scholarly article | Q13442814 |
P2093 | author name string | Thomas L Leto | |
Miklós Geiszt | |||
Takehiko Ueyama | |||
P2860 | cites work | Cell transformation by the superoxide-generating oxidase Mox1 | Q22010372 |
Novel Human Homologues of p47 and p67 Participate in Activation of Superoxide-producing NADPH Oxidases | Q24300616 | ||
Assembly of the phagocyte NADPH oxidase: binding of Src homology 3 domains to proline-rich targets | Q24328957 | ||
Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation | Q24678428 | ||
Structure of the TPR domain of p67phox in complex with Rac.GTP | Q27628646 | ||
Mouse model of X-linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production | Q28114945 | ||
Endomembrane trafficking of ras: the CAAX motif targets proteins to the ER and Golgi | Q28140190 | ||
Homologs of gp91phox: cloning and tissue expression of Nox3, Nox4, and Nox5 | Q28190953 | ||
Vestibular defects in head-tilt mice result from mutations in Nox3, encoding an NADPH oxidase | Q28249779 | ||
Direct interaction of the novel Nox proteins with p22phox is required for the formation of a functionally active NADPH oxidase | Q28277982 | ||
Rac translocates independently of the neutrophil NADPH oxidase components p47phox and p67phox. Evidence for its interaction with flavocytochrome b558. | Q46196991 | ||
NAD(P)H oxidases in rat basilar arterial endothelial cells. | Q46450271 | ||
Guanine nucleotide exchange regulates membrane translocation of Rac/Rho GTP-binding proteins. | Q46887698 | ||
Characterization of neutrophil NADPH oxidase factors p47-phox and p67-phox from recombinant baculoviruses. | Q52447388 | ||
Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1 | Q59053220 | ||
Characterization of two monoclonal antibodies against cytochrome b558 of human neutrophils | Q69063590 | ||
The cytosolic component p47(phox) is not a sine qua non participant in the activation of NADPH oxidase but is required for optimal superoxide production | Q71825234 | ||
Characterization of the effector-specifying domain of Rac involved in NADPH oxidase activation | Q71996707 | ||
Targeting of Rac1 to the phagocyte membrane is sufficient for the induction of NADPH oxidase assembly | Q73010796 | ||
NADPH oxidase | Q75301478 | ||
NOX3, a superoxide-generating NADPH oxidase of the inner ear | Q28278418 | ||
Novel gp91(phox) homologues in vascular smooth muscle cells : nox1 mediates angiotensin II-induced superoxide formation and redox-sensitive signaling pathways | Q28571066 | ||
Two novel proteins activate superoxide generation by the NADPH oxidase NOX1 | Q28585409 | ||
Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense | Q28609612 | ||
Tetratricopeptide repeat (TPR) motifs of p67(phox) participate in interaction with the small GTPase Rac and activation of the phagocyte NADPH oxidase | Q28609613 | ||
Regulation of phagocyte oxygen radical production by the GTP-binding protein Rac 2 | Q28609631 | ||
NOX enzymes and the biology of reactive oxygen | Q29547517 | ||
NOXO1, Regulation of Lipid Binding, Localization, and Activation of Nox1 by the Phox Homology (PX) Domain | Q30164408 | ||
Proteins homologous to p47phox and p67phox support superoxide production by NAD(P)H oxidase 1 in colon epithelial cells | Q30164806 | ||
Specificity of p47phox SH3 domain interactions in NADPH oxidase assembly and activation | Q30176592 | ||
NADPH oxidase activity is independent of p47phox in vitro | Q30176826 | ||
Assembly and activation of the phagocyte NADPH oxidase. Specific interaction of the N-terminal Src homology 3 domain of p47phox with p22phox is required for activation of the NADPH oxidase | Q30176829 | ||
Role of Src homology 3 domains in assembly and activation of the phagocyte NADPH oxidase | Q30194274 | ||
The NADPH oxidase Nox3 constitutively produces superoxide in a p22phox-dependent manner: its regulation by oxidase organizers and activators | Q33213948 | ||
The molecular basis for adhesion-mediated suppression of reactive oxygen species generation by human neutrophils | Q33630157 | ||
NADPH oxidase subunit, gp91(phox) homologue, preferentially expressed in human colon epithelial cells | Q33916755 | ||
NAD(P)H oxidase 1, a product of differentiated colon epithelial cells, can partially replace glycoprotein 91phox in the regulated production of superoxide by phagocytes | Q34207369 | ||
Ultrastructural localization of cytochrome b in the membranes of resting and phagocytosing human granulocytes | Q34245500 | ||
Nox3 regulation by NOXO1, p47phox, and p67phox. | Q34324985 | ||
Assembly of the phagocyte NADPH oxidase | Q34338562 | ||
Analysis of mRNA transcripts from the NAD(P)H oxidase 1 (Nox1) gene. Evidence against production of the NADPH oxidase homolog-1 short (NOH-1S) transcript variant | Q34349277 | ||
Alternative mRNA splice forms of NOXO1: differential tissue expression and regulation of Nox1 and Nox3. | Q34425599 | ||
Point mutations in the proline-rich region of p22phox are dominant inhibitors of Nox1- and Nox2-dependent reactive oxygen generation. | Q34430784 | ||
Current molecular models for NADPH oxidase regulation by Rac GTPase | Q34915029 | ||
Molecular mechanism for activation of superoxide-producing NADPH oxidases. | Q35638899 | ||
The Nox family of NAD(P)H oxidases: host defense and beyond | Q35886272 | ||
Sequential activation of phosphatidylinositol 3-kinase, beta Pix, Rac1, and Nox1 in growth factor-induced production of H2O2. | Q37732032 | ||
Isoform-specific membrane targeting mechanism of Rac during Fc gamma R-mediated phagocytosis: positive charge-dependent and independent targeting mechanism of Rac to the phagosome | Q40388422 | ||
Role of nicotinamide adenine dinucleotide phosphate oxidase 1 in oxidative burst response to Toll-like receptor 5 signaling in large intestinal epithelial cells | Q40587011 | ||
Biosynthesis of flavocytochrome b558 . gp91(phox) is synthesized as a 65-kDa precursor (p65) in the endoplasmic reticulum. | Q40975170 | ||
Two forms of autosomal chronic granulomatous disease lack distinct neutrophil cytosol factors. | Q42001699 | ||
Biosynthesis of the phagocyte NADPH oxidase cytochrome b558. Role of heme incorporation and heterodimer formation in maturation and stability of gp91phox and p22phox subunits | Q42835038 | ||
A fusion protein between rac and p67phox (1-210) reconstitutes NADPH oxidase with higher activity and stability than the individual components | Q43797270 | ||
Activation of the superoxide-generating NADPH oxidase by chimeric proteins consisting of segments of the cytosolic component p67(phox) and the small GTPase Rac1. | Q43809961 | ||
A prenylated p67phox-Rac1 chimera elicits NADPH-dependent superoxide production by phagocyte membranes in the absence of an activator and of p47phox: conversion of a pagan NADPH oxidase to monotheism | Q43918747 | ||
Dual role of Rac in the assembly of NADPH oxidase, tethering to the membrane and activation of p67phox: a study based on mutagenesis of p67phox-Rac1 chimeras | Q44755199 | ||
Helicobacter pylori lipopolysaccharide activates Rac1 and transcription of NADPH oxidase Nox1 and its organizer NOXO1 in guinea pig gastric mucosal cells | Q45094684 | ||
Functional association of nox1 with p22phox in vascular smooth muscle cells | Q45100914 | ||
Expression and localization of NOX2 and NOX4 in primary human endothelial cells | Q45261476 | ||
P433 | issue | 6 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | cell biology | Q7141 |
P304 | page(s) | 2160-74 | |
P577 | publication date | 2006-03-01 | |
P1433 | published in | Molecular and Cellular Biology | Q3319478 |
P1476 | title | Involvement of Rac1 in activation of multicomponent Nox1- and Nox3-based NADPH oxidases | |
P478 | volume | 26 |
Q34181387 | A Conserved Region between the TPR and Activation Domains of p67 Participates in Activation of the Phagocyte NADPH Oxidase |
Q48166066 | A Novel Rac1-GSPT1 Signaling Pathway Controls Astrogliosis Following Central Nervous System Injury |
Q33660799 | A novel and specific NADPH oxidase-1 (Nox1) small-molecule inhibitor blocks the formation of functional invadopodia in human colon cancer cells |
Q92877857 | Acquired Resistance of EGFR-Mutated Lung Cancer to Tyrosine Kinase Inhibitor Treatment Promotes PARP Inhibitor Sensitivity |
Q37010696 | Activated Rac1 regulates the degradation of IκBα and the nuclear translocation of STAT3-NFκB complexes in starved cancer cells |
Q38301030 | Adipocyte differentiation induced using nonspecific siRNA controls in cultured human mesenchymal stem cells. |
Q39756367 | Anthrax edema toxin inhibits Nox1-mediated formation of reactive oxygen species by colon epithelial cells |
Q39871422 | Bcr-Abl-mediated redox regulation of the PI3K/AKT pathway |
Q26991619 | Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system |
Q36844052 | Co-regulation of constitutive nitric oxide synthases and NADPH oxidase by the small GTPase Rac |
Q39646559 | Constitutive NADPH-dependent electron transferase activity of the Nox4 dehydrogenase domain |
Q35562465 | Cooperation of p40(phox) with p47(phox) for Nox2-based NADPH oxidase activation during Fcγ receptor (FcγR)-mediated phagocytosis: mechanism for acquisition of p40(phox) phosphatidylinositol 3-phosphate (PI(3)P) binding |
Q24678301 | Critical roles for p22phox in the structural maturation and subcellular targeting of Nox3 |
Q42512928 | Cross talk between increased intracellular zinc (Zn2+) and accumulation of reactive oxygen species in chemical ischemia |
Q36516796 | Crosstalk between Bcl-2 family and Ras family small GTPases: potential cell fate regulation? |
Q43483426 | Cyanidin-3-glucoside suppresses TNF-α-induced cell proliferation through the repression of Nox activator 1 in mouse vascular smooth muscle cells: involvement of the STAT3 signaling |
Q28256579 | Deletion mutagenesis of p22phox subunit of flavocytochrome b558: identification of regions critical for gp91phox maturation and NADPH oxidase activity |
Q45345920 | Direct involvement of the small GTPase Rac in activation of the superoxide-producing NADPH oxidase Nox1. |
Q33818148 | Downstream targets and intracellular compartmentalization in Nox signaling |
Q37139797 | Duox maturation factors form cell surface complexes with Duox affecting the specificity of reactive oxygen species generation |
Q28512867 | Endosomal NADPH oxidase regulates c-Src activation following hypoxia/reoxygenation injury |
Q36972740 | Endothelin (ET)-1 inhibits nicotinamide adenine dinucleotide phosphate oxidase activity in human abdominal aortic endothelial cells: a novel function of ETB1 receptors |
Q41850485 | Eplerenone suppresses aldosterone/ salt-induced expression of NOX-4. |
Q46527889 | Essential role of NOXA1 in generation of reactive oxygen species induced by oxidized low-density lipoprotein in human vascular endothelial cells |
Q26861119 | Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement |
Q24299330 | From death receptor to reactive oxygen species and c-Jun N-terminal protein kinase: the receptor-interacting protein 1 odyssey |
Q92242992 | Function of NADPH Oxidases in Diabetic Nephropathy and Development of Nox Inhibitors |
Q39334544 | Functional Role of Nox4 in Autophagy. |
Q42775534 | Gene-Diet Interactions on Colorectal Cancer Risk |
Q39124376 | Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes |
Q45960055 | IL-17 stimulates the proliferation and differentiation of human mesenchymal stem cells: implications for bone remodeling. |
Q24311930 | Identification of a conserved Rac-binding site on NADPH oxidases supports a direct GTPase regulatory mechanism |
Q58610285 | Identification of novel regulatory partners of the glutamate transporter GLT-1 |
Q24655002 | Inhibitory action of NoxA1 on dual oxidase activity in airway cells |
Q24319711 | Interaction between the SH3 domains and C-terminal proline-rich region in NADPH oxidase organizer 1 (Noxo1) |
Q30490061 | Invasion of endothelial cells by tissue-invasive M3 type group A streptococci requires Src kinase and activation of Rac1 by a phosphatidylinositol 3-kinase-independent mechanism |
Q37250677 | Involvement of betaPIX in angiotensin II-induced migration of vascular smooth muscle cells |
Q93179119 | Loss of Scribble confers cisplatin resistance during NSCLC chemotherapy via Nox2/ROS and Nrf2/PD-L1 signaling |
Q35287869 | Loss of the tumor suppressor Hace1 leads to ROS-dependent glutamine addiction |
Q40057005 | Mechanism of angiotensin II-induced superoxide production in cells reconstituted with angiotensin type 1 receptor and the components of NADPH oxidase |
Q33300608 | Molecular evolution of Phox-related regulatory subunits for NADPH oxidase enzymes |
Q37111033 | Mucosal reactive oxygen species decrease virulence by disrupting Campylobacter jejuni phosphotyrosine signaling. |
Q38936778 | Myc and Ras oncogenes engage different energy metabolism programs and evoke distinct patterns of oxidative and DNA replication stress |
Q33860500 | NADPH oxidase 1, a novel molecular source of ROS in hippocampal neuronal death in vascular dementia |
Q24299314 | NADPH oxidase 5 (NOX5) interacts with and is regulated by calmodulin |
Q37589114 | NADPH oxidase in brain injury and neurodegenerative disorders |
Q41786123 | NADPH oxidase-generated reactive oxygen species are required for stromal cell-derived factor-1α-stimulated angiogenesis |
Q54216652 | NADPH oxidases and ROS signaling in the gastrointestinal tract. |
Q37342232 | NADPH oxidases and angiotensin II receptor signaling |
Q33632660 | NADPH oxidases: a perspective on reactive oxygen species production in tumor biology |
Q36302873 | NADPH oxidases: an overview from structure to innate immunity-associated pathologies |
Q37169101 | NOX enzymes and Toll-like receptor signaling. |
Q50299247 | NOX3 complex:RAC1:GTP generates superoxide from oxygen |
Q39596144 | Neuregulin induces HaCaT keratinocyte migration via Rac1-mediated NADPH-oxidase activation |
Q39635208 | Normobaric hyperoxia protects the blood brain barrier through inhibiting Nox2 containing NADPH oxidase in ischemic stroke |
Q24316184 | Novel p47(phox)-related organizers regulate localized NADPH oxidase 1 (Nox1) activity |
Q35824748 | Nox Inhibitors & Therapies: Rational Design of Peptidic and Small Molecule Inhibitors |
Q28282472 | Nox enzymes and oxidative stress in the immunopathology of the gastrointestinal tract |
Q37151978 | Nox enzymes in immune cells |
Q37392163 | Nox proteins in signal transduction |
Q24296828 | Nox1 activation by βPix and the role of Ser-340 phosphorylation |
Q24320021 | Nox1-dependent reactive oxygen generation is regulated by Rac1 |
Q35213232 | Nox4: a hydrogen peroxide-generating oxygen sensor |
Q36544047 | Overexpression of Bcl-2 induces STAT-3 activation via an increase in mitochondrial superoxide |
Q28393242 | Oxidases and peroxidases in cardiovascular and lung disease: new concepts in reactive oxygen species signaling |
Q90260610 | Oxidative Stress in Pulmonary Fibrosis |
Q35964957 | PVN adenovirus-siRNA injections silencing either NOX2 or NOX4 attenuate aldosterone/NaCl-induced hypertension in mice |
Q30008984 | Peroxiredoxin 6 (Prdx6) supports NADPH oxidase1 (Nox1)-based superoxide generation and cell migration |
Q37261114 | Phosphorylation of Nox1 regulates association with NoxA1 activation domain. |
Q24318670 | Phosphorylation of Noxo1 at threonine 341 regulates its interaction with Noxa1 and the superoxide-producing activity of Nox1 |
Q37976066 | Physiological roles of NOX/NADPH oxidase, the superoxide-generating enzyme |
Q37184946 | Prevention of TNF-induced necrotic cell death by rottlerin through a Nox1 NADPH oxidase |
Q106518963 | RAC1 binds effectors at the plasma membrane |
Q50299246 | RAC1:GTP binds NOX3 complex |
Q49366921 | RCC2 over-expression in tumor cells alters apoptosis and drug sensitivity by regulating Rac1 activation. |
Q45318309 | RHO GTPase Effectors |
Q45318323 | RHO GTPases Activate NADPH Oxidases |
Q41757708 | ROS-Generating Oxidase Nox3 Regulates the Self-Renewal of Mouse Spermatogonial Stem Cells |
Q41920499 | Rac1 expression by fibroblasts is required for tissue repair in vivo |
Q64950759 | Rac1 promotes the survival of H9c2 cells during serum deficiency targeting JNK/c-JUN/Cyclin-D1 and AKT2/MCL1 pathways. |
Q38790849 | Rac1b enhances cell survival through activation of the JNK2/c-JUN/Cyclin-D1 and AKT2/MCL1 pathways |
Q35987578 | Redox modifier genes in amyotrophic lateral sclerosis in mice. |
Q36451514 | Redox regulation of Rac1 by thiol oxidation. |
Q30156868 | Regulation of NOXO1 activity through reversible interactions with p22 and NOXA1. |
Q36865824 | Regulation of Nox and Duox enzymatic activity and expression |
Q37461363 | Regulation of reactive oxygen species generation in cell signaling |
Q26823042 | Rho GTPases, oxidation, and cell redox control |
Q64244340 | Rho-Family Small GTPases: From Highly Polarized Sensory Neurons to Cancer Cells |
Q35741503 | Role of Rac1 in regulation of NOX5-S function in Barrett's esophageal adenocarcinoma cells |
Q35009071 | Role of neuronal NADPH oxidase 1 in the peri-infarct regions after stroke |
Q43061685 | Role of the NADPH oxidase systems Nox and Duox in host defense and inflammation |
Q24307703 | SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model |
Q45318307 | Signaling by Rho GTPases |
Q28267075 | Structural insights into Nox4 and Nox2: motifs involved in function and cellular localization |
Q28282131 | Structure, regulation and evolution of Nox-family NADPH oxidases that produce reactive oxygen species |
Q35792499 | Subcellular localization and function of alternatively spliced Noxo1 isoforms |
Q30491877 | Targeting and regulation of reactive oxygen species generation by Nox family NADPH oxidases |
Q34135661 | The Nonphagocytic NADPH Oxidase Duox1 Mediates a Positive Feedback Loop During T Cell Receptor Signaling |
Q39836858 | The insert region of the Rac GTPases is dispensable for activation of superoxide-producing NADPH oxidases |
Q36739856 | The involvement of the tyrosine kinase c-Src in the regulation of reactive oxygen species generation mediated by NADPH oxidase-1. |
Q39850050 | The role of NADPH oxidase 1-derived reactive oxygen species in paraquat-mediated dopaminergic cell death |
Q48291439 | The role of Pak-interacting exchange factor-β phosphorylation at serines 340 and 583 by PKCγ in dopamine release |
Q38743977 | Toll-like receptor 4 deficiency causes pulmonary emphysema. |
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Q34207197 | Tumor necrosis factor-α-induced colitis increases NADPH oxidase 1 expression, oxidative stress, and neutrophil recruitment in the colon: preventive effect of apocynin |
Q34403921 | Updates of reactive oxygen species in melanoma etiology and progression |
Q46287916 | hace1 Influences zebrafish cardiac development via ROS-dependent mechanisms |
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