Novel role of gp91(phox)-containing NAD(P)H oxidase in vascular endothelial growth factor-induced signaling and angiogenesis

scientific journal article

Novel role of gp91(phox)-containing NAD(P)H oxidase in vascular endothelial growth factor-induced signaling and angiogenesis is …
instance of (P31):
scholarly articleQ13442814
retracted paperQ45182324

External links are
P356DOI10.1161/01.RES.0000046227.65158.F8
P3181OpenCitations bibliographic resource ID3993308
P698PubMed publication ID12480817

P2093author name stringYan Tang
Masuko Ushio-Fukai
Mitsuaki Fujimoto
Tohru Fukai
Chad Johnson
R. Wayne Alexander
Patrick J. Pagano
Yuxian Ma
Mark T. Quinn
Sergey I. Dikalov
P2860cites workVascular endothelial growth factor activates nuclear factor-kappaB and induces monocyte chemoattractant protein-1 in bovine retinal endothelial cellsQ77759136
On the possible role of reactive oxygen species in angiogenesisQ77797946
Mouse model of X-linked chronic granulomatous disease, an inherited defect in phagocyte superoxide productionQ28114945
Differential activation of mitogen-activated protein kinases by H2O2 and O2- in vascular smooth muscle cellsQ28566071
NAD(P)H oxidase: role in cardiovascular biology and diseaseQ29616102
Signal transduction by reactive oxygen species in non-phagocytic cells.Q33542052
Novel homologs of gp91phox.Q34069745
Sphingosine 1-phosphate signalling via the endothelial differentiation gene family of G-protein-coupled receptorsQ34126142
The NADPH oxidase of endothelial cellsQ34235453
Topological mapping of neutrophil cytochrome b epitopes with phage-display librariesQ36688465
Protection from reoxygenation injury by inhibition of rac1.Q37381258
Stimulation of in vitro angiogenesis by hydrogen peroxide and the relation with ETS-1 in endothelial cellsQ38327866
Epidermal growth factor receptor transactivation by angiotensin II requires reactive oxygen species in vascular smooth muscle cells.Q43576435
Vascular endothelial growth factor induces manganese‐superoxide dismutase expression in endothelial cells by a Racl‐regulated NADPH oxidase‐dependent mechanismQ43771298
Reactive oxygen species as downstream mediators of angiogenic signaling by vascular endothelial growth factor receptor-2/KDR.Q43806613
Noninvasive diagnostic tool for inflammation-induced oxidative stress using electron spin resonance spectroscopy and an extracellular cyclic hydroxylamineQ44018844
Expression of a functionally active gp91phox-containing neutrophil-type NAD(P)H oxidase in smooth muscle cells from human resistance arteries: regulation by angiotensin II.Q44028496
Inhibition of NADPH oxidase activation by 4-(2-aminoethyl)-benzenesulfonyl fluoride and related compoundsQ46469206
A Rac1 Effector Site Controlling Mitogenesis through Superoxide ProductionQ47860128
p38 Mitogen-activated protein kinase is a critical component of the redox-sensitive signaling pathways activated by angiotensin II. Role in vascular smooth muscle cell hypertrophyQ48010552
Increased H2O2, vascular endothelial growth factor and receptors in the retina of the BBZ/Wor diabetic rat.Q52537902
A gp91phox Containing NADPH Oxidase Selectively Expressed in Endothelial Cells Is a Major Source of Oxygen Radical Generation in the Arterial WallQ60723097
The actin cytoskeleton reorganization induced by Rac1 requires the production of superoxideQ64380055
Characteristics of the inhibition of NADPH oxidase activation in neutrophils by apocynin, a methoxy-substituted catecholQ72031040
NADPH oxidase activity is required for endothelial cell proliferation and migrationQ73303463
Induction of vascular endothelial growth factor in balloon-injured baboon arteries. A novel role for reactive oxygen species in atherosclerosisQ73454257
P433issue12
P921main subjectendotheliumQ111140
angiogenesisQ539568
P304page(s)1160–1167
P577publication date2002-12-13
P1433published inCirculation ResearchQ2599020
P1476titleNovel role of gp91(phox)-containing NAD(P)H oxidase in vascular endothelial growth factor-induced signaling and angiogenesis
P478volume91

Reverse relations

cites work (P2860)
Q3797402420-HETE in neovascularization
Q4209801420-HETE increases superoxide production and activates NAPDH oxidase in pulmonary artery endothelial cells.
Q3713897120-HETE increases survival and decreases apoptosis in pulmonary arteries and pulmonary artery endothelial cells
Q87680073A Chinese 2-herb formula (NF3) promotes hindlimb ischemia-induced neovascularization and wound healing of diabetic rats
Q33648934A ligand-independent VEGFR2 signaling pathway limits angiogenic responses in diabetes
Q44391230A radical adventure: the quest for specific functions and inhibitors of vascular NAPDH oxidases
Q42538987A role for NADPH oxidase 4 in the activation of vascular endothelial cells by oxidized phospholipids
Q40563957Activation of vascular endothelial growth factor receptor-3 and its downstream signaling promote cell survival under oxidative stress
Q34571046Acute NADPH oxidase activation potentiates cerebrovascular permeability response to bradykinin in ischemia-reperfusion
Q46759092Adiponectin inhibits vascular endothelial growth factor-induced migration of human coronary artery endothelial cells
Q80782253Administration of pigment epithelium-derived factor (PEDF) inhibits cold injury-induced brain edema in mice
Q44799753Advanced glycation end-products increase monocyte adhesion to retinal endothelial cells through vascular endothelial growth factor-induced ICAM-1 expression: inhibitory effect of antioxidants.
Q36906269Adventitial fibroblast reactive oxygen species as autacrine and paracrine mediators of remodeling: bellwether for vascular disease?
Q46622856Aerobic training and angiogenesis activation in patients with stable chronic heart failure: a preliminary report
Q42096169Altered hypoxia-inducible factor-1 alpha expression levels correlate with coronary vessel anomalies
Q83133100An arylidene-thiazolidinedione derivative, GPU-4, without PPARγ activation, reduces retinal neovascularization
Q37287612An ezrin/calpain/PI3K/AMPK/eNOSs1179 signaling cascade mediating VEGF-dependent endothelial nitric oxide production
Q80363039Analysis of dihydroethidium fluorescence for the detection of intracellular and extracellular superoxide produced by NADPH oxidase
Q43148412Angiogenesis and blood vessel stability in inflammatory arthritis
Q50328661Angiogenesis modulation by exogenous antioxidants
Q26777977Angiomodulatory properties of Rhodiola spp. and other natural antioxidants
Q80340580Angiopoietin-1 attenuates H2O2-induced SEK1/JNK phosphorylation through the phosphatidylinositol 3-kinase/Akt pathway in vascular endothelial cells
Q28508304Angiopoietin-1 requires p190 RhoGAP to protect against vascular leakage in vivo
Q83297534Angiopoietin-1-induced angiogenesis is modulated by endothelial NADPH oxidase
Q48582431Angiotensin type 1 receptor blockage reduces l-dopa-induced dyskinesia in the 6-OHDA model of Parkinson's disease. Involvement of vascular endothelial growth factor and interleukin-1β.
Q38924590Anti-angiogenic activity of macrolactin A and its succinyl derivative is mediated through inhibition of class I PI3K activity and its signaling
Q53355953Anti-angiogenic effect of luteolin on retinal neovascularization via blockade of reactive oxygen species production
Q39348667Anti-metastatic and anti-angiogenic properties of potential new anti-cancer drugs based on metal complexes of selenosemicarbazones
Q46432420Antiangiogenic activity of 4-O-methylgallic acid from Canavalia gladiata, a dietary legume
Q42838837Antiatherogenic effect of bisvanillyl-hydralazone, a new hydralazine derivative with antioxidant, carbonyl scavenger, and antiapoptotic properties.
Q38501183Antioxidant Therapy: Is it your Gateway to Improved Cardiovascular Health?
Q85245597Antioxidant and antiangiogenic properties of phenolic extract from Pleurotus tuber-regium
Q44948972Antioxidant intervention prevents renal neovascularization in hypercholesterolemic pigs
Q45006846Antioxidants inhibit angiogenesis in vivo through down-regulation of nitric oxide synthase expression and activity.
Q45290155Antioxidants inhibit human endothelial cell functions through down-regulation of endothelial nitric oxide synthase activity
Q39153631Apocynin, an NADPH oxidase inhibitor, suppresses progression of prostate cancer via Rac1 dephosphorylation.
Q37164272Arsenic requires sphingosine-1-phosphate type 1 receptors to induce angiogenic genes and endothelial cell remodeling
Q44725177Assessment of renal functional phenotype in mice lacking gp91PHOX subunit of NAD(P)H oxidase
Q34586951Association between NADPH Oxidase p22phox C242T Polymorphism and Ischemic Cerebrovascular Disease: A Meta-Analysis
Q36017360Association of the NAD(P)H oxidase p22 phox gene C242T polymorphism with type 2 diabetes mellitus, diabetic nephropathy, and carotid atherosclerosis with type 2 diabetes mellitus: A meta-analysis
Q30886863Bee products prevent VEGF-induced angiogenesis in human umbilical vein endothelial cells
Q45855269Benfotiamine accelerates the healing of ischaemic diabetic limbs in mice through protein kinase B/Akt-mediated potentiation of angiogenesis and inhibition of apoptosis
Q41904227Bidirectional interactions between NOX2-type NADPH oxidase and the F-actin cytoskeleton in neuronal growth cones
Q38159735Bioactive lipids in pathological retinopathy
Q26991619Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system
Q31146191Blockade of advanced glycation end-product formation restores ischemia-induced angiogenesis in diabetic mice
Q39184446Bone marrow-derived cells play a major role in kidney fibrosis via proliferation and differentiation in the infiltrated site.
Q46856589Bone morphogenic protein-4-induced oxidant signaling via protein carbonylation for endothelial dysfunction.
Q55041823Carbazole is a naturally occurring inhibitor of angiogenesis and inflammation isolated from antipsoriatic coal tar.
Q34987834Cathepsin B and uPAR knockdown inhibits tumor-induced angiogenesis by modulating VEGF expression in glioma
Q30539574Cell-trappable fluorescent probes for endogenous hydrogen sulfide signaling and imaging H2O2-dependent H2S production.
Q28397579Cellular and molecular mechanisms underlying alcohol-induced aggressiveness of breast cancer
Q34297316Cerebral amyloid angiopathy impact on endothelium
Q92486308Cerebrovascular inflammation: A critical trigger for neurovascular injury?
Q83514147Changes by tacrolimus of the rat aortic proteome: involvement of endothelin-1
Q46617718Chronic L-arginine administration increases oxidative and nitrosative stress in rat hyperoxaluric kidneys and excessive crystal deposition
Q45235332Circulating progenitor cells and the elderly: a seven-year observational study.
Q62030629Circulating progenitor cells are increased in newly diagnosed untreated hypertensive patients with arterial stiffening but normal carotid intima-media thickness
Q45335007Circulating progenitor cells in rheumatoid arthritis: association with inflammation and oxidative stress.
Q38324442Common pathways in health benefit properties of RSV in cardiovascular diseases, cancers and degenerative pathologies
Q46578290Comparison of cardioprotective effects using salvianolic acid B and benazepril for the treatment of chronic myocardial infarction in rats
Q46409865Comparison of the signaling mechanisms by which VEGF, H2O2, and phosphatase inhibitors activate endothelial cell ERK1/2 MAP-kinase
Q37322476Compartmentalization of redox signaling through NADPH oxidase-derived ROS.
Q93020905Concomitant overexpression of triple antioxidant enzymes selectively increases circulating endothelial progenitor cells in mice with limb ischaemia
Q37418503Coordinated role of voltage-gated sodium channels and the Na+/H+ exchanger in sustaining microglial activation during inflammation.
Q26772290Critical Roles of Reactive Oxygen Species in Age-Related Impairment in Ischemia-Induced Neovascularization by Regulating Stem and Progenitor Cell Function
Q46380299Critical role of the NADPH oxidase subunit p47phox on vascular TLR expression and neointimal lesion formation in high-fat diet-induced obesity
Q38132120Current status of NADPH oxidase research in cardiovascular pharmacology
Q52925752Deficient angiogenesis in redox-dead Cys17Ser PKARIα knock-in mice
Q33649275Diabetes and vessel wall remodelling: from mechanistic insights to regenerative therapies.
Q27322671Differential regulation of TRPV1 channels by H2O2: implications for diabetic microvascular dysfunction.
Q37971795Differential roles of NADPH oxidases in vascular physiology and pathophysiology
Q37260191Differential vascular functions of Nox family NADPH oxidases
Q34092503Direct Sensing of Endothelial Oxidants by Vascular Endothelial Growth Factor Receptor-2 and c-Src
Q37941867Do statins have a role in reduction/prevention of post-PCI restenosis?
Q33818148Downstream targets and intracellular compartmentalization in Nox signaling
Q39057795ETS transcription factor ETV2/ER71/Etsrp in hematopoietic and vascular development, injury, and regeneration
Q39830292Early signaling by vascular endothelial growth factor and placental growth factor in human bone marrow-derived endothelial cells is mediated by superoxide
Q35971126Edaravone is a free radical scavenger that protects against laser-induced choroidal neovascularization in mice and common marmosets
Q33914406Effects of Aging on Angiogenesis
Q42203698Effects of Xin-Ji-Er-Kang formula on 2K1C-induced hypertension and cardiovascular remodeling in rats
Q64098721Effects of bradykinin on the survival of multiterritory perforator flaps in rats
Q36432630Effects of calcitriol on random skin flap survival in rats
Q39938495Effects of cyclic strain on endothelial cell apoptosis and tubulogenesis are dependent on ROS production via NAD(P)H subunit p22phox
Q47108920Effects of puerarin on the retina and STAT3 expression in diabetic rats
Q37812765Effects of resveratrol and other wine polyphenols on vascular function: an update
Q28588321Effects of thioredoxin reductase-1 deletion on embryogenesis and transcriptome
Q36042713Emerging role of PKA/eNOS pathway in therapeutic angiogenesis for ischaemic tissue diseases
Q35947546Endothelial Dysfunction and Diabetes: Effects on Angiogenesis, Vascular Remodeling, and Wound Healing
Q42798882Endothelial Progenitor Cells=EPC=Elemental Pernicious Complexity
Q37223876Endothelial cell junctions and the regulation of vascular permeability and leukocyte transmigration
Q35913809Endothelial cell superoxide generation: regulation and relevance for cardiovascular pathophysiology.
Q37125689Endothelial signaling in paracellular and transcellular leukocyte transmigration
Q30496168Endothelium-dependent coronary vasodilatation requires NADPH oxidase-derived reactive oxygen species
Q36977680Epoxyeicosatrienoic acids are part of the VEGF-activated signaling cascade leading to angiogenesis.
Q33666049Essential Role of Copper-Zinc Superoxide Dismutase for Ischemia-Induced Neovascularization Via Modulation of Bone Marrow–Derived Endothelial Progenitor Cells
Q33761211European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).
Q39407718Evaluation of cellular response to perfluorooctane sulfonate in human umbilical vein endothelial cells.
Q38041505Evolving concepts of oxidative stress and reactive oxygen species in cardiovascular disease.
Q33205904Exogenous NADPH increases cerebral blood flow through NADPH oxidase-dependent and -independent mechanisms
Q37467798Extracellular SOD and VEGF are increased in vitreous bodies from proliferative diabetic retinopathy patients.
Q33565541Extracellular SOD-derived H2O2 promotes VEGF signaling in caveolae/lipid rafts and post-ischemic angiogenesis in mice
Q37576023Far-infrared protects vascular endothelial cells from advanced glycation end products-induced injury via PLZF-mediated autophagy in diabetic mice.
Q24312013Fibulin-5 is a novel binding protein for extracellular superoxide dismutase
Q37191663Function of reactive oxygen species during animal development: passive or active?
Q40195197Functional implication of BMP4 expression on angiogenesis in malignant melanoma
Q28199073Functional role of NADPH oxidase in activation of platelets
Q38253183Gene therapy for chronic granulomatous disease: current status and future perspectives.
Q42452009Glucose 6-phosphate dehydrogenase is regulated through c-Src-mediated tyrosine phosphorylation in endothelial cells
Q30939997Glucose-6-phosphate dehydrogenase modulates vascular endothelial growth factor-mediated angiogenesis
Q37415671Glutathione peroxidases in different stages of carcinogenesis
Q43470500Green tea intake, ACE gene polymorphism and breast cancer risk among Chinese women in Singapore
Q34894079Grifola frondosa (maitake mushroom) water extract inhibits vascular endothelial growth factor-induced angiogenesis through inhibition of reactive oxygen species and extracellular signal-regulated kinase phosphorylation
Q28538396HIV-1/cocaine induced oxidative stress disrupts tight junction protein-1 in human pulmonary microvascular endothelial cells: role of Ras/ERK1/2 pathway
Q33641974HMG-CoA reductase inhibitors (statin) prevents retinal neovascularization in a model of oxygen-induced retinopathy.
Q82471490Heme oxygenase attenuates oxidative stress and inflammation, and increases VEGF expression in portal hypertensive rats
Q37559355Hemorrhagic transformation after ischemic stroke in animals and humans
Q54635450Hepatocyte growth factor induces a proangiogenic phenotype and mobilizes endothelial progenitor cells by activating Nox2.
Q45881660Hepatocyte growth factor, but not vascular endothelial growth factor, attenuates angiotensin II-induced endothelial progenitor cell senescence
Q42906480High DNA oxidative damage in systemic sclerosis
Q28180577Honokiol, a small molecular weight natural product, inhibits angiogenesis in vitro and tumor growth in vivo
Q34379685Human urotensin II is a novel activator of NADPH oxidase in human pulmonary artery smooth muscle cells
Q37461694Hyaluronic Acid Promotes Angiogenesis by Inducing RHAMM-TGFβ Receptor Interaction via CD44-PKCδ
Q37849782Hydrogen peroxide as a signaling molecule
Q64377732Hydrogen peroxide produced by angiopoietin-1 mediates angiogenesis
Q38196405Hydrogen peroxide signaling in vascular endothelial cells.
Q39485361Hydrogen peroxide signaling mediates DHEA-induced vascular endothelial cell proliferation
Q38844323Hypoxia, mitochondrial dysfunction and synovial invasiveness in rheumatoid arthritis
Q64378699ICAM-1 induction by TNFalpha and IL-6 is mediated by distinct pathways via Rac in endothelial cells
Q53618817IQGAP1 mediates VE-cadherin-based cell-cell contacts and VEGF signaling at adherence junctions linked to angiogenesis
Q46716879IQGAP1 regulates reactive oxygen species-dependent endothelial cell migration through interacting with Nox2.
Q44951935IQGAP1, a novel vascular endothelial growth factor receptor binding protein, is involved in reactive oxygen species--dependent endothelial migration and proliferation.
Q39964836Identification of a rare subset of adipose tissue-resident progenitor cells, which express CD133 and TRPC3 as a VEGF-regulated Ca2+ entry channel.
Q36313378Impact of oxidized low density lipoprotein on vascular cells
Q37762813Impaired redox signaling and antioxidant gene expression in endothelial cells in diabetes: a role for mitochondria and the nuclear factor-E2-related factor 2-Kelch-like ECH-associated protein 1 defense pathway
Q38087157Importance of insulin resistance to vascular repair and regeneration
Q80838573Important role of Nox4 type NADPH oxidase in angiogenic responses in human microvascular endothelial cells in vitro
Q45190378In vivo expression of recombinant vascular endothelial growth factor in rabbit carotid artery increases production of superoxide anion
Q34527211Increased expression and activity of 12-lipoxygenase in oxygen-induced ischemic retinopathy and proliferative diabetic retinopathy: implications in retinal neovascularization
Q38293179Induction of hypoxia-inducible factor 1alpha gene expression by vascular endothelial growth factor
Q44436286Inflammation and vascular hypertrophy induced by angiotensin II: role of NADPH oxidase-derived reactive oxygen species independently of blood pressure elevation?
Q46001182Inhibiting the response to VEGF in diabetes.
Q35085027Inhibition of NAD(P)H oxidase activity blocks vascular endothelial growth factor overexpression and neovascularization during ischemic retinopathy.
Q54382604Inhibition of hypoxia-induced retinal neovascularization in mice with short hairpin RNA targeting Rac1, possibly via blockading redox signaling
Q44628537Inhibition of vascular endothelial growth factor-induced angiogenesis by resveratrol through interruption of Src-dependent vascular endothelial cadherin tyrosine phosphorylation.
Q45983209Inhibitory actions of bilberry anthocyanidins on angiogenesis.
Q52844300Insulin- and Growth Factor-Resistance Impairs Vascular Regeneration in Diabetes Mellitus
Q44477930Interactions of angiotensin II with NAD(P)H oxidase, oxidant stress and cardiovascular disease
Q50971853Interactive effects of homocysteine and copper on angiogenesis in porcine isolated saphenous vein
Q42973581Intracellular Ca2+ can compensate for the lack of NADPH oxidase-derived ROS in endothelial cells
Q38730377Intracellular cysteine oxidation is modulated by aquaporin-8-mediated hydrogen peroxide channeling in leukaemia cells.
Q36954247Involvement of NADPH oxidases in cardiac remodelling and heart failure.
Q40338844Involvement of phosphoinositide 3-kinase class IA (PI3K 110α) and NADPH oxidase 1 (NOX1) in regulation of vascular differentiation induced by vascular endothelial growth factor (VEGF) in mouse embryonic stem cells
Q40303320Ischemia induces nuclear NOX2 expression in cardiomyocytes and subsequently activates apoptosis
Q37690990Isoform specific functions of Nox protein-derived reactive oxygen species in the vasculature
Q48599380Lectin-like Oxidized Low-density Lipoprotein Receptor-1 (LOX-1) and Cardiac Fibroblast Growth
Q46793312Left ventricular remodeling after myocardial infarction in mice with targeted deletion of the NADPH oxidase subunit gp91PHOX.
Q61841565Leptin promotes the mobilization of vascular progenitor cells and neovascularization by NOX2-mediated activation of MMP9
Q37965449Less stress, more success? Oncological implications of surgery-induced oxidative stress.
Q36936487Localized cysteine sulfenic acid formation by vascular endothelial growth factor: role in endothelial cell migration and angiogenesis
Q36574300Localizing NADPH oxidase-derived ROS.
Q46656372Lung endothelial cell proliferation with decreased shear stress is mediated by reactive oxygen species
Q44890498Lysophosphatidylcholine-induced modulation of Ca(2+)-activated K(+)channels contributes to ROS-dependent proliferation of cultured human endothelial cells
Q46552044Mechanisms for suppressing NADPH oxidase in the vascular wall
Q46743727Methods in the evaluation of cardiovascular renin angiotensin aldosterone activation and oxidative stress
Q37322333Microglial ion channels as potential targets for neuroprotection in Parkinson's disease
Q46006832Microparticles from ischemic muscle promotes postnatal vasculogenesis.
Q44895732Microtubules regulate angiotensin II type 1 receptor and Rac1 localization in caveolae/lipid rafts: role in redox signaling
Q35103539Minodronate, a newly developed nitrogen-containing bisphosphonate, suppresses melanoma growth and improves survival in nude mice by blocking vascular endothelial growth factor signaling
Q91189456Mitochondrial dysfunction in rheumatoid arthritis: A comprehensive analysis by integrating gene expression, protein-protein interactions and gene ontology data
Q46432453Mitochondrial redox plays a critical role in the paradoxical effects of NAPDH oxidase-derived ROS on coronary endothelium.
Q33572306Molecular regulation of tumor angiogenesis and perfusion via redox signaling
Q54495622Monocyte chemotactic protein-induced protein (MCPIP) promotes inflammatory angiogenesis via sequential induction of oxidative stress, endoplasmic reticulum stress and autophagy
Q37076834Mouse models for preeclampsia: disruption of redox-regulated signaling
Q38521718Multi-layered representation for cell signaling pathways.
Q36311166Multifocal angiostatic therapy: an update
Q35624665N-terminal domain of soluble epoxide hydrolase negatively regulates the VEGF-mediated activation of endothelial nitric oxide synthase.
Q35761411NAD(P)H oxidase modulates angiogenesis and the development of portosystemic collaterals and splanchnic hyperaemia in portal hypertensive rats.
Q41554019NADPH Oxidase 4 Promotes Endothelial Angiogenesis Through Endothelial Nitric Oxide Synthase Activation
Q50297912NADPH oxidase 2 (NOX2) complex binds RAC1
Q39713250NADPH oxidase 4 mediates reactive oxygen species induction of CD146 dimerization in VEGF signal transduction.
Q28264121NADPH oxidase CYBA polymorphisms, oxidative stress and cardiovascular diseases
Q43292284NADPH oxidase Nox2 is required for hypoxia-induced mobilization of endothelial progenitor cells
Q46972328NADPH oxidase activity selectively modulates vascular endothelial growth factor signaling pathways
Q36232155NADPH oxidase and endothelial cell function
Q46065944NADPH oxidase isoform selective regulation of endothelial cell proliferation and survival.
Q36656609NADPH oxidase modulates myocardial Akt, ERK1/2 activation, and angiogenesis after hypoxia-reoxygenation
Q37449222NADPH oxidase signaling and cardiac myocyte function.
Q33632781NADPH oxidase, NOX1, mediates vascular injury in ischemic retinopathy
Q37265507NADPH oxidase-dependent signaling in endothelial cells: role in physiology and pathophysiology
Q41089726NADPH oxidase-derived overproduction of reactive oxygen species impairs postischemic neovascularization in mice with type 1 diabetes.
Q41786123NADPH oxidase-generated reactive oxygen species are required for stromal cell-derived factor-1α-stimulated angiogenesis
Q38054458NADPH oxidases as a source of oxidative stress and molecular target in ischemia/reperfusion injury
Q37974319NADPH oxidases as regulators of tumor angiogenesis: current and emerging concepts
Q37742824NADPH oxidases in cardiovascular disease.
Q35145985NADPH oxidases in cardiovascular disease: insights from in vivo models and clinical studies.
Q36505570NADPH oxidases in cardiovascular health and disease
Q36571169NADPH oxidases in lung biology and pathology: host defense enzymes, and more
Q33632089NADPH oxidases in vascular pathology
Q36302873NADPH oxidases: an overview from structure to innate immunity-associated pathologies
Q33739287NADPH oxidases: functions and pathologies in the vasculature
Q33649864NOX enzymes and pulmonary disease
Q40229689NOX2 and NOX4 mediate proliferative response in endothelial cells.
Q59128438NOX2 oxidase expressed in endosomes promotes cell proliferation and prostate tumour development
Q24295185NOX5 variants are functionally active in endothelial cells
Q35862506Neovascularization in an arterio-venous loop-containing tissue engineering chamber: role of NADPH oxidase
Q36230886New insights on oxidative stress in the artery wall.
Q36317506Nicotinamide adenine dinucleotide phosphate oxidase: a promiscuous therapeutic target for cardiovascular drugs?
Q34391024Novel role of ARF6 in vascular endothelial growth factor-induced signaling and angiogenesis
Q33649852Novel role of NADPH oxidase in angiogenesis and stem/progenitor cell function.
Q39261217Novel role of antioxidant-1 (Atox1) as a copper-dependent transcription factor involved in cell proliferation
Q35964916Novel role of p66Shc in ROS-dependent VEGF signaling and angiogenesis in endothelial cells
Q37852399Nox enzymes in allergic airway inflammation
Q38243365Nox family NADPH oxidases: Molecular mechanisms of activation
Q34577042Nox2 is required for macrophage chemotaxis towards CSF-1.
Q41268543Nox2 regulates endothelial cell cycle arrest and apoptosis via p21cip1 and p53
Q45941582Nox2-containing NADPH oxidase deficiency confers protection from hindlimb ischemia in conditions of increased oxidative stress.
Q34597540Nox4 NADPH oxidase-derived reactive oxygen species, via endogenous carbon monoxide, promote survival of brain endothelial cells during TNF-α-induced apoptosis
Q34264162Nox4 is a protective reactive oxygen species generating vascular NADPH oxidase
Q42177157Nox4- and Nox2-dependent oxidant production is required for VEGF-induced SERCA cysteine-674 S-glutathiolation and endothelial cell migration
Q35929722OKN-007 decreases VEGFR-2 levels in a preclinical GL261 mouse glioma model
Q79793883Optimal reactive oxygen species concentration and p38 MAP kinase are required for coronary collateral growth
Q31025245Overexpression of catalase in myeloid cells causes impaired postischemic neovascularization.
Q79346091Oxidant signaling in lung cells
Q36136532Oxidant stress in renal pathophysiology
Q54162627Oxidative damage in synovial tissue is associated with in vivo hypoxic status in the arthritic joint
Q36953696Oxidative stress impairs endothelial progenitor cell function
Q42589408Oxidative stress improves coronary endothelial function through activation of the pro-survival kinase AMPK.
Q37535220Oxidative stress in angiogenesis and vascular disease
Q34000654Oxidative stress promotes ocular neovascularization.
Q35903570Oxygen free radicals and redox biology of organelles
Q38208146Paradoxical action of reactive oxygen species in creation and therapy of cancer
Q35573957Pathophysiological aspects of cellular pyridine nucleotide metabolism: focus on the vascular endothelium. Review
Q36129229Pathophysiological basis for the prophylaxis of preeclampsia through early supplementation with antioxidant vitamins
Q37889557Pathophysiological roles of NADPH oxidase/nox family proteins in the vascular system. -Review and perspective-.
Q33599707Peripheral artery disease, redox signaling, oxidative stress - Basic and clinical aspects
Q46800337Peroxisome proliferator activated receptor gamma agonists suppress TNFalpha-induced ICAM-1 expression by endothelial cells in a manner potentially dependent on inhibition of reactive oxygen species
Q56742829Peroxynitrite mediates VEGF's angiogenic signal and function via a nitration-independent mechanism in endothelial cells
Q38931047Pharmacological Management Options to Prevent and Reduce Ischemic Hemorrhagic Transformation
Q46525971Pharmacological and genetic inhibition of NADPH oxidase does not reduce brain damage in different models of perinatal brain injury in newborn mice
Q46038701Phosphodiesterase 2 mediates redox-sensitive endothelial cell proliferation and angiogenesis by thrombin via Rac1 and NADPH oxidase 2.
Q46076554Pigment epithelium-derived factor (PEDF) inhibits survival and proliferation of VEGF-exposed multiple myeloma cells through its anti-oxidative properties
Q44711333Platelets induce reactive oxygen species-dependent growth of human skin fibroblasts
Q36248631Pleiotropic AT1 receptor signaling pathways mediating physiological and pathogenic actions of angiotensin II.
Q37077934Post-ischaemic neovascularization and inflammation
Q38153677Postischemic revascularization: from cellular and molecular mechanisms to clinical applications
Q43282978Probucol and antioxidant vitamins rescue ischemia-induced neovascularization in mice exposed to cigarette smoke: potential role of endothelial progenitor cells
Q33632180Proliferative diabetic retinopathy and relations among antioxidant activity, oxidative stress, and VEGF in the vitreous body.
Q47762178Protective Effect of Combined Caffeic Acid Phenethyl Ester and Bevacizumab Against Hydrogen Peroxide-Induced Oxidative Stress in Human RPE Cells
Q45785313Protein kinase C-delta mediates von Willebrand factor secretion from endothelial cells in response to vascular endothelial growth factor (VEGF) but not histamine
Q53573779Proteomic analysis of tyrosine phosphorylations in vascular endothelial growth factor- and reactive oxygen species-mediated signaling pathway
Q106518963RAC1 binds effectors at the plasma membrane
Q45318323RHO GTPases Activate NADPH Oxidases
Q28396460ROS, Notch, and Wnt signaling pathways: crosstalk between three major regulators of cardiovascular biology
Q44628944Rac and Rho play opposing roles in the regulation of hypoxia/reoxygenation-induced permeability changes in pulmonary artery endothelial cells
Q42489769Rac1 and RhoA as regulators of endothelial phenotype and barrier function in hypoxia-induced neonatal pulmonary hypertension
Q34197794Rac1-Dependent Intracellular Superoxide Formation Mediates Vascular Endothelial Growth Factor–Induced Placental Angiogenesis in Vitro
Q36368626Rapid actions of aldosterone in vascular health and disease--friend or foe?
Q50053776Reactive Oxygen Species Play a Biphasic Role in Brain Ischemia
Q45834311Reactive Oxygen Species and NOX Enzymes Are Emerging as Key Players in Cutaneous Wound Repair
Q60731459Reactive Oxygen Species in Physiologic and Pathologic Angiogenesis
Q36587602Reactive Oxygen Species in Vascular Formation and Development
Q36770038Reactive oxygen and nitrogen species: implications for cardiovascular device engineering
Q37135987Reactive oxygen species and angiogenesis: NADPH oxidase as target for cancer therapy
Q35845567Reactive oxygen species and angiotensin II signaling in vascular cells -- implications in cardiovascular disease
Q34757570Reactive oxygen species and endothelial activation
Q35949648Reactive oxygen species as mediators of angiogenesis signaling: role of NAD(P)H oxidase
Q36342607Reactive oxygen species as signaling molecules in cardiovascular differentiation of embryonic stem cells and tumor-induced angiogenesis
Q38122186Reactive oxygen species in cancer biology and anticancer therapy
Q35569201Reactive oxygen species in the vasculature: molecular and cellular mechanisms
Q36510294Reactive oxygen species in vascular endothelial cell motility. Roles of NAD(P)H oxidase and Rac1.
Q45931818Reactive oxygen species mediate compensatory glomerular hypertrophy in rat uninephrectomized kidney.
Q40267905Reactive oxygen species regulate insulin-induced VEGF and HIF-1alpha expression through the activation of p70S6K1 in human prostate cancer cells
Q34227711Reactive oxygen species regulate osteopontin expression in a murine model of postischemic neovascularization.
Q27332266Reactive oxygen species regulate protrusion efficiency by controlling actin dynamics
Q46903669Reactive oxygen species regulate the quiescence of CD34-positive cells derived from human embryonic stem cells
Q38078985Reactive oxygen species, Nox and angiotensin II in angiogenesis: implications for retinopathy
Q35888592Reactive oxygen species-mediated signal transduction in the endothelium
Q37721558Reactive oxygen species: A radical role in development?
Q38217380Reactive oxygen species: physiological roles in the regulation of vascular cells
Q37650551Receptor activation of NADPH oxidases
Q98474971Recruitment and Maturation of the Coronary Collateral Circulation: Current Understanding and Perspectives in Arteriogenesis
Q39059046Redox Control of Skeletal Muscle Regeneration.
Q37860340Redox Control of the Survival of Healthy and Diseased Cells
Q96836073Redox Regulation of NOX Isoforms on FAK(Y397)/SRC(Y416) Phosphorylation Driven Epithelial-to-Mesenchymal Transition in Malignant Cervical Epithelial Cells
Q27004547Redox balance dynamically regulates vascular growth and remodeling
Q40450443Redox control of angiogenic factors and CD31-positive vessel-like structures in mouse embryonic stem cells after direct current electrical field stimulation.
Q37245109Redox control of endothelial function and dysfunction: molecular mechanisms and therapeutic opportunities.
Q34298394Redox regulation of cancer cell migration and invasion
Q35889032Redox regulation of cell migration and adhesion
Q39256530Redox regulation of gasotransmission in the vascular system: A focus on angiogenesis
Q35174581Redox regulation of protein kinases
Q37055806Redox regulation of the VEGF signaling path and tissue vascularization: Hydrogen peroxide, the common link between physical exercise and cutaneous wound healing
Q36509981Redox signaling in angiogenesis: role of NADPH oxidase
Q93227644Redox signaling in the pathogenesis of human disease and the regulatory role of autophagy
Q36628663Redox signalling involving NADPH oxidase-derived reactive oxygen species
Q37076810Redox signals in wound healing
Q40229694Redox-dependent expression of cyclin D1 and cell proliferation by Nox1 in mouse lung epithelial cells
Q33765463Redox-dependent mechanisms in coronary collateral growth: the "redox window" hypothesis
Q35608868Redox-dependent signalling by angiotensin II and vascular remodelling in hypertension
Q46468624Reducing oxidized lipids to prevent cardiovascular disease
Q33772560Regulation of NADPH oxidase in vascular endothelium: the role of phospholipases, protein kinases, and cytoskeletal proteins
Q36412266Regulation of NADPH oxidases: the role of Rac proteins
Q37414487Regulation of cell proliferation by NADPH oxidase-mediated signaling: potential roles in tissue repair, regenerative medicine and tissue engineering
Q37826870Regulation of myocardial growth and death by NADPH oxidase
Q35651532Relationship between expression of NADPH oxidase 2 and invasion and prognosis of human gastric cancer
Q79460195Resveratrol attenuates oxLDL-stimulated NADPH oxidase activity and protects endothelial cells from oxidative functional damages
Q36097870Resveratrol: preventing properties against vascular alterations and ageing
Q33641986Role of NADPH oxidase and Stat3 in statin-mediated protection against diabetic retinopathy.
Q46411412Role of NADPH oxidase in tissue growth in a tissue engineering chamber in rats
Q35895542Role of autophagy in angiogenesis in aortic endothelial cells
Q31167736Role of gp91phox (Nox2)-containing NAD(P)H oxidase in angiogenesis in response to hindlimb ischemia.
Q37691607Role of metabolic H2O2 generation: redox signaling and oxidative stress
Q42535142Role of nox2-based NADPH oxidase in bone marrow and progenitor cell function involved in neovascularization induced by hindlimb ischemia
Q29617974Role of oxidative modifications in atherosclerosis
Q37045445Role of oxidative stress and nitric oxide in atherothrombosis
Q42199994Role of protein tyrosine phosphatase 1B in vascular endothelial growth factor signaling and cell-cell adhesions in endothelial cells
Q35572612Role of reactive oxygen species in vascular remodeling associated with pulmonary hypertension
Q42481813Roles of reactive oxygen species in angiopoietin-1/tie-2 receptor signaling.
Q85071634Rosiglitazone, a PPAR-γ agonist, inhibits VEGF secretion by peripheral blood mononuclear cells and ROS production by human leukocytes
Q54493403S-Glutathionylation of LMW-PTP regulates VEGF-mediated FAK activation and endothelial cell migration
Q39700512S1P1 and VEGFR-2 form a signaling complex with extracellularly regulated kinase 1/2 and protein kinase C-alpha regulating ML-1 thyroid carcinoma cell migration
Q46129058SLC7A11 Overexpression in Glioblastoma Is Associated with Increased Cancer Stem Cell-Like Properties
Q37313563Selective targeting of NADPH oxidase for cardiovascular protection
Q46590490Senescence marker protein-30 deficiency impairs angiogenesis under ischemia
Q37094609Signal cross talks for sustained MAPK activation and cell migration: the potential role of reactive oxygen species
Q92204043Skeletal muscle-derived exosomes regulate endothelial cell functions via reactive oxygen species-activated nuclear factor-κB signalling
Q80838580Small concentrations of oxLDL induce capillary tube formation from endothelial cells via LOX-1-dependent redox-sensitive pathway
Q36118494Specificity in reactive oxidant signaling: think globally, act locally
Q28576634Sphingosine 1-phosphate transactivates the platelet-derived growth factor beta receptor and epidermal growth factor receptor in vascular smooth muscle cells
Q36320521Subcellular targeting of oxidants during endothelial cell migration
Q37394541Superoxide dismutase1 levels in North Indian population with age-related macular degeneration
Q37138949Suppressed hindlimb perfusion in Rac2-/- and Nox2-/- mice does not result from impaired collateral growth
Q35888581Suppression of oxidative stress in the endothelium and vascular wall
Q46425143TFEB inhibits endothelial cell inflammation and reduces atherosclerosis
Q50658306TNF-alpha potentiates protein-tyrosine nitration through activation of NADPH oxidase and eNOS localized in membrane rafts and caveolae of bovine aortic endothelial cells
Q36398049Targeting reactive oxygen species in hypertension
Q37781872Targeting tissue oxidative damage by means of cell signaling modulators: The antioxidant concept revisited
Q28743072Targeting vascular NADPH oxidase 1 blocks tumor angiogenesis through a PPARα mediated mechanism
Q28304274The A930G polymorphism ofP22phox (CYBA) gene but not C242T variation is associated with hypertension: a meta-analysis
Q52331695The Antioxidant Therapy: New Insights in the Treatment of Hypertension.
Q83594973The HIF1 target geneNOX2promotes angiogenesis through urotensin-II
Q39306993The Importance of NADPH Oxidases and Redox Signaling in Angiogenesis.
Q53659763The NADPH Oxidase Nox4 mediates tumour angiogenesis
Q27860991The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology
Q39028636The Pathophysiological Role of NOX2 in Hypertension and Organ Damage
Q26741231The Potential Role of Kallistatin in the Development of Abdominal Aortic Aneurysm
Q104102211The Protective Effects of Peroxisome Proliferator-Activated Receptor Gamma in Cerebral Ischemia-Reperfusion Injury
Q104488857The Relationship Between Reactive Oxygen Species and Endothelial Cell Metabolism
Q38151364The Yin and Yang of redox regulation.
Q36931118The albino mutation of tyrosinase alters ocular angiogenic responsiveness
Q54540532The anti-angiogenic and anti-tumor activity of synthetic phenylpropenone derivatives is mediated through the inhibition of receptor tyrosine kinases
Q46207244The anti-angiogenic effects of 1-furan-2-yl-3-pyridin-2-yl-propenone are mediated through the suppression of both VEGF production and VEGF-induced signaling
Q36501615The expanding role of NADPH oxidases in health and disease: no longer just agents of death and destruction
Q31145053The expression of the NADPH oxidase subunit p22phox is regulated by a redox-sensitive pathway in endothelial cells
Q34276805The general case for redox control of wound repair
Q53381128The multi-kinase inhibitor pazopanib targets hepatic stellate cell activation and apoptosis alleviating progression of liver fibrosis
Q37377623The regulation of vascular endothelial growth factor-induced microvascular permeability requires Rac and reactive oxygen species
Q46913012The regulatory effect of norepinephrine on connective tissue growth factor (CTGF) and vascular endothelial growth factor (VEGF) expression in cultured cardiac fibroblasts
Q46489830The role of reactive oxygen species in TNFalpha-dependent expression of the receptor for advanced glycation end products in human umbilical vein endothelial cells
Q40422869The tyrosine phosphatase, SHP-1, is a negative regulator of endothelial superoxide formation
Q30824712The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases
Q84260009Thioredoxin-interacting protein mediates TRX1 translocation to the plasma membrane in response to tumor necrosis factor-α: a key mechanism for vascular endothelial growth factor receptor-2 transactivation by reactive oxygen species
Q28586447Tks5-dependent, nox-mediated generation of reactive oxygen species is necessary for invadopodia formation
Q35867960Transforming growth factor-β1 requires NADPH oxidase 4 for angiogenesis in vitro and in vivo
Q43274985Troglitazone inhibits vascular endothelial growth factor-induced angiogenic signaling via suppression of reactive oxygen species production and extracellular signal-regulated kinase phosphorylation in endothelial cells
Q38205041Understanding the biology of reactive oxygen species and their link to cancer: NADPH oxidases as novel pharmacological targets.
Q35159432Unforeseen decreases in dissolved oxygen levels affect tube formation kinetics in collagen gels
Q40290581Upregulation of Id-1 via BMP-2 receptors induces reactive oxygen species in podocytes
Q36825904VEGF signaling through NADPH oxidase-derived ROS.
Q36450466VEGFR-2 inhibition augments cigarette smoke-induced oxidative stress and inflammatory responses leading to endothelial dysfunction
Q42009141Vaccinium myrtillus (Bilberry) Extracts Reduce Angiogenesis In Vitro and In Vivo
Q35175526Vascular NAD(P)H oxidases: specific features, expression, and regulation
Q35994483Vascular NADPH oxidases: molecular mechanisms of activation.
Q34280300Vascular endothelial growth factor and diabetic retinopathy: pathophysiological mechanisms and treatment perspectives.
Q33219756Vascular endothelial growth factor and diabetic retinopathy: role of oxidative stress
Q30961526Vascular endothelial growth factor causes translocation of p47phox to membrane ruffles through WAVE1.
Q36929380Vascular endothelial growth factor in eye disease
Q40526010Vascular endothelial growth factor-mediated induction of manganese superoxide dismutase occurs through redox-dependent regulation of forkhead and IkappaB/NF-kappaB.
Q33112683Vasculostatin, a proteolytic fragment of brain angiogenesis inhibitor 1, is an antiangiogenic and antitumorigenic factor
Q35950277Vasoactive factors and diabetic retinopathy: vascular endothelial growth factor, cycoloxygenase-2 and nitric oxide
Q24316420Xanthine oxidase interaction with vascular endothelial growth factor in human endothelial cell angiogenesis
Q87820292[ROS and NADPH oxidase: key regulators of tumor vascularisation]
Q44478660c-Src and smooth muscle NAD(P)H oxidase: assembling a path to hypertrophy
Q36302954eNOS overexpression exacerbates vascular closure in the obliterative phase of OIR and increases angiogenic drive in the subsequent proliferative stage

Search more.