| scholarly article | Q13442814 |
| P2093 | author name string | Nicholson JK | |
| Hicks D | |||
| McDougal JS | |||
| Cort SP | |||
| Mawle A | |||
| Cross GD | |||
| Scheppler-Campbell JA | |||
| Sligh J | |||
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | T cell activation | Q14863969 |
| Human T-lymphotropic virus 1 | Q1280388 | ||
| P304 | page(s) | 3151-3162 | |
| P577 | publication date | 1985-11-01 | |
| P1433 | published in | Journal of Immunology | Q3521441 |
| P1476 | title | Cellular tropism of the human retrovirus HTLV-III/LAV. I. Role of T cell activation and expression of the T4 antigen. | |
| P478 | volume | 135 |
| Q33645518 | 95- and 25-kDa fragments of the human immunodeficiency virus envelope glycoprotein gp120 bind to the CD4 receptor |
| Q40113669 | A novel cis-acting element that controls transcription of human immunodeficiency virus type 1 DNA, depending on cell type |
| Q39880612 | A role for natural simian immunodeficiency virus and human immunodeficiency virus type 1 nef alleles in lymphocyte activation. |
| Q33564946 | A soluble recombinant polypeptide comprising the amino-terminal half of the extracellular region of the CD4 molecule contains an active binding site for human immunodeficiency virus |
| Q33768882 | A specific defect in CD3 gamma-chain gene transcription results in loss of T-cell receptor/CD3 expression late after human immunodeficiency virus infection of a CD4+ T-cell line |
| Q38680597 | AIDS-dementia-complex: pathology, pathogenesis and future directions |
| Q24568326 | Absolute dependence on kappa B responsive elements for initiation and Tat-mediated amplification of HIV transcription in blood CD4 T lymphocytes |
| Q41672069 | Accumulation of activated CD4+ lymphocytes in the lung of individuals infected with HIV accompanied by increased virus production in patients with secondary infections |
| Q40037740 | Activation of the human immunodeficiency virus type 1 long terminal repeat by transforming mutants of human p53. |
| Q41688788 | An in vitro transcription analysis of early responses of the human immunodeficiency virus type 1 long terminal repeat to different transcriptional activators |
| Q36783073 | Antigen-driven CD4+ T cell and HIV-1 dynamics: residual viral replication under highly active antiretroviral therapy |
| Q36784041 | Antiviral effects of different CD4-immunoglobulin constructs against HIV-1 and SIV: immunological characterization, pharmacokinetic data and in vivo experiments |
| Q68092848 | Autoreactive cytotoxicity in HIV-infected individuals |
| Q37429018 | Binding of soluble CD4 proteins to human immunodeficiency virus type 1 and infected cells induces release of envelope glycoprotein gp120. |
| Q33682284 | Binding region for human immunodeficiency virus (HIV) and epitopes for HIV-blocking monoclonal antibodies of the CD4 molecule defined by site-directed mutagenesis |
| Q34264875 | Biological and biochemical characterization of a factor produced spontaneously by adherent cells of human immunodeficiency virus-infected patients inhibiting interleukin-2 receptor alpha chain (Tac) expression on normal T cells |
| Q36877620 | Biological characterization of a simian immunodeficiency virus-like retrovirus (HTLV-IV): evidence for CD4-associated molecules required for infection. |
| Q24646043 | Biosynthesis and processing of human immunodeficiency virus type 1 envelope glycoproteins: effects of monensin on glycosylation and transport |
| Q41083247 | Bispecific single chain molecules (Janusins) target cytotoxic lymphocytes on HIV infected cells |
| Q36695580 | Blocking of human immunodeficiency virus infection depends on cell density and viral stock age |
| Q36828096 | CD4-independent infection of human neural cells by human immunodeficiency virus type 1. |
| Q36802755 | CD4-independent, productive infection of a neuronal cell line by human immunodeficiency virus type 1 |
| Q36827670 | Cell-to-cell transmission of human immunodeficiency virus type 1 in the presence of azidothymidine and neutralizing antibody |
| Q39633224 | Cellular immunology of HIV-infection |
| Q36832017 | Challenge of chimpanzees (Pan troglodytes) immunized with human immunodeficiency virus envelope glycoprotein gp120 |
| Q36635210 | Characterization of human immunodeficiency virus type 1 gp120 binding to liposomes containing galactosylceramide |
| Q40100336 | Characterization of human immunodeficiency virus type 2 envelope glycoproteins: dimerization of the glycoprotein precursor during processing |
| Q36831159 | Characterization of in vitro inhibition of human immunodeficiency virus by purified recombinant CD4. |
| Q52589095 | Clinical use of lentiviral vectors. |
| Q36812230 | Cloning and characterization of human immunodeficiency virus type 1 variants diminished in the ability to induce syncytium-independent cytolysis |
| Q33745081 | Coexpression of NF-kappa B/Rel and Sp1 transcription factors in human immunodeficiency virus 1-induced, dendritic cell-T-cell syncytia |
| Q37481835 | Coexpression of human immunodeficiency virus envelope proteins and tat from a single simian virus 40 late replacement vector |
| Q33897996 | Combined single-cell quantitation of host and SIV genes and proteins ex vivo reveals host-pathogen interactions in individual cells |
| Q33826650 | Common threads in persistent viral infections |
| Q40062738 | Conformational epitope on gp120 important in CD4 binding and human immunodeficiency virus type 1 neutralization identified by a human monoclonal antibody |
| Q39878686 | Construction, replication, and immunogenic properties of a simian immunodeficiency virus expressing interleukin-2. |
| Q36231815 | Crosslinking CD4 by human immunodeficiency virus gp120 primes T cells for activation-induced apoptosis |
| Q43904367 | Cystein 402 of HIV gp 120 is essential for CD4-binding and resistance of gp 120 to intracellular degradation |
| Q40115460 | Cytocidal effect of tumor necrosis factor on cells chronically infected with human immunodeficiency virus (HIV): enhancement of HIV replication. |
| Q36520103 | Delineation of an extended surface contact area on human CD4 involved in class II major histocompatibility complex binding |
| Q34581195 | Detection of three distinct patterns of T helper cell dysfunction in asymptomatic, human immunodeficiency virus-seropositive patients. Independence of CD4+ cell numbers and clinical staging |
| Q36873079 | Development of a sensitive quantitative focal assay for human immunodeficiency virus infectivity |
| Q36698580 | Differential human immunodeficiency virus expression in CD4+ cloned lymphocytes: from viral latency to replication |
| Q36919865 | Downregulation of cell surface molecules during noncytopathic infection of T cells with human immunodeficiency virus |
| Q39597678 | Dynamics of CCR5 expression by CD4(+) T cells in lymphoid tissues during simian immunodeficiency virus infection |
| Q24564622 | Early molecular replication of human immunodeficiency virus type 1 in cultured-blood-derived T helper dendritic cells |
| Q36872993 | Effects of anti-gp120 monoclonal antibodies on CD4 receptor binding by the env protein of human immunodeficiency virus type 1 |
| Q39873967 | Effects of zidovudine-selected human immunodeficiency virus type 1 reverse transcriptase amino acid substitutions on processive DNA synthesis and viral replication. |
| Q37168506 | Elevated soluble CD8 levels in sera of human immunodeficiency virus-infected populations |
| Q39868495 | Equal levels of gp120 retention and neutralization resistance of phenotypically distinct primary human immunodeficiency virus type 1 variants upon soluble CD4 treatment |
| Q35838898 | Establishment of a stable, inducible form of human immunodeficiency virus type 1 DNA in quiescent CD4 lymphocytes in vitro |
| Q33827993 | Evidence for susceptibility of intrathymic T-cell precursors and their progeny carrying T-cell antigen receptor phenotypes TCR alpha beta + and TCR gamma delta + to human immunodeficiency virus infection: a mechanism for CD4+ (T4) lymphocyte depleti |
| Q36680103 | Expression of a human immunodeficiency virus type 1 long terminal repeat/simian virus 40 early region fusion gene in transgenic mice |
| Q37532727 | Expression of the type 1 human immunodeficiency virus Nef protein in T cells prevents antigen receptor-mediated induction of interleukin 2 mRNA. |
| Q36799015 | Failure of human immunodeficiency virus entry and infection in CD4-positive human brain and skin cells |
| Q38671045 | Follicular Regulatory T Cells Are Highly Permissive to R5-Tropic HIV-1. |
| Q36547664 | Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production |
| Q40062844 | Functional similarities between human immunodeficiency virus type 1 and simian virus 40 kappa B proto-enhancers |
| Q34603040 | Fusion as a mediator of cytolysis in mixtures of uninfected CD4+ lymphocytes and cells infected by human immunodeficiency virus |
| Q34007172 | Good cell, bad cell: flow cytometry reveals T-cell subsets important in HIV disease |
| Q41677596 | HIV induces modulation of functionally important cellular antigens |
| Q26995784 | HIV restriction in quiescent CD4⁺ T cells |
| Q34316824 | HIV-1 Nef: a multifaceted modulator of T cell receptor signaling |
| Q68562002 | HIV-1 antigenemia and T-cell activation in HIV-1 infected patients |
| Q33919765 | HIV-1 replication is controlled at the level of T cell activation and proviral integration |
| Q35836582 | HTLV-III expression in infected lymph nodes and relevance to pathogenesis of lymphadenopathy |
| Q37483781 | Highly pathogenic SHIVs and SIVs target different CD4+ T cell subsets in rhesus monkeys, explaining their divergent clinical courses |
| Q35996665 | Highly purified CD25- resting T cells cannot be infected de novo with HIV-1 |
| Q39879908 | Human T cells recovered from human/Balb radiation chimeras are hypersensitive to human immunodeficiency virus type 1 infection |
| Q34636237 | Human T-cell lymphotropic virus IIIB glycoprotein (gp120) bound to CD4 determinants on normal lymphocytes and expressed by infected cells serves as target for immune attack |
| Q36805743 | Human immunodeficiency virus envelope glycoprotein/CD4-mediated fusion of nonprimate cells with human cells |
| Q33832289 | Human immunodeficiency virus glycoprotein (gp120) induction of monocyte arachidonic acid metabolites and interleukin 1. |
| Q37347544 | Human immunodeficiency virus gp120 binding C'C" ridge of CD4 domain 1 is also involved in interaction with class II major histocompatibility complex molecules |
| Q41531689 | Human immunodeficiency virus infection of cells arrested in the cell cycle |
| Q34350307 | Human immunodeficiency virus long terminal repeat responds to T-cell activation signals |
| Q36806036 | Human immunodeficiency virus pseudotypes with expanded cellular and species tropism |
| Q45847681 | Human immunodeficiency virus replication in human brain cells. Brief report |
| Q40045880 | Human immunodeficiency virus type 1 DNA synthesis, integration, and efficient viral replication in growth-arrested T cells. |
| Q40066208 | Human immunodeficiency virus type 1 Tat-mediated trans activation correlates with the phosphorylation state of a cellular TAR RNA stem-binding factor. |
| Q36640545 | Human immunodeficiency virus type 1 infection of the brain |
| Q36533268 | Human immunodeficiency virus-induced enteropathy |
| Q34350730 | Humoral immune response to the entire human immunodeficiency virus envelope glycoprotein made in insect cells |
| Q38627387 | Identification and characterization of a long non-coding RNA up-regulated during HIV-1 infection. |
| Q33649460 | Identification and characterization of an enhancer in the coding region of the genome of human immunodeficiency virus type 1. |
| Q39588498 | Identifying the target cell in primary simian immunodeficiency virus (SIV) infection: highly activated memory CD4(+) T cells are rapidly eliminated in early SIV infection in vivo |
| Q70070146 | Immunologic abnormalities related to antigenaemia during HIV-1 infection |
| Q41465537 | Immunopathology of human immunodeficiency virus infection in the gastrointestinal tract |
| Q33930106 | In vitro activation of the HIV-1 enhancer in extracts from cells treated with a phorbol ester tumor promoter. |
| Q36825840 | In vitro mutagenesis identifies a region within the envelope gene of the human immunodeficiency virus that is critical for infectivity |
| Q41733235 | Increased glucocorticoid responsiveness of CD4+ T-cell clonal lines grown in serum-free media |
| Q45795905 | Increased serum neopterin in patients with HIV-1 infection is correlated with reduced in vitro interleukin-2 production |
| Q36654734 | Infection of macrophages with lymphotropic human immunodeficiency virus type 1 can be arrested after viral DNA synthesis |
| Q58789511 | Influenza Virus Infection of Human Lymphocytes Occurs in the Immune Cell Cluster of the Developing Antiviral Response |
| Q34517381 | Inhibition of HIV Entry by Targeting the Envelope Transmembrane Subunit gp41. |
| Q36820948 | Inhibition of human immunodeficiency virus replication in acutely infected CD4+ cells by CD8+ cells involves a noncytotoxic mechanism |
| Q70937856 | Inhibitory effect of the immunosuppressant FK506 on apoptotic cell death induced by HIV-1 gp120 |
| Q28339082 | Interaction between rifabutin and human immunodeficiency virus type 1: inhibition of replication, cytopathic effect, and reverse transcriptase in vitro |
| Q34335264 | Interaction between the human T-cell lymphotropic virus type IIIB envelope glycoprotein gp120 and the surface antigen CD4: role of carbohydrate in binding and cell fusion |
| Q35845299 | Interaction of nuclear protein p140 with human immunodeficiency virus type 1 TAR RNA in mitogen-activated primary human T lymphocytes |
| Q38348287 | Interactions of cellular proteins involved in the transcriptional regulation of the human immunodeficiency virus |
| Q41062967 | Interleukin-2 and human immunodeficiency virus infection: pathogenic mechanisms and potential for immunologic enhancement |
| Q37953457 | Is TNF involved in the progression of AIDS? |
| Q25255905 | Latency: the hidden HIV-1 challenge |
| Q36355743 | Loss of CD4 membrane expression and CD4 mRNA during acute human immunodeficiency virus replication |
| Q36783162 | Macrophage-tropic strains of human immunodeficiency virus type 1 utilize the CD4 receptor |
| Q36697574 | Mapping genetic determinants for human immunodeficiency virus type 1 resistance to soluble CD4 |
| Q40346997 | Measles virus-substance P receptor interactions. Possible novel mechanism of viral fusion |
| Q35866030 | Mechanisms of human immunodeficiency virus Type 1 (HIV-1) neutralization: irreversible inactivation of infectivity by anti-HIV-1 antibody |
| Q35676330 | Medroxyprogesterone acetate increases HIV-1 infection of unstimulated peripheral blood mononuclear cells in vitro |
| Q37181442 | Microculture assay for isolation of human immunodeficiency virus type 1 and for titration of infected peripheral blood mononuclear cells |
| Q34102337 | Minocycline attenuates HIV infection and reactivation by suppressing cellular activation in human CD4+ T cells. |
| Q36780628 | Model for intracellular folding of the human immunodeficiency virus type 1 gp120 |
| Q36798296 | Modulation of T-cell activation through protein kinase C- or A-dependent signalling pathways synergistically increases human immunodeficiency virus long terminal repeat induction by cytomegalovirus immediate-early proteins |
| Q35837061 | Molecular and biological analyses of quasispecies during evolution of a virulent simian immunodeficiency virus, SIVsmmPBj14. |
| Q39686599 | Molecular characterization of preintegration latency in human immunodeficiency virus type 1 infection |
| Q34629036 | Monoclonal anti-idiotypic antibody mimics the CD4 receptor and binds human immunodeficiency virus |
| Q45833707 | Monocyte functional studies in asymptomatic, human immunodeficiency disease virus (HIV)-infected individuals |
| Q33832811 | Mononuclear phagocytes of blood and bone marrow: comparative roles as viral reservoirs in human immunodeficiency virus type 1 infections |
| Q34579619 | Most CD4+ T cells from human immunodeficiency virus-1 infected patients can undergo prolonged clonal expansion |
| Q36648889 | Mutational analysis of the leucine zipper-like motif of the human immunodeficiency virus type 1 envelope transmembrane glycoprotein |
| Q33782330 | Mutational analysis of the virus and monoclonal antibody binding sites in MHVR, the cellular receptor of the murine coronavirus mouse hepatitis virus strain A59 |
| Q33850114 | Myb protein binds to human immunodeficiency virus 1 long terminal repeat (LTR) sequences and transactivates LTR-mediated transcription |
| Q35890514 | Nanotechnology Applications to HIV Vaccines and Microbicides |
| Q33647181 | Nef enhances human immunodeficiency virus replication and responsiveness to interleukin-2 in human lymphoid tissue ex vivo. |
| Q36651371 | Nef from primary isolates of human immunodeficiency virus type 1 suppresses surface CD4 expression in human and mouse T cells. |
| Q37466339 | Novel anti-HIV therapeutics targeting chemokine receptors and actin regulatory pathways |
| Q24628269 | Octapeptides deduced from the neuropeptide receptor-like pattern of antigen T4 in brain potently inhibit human immunodeficiency virus receptor binding and T-cell infectivity |
| Q37158205 | Optimal conditions for recovery of the human immunodeficiency virus from peripheral blood mononuclear cells |
| Q39692591 | Pathogenesis of human immunodeficiency virus infection and prospects for control |
| Q36355185 | Phenotypic variation in the response to the human immunodeficiency virus among derivatives of the CEM T and WIL-2 B cell lines |
| Q35583044 | PolyI.polyC12U-mediated inhibition of loss of alloantigen responsiveness viral replication in human CD4+ T cell clones exposed to human immunodeficiency virus in vitro |
| Q37365773 | Preferential replication of HIV-1 in the CD45RO memory cell subset of primary CD4 lymphocytes in vitro |
| Q35280089 | Progression of HIV-infection: markers or determinants |
| Q37219970 | Proposed immunopathogenic factors associated with progression from human immunodeficiency virus seropositivity to clinical disease |
| Q39875495 | Proviral burden and infection kinetics of feline immunodeficiency virus in lymphocyte subsets of blood and lymph node |
| Q33863493 | Quantifying the infectivity of human immunodeficiency virus |
| Q86763197 | Quantitative immunofluorescent assay of full-length, recombinant CD4 in solution and mapping of its epitopes |
| Q37781304 | Quiescent T cells and HIV: an unresolved relationship |
| Q36811996 | Range of CD4-Bound Conformations of HIV-1 gp120, as Defined Using Conditional CD4-Induced Antibodies |
| Q36353585 | Reinfection results in accumulation of unintegrated viral DNA in cytopathic and persistent human immunodeficiency virus type 1 infection of CEM cells |
| Q40106752 | Replication of an acutely lethal simian immunodeficiency virus activates and induces proliferation of lymphocytes. |
| Q37592488 | Replication of human immunodeficiency virus type 1 in primary dendritic cell cultures |
| Q35862415 | Requirements for lymphocyte activation by unusual strains of simian immunodeficiency virus. |
| Q36685444 | Restoration of cell surface CD4 expression in human immunodeficiency virus type 1-infected cells by treatment with a Tat antagonist |
| Q40109264 | Role of N-linked glycans of envelope glycoproteins in infectivity of human immunodeficiency virus type 1. |
| Q40375929 | SUN2 Silencing Impairs CD4 T Cell Proliferation and Alters Sensitivity to HIV-1 Infection Independently of Cyclophilin A. |
| Q39881539 | Selection of an avian retrovirus mutant with extended receptor usage |
| Q36763035 | Selective killing of CD4+ cells harboring a human immunodeficiency virus-inducible suicide gene prevents viral spread in an infected cell population |
| Q33854075 | Selective replication of simian immunodeficiency virus in a subset of CD4+ lymphocytes |
| Q42457052 | Sequences within the R region of the long terminal repeat activate basal transcription from the HIV-1 promoter. |
| Q34373003 | Serological responses in chimpanzees inoculated with human immunodeficiency virus glycoprotein (gp120) subunit vaccine |
| Q36602105 | Short Communication: Preferential Killing of HIV Latently Infected CD4(+) T Cells by MALT1 Inhibitor |
| Q35182139 | Simian immunodeficiency virus infection in neonatal macaques |
| Q36867307 | Simian retrovirus D serogroup 1 has a broad cellular tropism for lymphoid and nonlymphoid cells |
| Q42849831 | Single mutations in HIV integrase confer high-level resistance to raltegravir in primary human macrophages |
| Q36806734 | Soluble forms of herpes simplex virus glycoprotein D bind to a limited number of cell surface receptors and inhibit virus entry into cells |
| Q36873321 | Soluble gp350/220 and deletion mutant glycoproteins block Epstein-Barr virus adsorption to lymphocytes. |
| Q45729142 | Structural and functional evolution of human immunodeficiency virus type 1 long terminal repeat CCAAT/enhancer binding protein sites and their use as molecular markers for central nervous system disease progression |
| Q36780046 | Synthesis and processing of human immunodeficiency virus type 1 envelope proteins encoded by a recombinant human adenovirus |
| Q62068077 | T cell activation and disease severity in HIV infection |
| Q41876745 | T lymphocytes of the normal human cornea |
| Q36783447 | T-cell activation is required for efficient replication of human herpesvirus 6. |
| Q35885321 | The Chinese herb-derived Sparstolonin B suppresses HIV-1 transcription |
| Q38003158 | The HIV-1 passage from cytoplasm to nucleus: the process involving a complex exchange between the components of HIV-1 and cellular machinery to access nucleus and successful integration. |
| Q36645938 | The RRE of human immunodeficiency virus type 1 contributes to cell-type-specific viral tropism |
| Q40040583 | The cytoplasmic domain of CD4 is sufficient for its down-regulation from the cell surface by human immunodeficiency virus type 1 Nef. |
| Q37638962 | The cytoplasmic domain of CD4 plays a critical role during the early stages of HIV infection in T-cells |
| Q35774352 | The cytoplasmic domain of the HIV-1 glycoprotein gp41 induces NF-κB activation through TGF-β-activated kinase 1. |
| Q36366278 | The efficiency of acute infection of CD4+ T cells is markedly enhanced in the setting of antigen-specific immune activation |
| Q36231657 | The human immunodeficiency virus gp120 binding site on CD4: delineation by quantitative equilibrium and kinetic binding studies of mutants in conjunction with a high-resolution CD4 atomic structure |
| Q41768724 | The importance of nef in the induction of human immunodeficiency virus type 1 replication from primary quiescent CD4 lymphocytes. |
| Q36829155 | The intragenic enhancer of human immunodeficiency virus type 1 contains functional AP-1 binding sites. |
| Q35816763 | The pathogenetic basis of viral tropism |
| Q24564579 | The site of antiviral action of 3-nitrosobenzamide on the infectivity process of human immunodeficiency virus in human lymphocytes |
| Q34306883 | The tale of the long tail: the cytoplasmic domain of HIV-1 gp41. |
| Q36156531 | The trinity of the cortical actin in the initiation of HIV-1 infection |
| Q46361950 | The use of the clinical immunology laboratory |
| Q34355015 | Theoretical implications of cellular immune reactions against helper lymphocytes infected by an immune system retrovirus. |
| Q24556556 | Trans-activation of HIV-1 LTR-directed gene expression by tat requires protein kinase C |
| Q36781131 | Transactivation of human immunodeficiency virus promoter by human herpesvirus 6. |
| Q36827386 | Transcriptional activation of bovine leukemia virus in blood cells from experimentally infected, asymptomatic sheep with latent infections |
| Q36672196 | Transposition of the yeast retroviruslike element Ty3 is dependent on the cell cycle |
| Q34295016 | Tumor necrosis factor alpha activates human immunodeficiency virus type 1 through induction of nuclear factor binding to the NF-kappa B sites in the long terminal repeat |
| Q36643604 | Two mechanisms of soluble CD4 (sCD4)-mediated inhibition of human immunodeficiency virus type 1 (HIV-1) infectivity and their relation to primary HIV-1 isolates with reduced sensitivity to sCD4. |
| Q52727826 | Upregulation of Glucose Uptake and Hexokinase Activity of Primary Human CD4+ T Cells in Response to Infection with HIV-1. |
| Q36375339 | Viral dynamics of acute HIV-1 infection |
| Q37066794 | Viricidal effect of stimulated human mononuclear phagocytes on human immunodeficiency virus type 1 |
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