161CARD9 facilitates microbe-elicited production of reactive oxygen species by regulating the LyGDI-Rac1 complex
Q37449836CK2 is a novel negative regulator of NADPH oxidase and a neuroprotectant in mice after cerebral ischemia
Q38788608CXCR3.1 and CXCR3.2 Differentially Contribute to Macrophage Polarization in Teleost Fish
Q42708437Caffeic acid phenethyl ester inhibits diesel exhaust particle-induced inflammation of human middle ear epithelial cells via NOX4 inhibition
Q35245361Calcium and reactive oxygen species in acute pancreatitis: friend or foe?
Q48080421Calcium-dependent protein kinases regulate the production of reactive oxygen species by potato NADPH oxidase
Q33923188Calcium/calmodulin-dependent kinase II mediates the phosphorylation and activation of NADPH oxidase 5.
Q46953289Calpains promote neutrophil recruitment and bacterial clearance in an acute bacterial peritonitis model
Q37580432Cambogin exerts anti-proliferative and pro-apoptotic effects on breast adenocarcinoma through the induction of NADPH oxidase 1 and the alteration of mitochondrial morphology and dynamics
Q36444969Cancer-preventive anti-oxidants that attenuate free radical generation by inflammatory cells
Q42498522Cardioprotective effect of a hemoglobin-based oxygen carrier on cold ischemia/reperfusion injury
Q46966592Cathelicidin LL-37 induces the generation of reactive oxygen species and release of human alpha-defensins from neutrophils
Q24645333Ce-Duox1/BLI-3 generates reactive oxygen species as a protective innate immune mechanism in Caenorhabditis elegans
Q62570923Cell aging-induced methionine oxidation causes an autocrine to paracrine shift of the pheromone activity in the protozoan ciliate, Euplotes raikovi
Q36321683Cell signaling through protein kinase C oxidation and activation
Q37268365Cell-specific effects of Nox2 on the acute and chronic response to myocardial infarction.
Q88122160Cellular and Site-Specific Mitochondrial Characterization of Vital Human Amniotic Membrane
Q46898679Cellular respiration: the nexus of stress, condition, and ornamentation
Q37268120Cerebral vascular dysregulation in the ischemic brain
Q86804323Cerebrospinal fluid and plasma oxidative stress biomarkers in different clinical phenotypes of neuroinflammatory acute attacks. Conceptual accession: from fundamental to clinic
Q38722535Chaetocin reactivates the lytic replication of Epstein-Barr virus from latency via reactive oxygen species
Q28566624Changes in the subcellular distribution of NADPH oxidase subunit p47phox in dendrites of rat dorsomedial nucleus tractus solitarius neurons in response to chronic administration of hypertensive agents
Q42662658Characteristics of NADPH oxidase genes (Nox2, p22, p47, and p67) and Nox4 gene expressed in blood cells of juvenile Ciona intestinalis
Q37384931Characterization of NADPH oxidase 5 expression in human tumors and tumor cell lines with a novel mouse monoclonal antibody
Q38697307Characterization of potent and selective iodonium-class inhibitors of NADPH oxidases
Q46262615Chemical Probes for Redox Signaling and Oxidative Stress.
Q24633682Chemistry and biology of reactive oxygen species in signaling or stress responses
Q35222202Chemotherapy-induced weakness and fatigue in skeletal muscle: the role of oxidative stress
Q34502590Chronic granulomatous disease: why an inflammatory disease?
Q39192539Cinnamaldehyde ameliorates LPS-induced cardiac dysfunction via TLR4-NOX4 pathway: The regulation of autophagy and ROS production.
Q46318112Cisplatin-induced human peripheral blood mononuclear cells' oxidative stress and nephrotoxicity in head and neck cancer patients: the influence of hydrogen peroxide
Q89435460ClC-3 promotes angiotensin II-induced reactive oxygen species production in endothelial cells by facilitating Nox2 NADPH oxidase complex formation
Q43085735Class I phosphoinositide-3-kinases and SRC kinases play a nonredundant role in regulation of adhesion-independent and -dependent neutrophil reactive oxygen species generation
Q26865538Classification of H₂O₂as a neuromodulator that regulates striatal dopamine release on a subsecond time scale
Q28221768Close functional coupling between Ca2+ release-activated Ca2+ channels and reactive oxygen species production in murine macrophages
Q33267280Clues to neuro-degeneration in Niemann-Pick type C disease from global gene expression profiling
Q42846203Co-occurrence of tetraspanin and ROS generators: Conservation in protein cross-linking and other developmental processes
Q38609997Cognitive impairment in humanized APP×PS1 mice is linked to Aβ(1-42) and NOX activation.
Q35992729Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets
Q59791989Combination of chemotherapy and physical plasma elicits melanoma cell death via upregulation of SLC22A16
Q39053766Combined incubation of colon carcinoma cells with phorbol ester and mitochondrial uncoupling agents results in synergic elevated reactive oxygen species levels and increased γ-glutamyltransferase expression
Q24296438Commensal bacteria modulate cullin-dependent signaling via generation of reactive oxygen species
Q37441111Comparative mRNA and MicroRNA Profiling during Acute Myocardial Infarction Induced by Coronary Occlusion and Ablation Radio-Frequency Currents
Q37584499Comparative proteomic analysis of liver antioxidant mechanisms in Megalobrama amblycephala stimulated with dietary emodin
Q25257237Comparison of gene expression signatures of diamide, H2O2 and menadione exposed Aspergillus nidulans cultures--linking genome-wide transcriptional changes to cellular physiology
Q36155935Comparison of select innate immune mechanisms of fish and mammals
Q37322476Compartmentalization of redox signaling through NADPH oxidase-derived ROS.
Q47697277Complement receptor 3 mediates NADPH oxidase activation and dopaminergic neurodegeneration through a Src-Erk-dependent pathway
Q27674636Conformation-Sensing Antibodies Stabilize the Oxidized Form of PTP1B and Inhibit Its Phosphatase Activity
Q46133960Conformational changes in p47(phox) upon activation highlighted by mass spectrometry coupled to hydrogen/deuterium exchange and limited proteolysis
Q50605098Conservation of fungal and animal nicotinamide adenine dinucleotide phosphate oxidase complexes.
Q39646559Constitutive NADPH-dependent electron transferase activity of the Nox4 dehydrogenase domain
Q35996764Contribution of Dual Oxidase 2 (DUOX2) to Hyper-Radiosensitivity in Human Gastric Cancer Cells
Q37806640Contribution of neutrophils to acute lung injury
Q43294888Coordination of multiple dual oxidase-regulatory pathways in responses to commensal and infectious microbes in drosophila gut.
Q93173708Corosolic acid attenuates cardiac fibrosis following myocardial infarction in mice
Q38138198Coupling of transcriptional response to oxidative stress and secondary metabolism regulation in filamentous fungi
Q92253219Critical role of AMPK in redox regulation under glucose starvation
Q54212760Cross-talk between NADPH oxidase-PKCα-p(38)MAPK and NF-κB-MT1MMP in activating proMMP-2 by ET-1 in pulmonary artery smooth muscle cells.
Q38459968Crossroads of PI3K and Rac pathways.
Q35347850Crosstalk of reactive oxygen species and NF-κB signaling
Q50128069Crucial role of pro-inflammatory cytokines from respiratory tract upon PM2.5 exposure in causing the BMSCs differentiation in cells and animals.
Q54114905Cucurbitacin I Protects H9c2 Cardiomyoblasts against H2O2-Induced Oxidative Stress via Protection of Mitochondrial Dysfunction.
Q94594362Cumulative Effect of Cardiovascular Risk Factors on Regulation of AMPK/SIRT1-PGC-1α-SIRT3 Pathway in the Human Erectile Tissue
Q58781713Cxxc Finger Protein 1 Positively Regulates GM-CSF-Derived Macrophage Phagocytosis Through Csf2rα-Mediated Signaling
Q51423158Cyclometallated iridium complexes inducing paraptotic cell death like natural products: synthesis, structure and mechanistic aspects.
Q36941070Cysteine S-Glutathionylation Promotes Stability and Activation of the Hippo Downstream Effector Transcriptional Co-activator with PDZ-binding Motif (TAZ).
Q27652444Cysteine S-Nitrosylation Protects Protein-tyrosine Phosphatase 1B against Oxidation-induced Permanent Inactivation
Q24336189Cytokine activation of nuclear factor kappa B in vascular smooth muscle cells requires signaling endosomes containing Nox1 and ClC-3
Q37273230Cytokine-dependent regulation of NADPH oxidase activity and the consequences for activated T cell homeostasis
Q57471570Cytokines promote lipolysis in 3T3-L1 adipocytes through induction of NADPH oxidase 3 expression and superoxide production
Q42466993Cytosolic NADPH may regulate differences in basal Nox oxidase-derived superoxide generation in bovine coronary and pulmonary arteries
Q38359204Cytotoxin-induced NADPH oxides activation: roles in regulation of cell death
Q28828407DNA Phosphorothioate Modification Plays a Role in Peroxides Resistance in Streptomyces lividans
Q35723863DNA damage induces reactive oxygen species generation through the H2AX-Nox1/Rac1 pathway.
Q43180435DNA damage-induced reactive oxygen species (ROS) stress response in Saccharomyces cerevisiae
Q50191049DUAL OXIDASE: A NOVEL THERAPEUTIC TARGET IN ALLERGIC DISEASE.
Q49911371DeSUMOylation of MKK7 kinase by the SUMO2/3 protease SENP3 potentiates lipopolysaccharide-induced inflammatory signaling in macrophages.
Q45372352Dealing with radicals
Q36953180Decreased STAT5 phosphorylation and GATA-3 expression in NOX2-deficient T cells: role in T helper development
Q28588922Decreased blood pressure in NOX1-deficient mice
Q47149284Decreasing CB1 receptor signaling in Kupffer cells improves insulin sensitivity in obese mice
Q89983567Deep Evolutionary History of the Phox and Bem1 (PB1) Domain Across Eukaryotes
Q42703738Deficient DNA repair exacerbates ethanol-initiated DNA oxidation and embryopathies in ogg1 knockout mice: gender risk and protection by a free radical spin trapping agent
Q33551727Deficits in bioenergetics and impaired immune response in granulocytes from children with autism
Q37611952Degenerate cysteine patterns mediate two redox sensing mechanisms in the papillomavirus E7 oncoprotein.
Q35944830Deletion of Rac1GTPase in the Myeloid Lineage Protects against Inflammation-Mediated Kidney Injury in Mice
Q36670949Derivation and functional analysis of patient-specific induced pluripotent stem cells as an in vitro model of chronic granulomatous disease
Q92258088Detoxification, Apoptosis, and Immune Transcriptomic Responses of the Gill Tissue of Bay Scallop Following Exposure to the Algicide Thiazolidinedione 49
Q40960321Diabetes-induced oxidative stress mediates upregulation of RhoA/Rho kinase pathway and hypercontractility of gastric smooth muscle
Q37010269Diapocynin and apocynin administration fails to significantly extend survival in G93A SOD1 ALS mice
Q40142855Diesel exhaust particles induce matrix metalloprotease-1 in human lung epithelial cells via a NADP(H) oxidase/NOX4 redox-dependent mechanism.
Q40058708Differential expression of NADPH oxidase-2 (Nox-2) and nuclear factor-erythroid 2-related factor 2 (Nrf2) transcripts in peripheral blood mononuclear cells isolated from dengue patients
Q28585549Differential expression of NADPH oxidases in megakaryocytes and their role in polyploidy
Q37486498Differential macrophage function in Brown Swiss and Holstein Friesian cattle
Q41996938Diminished neutrophil extracellular trap (NET) formation is a novel innate immune deficiency induced by acute ethanol exposure in polymicrobial sepsis, which can be rescued by CXCL1
Q39039419Diphenyleneiodonium, an inhibitor of NOXes and DUOXes, is also an iodide-specific transporter
Q36065503Diquat causes caspase-independent cell death in SH-SY5Y cells by production of ROS independently of mitochondria
Q35830252Direct Comparison of a Natural Loss-Of-Function Single Nucleotide Polymorphism with a Targeted Deletion in the Ncf1 Gene Reveals Different Phenotypes
Q37146793Direct and specific inactivation of protein tyrosine kinases in the Src and FGFR families by reversible cysteine oxidation
Q24338017Direct interaction between Tks proteins and the N-terminal proline-rich region (PRR) of NoxA1 mediates Nox1-dependent ROS generation
Q45345920Direct involvement of the small GTPase Rac in activation of the superoxide-producing NADPH oxidase Nox1.
Q39511395Down-regulation of tumor-associated NADH oxidase, tNOX (ENOX2), enhances capsaicin-induced inhibition of gastric cancer cell growth
Q36853843Downregulation of p22phox in retinal pigment epithelial cells inhibits choroidal neovascularization in mice
Q33818148Downstream targets and intracellular compartmentalization in Nox signaling
Q28588484Dual oxidase regulates neutrophil recruitment in allergic airways
Q24306096Dual oxidase-2 has an intrinsic Ca2+-dependent H2O2-generating activity
Q24676778Dual oxidases
Q42854205Dual role of the p38 MAPK/cPLA2 pathway in the regulation of platelet apoptosis induced by ABT-737 and strong platelet agonists
Q28390372Dynamic redox control of NF-kappaB through glutaredoxin-regulated S-glutathionylation of inhibitory kappaB kinase beta
Q57031650EXPRESS: Hypoxia-induced pulmonary vasoconstriction of intra-acinar arteries is impaired in NADPH oxidase 4 gene-deficient mice
Q36059818Ebselen and congeners inhibit NADPH oxidase 2-dependent superoxide generation by interrupting the binding of regulatory subunits
Q45086298Ecabet sodium inhibits Helicobacter pylori lipopolysaccharide-induced activation of NADPH oxidase 1 or apoptosis of guinea pig gastric mucosal cells
Q46272229Effect of Particulate Matter Air Pollution on Cardiovascular Oxidative Stress Pathways
Q43242187Effect of endothelium-specific insulin resistance on endothelial function in vivo
Q34119306Effect of staurosporine in the morphology and viability of cerebellar astrocytes: role of reactive oxygen species and NADPH oxidase
Q40709563Effects of dietary supplementations with the fibrous root of Rhizoma Coptidis and its main alkaloids on non-specific immunity and disease resistance of common carp
Q33494075Effects of exogenous annexin-1 on lipopolysaccharide-induced proliferation and reactive oxygen species production partially through modulation of CRAC channels but independent of NF-kappaB pathway.
Q37217933Effects of spaceflight on innate immune function and antioxidant gene expression
Q35038216Electron and proton transport by NADPH oxidases
Q28392374Elevated hydrogen peroxide and decreased catalase and glutathione peroxidase protection are associated with aging sarcopenia
Q37648636Elimination of NADPH oxidase activity promotes reductive stress and sensitizes the heart to ischemic injury
Q64900172Emerging Roles of Redox-Mediated Angiogenesis and Oxidative Stress in Dermatoses.
Q42547767Emerging concepts in hypertension
Q36302828Emerging drugs for idiopathic pulmonary fibrosis
Q39580202Endogenous production of reactive oxygen species by the NADPH oxidase complexes is a determinant of γ-glutamyltransferase expression
Q28512867Endosomal NADPH oxidase regulates c-Src activation following hypoxia/reoxygenation injury
Q42702420Enhanced NADPH oxidases and reactive oxygen species in the mechanism of methanol-initiated protein oxidation and embryopathies in vivo and in embryo culture
Q39977710Enhanced expression of NADPH oxidase Nox4 in human gliomas and its roles in cell proliferation and survival
Q35157032Enhancement of Allergen-induced Airway Inflammation by NOX2 Deficiency
Q39184327Entamoeba histolytica induces cell death of HT29 colonic epithelial cells via NOX1-derived ROS.
Q35515708Enteric commensal bacteria induce extracellular signal-regulated kinase pathway signaling via formyl peptide receptor-dependent redox modulation of dual specific phosphatase 3.
Q93052272Environmental Exposures and Autoimmune Diseases: Contribution of Gut Microbiome
Q34046939Epidermal growth factor stimulates nuclear factor-κB activation and heme oxygenase-1 expression via c-Src, NADPH oxidase, PI3K, and Akt in human colon cancer cells
Q36260725Epigallocatechin-3-Gallate (EGCG) Attenuates Traumatic Brain Injury by Inhibition of Edema Formation and Oxidative Stress
Q33985960Epigallocatechin-3-gallate induces mesothelioma cell death via H2 O2 -dependent T-type Ca2+ channel opening.
Q34057126Epithelial adhesion mediated by pilin SpaC is required for Lactobacillus rhamnosus GG-induced cellular responses.
Q35312375Essential role of Duox in stabilization of Drosophila wing
Q46527889Essential role of NOXA1 in generation of reactive oxygen species induced by oxidized low-density lipoprotein in human vascular endothelial cells
Q38632920Estrogen potentiates reactive oxygen species (ROS) tolerance to initiate carcinogenesis and promote cancer malignant transformation
Q34113978Etanercept exacerbates inflammation and pathology in a rabbit model of active pulmonary tuberculosis
Q47273228Eukaryotic Cu-only superoxide dismutases (SODs): A new class of SOD enzymes and SOD-like protein domains
Q28506261Eukaryotic translation initiation factor 6 is a novel regulator of reactive oxygen species-dependent megakaryocyte maturation
Q36329753Evaluation of systemic markers of inflammation in atomic-bomb survivors with special reference to radiation and age effects
Q33311462Evasion of Legionella pneumophila from the bactericidal system by reactive oxygen species (ROS) in macrophages
Q33811991Evidence for a novel antioxidant function and isoform-specific regulation of the human p66Shc gene
Q36711277Evidence for a superoxide permeability pathway in endosomal membranes
Q64097775Evolutionary and functional analysis of the plant-specific NADPH oxidase gene family in L
Q36327246Evolutionary origin and function of NOX4-art, an arthropod specific NADPH oxidase
Q38041505Evolving concepts of oxidative stress and reactive oxygen species in cardiovascular disease.
Q27022081Execution of RIPK3-regulated necrosis
Q36846961Exogenous C2 Ceramide Suppresses Matrix Metalloproteinase Gene Expression by Inhibiting ROS Production and MAPK Signaling Pathways in PMA-Stimulated Human Astroglioma Cells
Q50422084Exosomes deliver ROS for regeneration.
Q38067944Expanding roles for GILT in immunity
Q34557682Expression and function of Noxo1gamma, an alternative splicing form of the NADPH oxidase organizer 1.
Q42484955Expression and modulation of an NADPH oxidase in mammalian astrocytes.
Q34089374Expression of Nox1 in 3T3 cells increases cellular acid production but not proton conductance
Q39904004Expression of amyotrophic lateral sclerosis-linked SOD1 mutant increases the neurotoxic potential of microglia via TLR2.
Q46735986Extracellular haem peroxidases mediate Mn(II) oxidation in a marine Roseobacter bacterium via superoxide production
Q46434762Extracellular matrix loss in chondrocytes after exposure to interleukin-1β in NADPH oxidase-dependent manner
Q40394667Extracellular matrix stimulates reactive oxygen species production and increases pancreatic cancer cell survival through 5-lipoxygenase and NADPH oxidase
Q40534991Extracellular superoxide dismutase attenuates lipopolysaccharide-induced neutrophilic inflammation
Q38283043FAK/Src family of kinases: protective or aggravating factor for ischemia reperfusion injury in nervous system?
Q39365101Facilitative functionalization of cyanine dye by an on-off-on fluorescent switch for imaging of H2O2 oxidative stress and thiols reducing repair in cells and tissues
Q92616828Fas-associated factor 1 mediates NADPH oxidase-induced reactive oxygen species production and proinflammatory responses in macrophages against Listeria infection
Q35064581Fast reactivity of a cyclic nitrone-calix[4]pyrrole conjugate with superoxide radical anion: theoretical and experimental studies
Q36303188Fast, Ultrasensitive Detection of Reactive Oxygen Species Using a Carbon Nanotube Based-Electrocatalytic Intracellular Sensor
Q35162073Features of microglia and neuroinflammation relevant to environmental exposure and neurotoxicity
Q38877279Fetal oxidative stress mechanisms of neurodevelopmental deficits and exacerbation by ethanol and methamphetamine.
Q83853842Fibrillar beta-amyloid-stimulated intracellular signaling cascades require Vav for induction of respiratory burst and phagocytosis in monocytes and microglia
Q38763973Fibroblast growth factor 2 protects against renal ischaemia/reperfusion injury by attenuating mitochondrial damage and proinflammatory signalling
Q39129812Fibroblast-to-myofibroblast switch is mediated by NAD(P)H oxidase generated reactive oxygen species.
Q38820927Fluorogenic nanoreactor assembly with boosted sensing kinetics for timely imaging of cellular hydrogen peroxide.
Q44787793Formation of protein S-nitrosylation by reactive oxygen species
Q33587373FoxO proteins restrain osteoclastogenesis and bone resorption by attenuating H2O2 accumulation
Q24633000Fragile x syndrome
Q33831873Free radical-operated proteotoxic stress in macrophages primed with lipopolysaccharide.
Q24299330From death receptor to reactive oxygen species and c-Jun N-terminal protein kinase: the receptor-interacting protein 1 odyssey
Q27643779Full-length p40phox structure suggests a basis for regulation mechanism of its membrane binding
Q37191663Function of reactive oxygen species during animal development: passive or active?
Q39334544Functional Role of Nox4 in Autophagy.
Q46813206Functional analysis of a fungal endophyte stress-activated MAP kinase.
Q41988250Functional analysis of the Trichoderma harzianum nox1 gene, encoding an NADPH oxidase, relates production of reactive oxygen species to specific biocontrol activity against Pythium ultimum
Q43552662Functional characterization of Rho GTPases in Aspergillus niger uncovers conserved and diverged roles of Rho proteins within filamentous fungi
Q37079939Fungal Endophyte Production of Reactive Oxygen Species is Critical for Maintaining the Mutualistic Symbiotic Interaction Between Epichloë festucae and Perennial Ryegrass
Q36499477Fungal antioxidant pathways promote survival against neutrophils during infection
Q33558138Fungal metabolite gliotoxin targets flavocytochrome b558 in the activation of the human neutrophil NADPH oxidase
Q42910631G protein-coupled receptor Ca2+-linked mitochondrial reactive oxygen species are essential for endothelial/leukocyte adherence
Q24621013G6PC3 mutations are associated with a major defect of glycosylation: a novel mechanism for neutrophil dysfunction
Q50986836Gene expression analysis illuminates the transcriptional programs underlying the functional activity of ex vivo-expanded granulocytes.
Q41328292Gene expression of NOX family members and their clinical significance in hepatocellular carcinoma.
Q34473374Gene therapy of chronic granulomatous disease: the engraftment dilemma
Q36818652Generation of Reactive Oxygen Species via NOXa Is Important for Development and Pathogenicity of Mycosphaerella graminicola
Q90681355Generation of Superoxide by OeRbohH, a NADPH Oxidase Activity During Olive (Olea europaea L.) Pollen Development and Germination
Q36020772Generation of reactive oxygen species in adipose-derived stem cells: friend or foe?
Q47584084Genetic depletion of glutathione peroxidase-1 potentiates nephrotoxicity induced by multiple doses of cocaine via activation of angiotensin II AT1 receptor
Q91361698Genetic polymorphisms associated with reactive oxygen species and blood pressure regulation
Q48744224Genetic polymorphisms of NAD(P)H oxidase: variation in subunit expression and enzyme activity.
Q37412182Genetic silencing of Nox2 and Nox4 reveals differential roles of these NADPH oxidase homologues in the vasopressor and dipsogenic effects of brain angiotensin II.
Q37176109Genetics and immunopathology of chronic granulomatous disease
Q30379938Genomic analysis of xCT-mediated regulatory network: Identification of novel targets against AIDS-associated lymphoma.
Q95940280Genomic innovation of ATD alleviates mistranslation associated with multicellularity in Animalia
Q58775273Glial responses during epileptogenesis in Mus musculus point to potential therapeutic targets
Q28580369Glutaredoxin modulates platelet-derived growth factor-dependent cell signaling by regulating the redox status of low molecular weight protein-tyrosine phosphatase
Q45768550Glutaredoxin-2 controls cardiac mitochondrial dynamics and energetics in mice, and protects against human cardiac pathologies
Q90001228Glutathione Reductase Promotes Fungal Clearance and Suppresses Inflammation during Systemic Candida albicans Infection in Mice
Q39877920Glutathione peroxidase-1 regulates mitochondrial function to modulate redox-dependent cellular responses
Q24623844Glutathione reductase facilitates host defense by sustaining phagocytic oxidative burst and promoting the development of neutrophil extracellular traps
Q51760765Glycerophospholipid Supplementation as a Potential Intervention for Supporting Cerebral Structure in Older Adults.
Q43042639Glycogen synthase kinase 3beta and beta-catenin pathway is involved in toll-like receptor 4-mediated NADPH oxidase 1 expression in macrophages
Q40217658Glycolysis regulates the expansion of myeloid-derived suppressor cells in tumor-bearing hosts through prevention of ROS-mediated apoptosis
Q83412162Gp91(phox) contributes to the development of experimental inflammatory bowel disease
Q39744997Granzyme B of cytotoxic T cells induces extramitochondrial reactive oxygen species production via caspase-dependent NADPH oxidase activation.
Q44822360Graphene quantum dots/gold electrode and its application in living cell H2O2 detection
Q38532119Group VIA phospholipase A2 mediates enhanced macrophage migration in diabetes mellitus by increasing expression of nicotinamide adenine dinucleotide phosphate oxidase 4.
Q45232121H(2)O(2): a mediator of esophagitis-induced damage to calcium-release mechanisms in cat lower esophageal sphincter
Q35975966H2O2: a dynamic neuromodulator
Q46913608HCl-induced inflammatory mediators in cat esophageal mucosa and inflammatory mediators in esophageal circular muscle in an in vitro model of esophagitis
Q34178917HCl-induced inflammatory mediators in esophageal mucosa increase migration and production of H2O2 by peripheral blood leukocytes.
Q92576657HPLC-Based Monitoring of Oxidation of Hydroethidine for the Detection of NADPH Oxidase-Derived Superoxide Radical Anion
Q33257260Harmful waste products as novel immune modulators for treating inflammatory arthritis?
Q27005955Heart failure and mitochondrial dysfunction: the role of mitochondrial fission/fusion abnormalities and new therapeutic strategies
Q43132399Heat shock protein gp96 and NAD(P)H oxidase 4 play key roles in Toll-like receptor 4-activated apoptosis during renal ischemia/reperfusion injury
Q37785807Helicobacter pylori: a ROS-inducing bacterial species in the stomach.
Q34805528Heme oxygenase-1 regulates matrix metalloproteinase MMP-1 secretion and chondrocyte cell death via Nox4 NADPH oxidase activity in chondrocytes
Q64234636Heme peroxidase HPX-2 protects Caenorhabditis elegans from pathogens
Q35893594Hepatocyte Nicotinamide Adenine Dinucleotide Phosphate Reduced Oxidase 4 Regulates Stress Signaling, Fibrosis, and Insulin Sensitivity During Development of Steatohepatitis in Mice.
Q37051544Hepatocytes produce TNF-α following hypoxia-reoxygenation and liver ischemia-reperfusion in a NADPH oxidase- and c-Src-dependent manner
Q92576720High-Throughput Screening of NOX Inhibitors
Q33718483High-throughput assays for superoxide and hydrogen peroxide: design of a screening workflow to identify inhibitors of NADPH oxidases.
Q41791230Hsp90 regulates NADPH oxidase activity and is necessary for superoxide but not hydrogen peroxide production
Q34369955Human adipose tissue-derived multilineage progenitor cells exposed to oxidative stress induce neurite outgrowth in PC12 cells through p38 MAPK signaling
Q64764525Human myeloperoxidase (hMPO) is expressed in neurons in the substantia nigra in Parkinson's disease and in the hMPO-α-synuclein-A53T mouse model, correlating with increased nitration and aggregation of α-synuclein and exacerbation of motor impairmen
Q26787065Hydrogen peroxide - production, fate and role in redox signaling of tumor cells
Q42834383Hydrogen peroxide induces hyphal differentiation in Candida albicans
Q37942731Hydrogen peroxide: a Jekyll and Hyde signalling molecule
Q37011787Hydropropidine: a novel, cell-impermeant fluorogenic probe for detecting extracellular superoxide.
Q37768423Hyperoxia sensing: from molecular mechanisms to significance in disease
Q35708477Hyperoxia-Induced Protein Alterations in Renal Rat Tissue: A Quantitative Proteomic Approach to Identify Hyperoxia-Induced Effects in Cellular Signaling Pathways
Q36087186Hyphopodium-Specific VdNoxB/VdPls1-Dependent ROS-Ca2+ Signaling Is Required for Plant Infection by Verticillium dahliae
Q42163271Hypoosmotic swelling and ammonia increase oxidative stress by NADPH oxidase in cultured astrocytes and vital brain slices
Q34977591Hypoxia and metabolic factors that influence inflammatory bowel disease pathogenesis.
Q46835597Hypoxic culture conditions enhance the generation of regulatory T cells
Q33844913IFNgamma mediates DUOX2 expression via a STAT-independent signaling pathway
Q47564540IKKα inactivation promotes Kras-initiated lung adenocarcinoma development through disrupting major redox regulatory pathways
Q45960055IL-17 stimulates the proliferation and differentiation of human mesenchymal stem cells: implications for bone remodeling.
Q34306241Ibuprofen attenuates oxidative damage through NOX2 inhibition in Alzheimer's disease
Q58118405Identification of NoxD/Pro41 as the homologue of the p22phoxNADPH oxidase subunit in fungi
Q24311930Identification of a conserved Rac-binding site on NADPH oxidases supports a direct GTPase regulatory mechanism
Q36288338Idh1 protects murine hepatocytes from endotoxin-induced oxidative stress by regulating the intracellular NADP(+)/NADPH ratio.
Q37787832Immune homeostasis to microorganisms in the guts of triatomines (Reduviidae)--a review.
Q47162715Immune-related redox metabolism of embryonic cells of the tick Rhipicephalus microplus (BME26) in response to infection with Anaplasma marginale.
Q39271619Immunobiology of Nitric Oxide and Regulation of Inducible Nitric Oxide Synthase
Q35200898Impact of Nox5 polymorphisms on basal and stimulus-dependent ROS generation
Q35114807Impact of hypothalamic reactive oxygen species in the regulation of energy metabolism and food intake
Q34013764Impaired OXPHOS complex III in breast cancer
Q37069112Impaired priming and activation of the neutrophil NADPH oxidase in patients with IRAK4 or NEMO deficiency
Q34564985Independent evaluation of low-level laser therapy at 635 nm for non-invasive body contouring of the waist, hips, and thighs
Q89434587Indoxyl Sulfate, a Uremic Toxin, Stimulates Reactive Oxygen Species Production and Erythrocyte Cell Death Supposedly by an Organic Anion Transporter 2 (OAT2) and NADPH Oxidase Activity-Dependent Pathways
Q58766159Induces Intervertebral Disc Degeneration by Promoting iNOS/NO and COX-2/PGE Activation via the ROS-Dependent NF-B Pathway
Q33954239Inducible nitric oxide synthase is key to peroxynitrite-mediated, LPS-induced protein radical formation in murine microglial BV2 cells.
Q46383587Inducible nitric oxide synthase-dependent DNA damage in mouse model of inflammatory bowel disease
Q38925164Induction of apoptosis in Caco-2 cells by exogenously added O₂⁻ produced by a nanodevice
Q42083816Inflammasome activation in NADPH oxidase defective mononuclear phagocytes from patients with chronic granulomatous disease
Q38083584Inflammation and oxidative stress in angiogenesis and vascular disease.
Q41996786Inflammation and oxidative stress induced by cigarette smoke in Lewis rat brains
Q89487277Inhibiting the Activity of NADPH Oxidase in Cancer
Q47114223Inhibition of HOX/PBX dimer formation leads to necroptosis in acute myeloid leukemia cells
Q54956883Inhibition of NADPH oxidase 2 induces apoptosis in osteosarcoma: The role of reactive oxygen species in cell proliferation.
Q40305878Inhibition of NADPH oxidase 4 activates apoptosis via the AKT/apoptosis signal-regulating kinase 1 pathway in pancreatic cancer PANC-1 cells.
Q64228774Inhibition of NADPH oxidase by apocynin prevents learning and memory deficits in a mouse Parkinson's disease model
Q37322537Inhibition of NADPH oxidase is neuroprotective after ischemia-reperfusion
Q39871164Inhibition of insulin-stimulated hydrogen peroxide production prevents stimulation of sodium transport in A6 cell monolayers
Q37486972Inhibition of nuclear Nox4 activity by plumbagin: effect on proliferative capacity in human amniotic stem cells
Q34983695Inhibition of oxidative stress-elicited AKT activation facilitates PPARγ agonist-mediated inhibition of stem cell character and tumor growth of liver cancer cells
Q28082229Inhibitory and excitatory neuromodulation by hydrogen peroxide: translating energetics to information
Q33612089Initial Spore Density Has an Influence on Ochratoxin A Content in Aspergillus ochraceus CGMCC 3.4412 in PDB and Its Interaction with Seeds
Q52720174Insights on Localized and Systemic Delivery of Redox-Based Therapeutics.
Q34562786Insulin-induced vascular endothelial growth factor expression is mediated by the NADPH oxidase NOX3.
Q38840303Integrated High-Content Quantification of Intracellular ROS Levels and Mitochondrial Morphofunction
Q24319711Interaction between the SH3 domains and C-terminal proline-rich region in NADPH oxidase organizer 1 (Noxo1)
Q46933998Interaction of NADPH oxidase 1 with Toll-like receptor 2 induces migration of smooth muscle cells
Q42875767Interfering with ROS Metabolism in Cancer Cells: The Potential Role of Quercetin.
Q46004587Interferon-alpha2b (IFN-alpha2b)-induced apoptosis is mediated by p38 MAPK in hepatocytes from rat preneoplastic liver via activation of NADPH oxidase.
Q40373525Interferon-gamma activates transcription of NADPH oxidase 1 gene and upregulates production of superoxide anion by human large intestinal epithelial cells
Q34114819Interferon-inducible effector mechanisms in cell-autonomous immunity
Q43284434Interleukin 10 inhibits interferon gamma- and tumor necrosis factor alpha-stimulated activation of NADPH oxidase 1 in human colonic epithelial cells and the mouse colon
Q24294812Interleukin-1beta induction of NFkappaB is partially regulated by H2O2-mediated activation of NFkappaB-inducing kinase
Q37668153Interleukin-27 Enhances the Potential of Reactive Oxygen Species Generation from Monocyte-derived Macrophages and Dendritic cells by Induction of p47phox
Q90334233Interplay between BMPs and Reactive Oxygen Species in Cell Signaling and Pathology
Q37589624Interplay between calcium and reactive oxygen/nitrogen species: an essential paradigm for vascular smooth muscle signaling
Q54268648Interplay between enterobactin, myeloperoxidase and lipocalin 2 regulates E. coli survival in the inflamed gut.
Q91830598Interplay of oxidative stress and antioxidant bio markers in oil adjuvant Brucella melitensis vaccinated and challenged mice
Q34724693Intestinal NADPH oxidase 2 activity increases in a neonatal rat model of necrotizing enterocolitis.
Q35257518Intracellular free radical production by peripheral blood T lymphocytes from patients with systemic sclerosis: role of NADPH oxidase and ERK1/2.
Q54976919Involvement of NADPH oxidase 1 in UVB-induced cell signaling and cytotoxicity in human keratinocytes.
Q24548021Involvement of Rac1 in activation of multicomponent Nox1- and Nox3-based NADPH oxidases
Q48218398Involvement of superoxide generated by NADPH oxidase in the shedding of procoagulant vesicles from human monocytic cells exposed to bupivacaine
Q54967728Ischemia-reperfusion Injury in the Brain: Mechanisms and Potential Therapeutic Strategies.
Q35113412Ischemia/reperfusion injury and cardioprotective mechanisms: Role of mitochondria and reactive oxygen species
Q35332267Isoprostane generation and function
Q34442336Japanese encephalitis virus induces matrix metalloproteinase-9 in rat brain astrocytes via NF-κB signalling dependent on MAPKs and reactive oxygen species.
Q36134231KLHDC10 Deficiency Protects Mice against TNFα-Induced Systemic Inflammation
Q36200269Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity
Q37222183Kupffer cells in non-alcoholic fatty liver disease: the emerging view.
Q21132331Lactate regulates rat male germ cell function through reactive oxygen species
Q38222431Life-history Constraints on the Mechanisms that Control the Rate of ROS Production
Q34630500Light-activated regulation of cofilin dynamics using a photocaged hydrogen peroxide generator
Q37677270Linking oxidative stress to inflammation: Toll-like receptors
Q37446112Lipid rafts and caveolin-1 coordinate interleukin-1beta (IL-1beta)-dependent activation of NFkappaB by controlling endocytosis of Nox2 and IL-1beta receptor 1 from the plasma membrane
Q50066600Lipopolysaccharides trigger two successive bursts of reactive oxygen species at distinct cellular locations.
Q30412063Lipoteichoic acid (LTA) and lipopolysaccharides (LPS) from periodontal pathogenic bacteria facilitate oncogenic herpesvirus infection within primary oral cells
Q35608796Lipotoxicity augments glucotoxicity-induced mitochondrial damage in the development of diabetic retinopathy
Q27322639Live imaging of innate immune cell sensing of transformed cells in zebrafish larvae: parallels between tumor initiation and wound inflammation
Q37734352Long-Term Effects of Maternal Deprivation on Redox Regulation in Rat Brain: Involvement of NADPH Oxidase.
Q93179119Loss of Scribble confers cisplatin resistance during NSCLC chemotherapy via Nox2/ROS and Nrf2/PD-L1 signaling
Q36423420Low extracellular zinc increases neuronal oxidant production through nadph oxidase and nitric oxide synthase activation
Q35993498Lung Mucosa Lining Fluid Modification of Mycobacterium tuberculosis to Reprogram Human Neutrophil Killing Mechanisms
Q37688764Luteolin-7-diglucuronide attenuates isoproterenol-induced myocardial injury and fibrosis in mice
Q40043141Lymphocytic microparticles inhibit angiogenesis by stimulating oxidative stress and negatively regulating VEGF-induced pathways
Q46565025MAPK signaling regulates nitric oxide and NADPH oxidase-dependent oxidative bursts in Nicotiana benthamiana.
Q39478384MC1R expression in HaCaT keratinocytes inhibits UVA-induced ROS production via NADPH oxidase- and cAMP-dependent mechanisms
Q24301822MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca(2+) uptake that regulates cell survival
Q40081397MKK6 phosphorylation regulates production of superoxide by enhancing Rac GTPase activity
Q61796006Macrophage achieves self-protection against oxidative stress-induced ageing through the Mst-Nrf2 axis
Q36339228Macrophage depletion lowers blood pressure and restores sympathetic nerve α2-adrenergic receptor function in mesenteric arteries of DOCA-salt hypertensive rats
Q36978237Macrophage glucose-6-phosphate dehydrogenase stimulates proinflammatory responses with oxidative stress.
Q34793732Macrophage-specific NOX2 contributes to the development of lung emphysema through modulation of SIRT1/MMP-9 pathways
Q35679575Magmas functions as a ROS regulator and provides cytoprotection against oxidative stress-mediated damages
Q36909558Magnaporthe oryzae Effector AVR-Pii Helps to Establish Compatibility by Inhibition of the Rice NADP-Malic Enzyme Resulting in Disruption of Oxidative Burst and Host Innate Immunity.
Q41921890Maintaining system homeostasis: the third law of Newtonian immunology
Q44172726Malaria circumsporozoite protein inhibits the respiratory burst in Kupffer cells
Q80391517Mass spectrometry-based analyses for identifying and characterizing S-nitrosylation of protein tyrosine phosphatases
Q34764783Matrix metalloproteinase-3 causes dopaminergic neuronal death through Nox1-regenerated oxidative stress
Q35762929Mechanism of all-trans-retinal toxicity with implications for stargardt disease and age-related macular degeneration
Q40057005Mechanism of angiotensin II-induced superoxide production in cells reconstituted with angiotensin type 1 receptor and the components of NADPH oxidase
Q26864358Mechanisms and potential therapeutic applications of microglial activation after brain injury
Q26779214Mechanisms of Control of Mycobacterium tuberculosis by NK Cells: Role of Glutathione
Q28397657Mechanisms of Peroxynitrite Interactions with Heme Proteins
Q40387534Mechanisms of statin-mediated inhibition of small G-protein function
Q40751148Mechanisms of vascular dysfunction in acute phase of Trypanosoma cruzi infection in mice.
Q26996553Medicinal plant activity on Helicobacter pylori related diseases
Q92693995Metabolic comparison of aerial and submerged mycelia formed in the liquid surface culture of Cordyceps militaris
Q40480159Metabolic flux analyses of Pseudomonas aeruginosa cystic fibrosis isolates.
Q37364839Metabolic response to glatiramer acetate therapy in multiple sclerosis patients.
Q39343660Metabolic rewiring in mutant Kras lung cancer
Q83232771Metabolite imaging: knock, nox-ROS there?
Q46238652Metformin Mediates Protection against Legionella Pneumonia through Activation of AMPK and Mitochondrial Reactive Oxygen Species.
Q34276500Methionine sulfoxide reductase A down-regulation in human breast cancer cells results in a more aggressive phenotype
Q36227353Methods to monitor classical protein-tyrosine phosphatase oxidation.
Q28658683Methyl jasmonate: putative mechanisms of action on cancer cells cycle, metabolism, and apoptosis
Q40756383Methyl-esterified 3-hydroxybutyrate oligomers protect bacteria from hydroxyl radicals
Q33934226Microarray expression profiling of Spodoptera litura in response to oxidative stress
Q33943525Microbes in gastrointestinal health and disease
Q36155964Microbicidal activity of vascular peroxidase 1 in human plasma via generation of hypochlorous acid.
Q46808883Microbicidal protein psoriasin is a multifunctional modulator of neutrophil activation
Q37794381Microglial activation in stroke: therapeutic targets
Q49571710Mitigating the Impact of Antibacterial Drug Resistance through Host-Directed Therapies: Current Progress, Outlook, and Challenges.
Q35912784Mitigation of NADPH Oxidase 2 Activity as a Strategy to Inhibit Peroxynitrite Formation.
Q35976043Mitochondria and Oxidative Stress in the Cardiorenal Metabolic Syndrome
Q33940987Mitochondria are the source of hydrogen peroxide for dynamic brain-cell signaling
Q27005632Mitochondria as a therapeutic target in heart failure
Q34000569Mitochondria contribute to LPS-induced MAPK activation via uncoupling protein UCP2 in macrophages
Q34799187Mitochondria in innate immune responses
Q91231275Mitochondria in innate immune signaling
Q42703400Mitochondria-targeted antioxidant SkQ1 improves impaired dermal wound healing in old mice.
Q33675606Mitochondrial DNA polymorphism and risk of cancer
Q52627693Mitochondrial ROS cause motor deficits induced by synaptic inactivity: Implications for synapse pruning.
Q38907926Mitochondrial function, ornamentation, and immunocompetence
Q50516646Mitochondrial reactive oxygen species (ROS) inhibition ameliorates palmitate-induced INS-1 beta cell death.
Q34345639Mitochondrial reactive oxygen species modulate mosquito susceptibility to Plasmodium infection
Q34681297Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)
Q34462921Mitochondrial redox potential during contraction in single intact muscle fibers
Q37863124Mitochondrion: an emerging platform critical for host antiviral signaling
Q35055306Modulation and Interaction of Immune-Associated Parameters with Antioxidant in the Immunocytes of Crab Scylla paramamosain Challenged with Lipopolysaccharides
Q39756176Modulation of antioxidant defense in Aspergillus parasiticus is involved in aflatoxin biosynthesis: a role for the ApyapA gene
Q28574306Modulation of chronic hypoxia-induced chemoreceptor hypersensitivity by NADPH oxidase subunits in rat carotid body
Q36616362Modulation of microglial pro-inflammatory and neurotoxic activity for the treatment of Parkinson's disease
Q34541203Modulation of redox signaling promotes apoptosis in epithelial ovarian cancer cells
Q46680529Molecular Cloning and Expression Analysis of a Catalase Gene (NnCAT) from Nelumbo nucifera
Q38132124Molecular Genetics of Emericella nidulans Sexual Development
Q37637768Molecular and Histopathological Changes Associated with Keratoconus.
Q34925074Molecular cloning and functional characterization of the dual oxidase (BmDuox) gene from the silkworm Bombyx mori
Q33300608Molecular evolution of Phox-related regulatory subunits for NADPH oxidase enzymes
Q33290000Molecular evolution of the reactive oxygen-generating NADPH oxidase (Nox/Duox) family of enzymes
Q39886272Monitoring starvation-induced reactive oxygen species formation
Q39927509Mouse neutrophil extracellular traps in microbial infections.
Q90573177Multiple mechanisms involved in a low concentration of FL118 enhancement of AMR-MeOAc to induce pancreatic cancer cell apoptosis and growth inhibition
Q41688477Muscle Weakness in Rheumatoid Arthritis: The Role of Ca2+ and Free Radical Signaling.
Q35834462Muscle dysfunction associated with adjuvant-induced arthritis is prevented by antioxidant treatment
Q28269693Mutation of the Cyba gene encoding p22phox causes vestibular and immune defects in mice
Q36637889Mutual cross-talk between reactive oxygen species and nuclear factor-kappa B: molecular basis and biological significance
Q28540070Mycobacteria counteract a TLR-mediated nitrosative defense mechanism in a zebrafish infection model
Q33665347Mycobacterium tuberculosis Induction of Heme Oxygenase-1 Expression Is Dependent on Oxidative Stress and Reflects Treatment Outcomes
Q38223250Myeloid-derived suppressor cell heterogeneity in human cancers
Q38644482Myeloid-specific deletion of NOX2 prevents the metabolic and neurologic consequences of high fat diet.
Q33924362Myeloperoxidase-induced genomic DNA-centered radicals
Q43105929NAD(P)H oxidase and pro-inflammatory response during maximal exercise: role of C242T polymorphism of the P22PHOX subunit.
Q33593365NAD(P)H oxidases in coronary artery disease.
Q35934016NADPH Oxidase 1 Is Associated with Altered Host Survival and T Cell Phenotypes after Influenza A Virus Infection in Mice
Q40966286NADPH Oxidase 1 and NADPH Oxidase 4 Have Opposite Prognostic Effects for Patients with Hepatocellular Carcinoma after Hepatectomy
Q93174195NADPH Oxidase 1 in Liver Macrophages Promotes Inflammation and Tumor Development in Mice
Q99605324NADPH Oxidase 5 Is Essential for Molting and Oviposition in a Rice Planthopper Nilaparvata lugens
Q39227213NADPH Oxidase Inhibitor Apocynin Attenuates PCB153-Induced Thyroid Injury in Rats.
Q58699302NADPH Oxidase and Guanylate Binding Protein 5 Restrict Survival of Avirulent Type III Strains of Toxoplasma gondii in Naive Macrophages
Q39496194NADPH Oxidase as a Therapeutic Target for Neuroprotection against Ischaemic Stroke: Future Perspectives.
Q26749539NADPH Oxidase-Dependent Superoxide Production in Plant Reproductive Tissues
Q26768464NADPH Oxidase: A Potential Target for Treatment of Stroke
Q38038888NADPH Oxidases NOXs and DUOXs as putative targets for cancer therapy.
Q38599090NADPH Oxidases in Chronic Liver Diseases
Q89761945NADPH Oxidases: The Vital Performers and Center Hubs during Plant Growth and Signaling
Q30488554NADPH oxidase 1 controls the persistence of directed cell migration by a Rho-dependent switch of alpha2/alpha3 integrins.
Q39362677NADPH oxidase 1 overexpression enhances invasion via matrix metalloproteinase-2 and epithelial-mesenchymal transition in melanoma cells
Q46613957NADPH oxidase 1 plays a critical mediating role in oncogenic Ras-induced vascular endothelial growth factor expression
Q33666145NADPH oxidase 1 supports proliferation of colon cancer cells by modulating reactive oxygen species-dependent signal transduction
Q34093188NADPH oxidase 2-derived reactive oxygen species in spinal cord microglia contribute to peripheral nerve injury-induced neuropathic pain
Q37510779NADPH oxidase 4 deficiency reduces aquaporin-2 mRNA expression in cultured renal collecting duct principal cells via increased PDE3 and PDE4 activity
Q34581756NADPH oxidase 4 is an oncoprotein localized to mitochondria
Q40119845NADPH oxidase 4 is required for the generation of macrophage migration inhibitory factor and host defense against Toxoplasma gondii infection.
Q46024987NADPH oxidase 4 modulates hepatic responses to lipopolysaccharide mediated by Toll-like receptor-4.
Q24299314NADPH oxidase 5 (NOX5) interacts with and is regulated by calmodulin
Q40150850NADPH oxidase NOX5-S mediates acid-induced cyclooxygenase-2 expression via activation of NF-kappaB in Barrett's esophageal adenocarcinoma cells
Q28392194NADPH oxidase activation is required in reactive oxygen species generation and cell transformation induced by hexavalent chromium
Q37766127NADPH oxidase and cardiac failure.
Q38111373NADPH oxidase and neurodegeneration
Q27014373NADPH oxidase as a therapeutic target for oxalate induced injury in kidneys
Q42698788NADPH oxidase expression and production of superoxide by human corneal stromal cells.
Q26859140NADPH oxidase in stroke and cerebrovascular disease
Q43010140NADPH oxidase inhibition ameliorates cardiac dysfunction in rabbits with heart failure
Q37873495NADPH oxidase inhibitors: a patent review
Q30505392NADPH oxidase is internalized by clathrin-coated pits and localizes to a Rab27A/B GTPase-regulated secretory compartment in activated macrophages
Q40021844NADPH oxidase limits lipopolysaccharide-induced lung inflammation and injury in mice through reduction-oxidation regulation of NF-κB activity
Q42276215NADPH oxidase mediates beta-amyloid peptide-induced activation of ERK in hippocampal organotypic cultures
Q39316165NADPH oxidase mediates depressive behavior induced by chronic stress in mice.
Q37449222NADPH oxidase signaling and cardiac myocyte function.
Q28588550NADPH oxidase-1 plays a crucial role in hyperoxia-induced acute lung injury in mice
Q34802636NADPH oxidase-2: linking glucose, acidosis, and excitotoxicity in stroke
Q37345265NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury.
Q34241578NADPH oxidase-4 mediates protection against chronic load-induced stress in mouse hearts by enhancing angiogenesis.
Q42087034NADPH oxidase-dependent reactive oxygen species mediate amplified TLR4 signaling and sepsis-induced mortality in Nrf2-deficient mice
Q61862473NADPH oxidase-dependent redox signaling in human heart failure: Relationship between the left and right ventricle
Q41089726NADPH oxidase-derived overproduction of reactive oxygen species impairs postischemic neovascularization in mice with type 1 diabetes.
Q64935063NADPH oxidase-derived reactive oxygen species are involved in the HL-60 cell monocytic differentiation induced by isoliquiritigenin.
Q36328374NADPH oxidase-derived reactive oxygen species in cardiac pathophysiology
Q34566569NADPH oxidase-derived reactive oxygen species mediate decidualization of human endometrial stromal cells in response to cyclic AMP signaling.
Q36846189NADPH oxidases NOX-1 and NOX-2 require the regulatory subunit NOR-1 to control cell differentiation and growth in Neurospora crassa.
Q38394359NADPH oxidases and cancer
Q37775558NADPH oxidases and cardiac remodelling
Q38054458NADPH oxidases as a source of oxidative stress and molecular target in ischemia/reperfusion injury
Q35145985NADPH oxidases in cardiovascular disease: insights from in vivo models and clinical studies.
Q27001094NADPH oxidases in heart failure: poachers or gamekeepers?
Q36571169NADPH oxidases in lung biology and pathology: host defense enzymes, and more
Q27027435NADPH oxidases in lung health and disease
Q38691764NADPH oxidases in oxidant production by microglia: activating receptors, pharmacology and association with disease
Q52344406NADPH oxidases in traumatic brain injury - Promising therapeutic targets?
Q33834313NADPH oxidases regulate cell growth and migration in myeloid cells transformed by oncogenic tyrosine kinases
Q36637317NADPH oxidases regulate septin-mediated cytoskeletal remodeling during plant infection by the rice blast fungus
Q28072348NADPH oxidases: key modulators in aging and age-related cardiovascular diseases?
Q39988593NADPH oxidases: molecular understanding finally reaching the clinical level?
Q38833270NADPH oxidases: new actors in thyroid cancer?
Q35915855NADPH oxidases: new regulators of old functions
Q35028232NADPH-oxidase activation and cognition in Alzheimer disease progression
Q31148000NADPH-oxidase-derived reactive oxygen species mediate the cerebrovascular dysfunction induced by the amyloid beta peptide.
Q92069747NF-kB as a key player in regulation of cellular radiation responses and identification of radiation countermeasures
Q34541717NLRP3 inflammasome activation by mitochondrial ROS in bronchial epithelial cells is required for allergic inflammation
Q41128491NOX Inhibitors - A Promising Avenue for Ischemic Stroke.
Q33872667NOX activity in brain aging: exacerbation by high fat diet.
Q37169101NOX enzymes and Toll-like receptor signaling.
Q37167303NOX enzymes and diabetic complications
Q33649864NOX enzymes and pulmonary disease
Q28266600NOX enzymes as drug targets
Q37176104NOX enzymes as novel targets for drug development
Q38009734NOX enzymes: potential target for the treatment of acute lung injury
Q26798744NOX signaling in molecular cardiovascular mechanisms involved in the blood pressure homeostasis
Q89738567NOX1 Regulates Collective and Planktonic Cell Migration: Insights From Patients With Pediatric-Onset IBD and NOX1 Deficiency
Q46197743NOX1 loss-of-function genetic variants in patients with inflammatory bowel disease.
Q28544991NOX1 supports the metabolic remodeling of HepG2 cells
Q40717535NOX1/2 activation in human gingival fibroblasts by Fusobacterium nucleatum facilitates attachment of Porphyromonas gingivalis
Q39302060NOX2 (gp91phox) is a predominant O2 sensor in a human airway chemoreceptor cell line: biochemical, molecular, and electrophysiological evidence
Q30277768NOX2 Activation of Natural Killer T Cells Is Blocked by the Adenosine A2A Receptor to Inhibit Lung Ischemia-Reperfusion Injury
Q35985407NOX2 As a Target for Drug Development: Indications, Possible Complications, and Progress
Q42201999NOX2 Inhibition Impairs Early Muscle Gene Expression Induced by a Single Exercise Bout
Q36593089NOX2 deficiency attenuates markers of adiposopathy and brain injury induced by high-fat diet
Q35757129NOX2 deficiency protects against streptozotocin-induced beta-cell destruction and development of diabetes in mice
Q37576070NOX2 in lung inflammation: quantum dot based in situ imaging of NOX2-mediated expression of vascular cell adhesion molecule-1
Q28581584NOX2, p22phox and p47phox are targeted to the nuclear pore complex in ischemic cardiomyocytes colocalizing with local reactive oxygen species
Q46376898NOX2-dependent ATM kinase activation dictates pro-inflammatory macrophage phenotype and improves effectiveness to radiation therapy
Q35766055NOX2-derived reactive oxygen species are crucial for CD29-induced pro-survival signalling in cardiomyocytes
Q40133141NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation.
Q37256737NOX4 mediates cytoprotective autophagy induced by the EGFR inhibitor erlotinib in head and neck cancer cells.
Q37138896NOX4 mediates hypoxia-induced proliferation of human pulmonary artery smooth muscle cells: the role of autocrine production of transforming growth factor-{beta}1 and insulin-like growth factor binding protein-3.
Q34415231NOX4/NADPH oxidase expression is increased in pulmonary fibroblasts from patients with idiopathic pulmonary fibrosis and mediates TGFbeta1-induced fibroblast differentiation into myofibroblasts.
Q92435854NOX5 as a therapeutic target in cerebral ischemic injury
Q36221462NRROS Negatively Regulates Osteoclast Differentiation by Inhibiting RANKL-Mediated NF-N:B and Reactive Oxygen Species Pathways
Q28587529NRROS negatively regulates reactive oxygen species during host defence and autoimmunity
Q35786768Nadph oxidase regulates alveolar epithelial sodium channel activity and lung fluid balance in vivo via O⁻₂ signaling
Q35833987Naloxone inhibits immune cell function by suppressing superoxide production through a direct interaction with gp91phox subunit of NADPH oxidase
Q38563026Nanomedicine in the ROS-mediated pathophysiology: Applications and clinical advances.
Q58108554Naringenin mitigates titanium dioxide (TiO)-induced chronic arthritis in mice: role of oxidative stress, cytokines, and NFκB
Q42363693Neferine ameliorates cardiomyoblast apoptosis induced by doxorubicin: possible role in modulating NADPH oxidase/ROS-mediated NFκB redox signaling cascade
Q34073807Negative regulation of NADPH oxidase 4 by hydrogen peroxide-inducible clone 5 (Hic-5) protein
Q91744388Neuroendocrine drivers of risk and resilience: The influence of metabolism & mitochondria
Q57811980Neuroinflammation, oxidative stress, and blood-brain barrier (BBB) disruption in acute Utah electrode array implants and the effect of deferoxamine as an iron chelator on acute foreign body response
Q36390590Neuronal NAD(P)H oxidases contribute to ROS production and mediate RGC death after ischemia
Q64074388Neutrophil Cytosolic Factor 1 in Dendritic Cells Promotes Autoreactive CD8 T Cell Activation via Cross-Presentation in Type 1 Diabetes
Q37406391Neutrophil-mediated lung permeability and host defense proteins
Q36025303Neutrophil-mediated oxidative burst and host defense are controlled by a Vav-PLCgamma2 signaling axis in mice
Q29617616Neutrophils and immunity: challenges and opportunities
Q36228786Neutrophils from p40phox-/- mice exhibit severe defects in NADPH oxidase regulation and oxidant-dependent bacterial killing.
Q40054491Neutrophils to the ROScue: Mechanisms of NADPH Oxidase Activation and Bacterial Resistance
Q38585102Neutrophils: important contributors to tumor progression and metastasis.
Q92135848New Therapeutic Targets in Autoimmune Cholangiopathies
Q37598306New insights into molecular mechanisms of diabetic kidney disease
Q30573843New insights into the roles of NADPH oxidases in sexual development and ascospore germination in Sordaria macrospora.
Q36834142New tricks from an old dog: mitochondrial redox signaling in cellular inflammation.
Q64111059Nicorandil Attenuates LPS-Induced Acute Lung Injury by Pulmonary Endothelial Cell Protection via NF-B and MAPK Pathways
Q39024659Nicotinamide adenine dinucleotide phosphate oxidase is differentially regulated in normal myometrium versus leiomyoma
Q35945695Nitric Oxide and Reactive Oxygen Species Coordinately Regulate the Germination of Puccinia striiformis f. sp. tritici Urediniospores
Q33854259No cancer predisposition or increased spontaneous mutation frequencies in NEIL DNA glycosylases-deficient mice
Q42292783Non-photonic sensing of membrane-delimited reactive species with a Na+ channel protein containing selenocysteine
Q35855299Nonphagocytic oxidase 1 causes death in lung epithelial cells via a TNF-RI-JNK signaling axis
Q38851856Novel insights into redox system and the mechanism of redox regulation
Q24316184Novel p47(phox)-related organizers regulate localized NADPH oxidase 1 (Nox1) activity
Q37643848Novel role for the yceGH tellurite resistance genes in the pathogenesis of Bacillus anthracis
Q33649852Novel role of NADPH oxidase in angiogenesis and stem/progenitor cell function.
Q54341815Novel role of NADPH oxidase in ischemic myocardium: a study with Nox2 knockout mice.
Q28282472Nox enzymes and oxidative stress in the immunopathology of the gastrointestinal tract
Q37852399Nox enzymes in allergic airway inflammation
Q36008117Nox regulation of smooth muscle contraction
Q37575857Nox-derived ROS are acutely activated in pressure overload pulmonary hypertension: indications for a seminal role for mitochondrial Nox4
Q39983260Nox-generated ROS modulate glucose uptake in a leukaemic cell line
Q37173872Nox1 is over-expressed in human colon cancers and correlates with activating mutations in K-Ras.
Q40145596Nox1 redox signaling mediates oncogenic Ras-induced disruption of stress fibers and focal adhesions by down-regulating Rho.
Q24320021Nox1-dependent reactive oxygen generation is regulated by Rac1
Q24300861Nox1-dependent superoxide production controls colon adenocarcinoma cell migration
Q34233390Nox2 and Rac1 regulate H2O2-dependent recruitment of TRAF6 to endosomal interleukin-1 receptor complexes
Q42016966Nox2 contributes to hyperinsulinemia-induced redox imbalance and impaired vascular function.
Q34577042Nox2 is required for macrophage chemotaxis towards CSF-1.
Q34504631Nox2 redox signaling maintains essential cell populations in the brain
Q41268543Nox2 regulates endothelial cell cycle arrest and apoptosis via p21cip1 and p53
Q33795974Nox4 B-loop creates an interface between the transmembrane and dehydrogenase domains
Q35038777Nox4 regulates Nrf2 and glutathione redox in cardiomyocytes in vivo.
Q35213232Nox4: a hydrogen peroxide-generating oxygen sensor
Q42173596Nox5 forms a functional oligomer mediated by self-association of its dehydrogenase domain
Q46654883NoxA activation by the small GTPase RacA is required to maintain a mutualistic symbiotic association between Epichloë festucae and perennial ryegrass
Q38291316Oncogenic Ras upregulates NADPH oxidase 1 gene expression through MEK-ERK-dependent phosphorylation of GATA-6.
Q33867129Opportunistic Pathogen Porphyromonas gingivalis Modulates Danger Signal ATP-Mediated Antibacterial NOX2 Pathways in Primary Epithelial Cells
Q37978891Opportunity nox: the future of NADPH oxidases as therapeutic targets in cardiovascular disease.
Q36403589Opposing actions of heat shock protein 90 and 70 regulate nicotinamide adenine dinucleotide phosphate oxidase stability and reactive oxygen species production.
Q35919447Oral Efficacy of Apigenin against Cutaneous Leishmaniasis: Involvement of Reactive Oxygen Species and Autophagy as a Mechanism of Action
Q90327010Oral Polymorphonuclear Neutrophil Contributes to Oral Health
Q33773394Organelle-targetable fluorescent probes for imaging hydrogen peroxide in living cells via SNAP-Tag protein labeling
Q35130226Oscillatory shear stress induces mitochondrial superoxide production: implication of NADPH oxidase and c-Jun NH2-terminal kinase signaling
Q37368617Ovarian dual oxidase (Duox) activity is essential for insect eggshell hardening and waterproofing
Q28383320Overcoming resistance to histone deacetylase inhibitors in human leukemia with the redox modulating compound β-phenylethyl isothiocyanate
Q37168354Oxidant sensing by reversible disulfide bond formation
Q38111712Oxidants and redox signaling in acute lung injury
Q33600452Oxidative Stress Resulting From Helicobacter pylori Infection Contributes to Gastric Carcinogenesis
Q60047016Oxidative Stress and Neonatal Respiratory Extracorporeal Membrane Oxygenation
Q38287176Oxidative Stress and Neurobiology of Demyelination
Q42067054Oxidative damage and carcinogenesis
Q36912559Oxidative damage pathways in relation to normal tissue injury
Q24657408Oxidative innate immune defenses by Nox/Duox family NADPH oxidases
Q37501271Oxidative stress and cardiovascular disease: novel tools give (free) radical insight
Q38702248Oxidative stress and chronic inflammation in osteoarthritis: can NRF2 counteract these partners in crime?
Q33904328Oxidative stress and hepatic Nox proteins in chronic hepatitis C and hepatocellular carcinoma
Q35008614Oxidative stress and redox modulation potential in type 1 diabetes.
Q36466847Oxidative stress and redox signalling in cardiac hypertrophy and heart failure.
Q37845832Oxidative stress and therapeutic opportunities: focus on the Ewing's sarcoma family of tumors
Q35910961Oxidative stress enzymes are required for DAF-16-mediated immunity due to generation of reactive oxygen species by Caenorhabditis elegans
Q36263651Oxidative stress in chronic venous leg ulcers
Q37820092Oxidative stress in early diabetic nephropathy: fueling the fire
Q48505452Oxidative stress in granulosa cells contributes to poor oocyte quality and IVF-ET outcomes in women with polycystic ovary syndrome.
Q37382855Oxidative stress in prostate cancer
Q34807521Oxidative stress mediates nephropathy in type Ia glycogen storage disease.
Q91206405Oxidative stress pathway gene transcription after bovine respiratory syncytial virus infection in vitro and ex vivo
Q42123491Oxidative stress signaling to chromatin in health and disease.
Q36909835Oxidative stress, DNA damage and repair in heart failure patients after implantation of continuous flow left ventricular assist devices
Q38343283Oxidative stress, NADPH oxidases, and arteries
Q38019997Oxidative stress, Noxs, and hypertension: experimental evidence and clinical controversies
Q37291314Oxidative stress, free radicals and bone remodeling
Q24635310Oxidative stress, mitochondrial dysfunction, and aging
Q37558095Oxidized CaMKII promotes asthma through the activation of mast cells
Q46863979Oxidized HDL induces cytotoxic effects: implications for atherogenic mechanism
Q43080066Oxygen in the evolution of complex life and the price we pay.
Q41888445Oxygen radicals elicit paralysis and collapse of spinal cord neuron growth cones upon exposure to proinflammatory cytokines
Q33530454Oxygen-sensitive outcomes and gene expression in acute ischemic stroke
Q91970520PERK-Mediated Unfolded Protein Response Activation and Oxidative Stress in PARK20 Fibroblasts
Q24296651PI3K delta and PI3K gamma: partners in crime in inflammation in rheumatoid arthritis and beyond?
Q37138890PKCδ mediates paraquat-induced Nox1 expression in dopaminergic neurons
Q41602372PKR activation causes inflammation and MMP-13 secretion in human degenerated articular chondrocytes
Q41669447PPARα regulates endothelial progenitor cell maturation and myeloid lineage differentiation through a NADPH oxidase-dependent mechanism in mice
Q35964957PVN adenovirus-siRNA injections silencing either NOX2 or NOX4 attenuate aldosterone/NaCl-induced hypertension in mice
Q31108078Paleomycology of the Princeton Chert. III. Dictyosporic microfungi, Monodictysporites princetonensis gen. et sp. nov., associated with decayed rhizomes of an Eocene semi-aquatic fern
Q39348472Paradoxical roles of dual oxidases in cancer biology.
Q35142907Paraquat-induced reactive oxygen species inhibit neutrophil apoptosis via a p38 MAPK/NF-κB-IL-6/TNF-α positive-feedback circuit
Q46908142Parasitic worms stimulate host NADPH oxidases to produce reactive oxygen species that limit plant cell death and promote infection
Q59808511Park 7: A Novel Therapeutic Target for Macrophages in Sepsis-Induced Immunosuppression
Q28592872Park7 interacts with p47(phox) to direct NADPH oxidase-dependent ROS production and protect against sepsis
Q21296719Pathogen recognition and activation of the innate immune response in zebrafish
Q33755215Pathogenesis of Afa/Dr diffusely adhering Escherichia coli
Q36870107Pathological investigation of oxidative stress in the post-genomic era.
Q38384633Pathophysiological implications of mitochondrial oxidative stress mediated by mitochondriotropic agents and polyamines: the role of tyrosine phosphorylation.
Q34139377Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis
Q37925062Peptidoglycan: a critical activator of the mammalian immune system during infection and homeostasis
Q37162500Peroxide generation by p47phox-Src activation of Nox2 has a key role in protein kinase C-induced arterial smooth muscle contraction
Q35762914Peroxiredoxin functions as a peroxidase and a regulator and sensor of local peroxides
Q38708374Peroxiredoxin-6 Negatively Regulates Bactericidal Activity and NF-κB Activity by Interrupting TRAF6-ECSIT Complex
Q35548410Peroxiredoxin-controlled G-CSF signalling at the endoplasmic reticulum-early endosome interface
Q65002704Peroxisomes and Oxidative Stress: Their Implications in the Modulation of Cellular Immunity During Mycobacterial Infection.
Q37161242Persistence of the bacterial pathogen Granulibacter bethesdensis in chronic granulomatous disease monocytes and macrophages lacking a functional NADPH oxidase
Q36627802Phagocytosis-coupled activation of the superoxide-producing phagocyte oxidase, a member of the NADPH oxidase (nox) family
Q37972825Pharmacologic strategies to target oxidative stress in heart failure
Q36429323Pharmacological inhibition of TLR4-NOX4 signal protects against neuronal death in transient focal ischemia
Q60949517Pharmacological stimulation of NQO1 decreases NADPH levels and ameliorates acute pancreatitis in mice
Q36914306Phosphatidylinositol (4,5)-bisphosphate modulates Nox5 localization via an N-terminal polybasic region
Q89965850Phosphoinositide 3-Kinase Promotes Oxidative Burst, Stomatal Closure and Plant Immunity in Bacterial Invasion
Q37261114Phosphorylation of Nox1 regulates association with NoxA1 activation domain.
Q24318670Phosphorylation of Noxo1 at threonine 341 regulates its interaction with Noxa1 and the superoxide-producing activity of Nox1
Q28266171Phosphorylation of p22phox on threonine 147 enhances NADPH oxidase activity by promoting p47phox binding
Q42834223Phosphorylation of serine-504 of tNOX (ENOX2) modulates cell proliferation and migration in cancer cells
Q39334949Phox activity of differentiated PLB-985 cells is enhanced, in an agonist specific manner, by the PLA2 activity of Prdx6-PLA2.
Q34193079Physiological mechanisms of vascular response induced by shear stress and effect of exercise in systemic and placental circulation
Q39129264Physiological roles of macrophages
Q36497800Pivotal role of reactive oxygen species in differential regulation of lipopolysaccharide-induced prostaglandins production in macrophages
Q39088167Plant-parasitic nematodes: towards understanding molecular players in stress responses
Q42787229Plasma membrane electron transport in pancreatic β-cells is mediated in part by NQO1.
Q37071700Platelet receptor redox regulation
Q34430784Point mutations in the proline-rich region of p22phox are dominant inhibitors of Nox1- and Nox2-dependent reactive oxygen generation.
Q34582811Polarity proteins Bem1 and Cdc24 are components of the filamentous fungal NADPH oxidase complex
Q39511359Polymeric proanthocyanidins from Sicilian pistachio (Pistacia vera L.) nut extract inhibit lipopolysaccharide-induced inflammatory response in RAW 264.7 cells
Q41081215Polymorphisms in NADPH oxidase CYBA gene modify the risk of ESRD in patients with chronic glomerulonephritis
Q42414902Polyunsaturated fatty acids modulate NOX 4 anion superoxide production in human fibroblasts
Q35529695Post-treatment with an ultra-low dose of NADPH oxidase inhibitor diphenyleneiodonium attenuates disease progression in multiple Parkinson's disease models
Q37262829Postconditioning ameliorates mitochondrial DNA damage and deletion after renal ischemic injury
Q28818673Potential implication of the chemical properties and bioactivity of nitrone spin traps for therapeutics
Q30365807Potential role of NADPH oxidase in pathogenesis of pancreatitis.
Q33761401Potentiation of epithelial innate host responses by intercellular communication
Q33895555Preparation and use of MitoPY1 for imaging hydrogen peroxide in mitochondria of live cells
Q37184946Prevention of TNF-induced necrotic cell death by rottlerin through a Nox1 NADPH oxidase
Q90628019Primary immunodeficiencies reveal the essential role of tissue neutrophils in periodontitis
Q36138498Primary involvement of NADPH oxidase 4 in hypoxia-induced generation of reactive oxygen species in adipose-derived stem cells
Q62030472Pro-metastatic signaling by c-Met through RAC-1 and reactive oxygen species (ROS)
Q40144800Probing the redox activity of T-lymphocytes deposited at electrode surfaces with voltammetric methods.
Q33356419Process of aerenchyma formation and reactive oxygen species induced by waterlogging in wheat seminal roots
Q39419866Production of reactive oxygen species by plant NADPH oxidases.
Q37854112Production of reactive oxygen species is turned on and rapidly shut down in epithelial cells infected with Chlamydia trachomatis
Q34044165Programmed cell death and its role in inflammation
Q37219375Proinflammatory cytokines provoke oxidative damage to actin in neuronal cells mediated by Rac1 and NADPH oxidase
Q33942155Prolonged fasting does not increase oxidative damage or inflammation in postweaned northern elephant seal pups
Q36448748Prolonged production of reactive oxygen species in response to B cell receptor stimulation promotes B cell activation and proliferation
Q38502092Prolonged survival of islet allografts in mice treated with rosmarinic acid and anti-CD154 antibody.
Q38945448Propofol attenuates lipopolysaccharide-induced reactive oxygen species production through activation of Nrf2/GSH and suppression of NADPH oxidase in human alveolar epithelial cells
Q90578675Protective Effect of Selenium-L-methionine on Radiation-induced Acute Pneumonitis and Lung Fibrosis in Rat
Q35181125Protective effect of suberoylanilide hydroxamic acid against lipopolysaccharide-induced liver damage in rodents
Q37301766Protective effects of alpha lipoic acid on radiation-induced salivary gland injury in rats
Q34764076Protective effects of andrographolide analogue AL-1 on ROS-induced RIN-mβ cell death by inducing ROS generation.
Q33553407Protective role of Cys-178 against the inactivation and oligomerization of human insulin-degrading enzyme by oxidation and nitrosylation
Q41861138Protective role of Osthole on myocardial cell apoptosis induced by doxorubicin in rats
Q27005875Protein disulfide isomerase and host-pathogen interaction
Q39250599Protein disulfide isomerase in ALS mouse glia links protein misfolding with NADPH oxidase-catalyzed superoxide production
Q35171206Protein quality control under oxidative stress conditions
Q29614826Protein tyrosine phosphatases: from genes, to function, to disease
Q60049122Proteomics analysis of chicken peripheral blood lymphocyte in Taishan Pinus massoniana pollen polysaccharide regulation
Q90308514Proton leak regulates mitochondrial reactive oxygen species generation in endothelial cell activation and inflammation - A novel concept
Q37000667Pulmonary neuroendocrine cell system in pediatric lung disease-recent advances
Q57291683Quantitative phosphoproteomic analysis reveals common regulatory mechanisms between effector- and PAMP-triggered immunity in plants
Q89019519Quercetin manipulates the expression of genes involved in the reactive oxygen species (ROS) process in chicken heterophils
Q89454752RNA Profiling Analysis of the Serum Exosomes Derived from Patients with Chronic Hepatitis and Acute-on-chronic Liver Failure Caused By HBV
Q26753142ROS and ROS-Mediated Cellular Signaling
Q29615229ROS function in redox signaling and oxidative stress
Q28075971ROS homeostasis and metabolism: a dangerous liason in cancer cells
Q41047666ROS induced distribution of mitochondria to filopodia by Myo19 depends on a class specific tryptophan in the motor domain.
Q37716710ROS mediates interferon gamma induced phosphorylation of Src, through the Raf/ERK pathway, in MCF-7 human breast cancer cell line
Q34516835ROS production is essential for the apoptotic function of E2F1 in pheochromocytoma and neuroblastoma cell lines
Q38193013ROS signalling between endothelial cells and cardiac cells
Q28396460ROS, Notch, and Wnt signaling pathways: crosstalk between three major regulators of cardiovascular biology
Q38746515ROS-activated calcium signaling mechanisms regulating endothelial barrier function
Q33409045ROS-mediated platelet generation: a microenvironment-dependent manner for megakaryocyte proliferation, differentiation, and maturation
Q37723678ROS: Crucial Intermediators in the Pathogenesis of Intervertebral Disc Degeneration
Q91259739RUNX3 enhances TRAIL-induced apoptosis by upregulating DR5 in colorectal cancer
Q30491699Rac1 modulates stimulus-evoked Ca(2+) release in neuronal growth cones via parallel effects on microtubule/endoplasmic reticulum dynamics and reactive oxygen species production
Q40349340Rac1-NADPH oxidase-regulated generation of reactive oxygen species mediates glutamate-induced apoptosis in SH-SY5Y human neuroblastoma cells
Q33784145Rac1-mediated NADPH oxidase release of O2- regulates epithelial sodium channel activity in the alveolar epithelium
Q36287875Radical medicine: treating ageing to cure disease
Q36955833Radical-free biology of oxidative stress
Q37392264Ras and Nox: Linked signaling networks?
Q42609911Rational design of small molecule inhibitors targeting the Rac GTPase-p67(phox) signaling axis in inflammation.
Q24300000Reactivation of oxidized PTP1B and PTEN by thioredoxin 1
Q38763976Reactive Oxygen Species Derived from NOX3 and NOX5 Drive Differentiation of Human Oligodendrocytes
Q26740114Reactive Oxygen Species Regulate T Cell Immune Response in the Tumor Microenvironment
Q46288731Reactive Oxygen Species Regulate the Inflammatory Function of NKT Cells through Promyelocytic Leukemia Zinc Finger.
Q61810421Reactive Oxygen Species Related Noncoding RNAs as Regulators of Cardiovascular Diseases
Q35769230Reactive Oxygen Species in Planarian Regeneration: An Upstream Necessity for Correct Patterning and Brain Formation.
Q28070007Reactive Oxygen Species: Physiological and Physiopathological Effects on Synaptic Plasticity
Q39539209Reactive oxygen generated by NADPH oxidase 1 (Nox1) contributes to cell invasion by regulating matrix metalloprotease-9 production and cell migration.
Q28384349Reactive oxygen production induced by the gut microbiota: pharmacotherapeutic implications
Q37135987Reactive oxygen species and angiogenesis: NADPH oxidase as target for cancer therapy
Q37924981Reactive oxygen species and endothelial function--role of nitric oxide synthase uncoupling and Nox family nicotinamide adenine dinucleotide phosphate oxidases
Q34939523Reactive oxygen species and the brain in sleep apnea
Q36848849Reactive oxygen species and the cardiovascular system
Q53263574Reactive oxygen species are related to ionic fluxes and volume decrease in apoptotic cerebellar granule neurons: role of NOX enzymes.
Q46361361Reactive oxygen species derived from NOX1/NADPH oxidase enhance inflammatory pain.
Q35963391Reactive oxygen species derived from Nox4 mediate BMP2 gene transcription and osteoblast differentiation.
Q41870703Reactive oxygen species exert opposite effects on Tyr23 phosphorylation of the nuclear and cortical pools of annexin A2
Q34401141Reactive oxygen species generated by NADPH oxidase 2 and 4 are required for chondrogenic differentiation.
Q37774919Reactive oxygen species in TNFalpha-induced signaling and cell death.
Q28396273Reactive oxygen species in inflammation and tissue injury
Q36801016Reactive oxygen species in phagocytic leukocytes
Q38101671Reactive oxygen species in the immune system
Q36674343Reactive oxygen species in the neuropathogenesis of hypertension
Q34805998Reactive oxygen species in the regulation of synaptic plasticity and memory
Q36337991Reactive oxygen species mediate crosstalk between NF-kappaB and JNK.
Q33713850Reactive oxygen species mediate lysophosphatidic acid induced signaling in ovarian cancer cells.
Q48491878Reactive oxygen species mediate the potentiating effects of ATP on GABAergic synaptic transmission in the immature hippocampus.
Q24542382Reactive oxygen species play a role in regulating a fungus-perennial ryegrass mutualistic interaction
Q38841868Reactive oxygen species production has a critical role in hypoxia-induced Stat3 activation and angiogenesis in human glioblastoma
Q43275808Reactive oxygen species promote angiogenesis in the infarcted rat heart
Q38206835Reactive oxygen species regulate hematopoietic stem cell self-renewal, migration and development, as well as their bone marrow microenvironment
Q34241660Reactive oxygen species regulate the levels of dual oxidase (Duox1-2) in human neuroblastoma cells
Q57748274Reactive oxygen species signaling in response to pathogens
Q23914964Reactive oxygen species-activated Akt/ASK1/p38 signaling pathway in nickel compound-induced apoptosis in BEAS 2B cells
Q37560671Reactive oxygen species-dependent signaling regulates cancer
Q34777807Real-time imaging of the intracellular glutathione redox potential.
Q46343029Recent Developments in the Probes and Assays for Measurement of the Activity of NADPH Oxidases.
Q36122073Recent developments in detection of superoxide radical anion and hydrogen peroxide: Opportunities, challenges, and implications in redox signaling.
Q46845199Recognition of apoptotic cells by macrophages activates the peroxisome proliferator-activated receptor-gamma and attenuates the oxidative burst.
Q29615709Reconciling the chemistry and biology of reactive oxygen species
Q46256827Redox Control of Vascular Function
Q36283203Redox Proteomics and Platelet Activation: Understanding the Redox Proteome to Improve Platelet Quality for Transfusion
Q46280851Redox Signaling and Persistent Pulmonary Hypertension of the Newborn
Q38688126Redox Signaling in Neurotransmission and Cognition During Aging
Q57065952Redox Signaling of NADPH Oxidases Regulates Oxidative Stress Responses, Immunity and Aging
Q92865063Redox Systems Biology of Nutrition and Oxidative Stress
Q37124872Redox amplification of apoptosis by caspase-dependent cleavage of glutaredoxin 1 and S-glutathionylation of Fas.
Q35068102Redox and nitric oxide-mediated regulation of sensory neuron ion channel function
Q38155452Redox balance and cardioprotection.
Q22299216Redox biology and gastric carcinogenesis: the role of Helicobacter pylori
Q34642404Redox compartmentalization and cellular stress
Q33742737Redox modifier genes and pathways in amyotrophic lateral sclerosis
Q35987578Redox modifier genes in amyotrophic lateral sclerosis in mice.
Q34623471Redox paradox: insulin action is facilitated by insulin-stimulated reactive oxygen species with multiple potential signaling targets
Q30367032Redox proteomics analysis to decipher the neurobiology of Alzheimer-like neurodegeneration: overlaps in Down's syndrome and Alzheimer's disease brain.
Q38618081Redox proteomics: Methods for the identification and enrichment of redox-modified proteins and their applications
Q34561980Redox regulation by Keap1 and Nrf2 controls intestinal stem cell proliferation in Drosophila
Q36476273Redox regulation of epidermal growth factor receptor signaling through cysteine oxidation
Q39256530Redox regulation of gasotransmission in the vascular system: A focus on angiogenesis
Q37073431Redox regulation of interleukin-4 signaling
Q34251097Redox regulation of lipopolysaccharide-mediated sulfiredoxin induction, which depends on both AP-1 and Nrf2.
Q35174581Redox regulation of protein kinases
Q33616624Redox regulation of protein tyrosine phosphatase 1B by peroxymonophosphate (=O3POOH)
Q39174495Redox regulation of the actin cytoskeleton and its role in the vascular system
Q36642721Redox regulation of the hypoxia-inducible factor
Q40037775Redox regulation of the protein tyrosine phosphatase PTP1B in cancer cells.
Q38997406Redox regulation of transient receptor potential channels in the endothelium
Q35738096Redox signaling at invasive microdomains in cancer cells.
Q34629326Redox signaling in cardiac myocytes.
Q37446110Redox signaling in cardiovascular health and disease.
Q28071377Redox signaling in cardiovascular pathophysiology: A focus on hydrogen peroxide and vascular smooth muscle cells
Q34928547Redox signaling mediated by the gut microbiota
Q33779267Redox signaling mediates symbiosis between the gut microbiota and the intestine.
Q24657425Redox warfare between airway epithelial cells and Pseudomonas: dual oxidase versus pyocyanin
Q36756386Redox-based regulation of signal transduction: principles, pitfalls, and promises
Q38160013Redox-sensitive probes for the measurement of redox chemistries within phagosomes of macrophages and dendritic cells
Q46896337Reduced expression of GSTM2 and increased oxidative stress in spontaneously hypertensive rat.
Q47215081Reduction-oxidation (redox) system in radiation-induced normal tissue injury: molecular mechanisms and implications in radiation therapeutics.
Q43408050Reductive Stress in Inflammation-Associated Diseases and the Pro-Oxidant Effect of Antioxidant Agents
Q35925959Regulation of NAD(P)H oxidases by AMPK in cardiovascular systems
Q38109629Regulation of NF-κB-induced inflammatory signaling by lipid peroxidation-derived aldehydes
Q30156868Regulation of NOXO1 activity through reversible interactions with p22 and NOXA1.
Q36865824Regulation of Nox and Duox enzymatic activity and expression
Q30277764Regulation of Rac1 and Reactive Oxygen Species Production in Response to Infection of Gastrointestinal Epithelia
Q36837015Regulation of apical dominance in Aspergillus nidulans hyphae by reactive oxygen species
Q37780586Regulation of apoptosis through cysteine oxidation: implications for fibrotic lung disease.
Q26781628Regulation of cytoskeletal dynamics by redox signaling and oxidative stress: implications for neuronal development and trafficking
Q44932599Regulation of insulin signaling through reversible oxidation of the protein-tyrosine phosphatases TC45 and PTP1B.
Q24548975Regulation of late G1/S phase transition and APC Cdh1 by reactive oxygen species
Q37826870Regulation of myocardial growth and death by NADPH oxidase
Q36627810Regulation of neutrophil functions by proinflammatory cytokines
Q36253505Regulation of protein kinase CK1alphaLS by dephosphorylation in response to hydrogen peroxide
Q46835264Regulation of rice NADPH oxidase by binding of Rac GTPase to its N-terminal extension
Q36666637Regulation of smooth muscle by inducible nitric oxide synthase and NADPH oxidase in vascular proliferative diseases
Q46940007Regulation of superoxide-producing NADPH oxidases in nonphagocytic cells
Q36516270Regulation of swelling-activated Cl(-) current by angiotensin II signalling and NADPH oxidase in rabbit ventricle
Q38459105Regulation of the NADPH Oxidase RBOHD During Plant Immunity.
Q37139780Regulation of the phagocyte NADPH oxidase activity: phosphorylation of gp91phox/NOX2 by protein kinase C enhances its diaphorase activity and binding to Rac2, p67phox, and p47phox
Q48103763Regulatory Mechanisms and Novel Therapeutic Targeting Strategies for Protein Tyrosine Phosphatases.
Q35165294Relationship of electrophilic stress to aging
Q39582732Relative contributions of mitochondria and NADPH oxidase to deoxycorticosterone acetate-salt hypertension in mice
Q33879330Reperfusion and neurovascular dysfunction in stroke: from basic mechanisms to potential strategies for neuroprotection
Q40131334Repression of sestrin family genes contributes to oncogenic Ras-induced reactive oxygen species up-regulation and genetic instability
Q35192591Requirement of FADD, NEMO, and BAX/BAK for aberrant mitochondrial function in tumor necrosis factor alpha-induced necrosis
Q46796816Requirement of reactive oxygen species-dependent activation of ASK1-p38 MAPK pathway for extracellular ATP-induced apoptosis in macrophage.
Q46245607Respiratory Burst Oxidase Homolog Gene A Is Crucial for Rhizobium Infection and Nodule Maturation and Function in Common Bean.
Q36444085Respiratory syncytial virus infection: mechanisms of redox control and novel therapeutic opportunities
Q34915546Response of rat lung tissue to short-term hyperoxia: a proteomic approach
Q38794054Resveratrol Protects against Titanium Particle-Induced Aseptic Loosening Through Reduction of Oxidative Stress and Inactivation of NF-κB.
Q37572374Rethinking antioxidants in the intensive care unit
Q36737013Reversible inactivation of deubiquitinases by reactive oxygen species in vitro and in cells.
Q37693081Reversible oxidation and inactivation of the tumor suppressor PTEN in cells stimulated with peptide growth factors
Q37349116Rheumatologic and autoimmune manifestations of primary immunodeficiency disorders
Q35524948Rhinovirus infection liberates planktonic bacteria from biofilm and increases chemokine responses in cystic fibrosis airway epithelial cells
Q35931392Rho Kinase ROCK2 Mediates Acid-Induced NADPH Oxidase NOX5-S Expression in Human Esophageal Adenocarcinoma Cells
Q24318509Riboflavin kinase couples TNF receptor 1 to NADPH oxidase
Q90290842Ribonucleotide Reductase Inhibitor 3-AP Induces Oncogenic Virus Infected Cell Death and Represses Tumor Growth
Q39140136Robust T cell responses to aspergillosis in chronic granulomatous disease: implications for immunotherapy
Q38188356Role of 8-nitro-cGMP and its redox regulation in cardiovascular electrophilic signaling.
Q55517008Role of Angiotensin II type 1 receptor on renal NAD(P)H oxidase, oxidative stress and inflammation in nitric oxide inhibition induced-hypertension.
Q26825386Role of DUOX in gut inflammation: lessons from Drosophila model of gut-microbiota interactions
Q37445914Role of NADPH oxidase in atherosclerosis
Q46797946Role of NADPH oxidase in the regulation of autophagy in cardiomyocytes.
Q33632736Role of NADPH oxidases in liver fibrosis
Q26800143Role of NADPH oxidases in the redox biology of liver fibrosis
Q38072297Role of Rac1-mineralocorticoid-receptor signalling in renal and cardiac disease
Q39772570Role of a novel bile acid receptor TGR5 in the development of oesophageal adenocarcinoma
Q42487391Role of endothelial Nox2 NADPH oxidase in angiotensin II-induced hypertension and vasomotor dysfunction
Q27026361Role of microglia in oxidative toxicity associated with encephalomycarditis virus infection in the central nervous system
Q36952975Role of oxidant stress on AT1 receptor expression in neurons of rabbits with heart failure and in cultured neurons
Q35911112Role of oxidative stress and inflammation in the origin of Type 2 diabetes--a paradigm shift
Q43061685Role of the NADPH oxidase systems Nox and Duox in host defense and inflammation
Q38487545Roles of NADPH oxidases in cisplatin-induced reactive oxygen species generation and ototoxicity.
Q92854305Roles of Toll-Like Receptors in Nitroxidative Stress in Mammals
Q40387269Rosmarinic acid inhibits the formation of reactive oxygen and nitrogen species in RAW264.7 macrophages
Q33851205Rutaecarpine prevents hypoxia-reoxygenation-induced myocardial cell apoptosis via inhibition of NADPH oxidases
Q57471957S-nitrosylation of the zinc finger protein SRG1 regulates plant immunity
Q64239542SHMT1 inhibits the metastasis of HCC by repressing NOX1-mediated ROS production
Q35917608SLAM is a microbial sensor that regulates bacterial phagosome functions in macrophages.
Q24307703SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model
Q40065679STAT5 mediates PAF-induced NADPH oxidase NOX5-S expression in Barrett's esophageal adenocarcinoma cells
Q38195791STEAP4 and insulin resistance
Q38139897SUMO: a (oxidative) stressed protein.
Q36522036SUMO: regulating the regulator.
Q39732197Selective ascorbate toxicity in malignant mesothelioma: a redox Trojan mechanism
Q36121107Selective killing of K-ras-transformed pancreatic cancer cells by targeting NAD(P)H oxidase.
Q36321026Selective role for superoxide in InsP3 receptor-mediated mitochondrial dysfunction and endothelial apoptosis
Q92740202Self-assembled single-atom nanozyme for enhanced photodynamic therapy treatment of tumor
Q61444256Sensitive Molybdenum Disulfide Based Field Effect Transistor Sensor for Real-time Monitoring of Hydrogen Peroxide
Q36321530Serum levels of nicotinamide-adenine dinucleotide phosphate oxidase 4 are associated with non-valvular atrial fibrillation
Q34660270Several dual specificity phosphatases coordinate to control the magnitude and duration of JNK activation in signaling response to oxidative stress
Q28818656Several steps of lateral gene transfer followed by events of 'birth-and-death' evolution shaped a fungal sorbicillinoid biosynthetic gene cluster
Q41232705Severity of pancreatitis‑associated intestinal mucosal barrier injury is reduced following treatment with the NADPH oxidase inhibitor apocynin
Q33295021Sex hormones induce direct epithelial and inflammation-mediated oxidative/nitrosative stress that favors prostatic carcinogenesis in the noble rat.
Q30493800Signaling components of redox active endosomes: the redoxosomes.
Q35265620Signaling in H2O2-induced increase in cell proliferation in Barrett's esophageal adenocarcinoma cells
Q35492103Significance of marrow-derived nicotinamide adenine dinucleotide phosphate oxidase in experimental ischemic stroke.
Q38739788Silencer-of-Death Domain Mediates Acid-Induced Decrease in Cell Apoptosis in Barrett's Associated Esophageal Adenocarcinoma Cells
Q33921217Silencing nox4 in the paraventricular nucleus improves myocardial infarction-induced cardiac dysfunction by attenuating sympathoexcitation and periinfarct apoptosis
Q46060004Similar and distinct roles of NADPH oxidase components in the tangerine pathotype of Alternaria alternata.
Q39418532Similarities and Distinctions of Cancer and Immune Metabolism in Inflammation and Tumors
Q54976937Simvastatin Inhibits Activation of NADPH Oxidase/p38 MAPK Pathway and Enhances Expression of Antioxidant Protein in Parkinson Disease Models.
Q33500606Single europium-doped nanoparticles measure temporal pattern of reactive oxygen species production inside cells.
Q38171825Singlet oxygen generation by cyclometalated complexes and applications
Q37492539Skin Aging-Dependent Activation of the PI3K Signaling Pathway via Downregulation of PTEN Increases Intracellular ROS in Human Dermal Fibroblasts
Q37700389Sleep fragmentation in mice induces nicotinamide adenine dinucleotide phosphate oxidase 2-dependent mobilization, proliferation, and differentiation of adipocyte progenitors in visceral white adipose tissue
Q35683048Sleep fragmentation induces cognitive deficits via nicotinamide adenine dinucleotide phosphate oxidase-dependent pathways in mouse
Q37534342Sleep fragmentation promotes NADPH oxidase 2-mediated adipose tissue inflammation leading to insulin resistance in mice.
Q36887547Small-molecule therapies for cardiac hypertrophy: moving beneath the cell surface
Q33851056Sodium channels as gateable non-photonic sensors for membrane-delimited reactive species
Q37290035Sodium tanshinone IIA sulfonate attenuates angiotensin II-induced collagen type I expression in cardiac fibroblasts in vitro
Q90252484Sordaria macrospora: 25 years as a model organism for studying the molecular mechanisms of fruiting body development
Q58075704Sources of Vascular Nitric Oxide and Reactive Oxygen Species and Their Regulation
Q89487190Spatial Properties of Reactive Oxygen Species Govern Pathogen-Specific Immune System Responses
Q36118494Specificity in reactive oxidant signaling: think globally, act locally
Q42906092Spironolactone inhibits NADPH oxidase-induced oxidative stress and enhances eNOS in human endothelial cells
Q35035200Spontaneous and aging-dependent development of arthritis in NADPH oxidase 2 deficiency through altered differentiation of CD11b+ and Th/Treg cells
Q42154398Spring brings breezes, wheezes, and pollen oxidases
Q40355989Src homology 2-containing phosphotyrosine phosphatase regulates endothelin-1-induced epidermal growth factor receptor transactivation in rat renal tubular cell NRK-52E.
Q42574533Stem cells and oxidants: too little of a bad thing
Q93186037Stimulation of P2X7 Enhances Whole Body Energy Metabolism in Mice
Q40266375Stimulation of the alveolar macrophage respiratory burst by ADP causes selective glutathionylation of protein tyrosine phosphatase 1B.
Q26853670Stop the flow: a paradigm for cell signaling mediated by reactive oxygen species in the pulmonary endothelium
Q36642035Strategy for dual-analyte luciferin imaging: in vivo bioluminescence detection of hydrogen peroxide and caspase activity in a murine model of acute inflammation
Q38166370Stress Response and Pathogenicity of the Necrotrophic Fungal Pathogen Alternaria alternata
Q28282131Structure, regulation and evolution of Nox-family NADPH oxidases that produce reactive oxygen species
Q39031828Subcellular Redox Targeting: Bridging in Vitro and in Vivo Chemical Biology.
Q35792499Subcellular localization and function of alternatively spliced Noxo1 isoforms
Q28564951Subcellular localization of nicotinamide adenine dinucleotide phosphate oxidase subunits in neurons and astroglia of the rat medial nucleus tractus solitarius: relationship with tyrosine hydroxylase immunoreactive neurons
Q34381164Subpicomolar diphenyleneiodonium inhibits microglial NADPH oxidase with high specificity and shows great potential as a therapeutic agent for neurodegenerative diseases
Q29011150Sulfenic acid chemistry, detection and cellular lifetime
Q58788620Sulforaphane protects rabbit corneas against oxidative stress injury in keratoconus through activation of the Nrf-2/HO-1 antioxidant pathway
Q36999104Superoxide and derived reactive oxygen species in the regulation of hypoxia-inducible factors.
Q37792074Superoxide anion and hydrogen peroxide-induced signaling and damage in angiotensin II and aldosterone action
Q35810708Superoxide flux in endothelial cells via the chloride channel-3 mediates intracellular signaling
Q37370570Superoxide induces Neutrophil Extracellular Trap Formation in a TLR-4 and NOX-dependent mechanism
Q37264479Superoxide production by NAD(P)H oxidase and mitochondria is increased in genetically obese and hyperglycemic rat heart and aorta before the development of cardiac dysfunction. The role of glucose-6-phosphate dehydrogenase-derived NADPH.
Q38411556Superoxide serves as a putative signal molecule for plant cell division: overexpression of CaRLK1 promotes the plant cell cycle via accumulation of O2- and decrease in H2 O2.
Q33751396Suppression of ROS generation by 4,4-diaminodiphenylsulfone in non-phagocytic human diploid fibroblasts
Q40196823Suppression of microglial inflammatory activity by myelin phagocytosis: role of p47-PHOX-mediated generation of reactive oxygen species.
Q33315751Survival signaling by C-RAF: mitochondrial reactive oxygen species and Ca2+ are critical targets
Q37352682Symbiotic lactobacilli stimulate gut epithelial proliferation via Nox-mediated generation of reactive oxygen species
Q36051340Synaptic localization of a functional NADPH oxidase in the mouse hippocampus
Q28573824Synergistic activation of glucose-6-phosphate dehydrogenase and NAD(P)H oxidase by Src kinase elevates superoxide in type 2 diabetic, Zucker fa/fa, rat liver
Q90264061Synthesis and Evaluations of Novel Apocynin Derivatives as Anti-Glioma Agents
Q42196490Systems analysis of the role of bone morphogenic protein 4 in endothelial inflammation
Q26782669T cells and reactive oxygen species
Q28595069T cells express a phagocyte-type NADPH oxidase that is activated after T cell receptor stimulation
Q41487705TAT-mediated transduction of bacterial redox proteins generates a cytoprotective effect on neuronal cells
Q34544398TCR-triggered extracellular superoxide production is not required for T-cell activation.
Q89819646TGF-β3 Induces Autophagic Activity by Increasing ROS Generation in a NOX4-Dependent Pathway
Q33584615TLR Cross-Talk Mechanism of Hemorrhagic Shock-Primed Pulmonary Neutrophil Infiltration
Q34180844TLR signalling augments macrophage bactericidal activity through mitochondrial ROS.
Q47098726TLR4-NOX2 axis regulates the phagocytosis and killing of Mycobacterium tuberculosis by macrophages
Q36973962TNF-alpha upregulates the A2B adenosine receptor gene: The role of NAD(P)H oxidase 4.
Q38107792TNF-α signalling and inflammation: interactions between old acquaintances
Q37299479TNFR1 signaling kinetics: spatiotemporal control of three phases of IKK activation by posttranslational modification
Q37687495TNFR1/phox interaction and TNFR1 mitochondrial translocation Thwart silica-induced pulmonary fibrosis.
Q37095205TNFalpha and reactive oxygen species in necrotic cell death
Q93012264TNFα promotes mucosal wound repair through enhanced platelet activating factor receptor signaling in the epithelium
Q39037897TREM-2 promotes macrophage-mediated eradication of Pseudomonas aeruginosa via a PI3K/Akt pathway
Q24644998TRPM2-mediated Ca2+influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration
Q97644542TaRac6 Is a Potential Susceptibility Factor by Regulating the ROS Burst Negatively in the Wheat-Puccinia striiformis f. sp. tritici Interaction
Q46891641Tadpole tail regeneration in Xenopus
Q42701551Targeted Removal of Bioavailable Metal as a Detoxification Strategy for Carbon Nanotubes
Q28067161Targeting TRPM2 in ROS-Coupled Diseases
Q37145594Targeting cellular antioxidant enzymes for treating atherosclerotic vascular disease
Q37602866Targeting inflammation and oxidative stress in atrial fibrillation: role of 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibition with statins.
Q30409463Targeting xCT, a cystine-glutamate transporter induces apoptosis and tumor regression for KSHV/HIV-associated lymphoma
Q52641738Taurine protects dopaminergic neurons in a mouse Parkinson's disease model through inhibition of microglial M1 polarization.
Q64969685Taurine protects noradrenergic locus coeruleus neurons in a mouse Parkinson's disease model by inhibiting microglial M1 polarization
Q27331504Tetraspanin is required for generation of reactive oxygen species by the dual oxidase system in Caenorhabditis elegans
Q36282656Tetrazolium dyes as tools in cell biology: new insights into their cellular reduction.
Q40224958The ADP-stimulated NADPH oxidase activates the ASK-1/MKK4/JNK pathway in alveolar macrophages
Q91995791The Behavioral Sequelae of Social Defeat Require Microglia and Are Driven by Oxidative Stress in Mice
Q92620716The Bidirectional Interactions between Resveratrol and Gut Microbiota: An Insight into Oxidative Stress and Inflammatory Bowel Disease Therapy
Q34215404The CD14+CD16+ inflammatory monocyte subset displays increased mitochondrial activity and effector function during acute Plasmodium vivax malaria
Q64082882The DNA damage induced by the Cytosine Deaminase APOBEC3A Leads to the production of ROS
Q61799925The Emerging Role of Estrogens in Thyroid Redox Homeostasis and Carcinogenesis
Q90546431The Emerging Roles of Nicotinamide Adenine Dinucleotide Phosphate Oxidase 2 in Skeletal Muscle Redox Signaling and Metabolism
Q41660449The Future Challenge of Reactive Oxygen Species (ROS) in Hypertension: From Bench to Bed Side
Q28070162The Influence of the Gut Microbiota on Host Physiology: In Pursuit of Mechanisms
Q41934785The More Effective Treatment of Atrial Fibrillation Applying the Natural Compounds; as NADPH Oxidase and Ion Channel Inhibitors
Q38896484The NADPH oxidase NOX5 protects against apoptosis in ALK-positive anaplastic large-cell lymphoma cell lines
Q33213948The NADPH oxidase Nox3 constitutively produces superoxide in a p22phox-dependent manner: its regulation by oxidase organizers and activators
Q42017864The NADPH oxidase Nox4 and aging in the heart.
Q27315959The NADPH oxidase complexes in Botrytis cinerea: evidence for a close association with the ER and the tetraspanin Pls1
Q34047799The NADPH oxidases NOX4 and DUOX2 regulate cell cycle entry via a p53-dependent pathway
Q46172397The NOX Family of Proteins Is Also Present in Bacteria
Q35886272The Nox family of NAD(P)H oxidases: host defense and beyond
Q37335286The Overexpression of NALP3 Inflammasome in Knee Osteoarthritis Is Associated with Synovial Membrane Prolidase and NADPH Oxidase 2.
Q55344660The Pivotal Role of DNA Repair in Infection Mediated-Inflammation and Cancer.
Q40173612The Protein Disulfide Isomerase of Botrytis cinerea: An ER Protein Involved in Protein Folding and Redox Homeostasis Influences NADPH Oxidase Signaling Processes
Q42375776The ROS-generating oxidase Nox1 is required for epithelial restitution following colitis
Q36086638The Redox Code
Q36151496The Redox System in C. elegans, a Phylogenetic Approach
Q90050019The Role of Autophagy in Sepsis: Protection and Injury to Organs
Q90736521The Role of Hydrogen Peroxide and Peroxiredoxins throughout the Cell Cycle
Q46236716The Role of Nicotinamide Adenine Dinucleotide Phosphate Oxidases in Lung Architecture Remodeling
Q26771758The Role of Oxidative Stress in Neurodegenerative Diseases
Q27329515The adhesion GPCR BAI1 mediates macrophage ROS production and microbicidal activity against Gram-negative bacteria
Q34811358The angiotensin-converting enzyme 2/angiotensin (1-7)/Mas axis protects against lung fibroblast migration and lung fibrosis by inhibiting the NOX4-derived ROS-mediated RhoA/Rho kinase pathway
Q33858114The bacterial fermentation product butyrate influences epithelial signaling via reactive oxygen species-mediated changes in cullin-1 neddylation
Q26786137The balance of powers: Redox regulation of fibrogenic pathways in kidney injury
Q37705394The beneficial role of extracellular reactive oxygen species in apoptosis-induced compensatory proliferation
Q28395817The cysteine proteome
Q38455748The effect of endocannabinoid system in ischemia-reperfusion injury: a friend or a foe?
Q52843285The effect of nandrolone treatment with and without enforced swimming on histological and biochemical changes in the heart and coronary artery of male rats.
Q43018784The effect of tert-butyl hydroperoxide on hepatic transcriptome expression patterns in the striped sea bream (Lithognathus mormyrus; Teleostei).
Q46847292The effects of high glucose levels on reactive oxygen species-induced apoptosis and involved signaling in human vascular endothelial cells
Q60931584The effects of low-pressure hyperbaric oxygen treatment before and after maximal exercise on lactate concentration, heart rate recovery, and antioxidant capacity
Q52735764The effects of taurine on permethrininduced cytogenetic and oxidative damage in cultured human lymphocytes.
Q38981261The evolution of reactive oxygen species metabolism.
Q35232650The gut microbiota engages different signaling pathways to induce Duox2 expression in the ileum and colon epithelium
Q38464231The human Nox4: gene, structure, physiological function and pathological significance
Q38071791The impact of Toll-like receptors on bacterial virulence strategies
Q36692346The inflammatory response in stroke
Q24273363The influence of extracellular superoxide on iron redox chemistry and bioavailability to aquatic microorganisms
Q36129611The ins and outs of algal metal transport
Q35785384The intestinal microbiota are necessary for stressor-induced enhancement of splenic macrophage microbicidal activity
Q36739856The involvement of the tyrosine kinase c-Src in the regulation of reactive oxygen species generation mediated by NADPH oxidase-1.
Q43119448The isolated and combined effects of folic acid and synthetic bioactive compounds against Abeta(25-35)-induced toxicity in human microglial cells
Q24306260The kinase Btk negatively regulates the production of reactive oxygen species and stimulation-induced apoptosis in human neutrophils
Q37427782The liaison between apoptotic cells and macrophages--the end programs the beginning.
Q37783925The many roles of NOX2 NADPH oxidase-derived ROS in immunity
Q38169252The mechanisms and physiological relevance of glycocalyx degradation in hepatic ischemia/reperfusion injury
Q35132234The microglial NADPH oxidase complex as a source of oxidative stress in Alzheimer's disease
Q38139589The multifaceted functions of neutrophils
Q39383375The pathogenic development of Sclerotinia sclerotiorum in soybean requires specific host NADPH oxidases
Q38583113The pivotal role of reactive oxygen species generation in the hypoxia-induced stimulation of adipose-derived stem cells.
Q33997351The presence of p47phox in liver parenchymal cells is a key mediator in the pathogenesis of alcoholic liver steatosis
Q33653901The role of NOX enzymes in ethanol-induced oxidative stress and apoptosis in mouse embryos
Q92970041The role of NOX inhibitors in neurodegenerative diseases
Q37228570The role of reactive oxygen species in integrin and matrix metalloproteinase expression and function
Q34341080The role of the RB tumour suppressor pathway in oxidative stress responses in the haematopoietic system
Q92875049The role of the innate immune system in allergic contact dermatitis
Q34266689The role of the microglia in acute CNS injury
Q38084899The role of transcription-independent damage signals in the initiation of epithelial wound healing
Q26998373The serpentine path to a novel mechanism-based inhibitor of acute inflammatory lung injury
Q38155196The signaling pathway of NADPH oxidase and its role in glomerular diseases
Q42487257The superoxide-producing NAD(P)H oxidase Nox4 in the nucleus of human vascular endothelial cells
Q38858553Therapeutic potential of NADPH oxidase 1/4 inhibitors
Q37163360Thiol chemistry in peroxidase catalysis and redox signaling
Q37254377Thiol dependent intramolecular locking of Orai1 channels.
Q37694585Thiol redox systems and protein kinases in hepatic stellate cell regulatory processes
Q43204548Thioredoxin 1 downregulates MCP-1 secretion and expression in human endothelial cells by suppressing nuclear translocation of activator protein 1 and redox factor-1.
Q50904199Thioredoxin reductase 1 and NADPH directly protect protein tyrosine phosphatase 1B from inactivation during H2O2 exposure.
Q89874232Thioredoxin-1 distinctly promotes NF-κB target DNA binding and NLRP3 inflammasome activation independently of Txnip
Q28389739Thioredoxins, glutaredoxins, and peroxiredoxins--molecular mechanisms and health significance: from cofactors to antioxidants to redox signaling
Q89422441Time Dependent Pathway Activation of Signalling Cascades in Rat Organs after Short-Term Hyperoxia
Q37473166Tipping the redox balance of oxidative stress in fibrogenic pathways in chronic kidney disease
Q28586447Tks5-dependent, nox-mediated generation of reactive oxygen species is necessary for invadopodia formation
Q33231909TmpA, a member of a novel family of putative membrane flavoproteins, regulates asexual development in Aspergillus nidulans.
Q33515265TmpL, a transmembrane protein required for intracellular redox homeostasis and virulence in a plant and an animal fungal pathogen
Q38743977Toll-like receptor 4 deficiency causes pulmonary emphysema.
Q26865983Toll-like receptors: key players in antiviral immunity
Q41867180Towards understanding vacuolar antioxidant mechanisms: a role for fructans?
Q34793661Toxoplasma gondii Proliferation Require Down-Regulation of Host Nox4 Expression via Activation of PI3 Kinase/Akt Signaling Pathway
Q45259579TpMRK regulates cell division of Tetrahymena in response to oxidative stress
Q38317330Transcript analysis of early nodulation events in Medicago truncatula.
Q28387090Transcriptional activation of follistatin by Nrf2 protects pulmonary epithelial cells against silica nanoparticle-induced oxidative stress
Q47620767Transcriptome Assessment of Erythema Migrans Skin Lesions in Patients With Early Lyme Disease Reveals Predominant Interferon Signaling.
Q34163579Transcriptomic analysis comparing tumor-associated neutrophils with granulocytic myeloid-derived suppressor cells and normal neutrophils
Q46387801Transforming growth factor β1 (TGFβ1)-induced CD44V6-NOX4 signaling in pathogenesis of idiopathic pulmonary fibrosis
Q37258131Transient receptor potential A1 is a sensory receptor for multiple products of oxidative stress
Q27334687Treadmill exercise induces neutrophil recruitment into muscle tissue in a reactive oxygen species-dependent manner. An intravital microscopy study
Q36506880Trimetazidine prevents macrophage-mediated septic myocardial dysfunction via activation of the histone deacetylase sirtuin 1
Q34245882Triptolide inhibits IL-12/IL-23 expression in APCs via CCAAT/enhancer-binding protein alpha
Q27309286TrpA1 Regulates Defecation of Food-Borne Pathogens under the Control of the Duox Pathway
Q46402005Tumor promoter TPA stimulates MMP-9 secretion from human keratinocytes by activation of superoxide-producing NADPH oxidase.
Q46263540Tumor suppressor NPRL2 induces ROS production and DNA damage response
Q26744612Tuning of Redox Regulatory Mechanisms, Reactive Oxygen Species and Redox Homeostasis under Salinity Stress
Q37092831Two Rac paralogs regulate polarized growth in the human fungal pathogen Cryptococcus neoformans
Q30414139Unique role of NADPH oxidase 5 in oxidative stress in human renal proximal tubule cells
Q35126991Unraveling the role of FoxOs in bone--insights from mouse models
Q38786015Unravelling the relationship between macroautophagy and mitochondrial ROS in cancer therapy
Q43074599Up-regulation of a hydrogen peroxide-responsive pre-mRNA binding protein in atherosclerosis and intimal hyperplasia
Q28078744Update on Inflammatory Biomarkers and Treatments in Ischemic Stroke
Q41684953Update on Nox function, site of action and regulation in Botrytis cinerea
Q28472699Upregulation of xCT by KSHV-encoded microRNAs facilitates KSHV dissemination and persistence in an environment of oxidative stress
Q24597964Upsides and downsides of reactive oxygen species for cancer: the roles of reactive oxygen species in tumorigenesis, prevention, and therapy
Q33956678Uric acid: the oxidant-antioxidant paradox
Q36756452Use and abuse of exogenous H2O2 in studies of signal transduction
Q36636155VPO1 mediates ApoE oxidation and impairs the clearance of plasma lipids
Q35751091Vav proteins control MyD88-dependent oxidative burst
Q52714192Versatile Histochemical Approach to Detection of Hydrogen Peroxide in Cells and Tissues Based on Puromycin Staining.
Q42370291Viewpoints on Acid-induced inflammatory mediators in esophageal mucosa
Q36015158Visualization of vascular Ca2+ signaling triggered by paracrine derived ROS.
Q94484124Vitamin C and vitamin E in pregnant women at risk of pre-eclampsia
Q42814296Volume-sensitive NADPH oxidase activity and taurine efflux in NIH3T3 mouse fibroblasts
Q38921246Wear Particles Impair Antimicrobial Activity Via Suppression of Reactive Oxygen Species Generation and ERK1/2 Phosphorylation in Activated Macrophages
Q36209286Wolbachia and the insect immune system: what reactive oxygen species can tell us about the mechanisms of Wolbachia-host interactions
Q54253481[Biology of aging: theories, mechanisms, and perspectives].
Q28587018c-Ets1 inhibits the interaction of NF-κB and CREB, and downregulates IL-1β-induced MUC5AC overproduction during airway inflammation
Q34361024c-Src-mediated phosphorylation of NoxA1 and Tks4 induces the reactive oxygen species (ROS)-dependent formation of functional invadopodia in human colon cancer cells
Q42673185cDNA cloning, characterization and expression analysis of catalase in swimming crab Portunus trituberculatus: cDNA cloning and expression analysis of catalase gene of Portunus trituberculatus
Q59357741miR-155 Modulates Cockroach Allergen- and Oxidative Stress-Induced Cyclooxygenase-2 in Asthma
Q34490183p, p'-Dichlorodiphenyldichloroethylene induces colorectal adenocarcinoma cell proliferation through oxidative stress
Q36141979p-Cresyl sulfate aggravates cardiac dysfunction associated with chronic kidney disease by enhancing apoptosis of cardiomyocytes
Q37192211p40phox expression regulates neutrophil recruitment and function during the resolution phase of intestinal inflammation.
Q35860848p47phox-Nox2-dependent ROS Signaling Inhibits Early Bone Development in Mice but Protects against Skeletal Aging
Q34158115pO(2)-dependent NO production determines OPPC activity in macrophages
Q89747950trans-Fatty acids facilitate DNA damage-induced apoptosis through the mitochondrial JNK-Sab-ROS positive feedback loop

Search more.