Role of virion-associated glycosylphosphatidylinositol-linked proteins CD55 and CD59 in complement resistance of cell line-derived and primary isolates of HIV-1

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Role of virion-associated glycosylphosphatidylinositol-linked proteins CD55 and CD59 in complement resistance of cell line-derived and primary isolates of HIV-1 is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1084/JEM.182.2.501
P932PMC publication ID2192116
P698PubMed publication ID7543140
P5875ResearchGate publication ID274169027

P50authorMiroslaw K GornyQ45671710
P2093author name stringI A Rooney
S Zolla-Pazner
M E Peeples
J P Atkinson
M Saifuddin
C J Parker
M Ghassemi
G T Spear
P2860cites workCleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
Functional properties of membrane cofactor protein of complementQ28610962
Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular cloneQ29547734
Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infectionQ29547852
Viral dynamics in human immunodeficiency virus type 1 infectionQ29547908
Association of host cell surface adhesion receptors and other membrane proteins with HIV and SIV.Q34061264
Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the diseaseQ34274473
Physiologic relevance of the membrane attack complex inhibitory protein CD59 in human seminal plasma: CD59 is present on extracellular organelles (prostasomes), binds cell membranes, and inhibits complement-mediated lysisQ34306071
Isolation and characterization of a membrane protein from normal human erythrocytes that inhibits reactive lysis of the erythrocytes of paroxysmal nocturnal hemoglobinuriaQ34576112
Human immunodeficiency virus (HIV) infection in CD4+ T lymphocytes genetically deficient in LFA-1: LFA-1 is required for HIV-mediated cell fusion but not for viral transmissionQ36229830
Complement mediates human immunodeficiency virus type 1 infection of a human T cell line in a CD4- and antibody-independent fashionQ36230054
Lysis of oncornaviruses by human serum. Isolation of the viral complement (C1) receptor and identification as p15EQ36339984
Release of decay-accelerating factor (DAF) from the cell membrane by phosphatidylinositol-specific phospholipase C (PIPLC). Selective modification of a complement regulatory proteinQ36351771
Phenotypic variation in the response to the human immunodeficiency virus among derivatives of the CEM T and WIL-2 B cell linesQ36355185
Lysis of RNA tumor viruses by human serum: direct antibody-independent triggering of the classical complement pathwayQ36359927
Involvement of human leukocyte antigen class I molecules in human immunodeficiency virus infection of CD4-positive cellsQ36635982
Complement activation by human monoclonal antibodies to human immunodeficiency virusQ36638803
The control of homologous lysisQ36705635
Neutralization of human immunodeficiency virus type 1 by complement occurs by viral lysisQ36795915
Amelioration of lytic abnormalities of paroxysmal nocturnal hemoglobinuria with decay-accelerating factorQ37686832
Decay-accelerating factor: biochemistry, molecular biology, and functionQ38201546
The regulators of complement activation (RCA) gene clusterQ38665434
Cell-surface anchoring of proteins via glycosyl-phosphatidylinositol structuresQ39532102
Human serum lyses RNA tumour virusesQ39953990
High level transient expression of a chloramphenicol acetyl transferase gene by DEAE-dextran mediated DNA transfection coupled with a dimethyl sulfoxide or glycerol shock treatment.Q40461112
Oligodendrocytes lack glycolipid anchored proteins which protect them against complement lysis. Restoration of resistance to lysis by incorporation of CD59.Q41093280
Host cell components affect the sensitivity of HIV type 1 to complement-mediated virolysisQ41459580
Presence of a dysfunctional form of CD59 on a CD59+ subclone of the U937 cell line.Q41478718
Evidence for the role of CR1 (CD35), in addition to CR2 (CD21), in facilitating infection of human T cells with opsonized HIV.Q41536475
Host cell membrane proteins on human immunodeficiency virus type 1 after in vitro infection of H9 cells and blood mononuclear cells. An immuno-electron microscopic studyQ41586309
Presence of class II histocompatibility DR proteins on the envelope of human immunodeficiency virus demonstrated by FACS analysisQ41615394
Complement and antibody mediate enhancement of HIV infection by increasing virus binding and provirus formationQ41693641
Complement-mediated, antibody-dependent enhancement of HIV-1 infection in vitro is characterized by increased protein and RNA syntheses and infectious virus releaseQ43585395
Cytomegalovirus in urine specimens has host beta 2 microglobulin bound to the viral envelope: a mechanism of evading the host immune response?Q43604543
Human T-cell leukaemia virus is not lysed by human serumQ45804305
Molecular basis of the enhanced susceptibility of the erythrocytes of paroxysmal nocturnal hemoglobinuria to hemolysis in acidified serumQ46773389
Characterization of rabbit complement component C8. Functional evidence for the species-selective recognition of C8 alpha by homologous restriction factor (CD59).Q48084817
The AIDS-associated retrovirus is not sensitive to lysis or inactivation by human serum.Q53851202
Inhibition of homologous complement by CD59 is mediated by a species-selective recognition conferred through binding to C8 within C5b-8 or C9 within C5b-9.Q53861689
Human protectin (CD59), an 18,000-20,000 MW complement lysis restricting factor, inhibits C5b-8 catalysed insertion of C9 into lipid bilayersQ67672469
Cellular proteins bound to immunodeficiency viruses: implications for pathogenesis and vaccinesQ67972576
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectHIVQ15787
virionQ1757347
cell lineQ21014462
P304page(s)501-509
P577publication date1995-08-01
P1433published inJournal of Experimental MedicineQ3186912
P1476titleRole of virion-associated glycosylphosphatidylinositol-linked proteins CD55 and CD59 in complement resistance of cell line-derived and primary isolates of HIV-1
P478volume182

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cites work (P2860)
Q40953980A "complement-ary" AIDS vaccine
Q34749137A high-affinity inhibitor of human CD59 enhances complement-mediated virolysis of HIV-1: implications for treatment of HIV-1/AIDS
Q39403858A novel approach to inhibit HIV-1 infection and enhance lysis of HIV by a targeted activator of complement
Q33997980A novel trifunctional IgG-like bispecific antibody to inhibit HIV-1 infection and enhance lysis of HIV by targeting activation of complement
Q34120941A role for caveolin 1 in assembly and budding of the paramyxovirus parainfluenza virus 5.
Q39548535AIDS vaccination studies using an ex vivo feline immunodeficiency virus model: detailed analysis of the humoral immune response to a protective vaccine
Q39609813Acquisition of complement resistance through incorporation of CD55/decay-accelerating factor into viral particles bearing baculovirus GP64.
Q45325397Age-Related Macular Degeneration: A Connection between Human Herpes Virus-6A-Induced CD46 Downregulation and Complement Activation?
Q56517281Analysis of complement-mediated lysis of SIV and SIV-infected cells reveals sex differences in vaccine-induced immune responses in Rhesus macaques
Q40518684Analysis of the interaction between respiratory syncytial virus and lipid-rafts in Hep2 cells during infection.
Q77845857Antibody-mediated neutralization of cytomegalovirus: modulation of efficacy induced through the IgG constant region
Q37093742Application of proteomics technology for analyzing the interactions between host cells and intracellular infectious agents.
Q41556124Association of complement receptor 2 polymorphisms with innate resistance to HIV-1 infection
Q45739553Attachment of human immunodeficiency virus-1 (HIV-1) particles bearing host-encoded B7-2 proteins leads to nuclear factor-kappa B- and nuclear factor of activated T cells-dependent activation of HIV-1 long terminal repeat transcription
Q27468625Biomedical applications of glycosylphosphatidylinositol-anchored proteins
Q41284460Bioorthogonal mimetics of palmitoyl-CoA and myristoyl-CoA and their subsequent isolation by click chemistry and characterization by mass spectrometry reveal novel acylated host-proteins modified by HIV-1 infection
Q35973601Blockage of CD59 Function Restores Activities of Neutralizing and Nonneutralizing Antibodies in Triggering Antibody-Dependent Complement-Mediated Lysis of HIV-1 Virions and Provirus-Activated Latently Infected Cells
Q36158037CD59 incorporation protects hepatitis C virus against complement-mediated destruction.
Q33794467Cellular compartments of human immunodeficiency virus type 1 replication in vivo: determination by presence of virion-associated host proteins and impact of opportunistic infection
Q33340974Cellular proteins in influenza virus particles
Q36412305Characterization and role of lentivirus-associated host proteins
Q34061960Comparative analysis of the transforming mechanisms of Epstein-Barr virus, Kaposi's sarcoma-associated herpesvirus, and Herpesvirus saimiri
Q33804431Complement Evasion Strategies of Viruses: An Overview
Q27469834Complement activation is required for induction of a protective antibody response against West Nile virus infection
Q34610122Complement and HIV-I infection/HIV-associated neurocognitive disorders
Q37456637Complement and antibodies: a dangerous liaison in HIV infection?
Q34162421Complement and viral pathogenesis
Q28766705Complement lysis activity in autologous plasma is associated with lower viral loads during the acute phase of HIV-1 infection
Q98899849Complement opsonization of HIV affects primary infection of human colorectal mucosa and subsequent activation of T cells
Q37083678Complement opsonization of HIV-1 results in a different intracellular processing pattern and enhanced MHC class I presentation by dendritic cells
Q34364911Complement opsonization of HIV-1 results in decreased antiviral and inflammatory responses in immature dendritic cells via CR3
Q73992849Complement receptors in HIV infection
Q45879541Complement regulatory proteins are incorporated into lentiviral vectors and protect particles against complement inactivation
Q37055637Complement-HIV interactions during all steps of viral pathogenesis.
Q38673539Comprehensive Cross-Clade Characterization of Antibody-Mediated Recognition, Complement-Mediated Lysis, and Cell-Mediated Cytotoxicity of HIV-1 Envelope-Specific Antibodies toward Eradication of the HIV-1 Reservoir.
Q34400002Control of the complement system.
Q40708603Critical role of complement and viral evasion of complement in acute, persistent, and latent gamma-herpesvirus infection
Q92675561Dengue virus and the complement alternative pathway
Q33834852Detection of antibody-dependent complement-mediated inactivation of both autologous and heterologous virus in primary human immunodeficiency virus type 1 infection
Q33842620Differential incorporation of CD45, CD80 (B7-1), CD86 (B7-2), and major histocompatibility complex class I and II molecules into human immunodeficiency virus type 1 virions and microvesicles: implications for viral pathogenesis and immune regulation
Q45710613Direct Binding of Herpes Simplex Virus Type 1 Virions to Complement C3
Q41810495Dissecting the regions of virion-associated Kaposi's sarcoma-associated herpesvirus complement control protein required for complement regulation and cell binding.
Q33780497Distinct mechanisms of CD4+ and CD8+ T-cell activation and bystander apoptosis induced by human immunodeficiency virus type 1 virions
Q36102200Dynamic Association between HIV-1 Gag and Membrane Domains.
Q35363127Dynamic antibody specificities and virion concentrations in circulating immune complexes in acute to chronic HIV-1 infection
Q36506821Effect of complement on HIV-2 plasma antiviral activity is intratype specific and potent
Q39245066Effector mechanisms of humoral immunity to porcine reproductive and respiratory syndrome virus
Q36366046Efficient destruction of human immunodeficiency virus in human serum by inhibiting the protective action of complement factor H and decay accelerating factor (DAF, CD55).
Q40863577Expression of MHC class II in T cells is associated with increased HIV-1 expression
Q39728306Expression of complement regulatory protein on porcine endogenous retrovirus (PERV) depends on molecular size.
Q41010789Expression of pig endogenous retrovirus by primary porcine endothelial cells and infection of human cells
Q21245045Extensive complement-dependent enhancement of HIV-1 by autologous non-neutralising antibodies at early stages of infection
Q36496450Extracellular enveloped vaccinia virus is resistant to complement because of incorporation of host complement control proteins into its envelope.
Q92005460Friend retrovirus studies reveal complex interactions between intrinsic, innate and adaptive immunity
Q41741684Functions of Antibodies.
Q35382894Gag induces the coalescence of clustered lipid rafts and tetraspanin-enriched microdomains at HIV-1 assembly sites on the plasma membrane.
Q47555792Glycosyl-phosphatidylinositol-Anchored Anti-HIV Env Single Chain Variable Fragments Interfere with HIV-1 Env Processing and Viral Infectivity
Q40657302Glycosylphosphatidylinositol Anchor Deficiency Attenuates the Production of Infectious HIV-1 and Renders Virions Sensitive to Complement Attack
Q30372278HIV immunopathogenesis and strategies for intervention.
Q37341025HIV induced AIDS and related cancers: chronic immune activation and future therapeutic strategies
Q92188956HSV-2 Cellular Programming Enables Productive HIV Infection in Dendritic Cells
Q35882308Host cell-dependent alterations in envelope components of human immunodeficiency virus type 1 virions
Q35882741Host-derived ICAM-1 glycoproteins incorporated on human immunodeficiency virus type 1 are biologically active and enhance viral infectivity.
Q34331007Human CD59 incorporation into porcine endogenous retrovirus particles: implications for the use of transgenic pigs for xenotransplantation
Q33742139Human Immunodeficiency Virus Playing Hide-and-Seek: Understanding the TFH Cell Reservoir and Proposing Strategies to Overcome the Follicle Sanctuary
Q34070440Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein
Q40368017Human herpesvirus 6 open reading frame U14 protein and cellular p53 interact with each other and are contained in the virion
Q42794466Human immunodeficiency virus type 1 virological synapse formation in T cells requires lipid raft integrity
Q29619512Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1
Q36863847Humoral immunity to HIV-1: neutralization and beyond.
Q36623129Humoral innate immune response and disease.
Q38408016Immune Protection of Retroviral Vectors Upon Molecular Painting with the Complement Regulatory Protein CD59.
Q44953053Incorporation of decay-accelerating factor into the baculovirus envelope generates complement-resistant gene transfer vectors
Q41168464Incorporation of host complement regulatory proteins into Newcastle disease virus enhances complement evasion.
Q35772032Induction of ebolavirus cross-species immunity using retrovirus-like particles bearing the Ebola virus glycoprotein lacking the mucin-like domain
Q91911120Inflammation et virus: déclenchement,contournements et détournements de la réponse inflammatoire au cours des infections virales
Q39023294Insertion of host-derived costimulatory molecules CD80 (B7.1) and CD86 (B7.2) into human immunodeficiency virus type 1 affects the virus life cycle
Q34000215Integrity of membrane lipid rafts is necessary for the ordered assembly and release of infectious Newcastle disease virus particles
Q39337768Level of ICAM-1 surface expression on virus producer cells influences both the amount of virion-bound host ICAM-1 and human immunodeficiency virus type 1 infectivity.
Q27489393Lipids and membrane microdomains in HIV-1 replication
Q57356932Membrane transplantation to correct integral membrane protein defects
Q40349546Metabolic biotinylation of lentiviral pseudotypes for scalable paramagnetic microparticle-dependent manipulation
Q33823853Minimal incidence of serum antibodies reactive with intact primary isolate virions in human immunodeficiency virus type 1-infected individuals
Q36424527Modulation of human immunodeficiency virus type 1 infectivity through incorporation of tetraspanin proteins
Q37776790Modulation of the host immune response by cowpox virus
Q24524170Plunder and stowaways: incorporation of cellular proteins by enveloped viruses
Q36540060Potent human immunodeficiency virus-neutralizing and complement lysis activities of antibodies are not obligatorily linked
Q39682314Presence of host ICAM-1 in laboratory and clinical strains of human immunodeficiency virus type 1 increases virus infectivity and CD4(+)-T-cell depletion in human lymphoid tissue, a major site of replication in vivo
Q34218827Provirus activation plus CD59 blockage triggers antibody-dependent complement-mediated lysis of latently HIV-1-infected cells
Q36424011Quantitation of HLA proteins incorporated by human immunodeficiency virus type 1 and assessment of neutralizing activity of anti-HLA antibodies
Q33589185Rationale for a vaccine using cellular-derived epitope presented by HIV isolates
Q38341233Reduced sensitivity to human serum inactivation of enveloped viruses produced by pig cells transgenic for human CD55 or deficient for the galactosyl-alpha(1-3) galactosyl epitope
Q34666503Relationships between plasma membrane microdomains and HIV-1 assembly
Q37850839Retroviral matrix and lipids, the intimate interaction
Q41413269Role of complement and Fc receptors in the pathogenesis of HIV-1 infection
Q35134722Role of complement in the control of HIV dynamics and pathogenesis
Q45424163Role of lipid rafts in virus replication
Q40049100SERPING1 mRNA overexpression in monocytes from HIV+ patients.
Q39880641Sensitization of rhabdo-, lenti-, and spumaviruses to human serum by galactosyl(alpha1-3)galactosylation
Q51794990Separation of decay-accelerating and cofactor functional activities of Kaposi's sarcoma-associated herpesvirus complement control protein using monoclonal antibodies.
Q33782387T cells expressing activated LFA-1 are more susceptible to infection with human immunodeficiency virus type 1 particles bearing host-encoded ICAM-1
Q73076599Targeting lymph nodes with liposomes bearing anti-HLA-DR Fab' fragments
Q40960044Tetraspanins displayed in retrovirus-derived virus-like particles and their immunogenicity.
Q61812881The Incorporation of Host Proteins into the External HIV-1 Envelope
Q35976953The Trojan exosome hypothesis
Q77111813The acquisition of host-encoded proteins by nascent HIV-1
Q34212487The antiviral activity of antibodies in vitro and in vivo.
Q28275986The good and evil of complement activation in HIV-1 infection
Q40121574The nucleoside triphosphate diphosphohydrolase-1/CD39 is incorporated into human immunodeficiency type 1 particles, where it remains biologically active
Q35877952The presence of host-derived HLA-DR1 on human immunodeficiency virus type 1 increases viral infectivity
Q33817487The resistance of retroviral vectors produced from human cells to serum inactivation in vivo and in vitro is primate species dependent.
Q37113972The role of Fc receptors in HIV prevention and therapy
Q34434835Vaccinia virus proteome: identification of proteins in vaccinia virus intracellular mature virion particles
Q33688595Viral complement regulatory proteins
Q35122624Viral mimicry of the complement system
Q27477691West Nile virus nonstructural protein NS1 inhibits complement activation by binding the regulatory protein factor H

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