RAC1 binds effectors at the plasma membrane

instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-9013145)

RAC1 binds effectors at the plasma membrane is …
instance of (P31):
biological processQ2996394

External links are
P2888exact matchhttps://identifiers.org/reactome:R-HSA-9013145
P3937Reactome IDR-HSA-9013145

P2860cites workCitron rho-interacting kinase, a novel tissue-specific ser/thr kinase encompassing the Rho-Rac-binding protein CitronQ22004169
PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodiaQ22008024
WAVE, a novel WASP-family protein involved in actin reorganization induced by RacQ22008483
The Rac1 polybasic region is required for interaction with its effector PRK1Q24300612
Biochemical characterization of the Rho GTPase-regulated actin assembly by diaphanous-related formins, mDia1 and Daam1, in plateletsQ24307657
Identification of a conserved Rac-binding site on NADPH oxidases supports a direct GTPase regulatory mechanismQ24311930
The Ras GTPase-activating-protein-related human protein IQGAP2 harbors a potential actin binding domain and interacts with calmodulin and Rho family GTPasesQ24316220
Nox1-dependent reactive oxygen generation is regulated by Rac1Q24320021
PAK5, a new brain-specific kinase, promotes neurite outgrowth in N1E-115 cellsQ24540039
Involvement of Rac1 in activation of multicomponent Nox1- and Nox3-based NADPH oxidasesQ24548021
FRL, a novel formin-related protein, binds to Rac and regulates cell motility and survival of macrophagesQ24551450
The Borgs, a new family of Cdc42 and TC10 GTPase-interacting proteinsQ24554429
The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeletonQ24648481
Molecular dissection of the interaction between the small G proteins Rac1 and RhoA and protein kinase C-related kinase 1 (PRK1)Q27642233
A human homolog of the C. elegans polarity determinant Par-6 links Rac and Cdc42 to PKCzeta signaling and cell transformationQ28139572
AR and ER Interaction with a p21-Activated Kinase (PAK6)Q28214409
Rac1 and RhoG promote cell survival by the activation of PI3K and Akt, independently of their ability to stimulate JNK and NF-kappaBQ28216113
A brain serine/threonine protein kinase activated by Cdc42 and Rac1Q28249559
A novel partner for the GTP-bound forms of rho and racQ28272116
Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domainQ28281838
IQGAP3, a novel effector of Rac1 and Cdc42, regulates neurite outgrowthQ28284657
Identification of IQGAP as a putative target for the small GTPases, Cdc42 and Rac1Q28289256
Molecular cloning of a new member of the p21-Cdc42/Rac-activated kinase (PAK) familyQ28289551
Two GTPases, Cdc42 and Rac, bind directly to a protein implicated in the immunodeficiency disorder Wiskott-Aldrich syndromeQ28289697
Characterization of two alternately spliced forms of phospholipase D1. Activation of the purified enzymes by phosphatidylinositol 4,5-bisphosphate, ADP-ribosylation factor, and Rho family monomeric GTP-binding proteins and protein kinase C-alphaQ28302448
Novel role of gp91(phox)-containing NAD(P)H oxidase in vascular endothelial growth factor-induced signaling and angiogenesisQ28609623
Pak1 kinase homodimers are autoinhibited in trans and dissociated upon activation by Cdc42 and Rac1Q28609687
Loop 6 of RhoA confers specificity for effector binding, stress fiber formation, and cellular transformationQ28609748
Rac GTPase interacts specifically with phosphatidylinositol 3-kinaseQ28646209
Optimization of WAVE2 complex-induced actin polymerization by membrane-bound IRSp53, PIP(3), and Rac.Q30480399
Molecular cloning and characterization of a novel human STE20-like kinase, hSLK.Q30645733
Sema3A-induced growth-cone collapse is mediated by Rac1 amino acids 17-32.Q33875867
Serine-71 phosphorylation of Rac1 modulates downstream signalingQ34412353
Role of the small GTPase Rac in p22phox-dependent NADPH oxidasesQ36855140
The IQGAP1 protein is a calmodulin-regulated barbed end capper of actin filaments: possible implications in its function in cell migrationQ38621819
ARF1 controls Rac1 signaling to regulate migration of MDA-MB-231 invasive breast cancer cellsQ39147569
Regulation of p21-activated kinase-independent Rac1 signal transduction by nischarinQ40400674
FMNL2 drives actin-based protrusion and migration downstream of Cdc42.Q42188467
Direct involvement of the small GTPase Rac in activation of the superoxide-producing NADPH oxidase Nox1.Q45345920
Focal-adhesion targeting links caveolin-1 to a Rac1-degradation pathwayQ45356152
Unraveling the molecular mechanism of interactions of the Rho GTPases Cdc42 and Rac1 with the scaffolding protein IQGAP2.Q47564438
Mapping the proximity interaction network of the Rho-family GTPases reveals signalling pathways and regulatory mechanismsQ92218386
P703found in taxonHomo sapiensQ15978631
P527has part(s)RAC1:GTP [plasma membrane]Q50253918
RAC1 effectors [cytosol]Q106512994
RAC1:GTP:RAC1 effectors [plasma membrane]Q106512995
P361part ofRAC1 GTPase cycleQ106520262

Reverse relations

part of (P361)
Q106512994RAC1 effectors [cytosol]
Q50253918RAC1:GTP [plasma membrane]
Q106512995RAC1:GTP:RAC1 effectors [plasma membrane]

Q106520262RAC1 GTPase cyclehas part(s)P527