| scholarly article | Q13442814 |
| P356 | DOI | 10.1038/NATURE17041 |
| P698 | PubMed publication ID | 26791723 |
| P2093 | author name string | Miao Wang | |
| Randal J Kaufman | |||
| P2860 | cites work | Pharmacological brake-release of mRNA translation enhances cognitive memory | Q21128794 |
| XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease | Q22252318 | ||
| Plasma cell differentiation requires the transcription factor XBP-1 | Q24291453 | ||
| A crucial role for RACK1 in the regulation of glucose-stimulated IRE1alpha activation in pancreatic beta cells | Q24297587 | ||
| Loss of kinase activity in a patient with Wolcott-Rallison syndrome caused by a novel mutation in the EIF2AK3 gene | Q24300493 | ||
| Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response | Q24304232 | ||
| Mutations in the ER-Golgi intermediate compartment protein ERGIC-53 cause combined deficiency of coagulation factors V and VIII | Q24336195 | ||
| Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2 | Q39315996 | ||
| XBP1 Controls Maturation of Gastric Zymogenic Cells by Induction of MIST1 and Expansion of the Rough Endoplasmic Reticulum | Q39659690 | ||
| Therapeutic potential of peroxisome proliferators--activated receptor-alpha/gamma dual agonist with alleviation of endoplasmic reticulum stress for the treatment of diabetes | Q40038212 | ||
| High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress mediated beta-cell apoptosis, a characteristic of humans with type 2 but not type 1 diabetes | Q40137823 | ||
| Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease | Q40795664 | ||
| Ire1 has distinct catalytic mechanisms for XBP1/HAC1 splicing and RIDD. | Q41585784 | ||
| The CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis | Q41791624 | ||
| The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis | Q41904044 | ||
| The transcription factor cyclic AMP-responsive element-binding protein H regulates triglyceride metabolism | Q41909224 | ||
| ER stress does not cause upregulation and activation of caspase-2 to initiate apoptosis. | Q41948428 | ||
| UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators. | Q42041480 | ||
| A surveillance pathway monitors the fitness of the endoplasmic reticulum to control its inheritance | Q42176881 | ||
| ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC development | Q42199386 | ||
| Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis | Q42207479 | ||
| ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress | Q42518206 | ||
| Stress responses. Mutations in a translation initiation factor identify the target of a memory-enhancing compound | Q42552086 | ||
| Noncanonical binding of BiP ATPase domain to Ire1 and Perk is dissociated by unfolded protein CH1 to initiate ER stress signaling | Q42721735 | ||
| Activating transcription factor 4 regulates adipocyte differentiation via altering the coordinate expression of CCATT/enhancer binding protein β and peroxisome proliferator-activated receptor γ. | Q42804891 | ||
| Axonally synthesized ATF4 transmits a neurodegenerative signal across brain regions. | Q42852011 | ||
| AAV-mediated delivery of the transcription factor XBP1s into the striatum reduces mutant Huntingtin aggregation in a mouse model of Huntington's disease | Q45306832 | ||
| Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsiveness | Q45736205 | ||
| Endoplasmic reticulum stress plays a central role in development of leptin resistance | Q46178586 | ||
| Phosphorylation of eIF2α is dispensable for differentiation but required at a posttranscriptional level for paneth cell function and intestinal homeostasis in mice | Q46196513 | ||
| Atf6α-null mice are glucose intolerant due to pancreatic β-cell failure on a high-fat diet but partially resistant to diet-induced insulin resistance. | Q53181684 | ||
| Expression of endoplasmic reticulum stress markers in the islets of patients with type 1 diabetes | Q57920468 | ||
| Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress | Q61512382 | ||
| GLP-1 receptor activation improves beta cell function and survival following induction of endoplasmic reticulum stress | Q79329446 | ||
| Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1 | Q80979487 | ||
| Sustained translational repression by eIF2α-P mediates prion neurodegeneration | Q24602153 | ||
| Atf4 regulates obesity, glucose homeostasis, and energy expenditure | Q24648259 | ||
| Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival | Q24653078 | ||
| XBP-1 regulates signal transduction, transcription factors and bone marrow colonization in B cells | Q24658399 | ||
| Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsia | Q28115716 | ||
| EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndrome | Q28142981 | ||
| Translational control is required for the unfolded protein response and in vivo glucose homeostasis | Q28204066 | ||
| Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases | Q28239642 | ||
| S-nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration | Q28242222 | ||
| A molecular chaperone inducer protects neurons from ER stress | Q28259344 | ||
| Protein accumulation and neurodegeneration in the woozy mutant mouse is caused by disruption of SIL1, a cochaperone of BiP | Q28268556 | ||
| Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase | Q28280649 | ||
| Oral treatment targeting the unfolded protein response prevents neurodegeneration and clinical disease in prion-infected mice | Q28300013 | ||
| PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation | Q28507769 | ||
| Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
| CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum | Q28509611 | ||
| CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum | Q28512249 | ||
| The transcription factor XBP-1 is essential for the development and survival of dendritic cells | Q28512302 | ||
| Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes | Q28575190 | ||
| Insulin biosynthetic interaction network component, TMEM24, facilitates insulin reserve pool release | Q28584801 | ||
| Toll-like receptor-mediated IRE1α activation as a therapeutic target for inflammatory arthritis | Q28589300 | ||
| XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks | Q28591575 | ||
| Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival | Q28593963 | ||
| Phenotypic assays identify azoramide as a small-molecule modulator of the unfolded protein response with antidiabetic activity | Q28822090 | ||
| The mammalian unfolded protein response | Q29547400 | ||
| The unfolded protein response: controlling cell fate decisions under ER stress and beyond | Q29615499 | ||
| IRE1 signaling affects cell fate during the unfolded protein response | Q29615502 | ||
| C/EBP-Homologous Protein (CHOP) in Vascular Smooth Muscle Cells Regulates Their Proliferation in Aortic Explants and Atherosclerotic Lesions | Q30359005 | ||
| Xbp1s in Pomc neurons connects ER stress with energy balance and glucose homeostasis. | Q30370983 | ||
| Islet β-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nonobese diabetic mouse model | Q30421540 | ||
| Paneth cells as a site of origin for intestinal inflammation. | Q30559414 | ||
| Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins | Q33262919 | ||
| Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neurons | Q33616462 | ||
| The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis. | Q33777806 | ||
| Membrane lipid saturation activates endoplasmic reticulum unfolded protein response transducers through their transmembrane domains | Q36712468 | ||
| Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes | Q36861224 | ||
| ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death. | Q36954378 | ||
| Antioxidants reduce endoplasmic reticulum stress and improve protein secretion | Q36985084 | ||
| IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2. | Q37091581 | ||
| Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2alpha) dephosphorylation in mammalian development | Q37100863 | ||
| The unfolded protein response and chemical chaperones reduce protein misfolding and colitis in mice | Q37115015 | ||
| From endoplasmic-reticulum stress to the inflammatory response | Q37225354 | ||
| Insulin secretion and Ca2+ dynamics in β-cells are regulated by PERK (EIF2AK3) in concert with calcineurin. | Q37333746 | ||
| Translation attenuation through eIF2alpha phosphorylation prevents oxidative stress and maintains the differentiated state in beta cells | Q37343526 | ||
| Xbp1-independent Ire1 signaling is required for photoreceptor differentiation and rhabdomere morphogenesis in Drosophila | Q37381743 | ||
| Endoplasmic reticulum stress regulator XBP-1 contributes to effector CD8+ T cell differentiation during acute infection. | Q37418550 | ||
| An essential requirement for the SCAP/SREBP signaling axis to protect cancer cells from lipotoxicity | Q37573880 | ||
| Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases | Q38195215 | ||
| The impact of the endoplasmic reticulum protein-folding environment on cancer development | Q38241996 | ||
| METABOLISM. S-Nitrosylation links obesity-associated inflammation to endoplasmic reticulum dysfunction. | Q38297313 | ||
| Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. | Q38311676 | ||
| Evidence for eIF2α phosphorylation-independent effects of GSK2656157, a novel catalytic inhibitor of PERK with clinical implications | Q38663736 | ||
| XBP-1 is a cell-nonautonomous regulator of stress resistance and longevity | Q38681055 | ||
| Unfolded proteins are Ire1-activating ligands that directly induce the unfolded protein response | Q38845249 | ||
| Partial restoration of protein synthesis rates by the small molecule ISRIB prevents neurodegeneration without pancreatic toxicity | Q38903340 | ||
| Epithelial-to-mesenchymal transition activates PERK-eIF2α and sensitizes cells to endoplasmic reticulum stress | Q39007267 | ||
| IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress. | Q39299575 | ||
| Tauroursodeoxycholic Acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women. | Q34024266 | ||
| Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity | Q34181503 | ||
| Restoration of the unfolded protein response in pancreatic β cells protects mice against type 1 diabetes | Q34213205 | ||
| XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation | Q34345459 | ||
| Chemical chaperones increase the cellular activity of N370S beta -glucosidase: a therapeutic strategy for Gaucher disease | Q34386725 | ||
| Preventing proteostasis diseases by selective inhibition of a phosphatase regulatory subunit | Q34471020 | ||
| Allosteric inhibition of the IRE1α RNase preserves cell viability and function during endoplasmic reticulum stress. | Q34572339 | ||
| Sodium phenylbutyrate, a drug with known capacity to reduce endoplasmic reticulum stress, partially alleviates lipid-induced insulin resistance and beta-cell dysfunction in humans | Q34615491 | ||
| Discovery of Sulfonamidebenzamides as Selective Apoptotic CHOP Pathway Activators of the Unfolded Protein Response | Q34701285 | ||
| Transmission of endoplasmic reticulum stress and pro-inflammation from tumor cells to myeloid cells | Q34836604 | ||
| Calcium trafficking integrates endoplasmic reticulum function with mitochondrial bioenergetics | Q34841551 | ||
| Dual and opposing roles of the unfolded protein response regulated by IRE1alpha and XBP1 in proinsulin processing and insulin secretion | Q35008217 | ||
| The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response | Q35029280 | ||
| TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages. | Q35041384 | ||
| Translational control of mGluR-dependent long-term depression and object-place learning by eIF2α. | Q35121843 | ||
| MicroRNA-214 suppresses gluconeogenesis by targeting activating transcriptional factor 4 | Q35221535 | ||
| PKA phosphorylation couples hepatic inositol-requiring enzyme 1alpha to glucagon signaling in glucose metabolism | Q35229188 | ||
| Influence of the hepatic eukaryotic initiation factor 2alpha (eIF2alpha) endoplasmic reticulum (ER) stress response pathway on insulin-mediated ER stress and hepatic and peripheral glucose metabolism | Q35378742 | ||
| α-Synuclein-mediated inhibition of ATF6 processing into COPII vesicles disrupts UPR signaling in Parkinson's disease | Q35569310 | ||
| Cleavage of BLOC1S1 mRNA by IRE1 Is Sequence Specific, Temporally Separate from XBP1 Splicing, and Dispensable for Cell Viability under Acute Endoplasmic Reticulum Stress | Q35626096 | ||
| ER stress activates the NLRP3 inflammasome via an UPR-independent pathway | Q35723848 | ||
| Pharmacological ER stress promotes hepatic lipogenesis and lipid droplet formation | Q35747483 | ||
| IRE1α activation protects mice against acetaminophen-induced hepatotoxicity | Q35760821 | ||
| The IRE1α/XBP1s Pathway Is Essential for the Glucose Response and Protection of β Cells. | Q35808715 | ||
| Transdifferentiation mediated tumor suppression by the endoplasmic reticulum stress sensor IRE-1 in C. elegans | Q35866891 | ||
| Antioxidants Complement the Requirement for Protein Chaperone Function to Maintain β-Cell Function and Glucose Homeostasis. | Q35881709 | ||
| Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy | Q35909430 | ||
| PERK utilizes intrinsic lipid kinase activity to generate phosphatidic acid, mediate Akt activation, and promote adipocyte differentiation | Q36023300 | ||
| Endoplasmic Reticulum Stress Activates the Inflammasome via NLRP3- and Caspase-2-Driven Mitochondrial Damage | Q36092385 | ||
| Silencing of lipid metabolism genes through IRE1α-mediated mRNA decay lowers plasma lipids in mice. | Q36330343 | ||
| PERK is required in the adult pancreas and is essential for maintenance of glucose homeostasis | Q36435206 | ||
| IRE1α-XBP1s induces PDI expression to increase MTP activity for hepatic VLDL assembly and lipid homeostasis | Q36600595 | ||
| ER stress signalling through eIF2α and CHOP, but not IRE1α, attenuates adipogenesis in mice | Q36709748 | ||
| P433 | issue | 7586 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | endoplasmic reticulum | Q79927 |
| P304 | page(s) | 326-335 | |
| P577 | publication date | 2016-01-01 | |
| P1433 | published in | Nature | Q180445 |
| P1476 | title | Protein misfolding in the endoplasmic reticulum as a conduit to human disease | |
| P478 | volume | 529 |
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| Q37668577 | Exosomes derived from human platelet-rich plasma prevent apoptosis induced by glucocorticoid-associated endoplasmic reticulum stress in rat osteonecrosis of the femoral head via the Akt/Bad/Bcl-2 signal pathway |
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| Q40127266 | Fine-Tuning ER Stress Signal Transducers to Treat Amyotrophic Lateral Sclerosis |
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| Q88796738 | Increased mitochondrial respiration promotes survival from endoplasmic reticulum stress |
| Q60395357 | Increased sensitivity to apoptosis upon endoplasmic reticulum stress-induced activation of the unfolded protein response in chemotherapy-resistant malignant pleural mesothelioma |
| Q94512577 | Induction of blood-circulating bile acids supports recovery from myelosuppressive chemotherapy |
| Q64290049 | Inhibition of eIF2α dephosphorylation accelerates pterostilbene-induced cell death in human hepatocellular carcinoma cells in an ER stress and autophagy-dependent manner |
| Q48183802 | Inorganic arsenic causes fatty liver and interacts with ethanol to cause alcoholic liver disease in zebrafish |
| Q55262733 | Integrated Stress Responses to Bacterial Pathogenesis Patterns. |
| Q98160354 | Interaction of HSPA5 (Grp78, BIP) with negatively charged phospholipid membranes via oligomerization involving the N-terminal end domain |
| Q57784666 | Interaction of volatile organic compounds and underlying liver disease: a new paradigm for risk |
| Q48380334 | Ire1α in Pomc Neurons Is Required for Thermogenesis and Glycemia |
| Q100391104 | Irisin attenuates myocardial ischemia/reperfusion-induced cardiac dysfunction by regulating ER-mitochondria interaction through a mitochondrial ubiquitin ligase-dependent mechanism |
| Q91605042 | KSHV activates unfolded protein response sensors but suppresses downstream transcriptional responses to support lytic replication |
| Q47927511 | Knockdown of IRE1α inhibits colonic tumorigenesis through decreasing β-catenin and IRE1α targeting suppresses colon cancer cells |
| Q42314655 | LOXL2 drives epithelial-mesenchymal transition via activation of IRE1-XBP1 signalling pathway |
| Q39786328 | Lens ER-stress response during cataract development in Mip-mutant mice |
| Q37583253 | Lipid disequilibrium disrupts ER proteostasis by impairing ERAD substrate glycan trimming and dislocation |
| Q39452331 | Lipid droplet functions beyond energy storage |
| Q47107585 | Liraglutide restores chronic ER stress, autophagy impairments and apoptotic signalling in SH-SY5Y cells |
| Q93216150 | LncRNA GOLGA2P10 is induced by PERK/ATF4/CHOP signaling and protects tumor cells from ER stress-induced apoptosis by regulating Bcl-2 family members |
| Q89820818 | LncRNA LUCRC Regulates Colorectal Cancer Cell Growth and Tumorigenesis by Targeting Endoplasmic Reticulum Stress Response |
| Q90095786 | MTORC1 coordinates the autophagy and apoptosis signaling in articular chondrocytes in osteoarthritic temporomandibular joint |
| Q39104738 | Mechanisms of cell death induction by food-borne mycotoxins |
| Q91904637 | Metabolic perturbations and cellular stress underpin susceptibility to symptomatic live-attenuated yellow fever infection |
| Q92645102 | MicroRNA-10a inhibits A30P α-synuclein aggregation and toxicity by targeting proapoptotic protein BCL2L11 |
| Q47140950 | Mild endoplasmic reticulum stress ameliorates lipopolysaccharide-induced neuroinflammation and cognitive impairment via regulation of microglial polarization |
| Q48152192 | Misfolded proinsulin in the endoplasmic reticulum during development of beta cell failure in diabetes. |
| Q39204176 | Mitochondria-Associated Membranes and ER Stress. |
| Q90041357 | Mitochondrial Peptide Humanin Protects Silver Nanoparticles-Induced Neurotoxicity in Human Neuroblastoma Cancer Cells (SH-SY5Y) |
| Q98566245 | Mitochondrial glycerol 3-phosphate dehydrogenase deficiency aggravates hepatic triglyceride accumulation and steatosis |
| Q38818474 | Modulation of Molecular Chaperones in Huntington's Disease and Other Polyglutamine Disorders. |
| Q52715894 | Monoallelic Mutations to DNAJB11 Cause Atypical Autosomal-Dominant Polycystic Kidney Disease. |
| Q36355151 | Mutant uromodulin expression leads to altered homeostasis of the endoplasmic reticulum and activates the unfolded protein response. |
| Q48158915 | N-acetylcysteine alleviates cadmium-induced placental endoplasmic reticulum stress and fetal growth restriction in mice |
| Q38999100 | NF-Y (CBF) regulation in specific cell types and mouse models |
| Q89748947 | Natural products as modulators of eukaryotic protein secretion |
| Q55109555 | Neuroprotection Targeting Protein Misfolding on Chronic Cerebral Hypoperfusion in the Context of Metabolic Syndrome. |
| Q41335521 | Neuroprotection by eIF2α-CHOP inhibition and XBP-1 activation in EAE/optic neuritiss. |
| Q60949491 | New Insights into the Role of Endoplasmic Reticulum Stress in Breast Cancer Metastasis |
| Q90284695 | New perspectives on the treatment of skeletal dysplasia |
| Q92173184 | Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics |
| Q93183043 | Nε-lysine acetylation in the endoplasmic reticulum - a novel cellular mechanism that regulates proteostasis and autophagy |
| Q64115221 | Omentin protects H9c2 cells against docetaxel cardiotoxicity |
| Q42650888 | Oxidative stress and endoplasmic reticulum (ER) stress in the development of neonatal hypoxic-ischaemic brain injury |
| Q47687461 | Oxidative stress promotes SIRT1 recruitment to the GADD34/PP1α complex to activate its deacetylase function |
| Q89431878 | PARK7 modulates autophagic proteolysis through binding to the N-terminally arginylated form of the molecular chaperone HSPA5 |
| Q64923775 | PDIA1/P4HB is required for efficient proinsulin maturation and ß cell health in response to diet induced obesity. |
| Q47154682 | PERK interacts with FLNA to regulate ER-PM contact sites |
| Q38747073 | Peroxisome Proliferator-activated Receptor-γ Activation Augments the β-Cell Unfolded Protein Response and Rescues Early Glycemic Deterioration and β Cell Death in Non-obese Diabetic Mice |
| Q92003537 | Pharmacological targeting of the unfolded protein response for disease intervention |
| Q90154496 | Phosphorylation switches protein disulfide isomerase activity to maintain proteostasis and attenuate ER stress |
| Q41583320 | Physiological/pathological ramifications of transcription factors in the unfolded protein response |
| Q33884423 | Plasminogen Tochigi mice exhibit phenotypes similar to wild-type mice under experimental thrombotic conditions |
| Q37619869 | Prostate cancer and the unfolded protein response. |
| Q50133915 | Protective Effects of Olive Leaf Extract on Acrolein-Exacerbated Myocardial Infarction via an Endoplasmic Reticulum Stress Pathway |
| Q90697527 | Protective Properties of FOXO1 Inhibition in a Murine Model of Non-alcoholic Fatty Liver Disease Are Associated With Attenuation of ER Stress and Necroptosis |
| Q47378958 | Protein Folding and the Challenges of Maintaining Endoplasmic Reticulum Proteostasis in Idiopathic Pulmonary Fibrosis |
| Q57036995 | Protein Quality Control in the Endoplasmic Reticulum and Cancer |
| Q50321414 | Protein biosynthesis, a target of sorafenib, interferes with the unfolded protein response (UPR) and ferroptosis in hepatocellular carcinoma cells |
| Q52715274 | Proteomic Study Defines How Alcohol Alters ER Structure and Redox Proteome to Trigger ER Stress and Acinar Cell Pathology in Pancreatitis. |
| Q64074970 | Proteomics Study of Peripheral Blood Mononuclear Cells (PBMCs) in Autistic Children |
| Q47223871 | Proteomics reveals changes in hepatic proteins during chicken embryonic development: an alternative model to study human obesity |
| Q91712566 | RIPK1 regulates the survival of human melanocytes upon endoplasmic reticulum stress |
| Q33591883 | RNA binding motif protein 3: a potential biomarker in cancer and therapeutic target in neuroprotection |
| Q89997622 | RNAi expression tuning, microfluidic screening, and genome recombineering for improved protein production in Saccharomyces cerevisiae |
| Q47256903 | Real-Time and Non-invasive Monitoring of the Activation of the IRE1α-XBP1 Pathway in Individuals with Hemodynamic Impairment |
| Q93022937 | Recent Insights Into the Pathogenic Mechanism of Pancreatitis: Role of Acinar Cell Organelle Disorders |
| Q47283726 | Reduced Endoplasmic Reticulum Stress-Mediated Autophagy Is Required for Leptin Alleviating Inflammation in Adipose Tissue |
| Q89473746 | Retrograde signaling mediates an adaptive survival response to endoplasmic reticulum stress in Saccharomyces cerevisiae |
| Q33682452 | Role of activating transcription factor 4 in the hepatic response to amino acid depletion by asparaginase |
| Q93038145 | Role of amino acid metabolism in angiogenesis |
| Q91892215 | SPHK1 deficiency protects mice from acetaminophen-induced ER stress and mitochondrial permeability transition |
| Q52597675 | Selective Histone Deacetylase 6 Inhibitor 23BB Alleviated Rhabdomyolysis-Induced Acute Kidney Injury by Regulating Endoplasmic Reticulum Stress and Apoptosis. |
| Q51074582 | Selective Manipulation of Discrete Mannosidase Activities in the Endoplasmic Reticulum by Using Reciprocally Selective Inhibitors. |
| Q64115448 | Selenium nanoparticles for targeted stroke therapy through modulation of inflammatory and metabolic signaling |
| Q89767052 | Sestrin2 protects dendritic cells against endoplasmic reticulum stress-related apoptosis induced by high mobility group box-1 protein |
| Q41669177 | Shiga Toxin Therapeutics: Beyond Neutralization. |
| Q55253157 | Significance of prohibitin domain family in tumorigenesis and its implication in cancer diagnosis and treatment. |
| Q89622503 | Spliced XBP1 Levels Determine Sensitivity of Multiple Myeloma Cells to Proteasome Inhibitor Bortezomib Independent of the Unfolded Protein Response Mediator GRP78 |
| Q34548166 | Spoxazomicin D and Oxachelin C, Potent Neuroprotective Carboxamides from the Appalachian Coal Fire-Associated Isolate Streptomyces sp. RM-14-6. |
| Q36261258 | Stably Expressed Genes Involved in Basic Cellular Functions |
| Q47221291 | Stimulator of Interferon Genes Deficiency in Acute Exacerbation of Idiopathic Pulmonary Fibrosis |
| Q59813440 | Stress Coping Strategies in the Heart: An Integrated View |
| Q64102473 | Structure and Molecular Mechanism of ER Stress Signaling by the Unfolded Protein Response Signal Activator IRE1 |
| Q89595739 | Systemic hypoxia led to little retinal neuronal loss and dramatic optic nerve glial response |
| Q99632509 | T-type calcium channel blockade induces apoptosis in C2C12 myotubes and skeletal muscle via endoplasmic reticulum stress activation |
| Q26740517 | Targeting p97 to Disrupt Protein Homeostasis in Cancer |
| Q55062312 | Targeting the Endoplasmic Reticulum Unfolded Protein Response to Counteract the Oxidative Stress-Induced Endothelial Dysfunction. |
| Q39232751 | Targeting the unfolded protein response in cancer |
| Q51126544 | Taurine ameliorated homocysteine-induced H9C2 cardiomyocyte apoptosis by modulating endoplasmic reticulum stress. |
| Q59360846 | The Crosstalk of Endoplasmic Reticulum (ER) Stress Pathways with NF-κB: Complex Mechanisms Relevant for Cancer, Inflammation and Infection |
| Q60923381 | The ER Stress Inducer l-Azetidine-2-Carboxylic Acid Elevates the Levels of Phospho-eIF2α and of LC3-II in a Ca-Dependent Manner |
| Q48190393 | The MTM1-UBQLN2-HSP complex mediates degradation of misfolded intermediate filaments in skeletal muscle. |
| Q93190124 | The Mitochondria-Endoplasmic Reticulum Contacts and Their Critical Role in Aging and Age-Associated Diseases |
| Q54987342 | The Neuroprotection of Low-Dose Morphine in Cellular and Animal Models of Parkinson's Disease Through Ameliorating Endoplasmic Reticulum (ER) Stress and Activating Autophagy. |
| Q41953903 | The Sec61 translocon limits IRE1α signaling during the unfolded protein response. |
| Q89693596 | The UPR preserves mature oligodendrocyte viability and function in adults by regulating autophagy of PLP |
| Q39431986 | The Unfolded Protein Response in the Immune Cell Development: Putting the Caretaker in the Driving Seat |
| Q39249695 | The Unfolded Protein Response: At the Intersection between Endoplasmic Reticulum Function and Mitochondrial Bioenergetics |
| Q57792065 | The cyclic phosphodiesterase CNP and RNA cyclase RtcA fine-tune noncanonical XBP1 splicing during ER stress |
| Q47236787 | The endoplasmic reticulum-residing chaperone BiP is short-lived and metabolized through N-terminal arginylation. |
| Q99593502 | The integrated UPR and ERAD in oligodendrocytes maintains myelin thickness in adults by regulating myelin protein translation |
| Q38954583 | The integrated stress response. |
| Q90407132 | The mammalian cytosolic thioredoxin reductase pathway acts via a membrane protein to reduce ER-localised proteins |
| Q48043703 | The metabolic ER stress sensor IRE1α suppresses alternative activation of macrophages and impairs energy expenditure in obesity |
| Q59339809 | The physiology of foamy phagocytes in multiple sclerosis |
| Q38825911 | The role of ER stress in lipid metabolism and lipotoxicity |
| Q29248713 | The unfolded protein response in immunity and inflammation |
| Q52730972 | The unfolded protein response in ischemic heart disease. |
| Q50026168 | The unfolded protein response regulator ATF6 promotes mesodermal differentiation. |
| Q39229321 | Therapeutics for APOL1 nephropathies: putting out the fire in the podocyte |
| Q42284692 | Together JUN and DDIT3 (CHOP) control retinal ganglion cell death after axonal injury |
| Q38821270 | Toxicogenomic module associations with pathogenesis: a network-based approach to understanding drug toxicity |
| Q47304202 | Transcription Factor C/EBP Homologous Protein in Health and Diseases. |
| Q47738000 | Two common human CLDN5 alleles encode different open reading frames but produce one protein isoform |
| Q91732402 | Two pools of IRE1α in cardiac and skeletal muscle cells |
| Q91152200 | UPR proteins IRE1 and PERK switch BiP from chaperone to ER stress sensor |
| Q52374464 | Understanding the Unfolded Protein Response in the Pathogenesis of Asthma. |
| Q64883325 | Unfolded Protein Response (UPR) in Survival, Dormancy, Immunosuppression, Metastasis, and Treatments of Cancer Cells. |
| Q91782525 | Unfolded Protein Response Differentially Regulates TLR4-Induced Cytokine Expression in Distinct Macrophage Populations |
| Q50073383 | Unfolded Protein Response of the Endoplasmic Reticulum in Tumor Progression and Immunogenicity. |
| Q92154284 | Unification of Opposites between Two Antioxidant Transcription Factors Nrf1 and Nrf2 in Mediating Distinct Cellular Responses to the Endoplasmic Reticulum Stressor Tunicamycin |
| Q91690576 | Unraveling the Potential Role of Glutathione in Multiple Forms of Cell Death in Cancer Therapy |
| Q92228764 | Unstructured regions in IRE1α specify BiP-mediated destabilisation of the luminal domain dimer and repression of the UPR |
| Q52699081 | Up-regulation of golgi α-mannosidase IA and down-regulation of golgi α-mannosidase IC activates unfolded protein response during hepatocarcinogenesis. |
| Q94475248 | Update on the role of endoplasmic reticulum stress in asthma |
| Q49360155 | Urinary Angiogenin Reflects the Magnitude of Kidney Injury at the Infrahistologic Level |
| Q90589602 | Urinary ERdj3 and mesencephalic astrocyte-derived neutrophic factor identify endoplasmic reticulum stress in glomerular disease |
| Q37200271 | Vitamin E δ-tocotrienol triggers endoplasmic reticulum stress-mediated apoptosis in human melanoma cells |
| Q90283779 | What Is Next in This "Age" of Heme-Driven Pathology and Protection by Hemopexin? An Update and Links with Iron |
| Q51763128 | When nature's robots go rogue: exploring protein homeostasis dysfunction and the implications for understanding human aging disease pathologies. |
| Q39076278 | When proteostasis goes bad: Protein aggregation in the cell. |
| Q39196908 | Zebrafish in Toxicology and Environmental Health |
| Q91866101 | ZnO Nanoparticles Induced Male Reproductive Toxicity Based on the Effects on the Endoplasmic Reticulum Stress Signaling Pathway |
| Q61798209 | eIF5A inhibition influences T cell dynamics in the pancreatic microenvironment of the humanized mouse model of Type 1 Diabetes |
| Q38893853 | p62/SQSTM1-Dr. Jekyll and Mr. Hyde that prevents oxidative stress but promotes liver cancer |
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