Matrix metalloproteinase-3 causes dopaminergic neuronal death through Nox1-regenerated oxidative stress

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Matrix metalloproteinase-3 causes dopaminergic neuronal death through Nox1-regenerated oxidative stress is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2014PLoSO...9k5954C
P356DOI10.1371/JOURNAL.PONE.0115954
P932PMC publication ID4275264
P698PubMed publication ID25536219
P5875ResearchGate publication ID270005315

P50authorJongmin LeeQ64780550
P2093author name stringYoon-Seong Kim
Ji-Hye Kim
Dong-Hee Choi
Wahn Soo Choi
Joo-Ha Seo
P2860cites workLink between mitochondria and NADPH oxidase 1 isozyme for the sustained production of reactive oxygen species and cell deathQ79173774
A pivotal role of matrix metalloproteinase-3 activity in dopaminergic neuronal degeneration via microglial activationQ79372306
Caspase-9 activation and Apaf-1 cleavage by MMP-3Q85683786
Cross talk between mitochondria and superoxide generating NADPH oxidase in breast and ovarian tumorsQ40350108
Essential role of ATF-1 in induction of NOX1, a catalytic subunit of NADPH oxidase: involvement of mitochondrial respiratory chainQ40502963
Establishment and characterization of immortalized clonal cell lines from fetal rat mesencephalic tissueQ41445923
The superoxide-producing NAD(P)H oxidase Nox4 in the nucleus of human vascular endothelial cellsQ42487257
Matrix metalloproteinase-3 contributes to vulnerability of the nigral dopaminergic neuronsQ43265011
Rapid isolation of metabolically active mitochondria from rat brain and subregions using Percoll density gradient centrifugationQ43950113
Increased myocardial NADPH oxidase activity in human heart failureQ44487850
NOXO1 phosphorylation on serine 154 is critical for optimal NADPH oxidase 1 assembly and activationQ44761796
Basal lipid peroxidation in substantia nigra is increased in Parkinson's diseaseQ44808814
Expression of MMP-2, MMP-9, and MMP-1 and their endogenous counterregulators TIMP-1 and TIMP-2 in postmortem brain tissue of Parkinson's diseaseQ48434967
Effects of apoE isoforms on beta-amyloid-induced matrix metalloproteinase-9 in rat astrocytesQ48443283
Analysis of functional polymorphisms of metalloproteinase genes in persons with vascular dementia and Alzheimer's disease.Q53282256
Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cellsQ63365807
Stereological estimates of number and length of capillaries in subdivisions of the human hippocampal regionQ77547566
Proteolytic cleavage of extracellular secreted {alpha}-synuclein via matrix metalloproteinasesQ24301116
DJ-1 Cleavage by Matrix Metalloproteinase 3 Mediates Oxidative Stress-Induced Dopaminergic Cell DeathQ24304197
SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS modelQ24307703
Increased alpha-synuclein aggregation following limited cleavage by certain matrix metalloproteinasesQ24316244
alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodiesQ24653247
The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiologyQ27860991
Novel role of NOX in supporting aerobic glycolysis in cancer cells with mitochondrial dysfunction and as a potential target for cancer therapyQ28483560
DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidaseQ28513159
NOX enzymes and the biology of reactive oxygenQ29547517
Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instabilityQ29618122
NADPH oxidase 1-mediated oxidative stress leads to dopamine neuron death in Parkinson's diseaseQ30512262
New insights on NOX enzymes in the central nervous systemQ33632673
Change in cell shape is required for matrix metalloproteinase-induced epithelial-mesenchymal transition of mammary epithelial cellsQ33727205
Matrix metalloproteinase-3 is increased and participates in neuronal apoptotic signaling downstream of caspase-12 during endoplasmic reticulum stressQ33883174
Targeting NOX enzymes in the central nervous system: therapeutic opportunities.Q34285497
Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agentQ34288768
Role of matrix metalloproteinase 3-mediated alpha-synuclein cleavage in dopaminergic cell deathQ34800137
Current molecular models for NADPH oxidase regulation by Rac GTPaseQ34915029
Recent developments in the pathology of Parkinson's diseaseQ35011044
Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neuronsQ35786982
Matrix compliance regulates Rac1b localization, NADPH oxidase assembly, and epithelial-mesenchymal transitionQ36312242
Microglial cells in neurodegenerative disorders.Q36370060
NADPH oxidase 1 mediates α-synucleinopathy in Parkinson's diseaseQ36408665
A generalised increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease.Q36880536
MMP-3 contributes to nigrostriatal dopaminergic neuronal loss, BBB damage, and neuroinflammation in an MPTP mouse model of Parkinson's diseaseQ36990134
NOX enzymes in the central nervous system: from signaling to diseaseQ37421768
Matrix Metalloproteinases Are Modifiers of Huntingtin Proteolysis and Toxicity in Huntington's DiseaseQ39673821
The role of NADPH oxidase 1-derived reactive oxygen species in paraquat-mediated dopaminergic cell deathQ39850050
Cross-talk between mitochondria and NADPH oxidase: effects of mild mitochondrial dysfunction on angiotensin II-mediated increase in Nox isoform expression and activity in vascular smooth muscle cellsQ39873906
A novel intracellular role of matrix metalloproteinase-3 during apoptosis of dopaminergic cellsQ39993979
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectdopamineQ170304
P304page(s)e115954
P577publication date2014-12-23
P1433published inPLOS OneQ564954
P1476titleMatrix metalloproteinase-3 causes dopaminergic neuronal death through Nox1-regenerated oxidative stress
P478volume9

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cites work (P2860)
Q36566963Associations of Matrix Metalloproteinase-9 and Tissue Inhibitory Factor-1 Polymorphisms With Parkinson Disease in Taiwan
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Q40037217Inhibiting Matrix Metalloproteinase 3 Ameliorates Neuronal Loss in the Ganglion Cell Layer of Rats in Retinal Ischemia/Reperfusion
Q38836225Intricate Functions of Matrix Metalloproteinases in Physiological and Pathological Conditions.
Q41369321Irisflorentin improves α-synuclein accumulation and attenuates 6-OHDA-induced dopaminergic neuron degeneration, implication for Parkinson's disease therapy
Q37465463MMP-3 Deficiency Alleviates Endotoxin-Induced Acute Inflammation in the Posterior Eye Segment
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Q36101048Re-Cloning the N27 Dopamine Cell Line to Improve a Cell Culture Model of Parkinson's Disease
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