Ischemia-reperfusion Injury in the Brain: Mechanisms and Potential Therapeutic Strategies.

scientific article

Ischemia-reperfusion Injury in the Brain: Mechanisms and Potential Therapeutic Strategies. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.4172/2167-0501.1000213
P932PMC publication ID5991620
P698PubMed publication ID29888120

P2093author name stringWang X
Yu Z
Lin L
P2860cites workSpatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosisQ24337576
NADPH Oxidase: A Potential Target for Treatment of StrokeQ26768464
Review, historical context, and clarifications of the NINDS rt-PA stroke trials exclusion criteria: Part 1: rapidly improving stroke symptomsQ26825583
The dynamin-related GTPase Dnm1 regulates mitochondrial fission in yeast.Q27932045
The dynamin-related GTPase, Mgm1p, is an intermembrane space protein required for maintenance of fusion competent mitochondriaQ27938333
Inhibition of myocardial injury by ischemic postconditioning during reperfusion: comparison with ischemic preconditioningQ28187266
Novel docosanoids inhibit brain ischemia-reperfusion-mediated leukocyte infiltration and pro-inflammatory gene expressionQ28199385
Molecular mechanisms of ischemia-reperfusion injury in brain: pivotal role of the mitochondrial membrane potential in reactive oxygen species generationQ28386436
Leukocyte-endothelial cell adhesion: avenues for therapeutic interventionQ29544231
NOX enzymes and the biology of reactive oxygenQ29547517
Mitochondrial fission, fusion, and stressQ29616536
Effects of allopurinol and deferoxamine on reperfusion injury of the brain in newborn piglets after neonatal hypoxia-ischemiaQ30804951
Reperfusion injury following cerebral ischemia: pathophysiology, MR imaging, and potential therapiesQ31086283
Reduced microvascular thrombosis and improved outcome in acute murine stroke by inhibiting GP IIb/IIIa receptor-mediated platelet aggregationQ32000831
Inhibition of complement as a therapeutic approach in inflammatory central nervous system (CNS) diseaseQ33769083
Inflammatory mediators of cerebral endothelium: a role in ischemic brain inflammation.Q33834652
Complement activation following oxidative stressQ33852682
Leukotriene B4 receptor transgenic mice reveal novel protective roles for lipoxins and aspirin-triggered lipoxins in reperfusionQ33853630
The role of the complement cascade in ischemia/reperfusion injury: implications for neuroprotectionQ34320047
Role of the complement system in ischaemic heart disease: potential for pharmacological interventionQ34387513
Mitochondrial fusion and fission in mammalsQ34526830
Fragmented mitochondria are sensitized to Bax insertion and activation during apoptosisQ34718003
Reperfusion damage following focal ischemia: pathophysiology and therapeutic windows.Q34740902
Apoptosis and necrosis in health and disease: Role of mitochondriaQ35117847
Matrix metalloproteinase-9 in an exploratory trial of intravenous minocycline for acute ischemic strokeQ35234799
Role of platelets in coronary thrombosis and reperfusion of ischemic myocardiumQ35666909
Sublytic concentrations of the membrane attack complex of complement induce endothelial interleukin-8 and monocyte chemoattractant protein-1 through nuclear factor-kappa B activationQ35764786
Platelet-activating factor receptor (PAFR) plays a crucial role in experimental global cerebral ischemia and reperfusion.Q53130784
PAF antagonist ginkgolide B reduces postischemic neuronal damage in rat brain hippocampusQ68699960
Leukocyte and platelet depletion protects the liver from damage induced by cholestasis and ischemia-reperfusion in the dogQ71134429
Effects of leukocyte and platelet depletion on ischemia-reperfusion injury to dog pancreasQ71650220
Anti–Intercellular Adhesion Molecule–1 Antibody Reduces Ischemic Cell Damage After Transient But Not Permanent Middle Cerebral Artery Occlusion in the Wistar RatQ71948073
Platelet-induced neutrophil activation: platelet-expressed fibrinogen induces the oxidative burst in neutrophils by an interaction with CD11C/CD18Q72046324
In vivo detection of superoxide anion production by the brain using a cytochrome c electrodeQ72556563
Temporal profile of ischemic tissue damage, neutrophil response, and vascular plugging following permanent and transient (2H) middle cerebral artery occlusion in the ratQ72816172
Value of superoxide dismutase for prevention of multiple organ failure after multiple traumaQ72832160
Intracoronary application of C1 esterase inhibitor improves cardiac function and reduces myocardial necrosis in an experimental model of ischemia and reperfusionQ73047646
Complement C1q is dramatically up-regulated in brain microglia in response to transient global cerebral ischemiaQ73755975
The LFA-1 integrin supports rolling adhesions on ICAM-1 under physiological shear flow in a permissive cellular environmentQ73910781
Circulating platelets show increased activation in patients with acute cerebral ischemiaQ74671046
Synergism between platelets and neutrophils in provoking cardiac dysfunction after ischemia and reperfusion: role of selectinsQ77343731
Early blood-brain barrier disruption in human focal brain ischemiaQ80609599
Evidence of reperfusion injury, exacerbated by thrombolytic therapy, in human focal brain ischemia using a novel imaging marker of early blood-brain barrier disruptionQ80837184
In vivo and in vitro characterization of a novel neuroprotective strategy for stroke: ischemic postconditioningQ81326092
Production of platelet-activating factor during focal cerebral ischemia and reperfusion in the ratQ81351425
Vascular ischaemia and reperfusion injuryQ35923162
Fine-tuning of Drp1/Fis1 availability by AKAP121/Siah2 regulates mitochondrial adaptation to hypoxiaQ35990125
Cytochrome C release from CNS mitochondria and potential for clinical intervention in apoptosis-mediated CNS diseasesQ36237572
The WD repeat protein, Mdv1p, functions as a molecular adaptor by interacting with Dnm1p and Fis1p during mitochondrial fissionQ36325123
Platelet—neutrophil interactions: Their significanceQ36334304
PECAM-1 is required for transendothelial migration of leukocytesQ36362038
Which came first, the cytochrome c release or the mitochondrial fission?Q36501201
(De)constructing mitochondria: what for?Q36547042
Reperfusion-induced injury to the blood-brain barrier after middle cerebral artery occlusion in ratsQ36735367
Curcuminoids limit neutrophil-mediated reperfusion injury in experimental stroke by targeting the endotheliumQ37086468
Expansion of the time window for treatment of acute ischemic stroke with intravenous tissue plasminogen activator: a science advisory from the American Heart Association/American Stroke Association.Q37436384
Protecting against ischemia-reperfusion injury: antiplatelet drugs, statins, and their potential interactionsQ37800991
Genetics of ischemic stroke, stroke-related risk factors, stroke precursors and treatmentsQ37998525
The complement system in ischemia-reperfusion injuriesQ38042217
Blood-brain barrier, reperfusion injury, and hemorrhagic transformation in acute ischemic stroke.Q38046199
Ischemia/reperfusion injury: effect of simultaneous inhibition of plasma cascade systems versus specific complement inhibition.Q38175226
The Year Embolectomy Won: a Review of Five Trials Assessing the Efficacy of Mechanical Intervention in Acute StrokeQ38587655
Inhibiting mitochondrial fission protects the heart against ischemia/reperfusion injuryQ39710554
Increased globulin and its association with hemorrhagic transformation in patients receiving intra-arterial thrombolysis therapyQ41458166
Metabolic Stress and Disorders Related to Alterations in Mitochondrial Fission or FusionQ41949133
Expression of the receptor for complement C5a (CD88) is up-regulated on reactive astrocytes, microglia, and endothelial cells in the inflamed human central nervous system.Q41976321
Post-conditioning and reperfusion injury in the treatment of strokeQ42057700
The presence of alpha-catenin in the VE-cadherin complex is required for efficient transendothelial migration of leukocytesQ42637284
Oxidative stress after thrombolysis-induced reperfusion in human stroke.Q43149020
Involvement of matrix metalloproteinase in thrombolysis-associated hemorrhagic transformation after embolic focal ischemia in ratsQ43901758
Neuroprotective effects of the SCR1-3 functional domain of CR1 on acute cerebral ischemia and reperfusion injury in ratsQ44006418
Modulation of leukocyte recruitment and IL-8 expression by the membrane attack complex of complement (C5b-9) in a rabbit model of antigen-induced arthritis.Q44290211
Nanoparticle-mediated delivery of superoxide dismutase to the brain: an effective strategy to reduce ischemia-reperfusion injuryQ44306092
The role of neutrophils and platelets in a rabbit model of thromboembolic strokeQ44470078
Impact of pexelizumab, an anti-C5 complement antibody, on total mortality and adverse cardiovascular outcomes in cardiac surgical patients undergoing cardiopulmonary bypassQ44781832
Interrupting reperfusion as a stroke therapy: ischemic postconditioning reduces infarct size after focal ischemia in ratsQ46205659
Ischemic post-conditioning protects brain and reduces inflammation in a rat model of focal cerebral ischemia/reperfusionQ46772986
NADPH oxidase plays a central role in blood-brain barrier damage in experimental strokeQ46966136
Blockade of the mitochondrial permeability transition pore diminishes infarct size in the rat after transient middle cerebral artery occlusionQ47261125
Application of in vivo ESR spectroscopy to measurement of cerebrovascular ROS generation in strokeQ47314584
Platelet-endothelial cell interactions during ischemia/reperfusion: the role of P-selectinQ47869831
Correlation between myeloperoxidase-quantified neutrophil accumulation and ischemic brain injury in the rat. Effects of neutrophil depletionQ48094083
Neuronal protection in stroke by an sLex-glycosylated complement inhibitory proteinQ48152488
Reperfusion after thrombolytic therapy in ischemic stroke measured by single-photon emission computed tomographyQ48197994
Reperfusion injury after focal cerebral ischemia: the role of inflammation and the therapeutic horizonQ48331684
Postischemic infusion of Cu/Zn superoxide dismutase or SOD:Tet451 reduces cerebral infarction following focal ischemia/reperfusion in rats.Q48648395
Remote ischemic post-conditioning reduced brain damage in experimental ischemia/reperfusion injury.Q50275842
N2 extenuates experimental ischemic stroke through platelet aggregation inhibition.Q50550243
A chemical inhibitor of DRP1 uncouples mitochondrial fission and apoptosis.Q51962923
P433issue4
P921main subjectreperfusion injuryQ1413991
P577publication date2016-06-20
P1433published inBiochemistry & pharmacology : open accessQ27724920
P1476titleIschemia-reperfusion Injury in the Brain: Mechanisms and Potential Therapeutic Strategies
P478volume5

Reverse relations

cites work (P2860)
Q89980449Basement Membrane Changes in Ischemic Stroke
Q100958664Characterization of a novel model of global forebrain ischaemia-reperfusion injury in mice and comparison with focal ischaemic and haemorrhagic stroke
Q90049912Heat-Shock Proteins in Neuroinflammation
Q90266688Identification of key transcription factors associated with cerebral ischemia‑reperfusion injury based on gene‑set enrichment analysis
Q92718179Infusion warm during selective hypothermia in acute ischemic stroke
Q89287836Protective Effects of Curcumin Against Ischemia-Reperfusion Injury in the Nervous System
Q89173731Puerarin protects rat brain against ischemia/reperfusion injury by suppressing autophagy via the AMPK-mTOR-ULK1 signaling pathway
Q90478376Targeting Oxidative Stress and Inflammation to Prevent Ischemia-Reperfusion Injury
Q59806662The Antiapoptosis Effect of Thunb. var. Extracts on Cerebral Ischemia Reperfusion Injury via PI3K/Akt Pathway

Search more.