Phenotypic variation in the response to the human immunodeficiency virus among derivatives of the CEM T and WIL-2 B cell lines

scientific article

Phenotypic variation in the response to the human immunodeficiency virus among derivatives of the CEM T and WIL-2 B cell lines is …
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scholarly articleQ13442814

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P356DOI10.1084/JEM.168.2.605
P932PMC publication ID2188999
P698PubMed publication ID3261775
P5875ResearchGate publication ID275109177

P50authorDani BolognesiQ109936341
Michael SkinnerQ38544315
Kent J. WeinholdQ109935303
P2093author name stringM S Hershfield
T J Matthews
J M Leeds
S Chaffee
P2860cites workThe CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirusQ28259668
Detection, Isolation, and Continuous Production of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and Pre-AIDSQ28262859
Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by 2',3'-dideoxynucleosidesQ28360374
Effects of mutational loss of adenosine kinase and deoxycytidine kinase on deoxyATP accumulation and deoxyadenosine toxicity in cultured CEM human T-lymphoblastoid cellsQ28622852
Binding of the human retrovirus HTLV-III/LAV/ARV/HIV to the CD4 (T4) molecule: conformation dependence, epitope mapping, antibody inhibition, and potential for idiotypic mimicryQ28646789
Binding of HTLV-III/LAV to T4+ T cells by a complex of the 110K viral protein and the T4 moleculeQ28646808
Functional regions of the envelope glycoprotein of human immunodeficiency virus type 1Q28646812
T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAVQ28646817
An inducible transcription factor activates expression of human immunodeficiency virus in T cellsQ29618434
The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brainQ29618472
Interaction between the human T-cell lymphotropic virus type IIIB envelope glycoprotein gp120 and the surface antigen CD4: role of carbohydrate in binding and cell fusionQ34335264
Infection of monocyte/macrophages by human T lymphotropic virus type III.Q34579117
Fusion as a mediator of cytolysis in mixtures of uninfected CD4+ lymphocytes and cells infected by human immunodeficiency virusQ34603040
Human immunodeficiency virus can productively infect cultured human glial cellsQ34625813
Role of envelope glycoprotein carbohydrate in human immunodeficiency virus (HIV) infectivity and virus-induced cell fusionQ36353187
Infection of brain-derived cells with the human immunodeficiency virusQ36886797
Differences among human immunodeficiency virus strains in their capacities to induce cytolysis or persistent infection of a lymphoblastoid cell line immortalized by Epstein-Barr virusQ36887752
Prospect for prevention of human immunodeficiency virus infection: purified 120-kDa envelope glycoprotein induces neutralizing antibodyQ37399845
Restricted neutralization of divergent human T-lymphotropic virus type III isolates by antibodies to the major envelope glycoproteinQ37412527
Characterization of a continuous T-cell line susceptible to the cytopathic effects of the acquired immunodeficiency syndrome (AIDS)-associated retrovirusQ37546388
Adenine and Adenosine Are Toxic to Human Lymphoblast Mutants Defective in Purine Salvage EnzymesQ40094844
Differential susceptibility to the acquired immunodeficiency syndrome retrovirus in cloned cells of human leukemic T-cell line Molt-4.Q40126058
The cellular receptor (CD4) of the human immunodeficiency virus is expressed on neurons and glial cells in human brainQ41808623
AIDS retrovirus induced cytopathology: giant cell formation and involvement of CD4 antigenQ41830365
Role of the HTLV-III/LAV envelope in syncytium formation and cytopathicityQ43894349
HTLV-III infection of EBV-genome-positive B-lymphoid cells with or without detectable T4 antigensQ44519991
Detection of HIV-1 neutralizing antibodies by a simple, rapid, colorimetric assayQ44626333
Adaptation of Lymphadenopathy Associated Virus (LAV) to Replication in EBV-Transformed B Lymphoblastoid Cell LinesQ45796470
Detection of AIDS virus in macrophages in brain tissue from AIDS patients with encephalopathyQ45836320
Human T lymphotropic virus type III infection of human alveolar macrophages.Q45836633
In vitro infection of human monocytes with human T lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV).Q45836762
Genomic diversity of human T-lymphotropic virus type III (HTLV-III).Q45838359
HTLV-III/LAV-neutralizing antibodies to an E. coli-produced fragment of the virus envelopeQ45848174
CONTINUOUS CULTURE OF HUMAN LYMPHOBLASTS FROM PERIPHERAL BLOOD OF A CHILD WITH ACUTE LEUKEMIA.Q52828546
Patterns of antigenic expression on human monocytes as defined by monoclonal antibodiesQ52833928
Human lymphoblastoid lines from lymph node and spleenQ53438096
Induction of CD4-dependent cell fusion by the HTLV-III/LAV envelope glycoprotein.Q53534022
Determinants of deoxyadenosine toxicity in hybrids between human T- and B- lymphoblasts as a model for the development of drug resistance in T-cell acute lymphoblastic leukemia.Q54452589
Cellular tropism of the human retrovirus HTLV-III/LAV. I. Role of T cell activation and expression of the T4 antigen.Q55244766
Productive HTLV-III infection of human B cell lines.Q55245112
Dual infection of the central nervous system by AIDS viruses with distinct cellular tropisms.Q55487007
Regulation of de novo purine biosynthesis in human lymphoblasts. Coordinate control of proximal (rate-determining) steps and the inosinic acid branch pointQ68213583
AIDS-associated retroviruses (ARV) can productively infect other cells besides human T helper cellsQ68948945
Epitopes of the CD4 antigen and HIV infectionQ68977389
Differences in metabolism and cytotoxicity between 9-beta-D arabinofuranosyladenine and 9-beta-D-arabinofuranosyl-2-fluoroadenine in human leukemic lymphoblastsQ72848859
A biochemical genetic study of the role of specific nucleoside kinases in deoxyadenosine phosphorylation by cultured human cellsQ72876003
P4510describes a project that usesAA-2Q54607564
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectcell lineQ21014462
P304page(s)605-621
P577publication date1988-08-01
P1433published inJournal of Experimental MedicineQ3186912
P1476titlePhenotypic variation in the response to the human immunodeficiency virus among derivatives of the CEM T and WIL-2 B cell lines
P478volume168

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cites work (P2860)
Q73781366A Phase I safety and immunogenicity trial of UBI microparticulate monovalent HIV-1 MN oral peptide immunogen with parenteral boost in HIV-1 seronegative human subjects
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Q44423892Adaptation of HIV-1 to pigtailed macaques
Q39872431An active-site mutation in the human immunodeficiency virus type 1 proteinase (PR) causes reduced PR activity and loss of PR-mediated cytotoxicity without apparent effect on virus maturation and infectivity
Q28378612Antiretroviral activities of protease inhibitors against murine leukemia virus and simian immunodeficiency virus in tissue culture
Q36366846Autoreactive cytotoxic T lymphocytes in human immunodeficiency virus type 1-infected subjects
Q40329035B cell proliferation following CD40 stimulation results in the expression and activation of Src protein tyrosine kinase
Q33799700Containment of simian immunodeficiency virus infection: cellular immune responses and protection from rechallenge following transient postinoculation antiretroviral treatment
Q33648180Cyanovirin-N binds to gp120 to interfere with CD4-dependent human immunodeficiency virus type 1 virion binding, fusion, and infectivity but does not affect the CD4 binding site on gp120 or soluble CD4-induced conformational changes in gp120.
Q36722526Design, Development, and Interpretation of HIV Neutralization Assays
Q40043205Effect of a single amino acid substitution in the V3 domain of the human immunodeficiency virus type 1: generation of revertant viruses to overcome defects in infectivity in specific cell types
Q41165707Global analysis of lymphocyte gene expression: perturbation of H-9 cells by infection with distinct isolates of human immunodeficiency virus--an exposition by multivariate analysis of a host-parasite interface.
Q36640831Human immunodeficiency viruses containing heterologous enhancer/promoters are replication competent and exhibit different lymphocyte tropisms
Q29619512Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1
Q33784777Inactivation of human immunodeficiency virus type 1 infectivity with preservation of conformational and functional integrity of virion surface proteins.
Q28333970Inhibition of HIV-1 IIIb replication in AA-2 and MT-2 cells in culture by two ligands of poly (ADP-ribose) polymerase: 6-amino-1,2-benzopyrone and 5-iodo-6-amino-1,2-benzopyrone
Q36699076Neutralization of multiple laboratory and clinical isolates of human immunodeficiency virus type 1 (HIV-1) by antisera raised against gp120 from the MN isolate of HIV-1
Q35890968Placental trophoblasts resist infection by multiple human immunodeficiency virus (HIV) type 1 variants even with cytomegalovirus coinfection but support HIV replication after provirus transfection
Q33813173Protection of Macaca nemestrina from disease following pathogenic simian immunodeficiency virus (SIV) challenge: utilization of SIV nucleocapsid mutant DNA vaccines with and without an SIV protein boost
Q36686530Quantitation of human immunodeficiency virus type 1 infection kinetics
Q36365174Role of virion-associated glycosylphosphatidylinositol-linked proteins CD55 and CD59 in complement resistance of cell line-derived and primary isolates of HIV-1

Q54607564AA-2described by sourceP1343

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