| scholarly article | Q13442814 |
| P819 | ADS bibcode | 1994PNAS...9110650L |
| P356 | DOI | 10.1073/PNAS.91.22.10650 |
| P932 | PMC publication ID | 45079 |
| P698 | PubMed publication ID | 7938008 |
| P5875 | ResearchGate publication ID | 15261245 |
| P2093 | author name string | T L Leto | |
| A G Adams | |||
| I de Mendez | |||
| P2860 | cites work | Cloning of a 67-kD neutrophil oxidase factor with similarity to a noncatalytic region of p60c-src | Q24300397 |
| Recombinant 47-kilodalton cytosol factor restores NADPH oxidase in chronic granulomatous disease | Q24308107 | ||
| Cloning of the cDNA and functional expression of the 47-kilodalton cytosolic component of human neutrophil respiratory burst oxidase | Q24310083 | ||
| Csk inhibition of c-Src activity requires both the SH2 and SH3 domains of Src | Q24310206 | ||
| Point mutation in the cytoplasmic domain of the neutrophil p22-phox cytochrome b subunit is associated with a nonfunctional NADPH oxidase and chronic granulomatous disease | Q24319232 | ||
| Primary structure and unique expression of the 22-kilodalton light chain of human neutrophil cytochrome b | Q24650898 | ||
| Identification of a protein that binds to the SH3 region of Abl and is similar to Bcr and GAP-rho | Q28187867 | ||
| Regulation of the superoxide-generating NADPH oxidase by a small GTP-binding protein and its stimulatory and inhibitory GDP/GTP exchange proteins | Q28210380 | ||
| Identification of a ten-amino acid proline-rich SH3 binding site | Q28266446 | ||
| Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling | Q28268458 | ||
| Regulation of the human neutrophil NADPH oxidase by rho-related G-proteins | Q28269651 | ||
| Cloning the gene for an inherited human disorder--chronic granulomatous disease--on the basis of its chromosomal location | Q28302293 | ||
| Cloning and functional expression of the mouse homologue of p47phox | Q28510779 | ||
| The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1 | Q28511655 | ||
| Regulation of phagocyte oxygen radical production by the GTP-binding protein Rac 2 | Q28609631 | ||
| The GTPase dynamin binds to and is activated by a subset of SH3 domains | Q29618141 | ||
| SH2 and SH3 domains: from structure to function | Q29620259 | ||
| Structural basis for the binding of proline-rich peptides to SH3 domains | Q29620408 | ||
| Role of p67-phox SH3 domains in assembly of the NADPH oxidase system | Q30194267 | ||
| Signalling through SH2 and SH3 domains | Q30195158 | ||
| Two cytosolic components of the human neutrophil respiratory burst oxidase translocate to the plasma membrane during cell activation | Q34244747 | ||
| Neutrophil nicotinamide adenine dinucleotide phosphate oxidase assembly. Translocation of p47-phox and p67-phox requires interaction between p47-phox and cytochrome b558. | Q40339903 | ||
| Cytochrome b558: the flavin-binding component of the phagocyte NADPH oxidase. | Q41620128 | ||
| Phosphorylation of neutrophil 47-kDa cytosolic oxidase factor. Translocation to membrane is associated with distinct phosphorylation events. | Q44581701 | ||
| Characterization of neutrophil NADPH oxidase factors p47-phox and p67-phox from recombinant baculoviruses. | Q52447388 | ||
| Evidence for a functional cytoplasmic domain of phagocyte oxidase cytochrome b558 | Q57908472 | ||
| Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1 | Q59053220 | ||
| Direct evidence for interaction between COOH-terminal regions of cytochrome b558 subunits and cytosolic 47-kDa protein during activation of an O(2-)-generating system in neutrophils | Q67860054 | ||
| Reconstitution of neutrophil NADPH oxidase activity in the cell-free system by four components: p67-phox, p47-phox, p21rac1, and cytochrome b-245 | Q68027439 | ||
| P433 | issue | 22 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | respiratory burst | Q838181 |
| Neutrophil cytosolic factor 1 | Q21104738 | ||
| cytochrome b-245 alpha chain | Q21109992 | ||
| Neutrophil cytosolic factor 2 | Q21114554 | ||
| P304 | page(s) | 10650-4 | |
| P577 | publication date | 1994-10-25 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Assembly of the phagocyte NADPH oxidase: binding of Src homology 3 domains to proline-rich targets | |
| P478 | volume | 91 |
| Q36685379 | A domain of p47phox that interacts with human neutrophil flavocytochrome b558. |
| Q24314359 | A fluorescently tagged C-terminal fragment of p47phox detects NADPH oxidase dynamics during phagocytosis |
| Q44512445 | A new role of Pro-73 of p47phox in the activation of neutrophil NADPH oxidase |
| Q44283104 | A novel assay system implicates PtdIns(3,4)P(2), PtdIns(3)P, and PKC delta in intracellular production of reactive oxygen species by the NADPH oxidase |
| Q33698833 | A novel protein kinase target for the lipid second messenger phosphatidic acid |
| Q24561483 | A p47-phox pseudogene carries the most common mutation causing p47-phox- deficient chronic granulomatous disease |
| Q34055834 | A prenylated p47phox-p67phox-Rac1 chimera is a Quintessential NADPH oxidase activator: membrane association and functional capacity |
| Q43918747 | A prenylated p67phox-Rac1 chimera elicits NADPH-dependent superoxide production by phagocyte membranes in the absence of an activator and of p47phox: conversion of a pagan NADPH oxidase to monotheism |
| Q24296133 | A region C-terminal to the proline-rich core of p47phox regulates activation of the phagocyte NADPH oxidase by interacting with the C-terminal SH3 domain of p67phox |
| Q30478913 | A regulated adaptor function of p40phox: distinct p67phox membrane targeting by p40phox and by p47phox |
| Q28297425 | Activation and assembly of the NADPH oxidase: a structural perspective |
| Q24308874 | Activation of extracellular signal-regulated kinase 2 by a novel Abl-binding protein, ST5 |
| Q30175411 | Activation of the phagocyte NADPH oxidase protein p47(phox). Phosphorylation controls SH3 domain-dependent binding to p22(phox). |
| Q24303790 | Activation of the superoxide-producing phagocyte NADPH oxidase requires co-operation between the tandem SH3 domains of p47phox in recognition of a polyproline type II helix and an adjacent alpha-helix of p22phox |
| Q28266522 | Analysis of human phagocyte flavocytochrome b(558) by mass spectrometry |
| Q30176265 | Anionic amphiphile-independent activation of the phagocyte NADPH oxidase in a cell-free system by p47phox and p67phox, both in C terminally truncated forms. Implication for regulatory Src homology 3 domain-mediated interactions. |
| Q30175140 | Arachidonic acid and phosphorylation synergistically induce a conformational change of p47phox to activate the phagocyte NADPH oxidase |
| Q34138960 | Arachidonic acid induces direct interaction of the p67(phox)-Rac complex with the phagocyte oxidase Nox2, leading to superoxide production |
| Q28215817 | Architecture of the p40-p47-p67phox complex in the resting state of the NADPH oxidase. A central role for p67phox |
| Q30176829 | Assembly and activation of the phagocyte NADPH oxidase. Specific interaction of the N-terminal Src homology 3 domain of p47phox with p22phox is required for activation of the NADPH oxidase |
| Q30176886 | Assembly of the human neutrophil NADPH oxidase involves binding of p67phox and flavocytochrome b to a common functional domain in p47phox. |
| Q44854788 | Binding of FAD to cytochrome b558 is facilitated during activation of the phagocyte NADPH oxidase, leading to superoxide production |
| Q24307993 | Binding of the PX domain of p47(phox) to phosphatidylinositol 3,4-bisphosphate and phosphatidic acid is masked by an intramolecular interaction |
| Q26991619 | Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system |
| Q38799163 | CYBA encoding p22(phox), the cytochrome b558 alpha polypeptide: gene structure, expression, role and physiopathology |
| Q51747985 | Carcinogenesis and Reactive Oxygen Species Signaling: Interaction of the NADPH Oxidase NOX1-5 and Superoxide Dismutase 1-3 Signal Transduction Pathways. |
| Q35992729 | Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets |
| Q35562465 | Cooperation of p40(phox) with p47(phox) for Nox2-based NADPH oxidase activation during Fcγ receptor (FcγR)-mediated phagocytosis: mechanism for acquisition of p40(phox) phosphatidylinositol 3-phosphate (PI(3)P) binding |
| Q45246489 | Crucial role of two potential cytosolic regions of Nox2, 191TSSTKTIRRS200 and 484DESQANHFAVHHDEEKD500, on NADPH oxidase activation |
| Q28273527 | Cryptic Rac-binding and p21(Cdc42Hs/Rac)-activated kinase phosphorylation sites of NADPH oxidase component p67(phox) |
| Q39944302 | Cytosolic phospholipase A2alpha is targeted to the p47phox-PX domain of the assembled NADPH oxidase via a novel binding site in its C2 domain |
| Q28256579 | Deletion mutagenesis of p22phox subunit of flavocytochrome b558: identification of regions critical for gp91phox maturation and NADPH oxidase activity |
| Q45345920 | Direct involvement of the small GTPase Rac in activation of the superoxide-producing NADPH oxidase Nox1. |
| Q30177046 | Distinct ligand preferences of Src homology 3 domains from Src, Yes, Abl, Cortactin, p53bp2, PLCgamma, Crk, and Grb2. |
| Q44854782 | Distinct ligand-dependent roles for p38 MAPK in priming and activation of the neutrophil NADPH oxidase |
| Q36059818 | Ebselen and congeners inhibit NADPH oxidase 2-dependent superoxide generation by interrupting the binding of regulatory subunits |
| Q24537198 | Effects of Anaplasma phagocytophila on NADPH oxidase components in human neutrophils and HL-60 cells |
| Q24338397 | Effects of p47phox C terminus phosphorylations on binding interactions with p40phox and p67phox. Structural and functional comparison of p40phox and p67phox SH3 domains |
| Q51710433 | Exploring the arachidonic acid-induced structural changes in phagocyte NADPH oxidase p47(phox) and p67(phox) via thiol accessibility and SRCD spectroscopy. |
| Q27643779 | Full-length p40phox structure suggests a basis for regulation mechanism of its membrane binding |
| Q35743968 | Functional pseudogenes inhibit the superoxide production. |
| Q34146538 | Fungal metabolite gliotoxin inhibits assembly of the human respiratory burst NADPH oxidase |
| Q33558138 | Fungal metabolite gliotoxin targets flavocytochrome b558 in the activation of the human neutrophil NADPH oxidase |
| Q43595422 | Fused p47phox and p67phox truncations efficiently reconstitute NADPH oxidase with higher activity and stability than the individual components |
| Q33265631 | Gene transfer and expression in human neutrophils. The phox homology domain of p47phox translocates to the plasma membrane but not to the membrane of mature phagosomes |
| Q73206072 | How Src exercises self-restraint |
| Q40503847 | Hypothalamic proline-rich polypeptide is an oxidative burst regulator |
| Q30193003 | Identification of Acan125 as a Myosin-I-binding Protein Present with Myosin-I on Cellular Organelles of Acanthamoeba |
| Q24299772 | Identification of an actin-binding site in p47phox an organizer protein of NADPH oxidase |
| Q37069112 | Impaired priming and activation of the neutrophil NADPH oxidase in patients with IRAK4 or NEMO deficiency |
| Q43074613 | Inhibition of human vascular NADPH oxidase by apocynin derived oligophenols |
| Q41838897 | Interaction of human neutrophil flavocytochrome b with cytosolic proteins: transferred-NOESY NMR studies of a gp91phox C-terminal peptide bound to p47phox. |
| Q30176188 | Interaction of two proline-rich sequences of cell adhesion kinase beta with SH3 domains of p130Cas-related proteins and a GTPase-activating protein, Graf |
| Q30176875 | Interactions between cytosolic components of the NADPH oxidase: p40phox interacts with both p67phox and p47phox |
| Q30175978 | Intersectin, a novel adaptor protein with two Eps15 homology and five Src homology 3 domains. |
| Q24548021 | Involvement of Rac1 in activation of multicomponent Nox1- and Nox3-based NADPH oxidases |
| Q30176831 | Involvement of p40phox in activation of phagocyte NADPH oxidase through association of its carboxyl-terminal, but not its amino-terminal, with p67phox |
| Q30661660 | JFC1, a novel tandem C2 domain-containing protein associated with the leukocyte NADPH oxidase. |
| Q30176152 | Mapping of functional domains in p47(phox) involved in the activation of NADPH oxidase by "peptide walking". |
| Q24291961 | Mapping of functional domains in the p22(phox) subunit of flavocytochrome b(559) participating in the assembly of the NADPH oxidase complex by "peptide walking" |
| Q34104041 | Mapping sites of interaction of p47-phox and flavocytochrome b with random-sequence peptide phage display libraries |
| Q30193582 | Mapping the domains of interaction of p40phox with both p47phox and p67phox of the neutrophil oxidase complex using the two-hybrid system. |
| Q30175408 | Membrane-targeting of signalling molecules by SH2/SH3 domain-containing adaptor proteins |
| Q27641143 | Molecular basis of phosphorylation-induced activation of the NADPH oxidase |
| Q33300608 | Molecular evolution of Phox-related regulatory subunits for NADPH oxidase enzymes |
| Q30177020 | Multiple SH3 domain interactions regulate NADPH oxidase assembly in whole cells |
| Q40963048 | Mutagenesis of an arginine- and lysine-rich domain in the gp91(phox) subunit of the phagocyte NADPH-oxidase flavocytochrome b558. |
| Q24298671 | Mutagenesis of p22(phox) histidine 94. A histidine in this position is not required for flavocytochrome b558 function |
| Q63365800 | NADH/NADPH Oxidase and Vascular Function |
| Q64281039 | NADPH oxidase 2 inhibitors CPP11G and CPP11H attenuate endothelial cell inflammation & vessel dysfunction and restore mouse hind-limb flow |
| Q30176826 | NADPH oxidase activity is independent of p47phox in vitro |
| Q24297967 | NMR solution structure of the tandem Src homology 3 domains of p47phox complexed with a p22phox-derived proline-rich peptide |
| Q28367777 | Naphthalenesulphonamides block neutrophil superoxide production by intact cells and in a cell-free system: is myosin light chain kinase responsible for these effects? |
| Q27024628 | Neutrophils in innate host defense against Staphylococcus aureus infections |
| Q24300616 | Novel Human Homologues of p47 and p67 Participate in Activation of Superoxide-producing NADPH Oxidases |
| Q41468408 | Oxidative burst: an early plant response to pathogen infection |
| Q37568472 | PR-39, a proline-rich antibacterial peptide that inhibits phagocyte NADPH oxidase activity by binding to Src homology 3 domains of p47 phox |
| Q30940086 | Phage display epitope mapping of human neutrophil flavocytochrome b558. Identification of two juxtaposed extracellular domains |
| Q36627802 | Phagocytosis-coupled activation of the superoxide-producing phagocyte oxidase, a member of the NADPH oxidase (nox) family |
| Q43509914 | Phosphatidic acid regulates tyrosine phosphorylating activity in human neutrophils: enhancement of Fgr activity |
| Q48684065 | Phosphatidic acid-mediated phosphorylation of the NADPH oxidase component p47-phox. Evidence that phosphatidic acid may activate a novel protein kinase. |
| Q37261114 | Phosphorylation of Nox1 regulates association with NoxA1 activation domain. |
| Q24681540 | Phosphorylation of p47phox directs phox homology domain from SH3 domain toward phosphoinositides, leading to phagocyte NADPH oxidase activation |
| Q34430784 | Point mutations in the proline-rich region of p22phox are dominant inhibitors of Nox1- and Nox2-dependent reactive oxygen generation. |
| Q30429784 | Probing the role of the carboxyl terminus of the gp91phox subunit of neutrophil flavocytochrome b558 using site-directed mutagenesis |
| Q73135106 | Race-specific elicitors of Cladosporium fulvum promote translocation of cytosolic components of NADPH oxidase to the plasma membrane of tomato cells |
| Q37446110 | Redox signaling in cardiovascular health and disease. |
| Q30156868 | Regulation of NOXO1 activity through reversible interactions with p22 and NOXA1. |
| Q37461363 | Regulation of reactive oxygen species generation in cell signaling |
| Q36666637 | Regulation of smooth muscle by inducible nitric oxide synthase and NADPH oxidase in vascular proliferative diseases |
| Q30163832 | Regulation of the NADPH-oxidase complex of phagocytic leukocytes. Recent insights from structural biology, molecular genetics, and microscopy |
| Q37766094 | Role of Reactive Oxygen Species in Tumor Necrosis Factor-alpha Induced Endothelial Dysfunction |
| Q30193848 | SH3-dependent assembly of the phagocyte NADPH oxidase |
| Q30495822 | SHIP-1 increases early oxidative burst and regulates phagosome maturation in macrophages |
| Q44949228 | Sequence-specific resonance assignments of the tandem SH3 domains in an autoinhibitory form of p47(phox). |
| Q30164100 | Solution structure of the tandem Src homology 3 domains of p47phox in an autoinhibited form |
| Q30176592 | Specificity of p47phox SH3 domain interactions in NADPH oxidase assembly and activation |
| Q42160318 | Spermine suppresses the activation of human neutrophil NADPH oxidase in cell-free and semi-recombinant systems |
| Q28282131 | Structure, regulation and evolution of Nox-family NADPH oxidases that produce reactive oxygen species |
| Q33217673 | Superoxide production in Galleria mellonella hemocytes: identification of proteins homologous to the NADPH oxidase complex of human neutrophils |
| Q30491877 | Targeting and regulation of reactive oxygen species generation by Nox family NADPH oxidases |
| Q28609613 | Tetratricopeptide repeat (TPR) motifs of p67(phox) participate in interaction with the small GTPase Rac and activation of the phagocyte NADPH oxidase |
| Q33213948 | The NADPH oxidase Nox3 constitutively produces superoxide in a p22phox-dependent manner: its regulation by oxidase organizers and activators |
| Q40410144 | The NADPH oxidase complex of phagocytic leukocytes: a biochemical and cytochemical view |
| Q47687992 | The NADPH oxidase of phagocytic leukocytes |
| Q35828194 | The NADPH oxidase of professional phagocytes--prototype of the NOX electron transport chain systems |
| Q30165057 | The adaptor protein p40(phox) as a positive regulator of the superoxide-producing phagocyte oxidase. |
| Q24291846 | The crystal structure of the PX domain from p40(phox) bound to phosphatidylinositol 3-phosphate |
| Q45887694 | The molecular basis of chronic granulomatous disease |
| Q28504676 | The p47phox mouse knock-out model of chronic granulomatous disease |
| Q27932963 | The phox homology (PX) domain protein interaction network in yeast |
| Q33573909 | The role of NADPH oxidase in a mouse model of fetal alcohol syndrome |
| Q28242255 | Three common polymorphisms in the CYBA gene form a haplotype associated with decreased ROS generation |
| Q35083719 | Transplasma membrane electron transport: enzymes involved and biological function. |
| Q30157954 | Tripartite chimeras comprising functional domains derived from the cytosolic NADPH oxidase components p47phox, p67phox, and Rac1 elicit activator-independent superoxide production by phagocyte membranes: an essential role for anionic membrane phosph |
| Q22004258 | Two isoforms of a human intersectin (ITSN) protein are produced by brain-specific alternative splicing in a stop codon |
| Q36325071 | Unique targeting of cytosolic phospholipase A2 to plasma membranes mediated by the NADPH oxidase in phagocytes |
| Q28306699 | p40(phox) down-regulates NADPH oxidase activity through interactions with its SH3 domain |
| Q30497179 | p47phox Phox homology domain regulates plasma membrane but not phagosome neutrophil NADPH oxidase activation |
| Q30156808 | p47phox molecular activation for assembly of the neutrophil NADPH oxidase complex |
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