HSV-2 Cellular Programming Enables Productive HIV Infection in Dendritic Cells

scientific article published on 06 December 2019

HSV-2 Cellular Programming Enables Productive HIV Infection in Dendritic Cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3389/FIMMU.2019.02889
P932PMC publication ID6909011
P698PubMed publication ID31867020

P50authorEsaki M ShankarQ89220066
Rada EllegårdQ117771449
Elisa CrisciQ45346582
P2093author name stringMarie Larsson
Kristina Eriksson
Sofia Nyström
Kazuki Okuyama
Pradyot Bhattacharya
Mohammad Khalid
Cecilia Svanberg
Julia Hellblom
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New insights into the immune functions of complementQ91713267
Identification of HIV transmitting CD11c+ human epidermal dendritic cellsQ92948206
SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by VpxQ24605940
HSV-2-driven increase in the expression of α4β7 correlates with increased susceptibility to vaginal SHIV(SF162P3) infectionQ27322178
Mathematical Modeling Predicts that Increased HSV-2 Shedding in HIV-1 Infected Persons Is Due to Poor Immunologic Control in Ganglia and Genital MucosaQ27347896
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HIV-1 evades innate immune recognition through specific cofactor recruitmentQ27680544
DNA tumor virus oncogenes antagonize the cGAS-STING DNA-sensing pathwayQ28114605
Opsonization of HIV-1 by semen complement enhances infection of human epithelial cellsQ28198099
BRCA1 Regulates IFI16 Mediated Nuclear Innate Sensing of Herpes Viral DNA and Subsequent Induction of the Innate Inflammasome and Interferon-β ResponsesQ28264207
Opsonization of HIV with complement enhances infection of dendritic cells and viral transfer to CD4 T cells in a CR3 and DC-SIGN-dependent mannerQ28281774
HSV-2 glycoprotein gD targets the CC domain of tetherin and promotes tetherin degradation via lysosomal pathwayQ28595739
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Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2Q29547403
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The UL41 protein of herpes simplex virus mediates selective stabilization or degradation of cellular mRNAsQ33583191
Cytosolic-DNA-mediated, STING-dependent proinflammatory gene induction necessitates canonical NF-κB activation through TBK1Q33602916
The E3 ubiquitin ligase Ro52 negatively regulates IFN-beta production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3Q33670447
Inactivation of human immunodeficiency virus type 1 infectivity with preservation of conformational and functional integrity of virion surface proteins.Q33784777
Immature monocyte-derived dendritic cells are productively infected with herpes simplex virus type 1.Q33842412
Interactions between HIV-1 and the cell-autonomous innate immune system.Q33895123
HIV-1 efficient entry in inner foreskin is mediated by elevated CCL5/RANTES that recruits T cells and fuels conjugate formation with Langerhans cellsQ33954381
HSV-2 infection of dendritic cells amplifies a highly susceptible HIV-1 cell targetQ33954386
Complement opsonization of HIV-1 enhances the uptake by dendritic cells and involves the endocytic lectin and integrin receptor familiesQ33997250
HIV infection of dendritic cells subverts the IFN induction pathway via IRF-1 and inhibits type 1 IFN productionQ34009029
The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1Q34140181
Role of HSV-2 suppressive therapy for HIV preventionQ34184590
Herpes simplex virus 1 counteracts viperin via its virion host shutoff protein UL41Q34261465
Mucosal immunity in the female genital tract, HIV/AIDSQ34275424
Nuclear IFI16 induction of IRF-3 signaling during herpesviral infection and degradation of IFI16 by the viral ICP0 proteinQ34303188
Listeria monocytogenes induces IFNβ expression through an IFI16-, cGAS- and STING-dependent pathwayQ34324531
Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retrovirusesQ34362864
Direct and quantitative single-cell analysis of human immunodeficiency virus type 1 reactivation from latencyQ34362915
Complement opsonization of HIV-1 results in decreased antiviral and inflammatory responses in immature dendritic cells via CR3Q34364911
featureCounts: an efficient general purpose program for assigning sequence reads to genomic featuresQ34384848
cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infectionQ34469746
Risk of human immunodeficiency virus infection in herpes simplex virus type 2-seropositive persons: a meta-analysisQ34470594
Blocking of integrins inhibits HIV-1 infection of human cervical mucosa immune cells with free and complement-opsonized virionsQ34507239
IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMPQ34550996
Herpes simplex virus type 2 infection increases human immunodeficiency virus type 1 entry into human primary macrophagesQ34871621
HIV Blocks Interferon Induction in Human Dendritic Cells and Macrophages by Dysregulation of TBK1Q35745385
Dual recognition of herpes simplex viruses by TLR2 and TLR9 in dendritic cellsQ35768621
Inhibition of cGAS DNA Sensing by a Herpesvirus Virion ProteinQ36052710
A Nuclear localization signal in herpesvirus protein VP1-2 is essential for infection via capsid routing to the nuclear pore.Q36155008
Herpes simplex virus 2 infection increases HIV acquisition in men and women: systematic review and meta-analysis of longitudinal studies.Q36331074
Role of virion-associated glycosylphosphatidylinositol-linked proteins CD55 and CD59 in complement resistance of cell line-derived and primary isolates of HIV-1Q36365174
Blockade of attachment and fusion receptors inhibits HIV-1 infection of human cervical tissueQ36399466
The ubiquitin-proteasome pathway in viral infectionsQ36538328
Herpes simplex virus 2 (HSV-2) prevents dendritic cell maturation, induces apoptosis, and triggers release of proinflammatory cytokines: potential links to HSV-HIV synergyQ36559887
TNF-alpha and TLR agonists increase susceptibility to HIV-1 transmission by human Langerhans cells ex vivoQ36861237
Complement Opsonization Promotes Herpes Simplex Virus 2 Infection of Human Dendritic CellsQ36878921
Recognition of herpesviruses by the innate immune systemQ36939781
Complement-HIV interactions during all steps of viral pathogenesis.Q37055637
NLRP4 negatively regulates type I interferon signaling by targeting the kinase TBK1 for degradation via the ubiquitin ligase DTX4.Q37139809
Nuclear Innate Immune DNA Sensor IFI16 Is Degraded during Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus (KSHV): Role of IFI16 in Maintenance of KSHV Latency.Q37252928
Persistence of HIV-1 receptor-positive cells after HSV-2 reactivation is a potential mechanism for increased HIV-1 acquisitionQ37295563
Rapid viral expansion and short drug half-life explain the incomplete effectiveness of current herpes simplex virus 2-directed antiviral agentsQ37335794
SAMHD1 restricts herpes simplex virus 1 in macrophages by limiting DNA replication.Q37336418
IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication.Q37353206
Dynamics of HIV-1 recombination in its natural target cellsQ37356815
Viral DNA Sensors IFI16 and Cyclic GMP-AMP Synthase Possess Distinct Functions in Regulating Viral Gene Expression, Immune Defenses, and Apoptotic Responses during Herpesvirus InfectionQ37417352
Synthetic oligodeoxynucleotides containing suppressive TTAGGG motifs inhibit AIM2 inflammasome activation.Q37426823
IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes.Q37651854
Rapid host immune response and viral dynamics in herpes simplex virus-2 infectionQ37694574
Innate immunity against HIV-1 infectionQ38491184
Viral evasion of DNA-stimulated innate immune responsesQ38773128
Dengue virus NS2B protein targets cGAS for degradation and prevents mitochondrial DNA sensing during infection.Q38873923
Cutting edge: productive HIV-1 infection of dendritic cells via complement receptor type 3 (CR3, CD11b/CD18).Q38888884
Regulation and function of the cGAS-STING pathway of cytosolic DNA sensingQ38959510
cGAS-cGAMP-STING: The three musketeers of cytosolic DNA sensing and signalingQ38972881
Herpes simplex virus UL56 interacts with and regulates the Nedd4-family ubiquitin ligase Itch.Q39672120
Herpes simplex virus type 2 enhances HIV-1 susceptibility by affecting Langerhans cell functionQ39686406
Simian TRIM5alpha proteins reduce replication of herpes simplex virusQ39754032
Negative mucosal synergy between Herpes simplex type 2 and HIV in the female genital tractQ39787490
cGAS is activated by DNA in a length-dependent manner.Q40085505
Broad-Spectrum Inhibition of Respiratory Virus Infection by MicroRNA Mimics Targeting p38 MAPK SignalingQ40156244
HIV-1 blocks the signaling adaptor MAVS to evade antiviral host defense after sensing of abortive HIV-1 RNA by the host helicase DDX3.Q40395105
HSV-1 ICP27 targets the TBK1-activated STING signalsome to inhibit virus-induced type I IFN expressionQ40656217
SAMHD1 degradation enhances active suppression of dendritic cell maturation by HIV-1.Q41137160
Herpes simplex virus type 2-infected dendritic cells produce TNF-α, which enhances CCR5 expression and stimulates HIV production from adjacent infected cellsQ41357293
Evasion of innate cytosolic DNA sensing by a gammaherpesvirus facilitates establishment of latent infectionQ41539920
Cyclic dinucleotides trigger ULK1 (ATG1) phosphorylation of STING to prevent sustained innate immune signalingQ41851410
Early innate recognition of herpes simplex virus in human primary macrophages is mediated via the MDA5/MAVS-dependent and MDA5/MAVS/RNA polymerase III-independent pathwaysQ41867125
The viral ubiquitin ligase ICP0 is neither sufficient nor necessary for degradation of the cellular DNA sensor IFI16 during herpes simplex virus 1 infection.Q41894010
Herpes simplex virus 2-induced activation in vaginal cells involves Toll-like receptors 2 and 9 and DNA sensors DAI and IFI16.Q42265735
Herpes simplex virus 1 counteracts tetherin restriction via its virion host shutoff activityQ42266919
Mechanisms of IL-12 synthesis by human dendritic cells treated with the chemical sensitizer NiSO4.Q43043813
Polymorphisms in Toll-like receptor 3 confer natural resistance to human herpes simplex virus type 2 infectionQ45357871
Herpes simplex virus type I (HSV-1) replicates in mature dendritic cells but can only be transferred in a cell-cell contact-dependent manner.Q45368017
Dendritic cell vaccination protects mice against lethality caused by genital herpes simplex virus type 2 infectionQ45737523
The Human Cytomegalovirus Tegument Protein pp65 (pUL83) Dampens Type I Interferon Production by Inactivating the DNA Sensor cGAS without Affecting STING.Q47269122
Trafficking-Mediated STING Degradation Requires Sorting to Acidified Endolysosomes and Can Be Targeted to Enhance Anti-tumor Response.Q47293147
NEMO-IKKβ Are Essential for IRF3 and NF-κB Activation in the cGAS-STING Pathway.Q47758471
Suppressive oligodeoxynucleotides containing TTAGGG motifs inhibit cGAS activation in human monocytes.Q48160898
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P921main subjectHuman herpesvirus 2Q18965147
P304page(s)2889
P577publication date2019-12-06
P1433published inFrontiers in ImmunologyQ27723748
P1476titleHSV-2 Cellular Programming Enables Productive HIV Infection in Dendritic Cells
P478volume10

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