Expression of the receptor for complement C5a (CD88) is up-regulated on reactive astrocytes, microglia, and endothelial cells in the inflamed human central nervous system.

scientific article published on January 1997

Expression of the receptor for complement C5a (CD88) is up-regulated on reactive astrocytes, microglia, and endothelial cells in the inflamed human central nervous system. is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID1858516
P698PubMed publication ID9006319

P2093author name stringO Götze
B P Morgan
P Gasque
J W Neal
S K Singhrao
P2860cites workC5a-induced expression of P-selectin in endothelial cellsQ24633672
C5A anaphylatoxin and its seven transmembrane-segment receptorQ28243792
Development of oligodendrocytes and Schwann cells studied with a monoclonal antibody against galactocerebrosideQ36292898
Anti-C5a receptor antibodies. Characterization of neutralizing antibodies specific for a peptide, C5aR-(9-29), derived from the predicted amino-terminal sequence of the human C5a receptor.Q38317924
Structure, function and cellular expression of complement anaphylatoxin receptorsQ40540064
Expression of complement in the brain: role in health and diseaseQ41203060
Differential expression of complement receptors on human basophils and mast cells. Evidence for mast cell heterogeneity and CD88/C5aR expression on skin mast cells.Q41294733
Expression of the receptors for the C5a anaphylatoxin, interleukin-8 and FMLP by human astrocytes and microgliaQ41321312
Expression of functional receptors for human C5a anaphylatoxin (CD88) on the human hepatocellular carcinoma cell line HepG2. Stimulation of acute-phase protein-specific mRNA and protein synthesis by human C5a anaphylatoxinQ41332829
Cellular expression of the C5a anaphylatoxin receptor (C5aR): demonstration of C5aR on nonmyeloid cells of the liver and lungQ41369548
Type 1 astrocytes and oligodendrocyte-type 2 astrocyte glial progenitors migrate toward distinct moleculesQ41789499
Induction of interleukin-8 synthesis from monocytes by human C5a anaphylatoxinQ41974509
C5a-mediated release of interleukin 6 by human monocytesQ44090473
Human microglial cells: Characterization in cerebral tissue and in primary culture, and study of their susceptibility to HIV-1 infectionQ44613060
C5a induction of human interleukin 1. Synergistic effect with endotoxin or interferon-gammaQ45245301
Anaphylatoxin C5a modulation of an alpha-adrenergic receptor system in the rat hypothalamusQ48477130
Pre-oligodendrocytes from adult human CNSQ48497799
Probing the human receptor for C5a anaphylatoxin with site-directed antibodies. Identification of a potential ligand binding site on the NH2-terminal domain.Q64983482
Identification and characterization of the effector region within human C5a responsible for stimulation of IL-6 synthesisQ68148419
Recombinant C5a stimulates transcription rather than translation of interleukin-1 (IL-1) and tumor necrosis factor: translational signal provided by lipopolysaccharide or IL-1 itselfQ68545203
Binding specificity and presynaptic action of anaphylatoxin C5a in rat brainQ69693131
Characterization of a receptor for C5a anaphylatoxin on human eosinophilsQ69939533
Role of complement in the aetiology of Pick's disease?Q71071908
Identification and characterization of the complement C5a anaphylatoxin receptor on human astrocytesQ71829063
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectendotheliumQ111140
astrocyteQ502961
microgliaQ1622829
P304page(s)31-41
P577publication date1997-01-01
P1433published inThe American Journal of PathologyQ4744259
P1476titleExpression of the receptor for complement C5a (CD88) is up-regulated on reactive astrocytes, microglia, and endothelial cells in the inflamed human central nervous system
P478volume150

Reverse relations

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