95- and 25-kDa fragments of the human immunodeficiency virus envelope glycoprotein gp120 bind to the CD4 receptor

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95- and 25-kDa fragments of the human immunodeficiency virus envelope glycoprotein gp120 bind to the CD4 receptor is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode1988PNAS...85.6543N
P356DOI10.1073/PNAS.85.17.6543
P932PMC publication ID282009
P698PubMed publication ID2842778
P5875ResearchGate publication ID20313025

P50authorHans WigzellQ6240885
P2093author name stringH Jörnvall
T Bergman
T Matthews
A Nygren
P2860cites workHigh resolution two-dimensional electrophoresis of proteinsQ24608190
Complete nucleotide sequence of the AIDS virus, HTLV-IIIQ28259080
The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirusQ28259668
Detection, Isolation, and Continuous Production of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and Pre-AIDSQ28262859
Class III human liver alcohol dehydrogenase: a novel structural type equidistantly related to the class I and class II enzymesQ28297055
Binding of the human retrovirus HTLV-III/LAV/ARV/HIV to the CD4 (T4) molecule: conformation dependence, epitope mapping, antibody inhibition, and potential for idiotypic mimicryQ28646789
Delineation of a region of the human immunodeficiency virus type 1 gp120 glycoprotein critical for interaction with the CD4 receptorQ28646793
Binding of HTLV-III/LAV to T4+ T cells by a complex of the 110K viral protein and the T4 moleculeQ28646808
Functional regions of the envelope glycoprotein of human immunodeficiency virus type 1Q28646812
T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAVQ28646817
Identification and characterization of conserved and variable regions in the envelope gene of HTLV-III/LAV, the retrovirus of AIDS.Q30355613
Computer-assisted analysis of envelope protein sequences of seven human immunodeficiency virus isolates: prediction of antigenic epitopes in conserved and variable regions.Q30356755
Interaction between the human T-cell lymphotropic virus type IIIB envelope glycoprotein gp120 and the surface antigen CD4: role of carbohydrate in binding and cell fusionQ34335264
Prospect for prevention of human immunodeficiency virus infection: purified 120-kDa envelope glycoprotein induces neutralizing antibodyQ37399845
Genomic diversity of the acquired immune deficiency syndrome virus HTLV-III: different viruses exhibit greatest divergence in their envelope genesQ37541575
HTLV-III-neutralizing antibodies in patients with AIDS and AIDS-related complexQ41379235
New human T-lymphotropic retrovirus related to simian T-lymphotropic virus type III (STLV-IIIAGM).Q43450875
Neutralization of human T-lymphotropic virus type III by sera of AIDS and AIDS-risk patientsQ44255828
Neutralization of the AIDS retrovirus by antibodies to a recombinant envelope glycoproteinQ44509170
Genomic diversity of human T-lymphotropic virus type III (HTLV-III).Q45838359
HTLV-III/LAV-neutralizing antibodies to an E. coli-produced fragment of the virus envelopeQ45848174
A specific assay measuring binding of 125I-Gp 120 from HIV to T4+/CD4+ cells.Q53530878
Cellular tropism of the human retrovirus HTLV-III/LAV. I. Role of T cell activation and expression of the T4 antigen.Q55244766
Limited proteolysis and a reactive cysteine residue define accesible regions in the native conformation of the adenovirus hexon proteinQ64381898
Electroblotting of individual polypeptides from SDS/polyacrylamide gels for direct sequence analysisQ69444621
P433issue17
P407language of work or nameEnglishQ1860
P304page(s)6543-6546
P577publication date1988-09-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476title95- and 25-kDa fragments of the human immunodeficiency virus envelope glycoprotein gp120 bind to the CD4 receptor
P478volume85

Reverse relations

cites work (P2860)
Q38345667A strategy simplifying site-directed mutagenesis in the CD4-binding region of HIV gp 120.
Q24559959CD4-binding regions of human immunodeficiency virus envelope glycoprotein gp120 defined by proteolytic digestion
Q36831159Characterization of in vitro inhibition of human immunodeficiency virus by purified recombinant CD4.
Q42218331Characterization of the prototype foamy virus envelope glycoprotein receptor-binding domain
Q43904367Cystein 402 of HIV gp 120 is essential for CD4-binding and resistance of gp 120 to intracellular degradation
Q38097291Early events in foamy virus-host interaction and intracellular trafficking
Q36831306Effects of mutations in hyperconserved regions of the extracellular glycoprotein of human immunodeficiency virus type 1 on receptor binding.
Q45074935Electroblotting of polypeptides onto glass fiber filters for direct sequence analysis after sodium dodecyl sulfate-polyacrylamide gel electrophoresis
Q40056665Envelope glycoproteins of human immunodeficiency virus type 1: profound influences on immune functions
Q36795606Identification of individual human immunodeficiency virus type 1 gp120 amino acids important for CD4 receptor binding
Q24634681Pathogenesis of human immunodeficiency virus infection
Q41752595Production and characterization of a fragment containing the HIV-gp120 binding region of CD4 using a bovine papilloma virus (BPV) vector
Q36285519Proposed atomic structure of a truncated human immunodeficiency virus glycoprotein gp120 derived by molecular modeling: target CD4 recognition and docking mechanism
Q68076655Seventh International Conference on Methods in Protein Sequence Analysis. July 3-8, 1988, West Berlin, F.R.G. Short communications
Q38337537Structure and Function in Recombinant HIV-1 gp120 and Speculation about the Disulfide Bonding in the gp120 Homologs of HIV-2 and SIV
Q68031449Study of the interaction of HIV-1 and HIV-2 envelope glycoproteins with the CD4 receptor and role of N-glycans
Q58395217The Evolution of Resistance to Simian Immunodeficiency Virus (SIV): A Review
Q33579510The N-terminal region of the human immunodeficiency virus envelope glycoprotein gp120 contains potential binding sites for CD4.
Q36669879The human immunodeficiency virus type 1 (HIV-1) CD4 receptor and its central role in promotion of HIV-1 infection.
Q41516510Truncated variants of gp120 bind CD4 with high affinity and suggest a minimum CD4 binding region

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