C5a alters blood-brain barrier integrity in a human in vitro model of systemic lupus erythematosus

scientific article published on 15 July 2015

C5a alters blood-brain barrier integrity in a human in vitro model of systemic lupus erythematosus is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/IMM.12489
P932PMC publication ID4552508
P698PubMed publication ID26059553

P50authorTrent M. WoodruffQ47504524
P2093author name stringJessy J Alexander
James N Jarvis
Richard J Quigg
Stanley A Schwartz
Molly Lopez
Supriya D Mahajan
Teresa Hennon
Neil U Parikh
Patrick Cunningham
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Increased levels of plasma anaphylatoxins in systemic lupus erythematosus predict flares of the disease and may elicit vascular injury in lupus cerebritisQ41279731
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Two different transduction pathways are activated by C3a and C5a anaphylatoxins on astrocytesQ44387171
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Assessment of disease activity and impending flare in patients with systemic lupus erythematosus. Comparison of the use of complement split products and conventional measurements of complementQ67569108
Detection of increased levels of circulating intercellular adhesion molecule 1 in some patients with rheumatoid arthritis but not in patients with systemic lupus erythematosus. Lack of correlation with levels of circulating vascular cell adhesion moQ72074312
Cerebrospinal fluid C3 and C4 indexes in immunological disorders of the central nervous systemQ73471627
Akt-dependent enhanced migratory capacity of Th17 cells from children with lupus nephritisQ85844477
The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction.Q33748190
Blood-brain barrier damages and intrathecal synthesis of anti-N-methyl-D-aspartate receptor NR2 antibodies in diffuse psychiatric/neuropsychological syndromes in systemic lupus erythematosusQ33765429
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Endothelial histamine H1 receptor signaling reduces blood-brain barrier permeability and susceptibility to autoimmune encephalomyelitis.Q34279208
Neurologic manifestations of systemic lupus erythematosus in children and adultsQ34310715
Moving towards a cure: blocking pathogenic antibodies in systemic lupus erythematosus.Q34753885
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Differential roles of ICAM-1 and VCAM-1 in leukocyte-endothelial cell interactions in skin and brain of MRL/faslpr miceQ35227677
C5a/CD88 signaling alters blood-brain barrier integrity in lupus through nuclear factor-κBQ35552398
TNF-like weak inducer of apoptosis promotes blood brain barrier disruption and increases neuronal cell death in MRL/lpr mice.Q35688684
Mitogen-activated protein kinases in apoptosis regulationQ35743118
Expression of Tight Junction and Drug Efflux Transporter Proteins in an in vitro Model of Human Blood-Brain BarrierQ35952488
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The receptor for complement component C3a mediates protection from intestinal ischemia-reperfusion injuries by inhibiting neutrophil mobilization.Q36915584
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P433issue1
P921main subjectblood–brain barrierQ221694
P304page(s)130-143
P577publication date2015-07-15
P1433published inImmunologyQ15754984
P1476titleC5a alters blood-brain barrier integrity in a human in vitro model of systemic lupus erythematosus
P478volume146

Reverse relations

cites work (P2860)
Q38406678All- Trans-Retinoic Acid Augments the Histopathological Outcome of Neuroinflammation and Neurodegeneration in Lupus-Prone MRL/lpr Mice
Q90312411Autoantibodies in Neuropsychiatric Disorders
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Q42102188Differential activation mechanisms of serum C5a in lupus nephritis and neuropsychiatric systemic lupus erythematosus
Q38991026Endothelial cells: source, barrier, and target of defensive mediators
Q59808939From Systemic Inflammation to Neuroinflammation: The Case of Neurolupus
Q90062401High Concentration of C5a-Induced Mitochondria-Dependent Apoptosis in Murine Kidney Endothelial Cells
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Q50116104Relationship between G proteins coupled receptors and tight junctions
Q39253402The blood brain barrier and neuropsychiatric lupus: new perspectives in light of advances in understanding the neuroimmune interface

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