Containment of simian immunodeficiency virus infection: cellular immune responses and protection from rechallenge following transient postinoculation antiretroviral treatment

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Containment of simian immunodeficiency virus infection: cellular immune responses and protection from rechallenge following transient postinoculation antiretroviral treatment is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.74.6.2584-2593.2000
P8608Fatcat IDrelease_3lup35q44rhbxefoudqlw44euu
P932PMC publication ID111746
P698PubMed publication ID10684272

P2093author name stringL Li
B Fisher
N Bischofberger
J D Lifson
D Wodarz
M A Nowak
M Piatak
V M Hirsch
G Walsh
B M Flynn
J L Rossio
D K Schneider
R Arnaout
R F Kiser
R J Imming
T L Parks
V J Coalter
P2860cites workViral immune evasion due to persistence of activated T cells without effector functionQ24646943
Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremiaQ28254584
HIV-specific T-helper activity in seronegative health care workers exposed to contaminated bloodQ28257275
Interferon-alpha and 3'-azido-3'-deoxythymidine are highly synergistic in mice and prevent viremia after acute retrovirus exposureQ28330415
Vaccination with a live retrovirus: the nature of the protective immune responseQ28335614
Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapyQ29615992
Early short-term 9-[2-(R)-(phosphonomethoxy)propyl]adenine treatment favorably alters the subsequent disease course in simian immunodeficiency virus-infected newborn Rhesus macaques.Q33643898
Safety, pharmacokinetics, and antiretroviral activity of intravenous 9-[2-(R)-(Phosphonomethoxy)propyl]adenine, a novel anti-human immunodeficiency virus (HIV) therapy, in HIV-infected adults.Q33697044
Effectiveness of postinoculation (R)-9-(2-phosphonylmethoxypropyl) adenine treatment for prevention of persistent simian immunodeficiency virus SIVmne infection depends critically on timing of initiation and duration of treatmentQ33782843
CD40 ligand-mediated interactions are involved in the generation of memory CD8(+) cytotoxic T lymphocytes (CTL) but are not required for the maintenance of CTL memory following virus infectionQ33783902
Inactivation of human immunodeficiency virus type 1 infectivity with preservation of conformational and functional integrity of virion surface proteins.Q33784777
Requirement for multiple lymphocyte subsets in protection by a live attenuated vaccine against retroviral infectionQ77944802
Simian immunodeficiency virus disease course is predicted by the extent of virus replication during primary infection.Q33813926
Highly attenuated vaccine strains of simian immunodeficiency virus protect against vaginal challenge: inverse relationship of degree of protection with level of attenuationQ33814150
Association between virus-specific cytotoxic T-lymphocyte and helper responses in human immunodeficiency virus type 1 infectionQ33817504
Simian immunodeficiency virus infection of monkeys as a model system for the study of AIDS pathogenesis, treatment, and preventionQ34050736
Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparationsQ34423807
9-[2-(Phosphonomethoxy)propyl]adenine therapy of established simian immunodeficiency virus infection in infant rhesus macaquesQ35129347
Patterns of viral replication correlate with outcome in simian immunodeficiency virus (SIV)-infected macaques: effect of prior immunization with a trivalent SIV vaccine in modified vaccinia virus Ankara.Q35861490
Viral dynamics of primary viremia and antiretroviral therapy in simian immunodeficiency virus infectionQ35895554
Protection against immunopathological consequences of a viral infection by activated but not resting cytotoxic T cells: T cell memory without "memory T cells"?Q35959154
Phenotypic variation in the response to the human immunodeficiency virus among derivatives of the CEM T and WIL-2 B cell linesQ36355185
The extent of early viral replication is a critical determinant of the natural history of simian immunodeficiency virus infectionQ36548993
Protective cellular retroviral immunity requires both CD4+ and CD8+ immune T cellsQ36687914
Levels of human immunodeficiency virus type 1-specific cytotoxic T-lymphocyte effector and memory responses decline after suppression of viremia with highly active antiretroviral therapyQ39595379
Identification of highly attenuated mutants of simian immunodeficiency virusQ39642374
Plasma viremia in macaques infected with simian immunodeficiency virus: plasma viral load early in infection predicts survival.Q39877649
HIV type 1-specific helper T cells: a critical host defenseQ40850639
Chemical inactivation of retroviral infectivity by targeting nucleocapsid protein zinc fingers: a candidate SIV vaccine.Q40994848
On T cell memory: arguments for antigen dependenceQ41091839
Murine and simian retrovirus models: the threshold hypothesisQ41179589
Controlling HIV pathogenesis: the role of the noncytotoxic anti-HIV response of CD8+ T cellsQ41305656
Immunology and immunity studied with virusesQ41434540
Immunization with whole inactivated vaccine protects from infection by SIV grown in human but not macaque cellsQ41491967
Characterization of clones of HIV-1 infected HuT 78 cells defective in gag gene processing and of SIV clones producing large amounts of envelope glycoproteinQ41751664
The critical need for CD4 help in maintaining effective cytotoxic T lymphocyte responsesQ41870329
CD40L-deficient mice show deficits in antiviral immunity and have an impaired memory CD8+ CTL response.Q41898717
Plasma SIV RNA viral load determination by real-time quantification of product generation in reverse transcriptase-polymerase chain reactionQ44244285
CD40 ligand is pivotal to efficient control of virus replication in mice infected with lymphocytic choriomeningitis virus.Q45753109
Protective immunity induced by live attenuated simian immunodeficiency virusQ45753990
Two doses of PMPA protect newborn macaques against oral simian immunodeficiency virus infectionQ45754857
Administration of 9-[2-(phosphonomethoxy)propyl]adenine (PMPA) for prevention of perinatal simian immunodeficiency virus infection in rhesus macaquesQ45755290
Exhaustion of CTL memory and recrudescence of viremia in lymphocytic choriomeningitis virus-infected MHC class II-deficient mice and B cell-deficient miceQ45768069
Chemoprevention of retroviral infection: success is determined by virus inoculum strength and cellular immunityQ45776852
Infectivity of titered doses of simian immunodeficiency virus clone E11S inoculated intravenously into rhesus macaques (Macaca mulatta).Q45782279
New antiretrovirals and new combinations.Q45999992
Immunomodulatory properties of antiviral acyclic nucleotide analogues: cytokine stimulatory and nitric oxide costimulatory effectsQ47937482
A functional and kinetic comparison of antiviral effector and memory cytotoxic T lymphocyte populations in vivo and in vitro.Q52040554
Dynamics of cytotoxic T-lymphocyte exhaustion.Q52247788
Control of HIV despite the Discontinuation of Antiretroviral TherapyQ56851967
Effects of (R)-9-(2-phosphonylmethoxypropyl)adenine monotherapy on chronic SIV infection in macaquesQ73379022
Antiretroviral agent (R)-9-(2-phosphonomethoxypropyl)adenine stimulates cytokine and nitric oxide productionQ73635253
Early postinfection antiviral treatment reduces viral load and prevents CD4+ cell decline in HIV type 2-infected macaquesQ73851290
Management of antiretroviral therapyQ74842321
Characterization of HIV-1-specific T-helper cells in acute and chronic infectionQ77323949
Immune control of HIV-1 replicationQ77798108
P433issue6
P921main subjectSimian immunodeficiency virusQ1890246
anti-retroviral agentQ50430310
P304page(s)2584-2593
P577publication date2000-03-01
P1433published inJournal of VirologyQ1251128
P1476titleContainment of simian immunodeficiency virus infection: cellular immune responses and protection from rechallenge following transient postinoculation antiretroviral treatment
P478volume74

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cites work (P2860)
Q77719659AIDS vaccine models: challenging challenge viruses
Q35003539AIDS vaccines and preexposure prophylaxis: is synergy possible?
Q34326613ALVAC-SIV-gag-pol-env-based vaccination and macaque major histocompatibility complex class I (A*01) delay simian immunodeficiency virus SIVmac-induced immunodeficiency
Q95785042An intrinsic way of multiclassification of endogenous psychoses. A follow-through investigation/Budapest 2000/based upon Leonhard's classification
Q44282778Anti-HIV therapeutic approaches in animal models
Q39607060Antiretroviral agents restore Mycobacterium-specific T-cell immune responses and facilitate controlling a fatal tuberculosis-like disease in Macaques coinfected with simian immunodeficiency virus and Mycobacterium bovis BCG
Q36539952Antiviral therapy during primary simian immunodeficiency virus infection fails to prevent acute loss of CD4+ T cells in gut mucosa but enhances their rapid restoration through central memory T cells
Q34762295Boosting immunity by antiviral drug therapy: a simple relationship among timing, efficacy, and success
Q34180174Broadly neutralizing antibodies and viral inducers decrease rebound from HIV-1 latent reservoirs in humanized mice
Q19028101CCL3L1-CCR5 Genotype Improves the Assessment of AIDS Risk in HIV-1-Infected Individuals
Q37072697CCL3L1-CCR5 genotype influences durability of immune recovery during antiretroviral therapy of HIV-1-infected individuals
Q34142932CD8+ and CD20+ lymphocytes cooperate to control acute simian immunodeficiency virus/human immunodeficiency virus chimeric virus infections in rhesus monkeys: modulation by major histocompatibility complex genotype
Q37730097CD8+-cell-mediated suppression of virulent simian immunodeficiency virus during tenofovir treatment
Q34223069Cellular immune responses to HIV.
Q36389032Characterization of peripheral and mucosal immune responses in rhesus macaques on long-term tenofovir and emtricitabine combination antiretroviral therapy.
Q26825814Considerations in the development of nonhuman primate models of combination antiretroviral therapy for studies of AIDS virus suppression, residual virus, and curative strategies
Q73035497Containing HIV after infection
Q34465510Control of viremia and prevention of simian-human immunodeficiency virus-induced disease in rhesus macaques immunized with recombinant vaccinia viruses plus inactivated simian immunodeficiency virus and human immunodeficiency virus type 1 particles
Q82385263DNA immunization in combination with effective antiretroviral drug therapy controls viral rebound and prevents simian AIDS after treatment is discontinued
Q64377680Durable protection of rhesus macaques immunized with a replicating adenovirus-SIV multigene prime/protein boost vaccine regimen against a second SIVmac251 rectal challenge: role of SIV-specific CD8+ T cell responses
Q36473475Early Control of Highly Pathogenic Simian Immunodeficiency Virus/Human Immunodeficiency Virus Chimeric Virus Infections in Rhesus Monkeys Usually Results in Long-Lasting Asymptomatic Clinical Outcomes
Q40295877Early Initiation of Antiretroviral Therapy Can Functionally Control Productive HIV-1 Infection in Humanized-BLT Mice
Q33762877Early antibody therapy can induce long-lasting immunity to SHIV
Q59355095Early antiretroviral therapy limits SIV reservoir establishment to delay or prevent post-treatment viral rebound
Q36481186Ecological and evolutionary principles in immunology
Q34348640Effects of cytotoxic T lymphocytes (CTL) directed against a single simian immunodeficiency virus (SIV) Gag CTL epitope on the course of SIVmac239 infection
Q45413785Effects of monotherapy with (R)-9-(2-phosphonylmethoxypropyl)adenine (PMPA) on the evolution of a primary Simian immunodeficiency virus (SIV) isolate.
Q27021082Efficacy of HIV Postexposure Prophylaxis: Systematic Review and Meta-analysis of Nonhuman Primate Studies
Q37511699Enhanced SIV replication and accelerated progression to AIDS in macaques primed to mount a CD4 T cell response to the SIV envelope protein
Q35947552Estimating the infectivity of CCR5-tropic simian immunodeficiency virus SIV(mac251) in the gut.
Q36398125HIV disease: fallout from a mucosal catastrophe?
Q22252422HIV infection: first battle decides the war
Q36104156HIV therapy: managing resistance
Q35166836HIV vaccines 1983-2003.
Q45954015HIV-1 persistence following extremely early initiation of antiretroviral therapy (ART) during acute HIV-1 infection: An observational study.
Q51637873Heterogeneity in chronic myeloid leukaemia dynamics during imatinib treatment: role of immune responses.
Q34255654Human immunodeficiency virus pathogenesis and prospects for immune control in patients with established infection
Q43522584Identification of broadly recognized, T helper 1 lymphocyte epitopes in an equine lentivirus
Q34370314Immune clearance of highly pathogenic SIV infection
Q35023525Immune intervention strategies for HIV-1 infection of humans in the SIV macaque model.
Q34876070Immune reconstitution
Q43213534Immunity and protection by live attenuated HIV/SIV vaccines
Q41982002Infection of HIV-specific CD4 T helper cells and the clonal composition of the response
Q37248025Initiation of antiretroviral therapy 48 hours after infection with simian immunodeficiency virus potently suppresses acute-phase viremia and blocks the massive loss of memory CD4+ T cells but fails to prevent disease
Q40173243Kinetics of Lymphocyte Proliferation during Primary Immune Response in Macaques Infected with Pathogenic Simian Immunodeficiency Virus SIVmac251: Preliminary Report of the Effect of Early Antiviral Therapy
Q39796603Major histocompatibility complex class I alleles associated with slow simian immunodeficiency virus disease progression bind epitopes recognized by dominant acute-phase cytotoxic-T-lymphocyte responses
Q47574091Mathematical Models of HIV Latency
Q21245370Modeling the within-host dynamics of HIV infection
Q39604412Multiple effector functions mediated by human immunodeficiency virus-specific CD4(+) T-cell clones
Q34407781Nonhuman primate models for HIV cure research
Q38643834Of Mice, Macaques, and Men: Broadly Neutralizing Antibody Immunotherapy for HIV-1.
Q34071754Optimal antiviral switching to minimize resistance risk in HIV therapy
Q33299456Potential impact of antiretroviral chemoprophylaxis on HIV-1 transmission in resource-limited settings
Q73733752Prior DNA immunization enhances immune response to dominant and subdominant viral epitopes induced by a fowlpox-based SIVmac vaccine in long-term slow-progressor macaques infected with SIVmac251
Q34712708Promises and pitfalls in the reconstitution of immunity in patients who have HIV-1 infection
Q76390304Prospects for an AIDS vaccine
Q33852720Protection against simian immunodeficiency virus vaginal challenge by using Sabin poliovirus vectors
Q33813173Protection of Macaca nemestrina from disease following pathogenic simian immunodeficiency virus (SIV) challenge: utilization of SIV nucleocapsid mutant DNA vaccines with and without an SIV protein boost
Q37273289Public clonotype usage identifies protective Gag-specific CD8+ T cell responses in SIV infection
Q35851778Requirement of diverse T-helper responses elicited by HIV vaccines: induction of highly targeted humoral and CTL responses
Q34465037Reversion of the M184V mutation in simian immunodeficiency virus reverse transcriptase is selected by tenofovir, even in the presence of lamivudine.
Q33847673Role of CD8(+) lymphocytes in control of simian immunodeficiency virus infection and resistance to rechallenge after transient early antiretroviral treatment
Q21558500Safety and adherence to intermittent pre-exposure prophylaxis (PrEP) for HIV-1 in African men who have sex with men and female sex workers
Q35752812Sequential emergence and clinical implications of viral mutants with K70E and K65R mutation in reverse transcriptase during prolonged tenofovir monotherapy in rhesus macaques with chronic RT-SHIV infection
Q35917152Structured treatment interruptions in HIV infection: benefit or disappointment?
Q34207580Structured treatment interruptions to control HIV-1 and limit drug exposure
Q38491191Success and failure of the cellular immune response against HIV-1.
Q51277967Sustained and transient oscillations and chaos induced by delayed antiviral immune response in an immunosuppressive infection model.
Q44097571Systemic vaccination prevents the total destruction of mucosal CD4 T cells during acute SIV challenge
Q30386549Targeting early infection to prevent HIV-1 mucosal transmission.
Q33971030The CD4(+) T cell response to HIV-1.
Q35200862The acute HIV infection: implications for intervention, prevention and development of an effective AIDS vaccine
Q45669391The impact of early immune destruction on the kinetics of postacute viral replication in rhesus monkey infected with the simian-human immunodeficiency virus 89.6P.
Q34632089The quest for an AIDS vaccine: is the CD8+ T-cell approach feasible?
Q55546058The race between initial T-helper expansion and virus growth upon HIV infection influences polyclonality of the response and viral set-point.
Q35851774The roles of nonhuman primates in the preclinical evaluation of candidate AIDS vaccines
Q34143945Transient antiretroviral treatment during acute simian immunodeficiency virus infection facilitates long-term control of the virus
Q44589651Transient early post‐inoculation anti‐retroviral treatment facilitates controlled infection with sparing of CD4+ T cells in gut‐associated lymphoid tissues in SIVmac239‐infected rhesus macaques, but not resistance to rechallenge
Q36228649Vaccination preserves CD4 memory T cells during acute simian immunodeficiency virus challenge
Q58815987Vaccination with CTL epitopes that escape: an alternative approach to HIV vaccine development?
Q33850355Vaccination with attenuated simian immunodeficiency virus by DNA inoculation
Q33810277Vaccine protection against simian immunodeficiency virus by recombinant strains of herpes simplex virus
Q36539997Vaccine protection by live, attenuated simian immunodeficiency virus in the absence of high-titer antibody responses and high-frequency cellular immune responses measurable in the periphery
Q33724322Vaccine-elicited memory cytotoxic T lymphocytes contribute to Mamu-A*01-associated control of simian/human immunodeficiency virus 89.6P replication in rhesus monkeys
Q34651604Vaccine-induced cellular immune responses reduce plasma viral concentrations after repeated low-dose challenge with pathogenic simian immunodeficiency virus SIVmac239
Q34332708Vaccines for the prevention of HIV-1 disease
Q39605198Variability of viral load in plasma of rhesus monkeys inoculated with simian immunodeficiency virus or simian-human immunodeficiency virus: implications for using nonhuman primate AIDS models to test vaccines and therapeutics
Q45734459Variable fate of virus-specific CD4(+) T cells during primary HIV-1 infection
Q34328792Viral dynamics during structured treatment interruptions of chronic human immunodeficiency virus type 1 infection
Q42771066Virus dynamics in the presence of synaptic transmission

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