HIV Blocks Interferon Induction in Human Dendritic Cells and Macrophages by Dysregulation of TBK1

scientific article published on 8 April 2015

HIV Blocks Interferon Induction in Human Dendritic Cells and Macrophages by Dysregulation of TBK1 is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.00889-15
P932PMC publication ID4468486
P698PubMed publication ID25855743

P50authorRachel A BottingQ89808438
Ashley MansellQ37376445
Anthony L. CunninghamQ39034658
P2093author name stringEve Diefenbach
Russell J Diefenbach
Min Kim
Najla Nasr
Andrew N Harman
Abdullateef A Alshehri
Alexandra Feetham
Ani Galoyan
Bonnie M Hiener
Dharshini Rambukwelle
P2860cites workManipulation of dendritic cell function by virusesQ21710678
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Hepatitis C virus NS2 protease inhibits host cell antiviral response by inhibiting IKKε and TBK1 functionsQ24301741
Ebola virus protein VP35 impairs the function of interferon regulatory factor-activating kinases IKKepsilon and TBK-1Q24318342
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The microvesicle component of HIV-1 inocula modulates dendritic cell infection and maturation and enhances adhesion to and activation of T lymphocytesQ28534504
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TBK-1 Promotes Autophagy-Mediated Antimicrobial Defense by Controlling Autophagosome MaturationQ29030353
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Vaginal myeloid dendritic cells transmit founder HIV-1.Q33744037
The macrophage in HIV-1 infection: from activation to deactivation?Q33810779
HIV infection of dendritic cells subverts the IFN induction pathway via IRF-1 and inhibits type 1 IFN productionQ34009029
Porcine epidemic diarrhea virus nucleocapsid protein antagonizes beta interferon production by sequestering the interaction between IRF3 and TBK1.Q34059146
Triggering TLR2, -3, -4, -5, and -8 reinforces the restrictive nature of M1- and M2-polarized macrophages to HIV.Q34059582
RIG-I-Mediated Antiviral Signaling Is Inhibited in HIV-1 Infection by a Protease-Mediated Sequestration of RIG-IQ34150344
Regulatory effect of IFN-kappa, a novel type I IFN, on cytokine production by cells of the innate immune systemQ34155484
A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cellsQ34635742
Transcriptome-based network analysis reveals a spectrum model of human macrophage activation.Q34659689
Glycerol monolaurate prevents mucosal SIV transmissionQ34957016
The leader proteinase of foot-and-mouth disease virus negatively regulates the type I interferon pathway by acting as a viral deubiquitinaseQ35076546
SARS coronavirus papain-like protease inhibits the type I interferon signaling pathway through interaction with the STING-TRAF3-TBK1 complexQ35119171
Plasmacytoid dendritic cells suppress HIV-1 replication but contribute to HIV-1 induced immunopathogenesis in humanized miceQ35215887
Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progressionQ35564886
Vpu-deficient HIV strains stimulate innate immune signaling responses in target cellsQ36172164
ORF45 of Kaposi's sarcoma-associated herpesvirus inhibits phosphorylation of interferon regulatory factor 7 by IKKε and TBK1 as an alternative substrateQ36246350
The pivotal role of TBK1 in inflammatory responses mediated by macrophagesQ36469148
HIV-1 accessory proteins VPR and Vif modulate antiviral response by targeting IRF-3 for degradationQ36559594
Initial HIV mucosal infection and dendritic cellsQ36870081
R5 HIV-1 envelope attracts dendritic cells to cross the human intestinal epithelium and sample luminal virions via engagement of the CCR5Q36870124
Comprehensive assessment of HIV target cells in the distal human gut suggests increasing HIV susceptibility toward the anusQ36930438
HIV-1-infected dendritic cells show 2 phases of gene expression changes, with lysosomal enzyme activity decreased during the second phaseQ37262510
Severe acute respiratory syndrome coronavirus M protein inhibits type I interferon production by impeding the formation of TRAF3.TANK.TBK1/IKKepsilon complex.Q37269093
Interferons: signaling, antiviral and viral evasionQ37342272
Human immunodeficiency virus type 1 mediates global disruption of innate antiviral signaling and immune defenses within infected cellsQ37365391
Relative resistance of HIV-1 founder viruses to control by interferon-alphaQ37532983
IFN-λsQ37917252
Recent insights into the complexity of Tank-binding kinase 1 signaling networks: the emerging role of cellular localization in the activation and substrate specificity of TBK1.Q38080359
Tissue dendritic cells as portals for HIV entryQ38125962
STING-dependent cytosolic DNA sensing pathwaysQ38169005
Mechanisms underlying the inhibition of interferon signaling by virusesQ38185897
Identification of lineage relationships and novel markers of blood and skin human dendritic cellsQ39238134
Vpu mediates depletion of interferon regulatory factor 3 during HIV infection by a lysosome-dependent mechanismQ39347085
Hepatitis B virus polymerase inhibits RIG-I- and Toll-like receptor 3-mediated beta interferon induction in human hepatocytes through interference with interferon regulatory factor 3 activation and dampening of the interaction between TBK1/IKKepsiloQ39717470
PLP2, a potent deubiquitinase from murine hepatitis virus, strongly inhibits cellular type I interferon productionQ39924024
Identification of the rabies virus alpha/beta interferon antagonist: phosphoprotein P interferes with phosphorylation of interferon regulatory factor 3.Q40416432
HIV-1 Vpu does not degrade interferon regulatory factor 3.Q41993352
Inhibition of two temporal phases of HIV-1 transfer from primary Langerhans cells to T cells: the role of langerinQ42203272
HIV infection of dendritic cells.Q42259828
Possible role of phosphoinositide-3-kinase in Mx1 protein translation and antiviral activity of interferon-omega-stimulated HeLa cellsQ44190409
HIV-1 infection of human macrophages directly induces viperin which inhibits viral production.Q44683563
M1 and M2a polarization of human monocyte-derived macrophages inhibits HIV-1 replication by distinct mechanisms.Q47884316
Within 1 h, HIV-1 uses viral synapses to enter efficiently the inner, but not outer, foreskin mucosa and engages Langerhans–T cell conjugatesQ59705671
Characterization of cultured microglia that can be infected by HIV-1Q73934630
HIV induces maturation of monocyte-derived dendritic cells and Langerhans cellsQ79326773
P433issue13
P407language of work or nameEnglishQ1860
P921main subjectdendritic cellQ506253
P304page(s)6575-6584
P577publication date2015-04-08
P1433published inJournal of VirologyQ1251128
P1476titleHIV Blocks Interferon Induction in Human Dendritic Cells and Macrophages by Dysregulation of TBK1
P478volume89

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