The role of NADPH oxidase 1-derived reactive oxygen species in paraquat-mediated dopaminergic cell death

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The role of NADPH oxidase 1-derived reactive oxygen species in paraquat-mediated dopaminergic cell death is …
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scholarly articleQ13442814

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P356DOI10.1089/ARS.2009.2459
P8608Fatcat IDrelease_kjxwkh2yivfzlhcifrklkybpvy
P932PMC publication ID2935343
P698PubMed publication ID19450058

P50authorM. Flint BealQ67409129
P2093author name stringYoon-Seong Kim
Dong-Hee Choi
Ana Clara Cristóvão
Graça Baltazar
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Reduced and oxidized glutathione in the substantia nigra of patients with Parkinson's diseaseQ28317593
Immunohistochemical study of p47Phox and gp91Phox distributions in rat brainQ28564761
Oxidative stress in Parkinson's diseaseQ29618017
NADPH oxidases of the brain: distribution, regulation, and functionQ31061677
Mitochondria, oxidative damage, and inflammation in Parkinson's diseaseQ34212155
Critical role for microglial NADPH oxidase in rotenone-induced degeneration of dopaminergic neurons.Q34214876
Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor toneQ34378188
Ketamine-induced loss of phenotype of fast-spiking interneurons is mediated by NADPH-oxidaseQ34722527
Current molecular models for NADPH oxidase regulation by Rac GTPaseQ34915029
Mitochondria are a major source of paraquat-induced reactive oxygen species production in the brainQ34936383
Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neuronsQ35786982
Microglial activation as a priming event leading to paraquat-induced dopaminergic cell degenerationQ36026636
Synaptic localization of a functional NADPH oxidase in the mouse hippocampusQ36051340
Cytotoxicity of paraquat in microglial cells: Involvement of PKCdelta- and ERK1/2-dependent NADPH oxidaseQ36156588
Pharmacological inhibition of neuronal NADPH oxidase protects against 1-methyl-4-phenylpyridinium (MPP+)-induced oxidative stress and apoptosis in mesencephalic dopaminergic neuronal cellsQ36275187
A generalised increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease.Q36880536
Role of reactive oxygen species in the neurotoxicity of environmental agents implicated in Parkinson's diseaseQ37110410
Classical inhibitors of NOX NAD(P)H oxidases are not specific.Q37294085
Parkinson's disease: a case-control study of occupational and environmental risk factors.Q39102287
Free radical mediated cell toxicity by redox cycling chemicalsQ39137970
Oxidative pathways for catecholamines in the genesis of neuromelanin and cytotoxic quinonesQ39615110
The AP-1 site is essential for the promoter activity of NOX1/NADPH oxidase, a vascular superoxide-producing enzyme: Possible involvement of the ERK1/2-JunB pathwayQ39959652
Apocynin is not an inhibitor of vascular NADPH oxidases but an antioxidant.Q40034272
Rac1-NADPH oxidase-regulated generation of reactive oxygen species mediates glutamate-induced apoptosis in SH-SY5Y human neuroblastoma cellsQ40349340
Cross talk between mitochondria and superoxide generating NADPH oxidase in breast and ovarian tumorsQ40350108
Paraquat neurotoxicity is distinct from that of MPTP and rotenone.Q40377576
Superoxide dismutase/catalase mimetics are neuroprotective against selective paraquat-mediated dopaminergic neuron death in the substantial nigra: implications for Parkinson diseaseQ40411589
PKCdelta mediates up-regulation of NOX1, a catalytic subunit of NADPH oxidase, via transactivation of the EGF receptor: possible involvement of PKCdelta in vascular hypertrophyQ40418087
Parkinson's disease: a disorder due to nigral glutathione deficiency?Q41628096
Iron in the basal ganglia in Parkinson's disease. An in vitro study using extended X-ray absorption fine structure and cryo-electron microscopyQ41632791
Apocynin improves outcome in experimental stroke with a narrow dose rangeQ42403010
Expression and modulation of an NADPH oxidase in mammalian astrocytes.Q42484955
Increased nigral iron content and alterations in other metal ions occurring in brain in Parkinson's diseaseQ43624453
Environmental risk factors and Parkinson's disease: a case-control study in TaiwanQ43699090
The herbicide paraquat causes up-regulation and aggregation of alpha-synuclein in mice: paraquat and alpha-synucleinQ43798526
Subcutaneous rotenone exposure causes highly selective dopaminergic degeneration and alpha-synuclein aggregation.Q44264439
NADPH oxidase immunoreactivity in the mouse brainQ44602831
Neurodegenerative diseases and oxidative stressQ44805871
Basal lipid peroxidation in substantia nigra is increased in Parkinson's diseaseQ44808814
Reactive oxygen species derived from NOX1/NADPH oxidase enhance inflammatory pain.Q46361361
Role of oxidative stress in paraquat-induced dopaminergic cell degeneration.Q46460372
P433issue9
P921main subjectdopamineQ170304
reactive oxygen speciesQ424361
cell deathQ2383867
P304page(s)2105-2118
P577publication date2009-09-01
P1433published inAntioxidants & Redox SignalingQ4775078
P1476titleThe role of NADPH oxidase 1-derived reactive oxygen species in paraquat-mediated dopaminergic cell death
P478volume11

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