ER homeostasis and autophagy

scientific article published on 12 December 2017

ER homeostasis and autophagy is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1042/EBC20170092
P932PMC publication ID5869861
P698PubMed publication ID29233873

P50authorSimon WilkinsonQ54933553
Matthew SmithQ57016178
P2860cites workXBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel diseaseQ22252318
ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPsQ24290776
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factorQ24292102
RAB26 and RAB3D are direct transcriptional targets of MIST1 that regulate exocrine granule maturationQ24293415
LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formationQ24294635
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeatsQ24298956
Phosphorylation of the autophagy receptor optineurin restricts Salmonella growthQ24304447
p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagyQ24312147
A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formationQ24315723
Autophagosomes form at ER-mitochondria contact sitesQ24322618
Regulation of endoplasmic reticulum turnover by selective autophagyQ24337913
One step at a time: endoplasmic reticulum-associated degradationQ24658302
XBP-1 regulates signal transduction, transcription factors and bone marrow colonization in B cellsQ24658399
The LIR motif - crucial for selective autophagyQ26825455
Disulfide bond formation in the mammalian endoplasmic reticulumQ26829235
A Role for Macro-ER-Phagy in ER Quality ControlQ27933769
Receptor-mediated selective autophagy degrades the endoplasmic reticulum and the nucleusQ27934756
Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradationQ28131669
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glandsQ28510479
Activation of an unfolded protein response during differentiation of antibody-secreting B cells.Q52113898
Plasma cells require autophagy for sustainable immunoglobulin production.Q53122740
Retention of mutant alpha(1)-antitrypsin Z in endoplasmic reticulum is associated with an autophagic responseQ73127387
Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1Q80979487
Protein misfolding in the endoplasmic reticulum as a conduit to human diseaseQ38704807
14-Deoxy-11,12-didehydroandrographolide induces DDIT3-dependent endoplasmic reticulum stress-mediated autophagy in T-47D breast carcinoma cellsQ38780448
Digesting the Expanding Mechanisms of AutophagyQ38799613
XBP1 Controls Maturation of Gastric Zymogenic Cells by Induction of MIST1 and Expansion of the Rough Endoplasmic ReticulumQ39659690
The adaptor protein p62/SQSTM1 targets invading bacteria to the autophagy pathway.Q39790194
Expression of influenza virus hemagglutinin activates transcription factor NF-kappa B.Q39869036
Paneth cells secrete lysozyme via secretory autophagy during bacterial infection of the intestine.Q40116335
Two endoplasmic reticulum-associated degradation (ERAD) systems for the novel variant of the mutant dysferlin: ubiquitin/proteasome ERAD(I) and autophagy/lysosome ERAD(II).Q40164655
Differential effects of endoplasmic reticulum stress-induced autophagy on cell survival.Q40202994
Sequential waves of functionally related proteins are expressed when B cells prepare for antibody secretionQ40669445
Hepatitis C virus and its protein NS4B activate the cancer-related STAT3 pathway via the endoplasmic reticulum overload responseQ40754024
Sequestosome 1/p62 Protein Is Associated with Autophagic Removal of Excess Hepatic Endoplasmic Reticulum in MiceQ41002544
Full length RTN3 regulates turnover of tubular endoplasmic reticulum via selective autophagyQ41059785
Autophagy regulates endoplasmic reticulum homeostasis and calcium mobilization in T lymphocytesQ41486560
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.Q42041480
Endoplasmic reticulum stress response mediated by the PERK-eIF2(alpha)-ATF4 pathway is involved in osteoblast differentiation induced by BMP2Q42094437
ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stressQ42518206
Impaired autophagy induces chronic atrophic pancreatitis in mice via sex- and nutrition-dependent processesQ46799950
CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER ProteostasisQ47241715
STING Senses Microbial Viability to Orchestrate Stress-Mediated Autophagy of the Endoplasmic Reticulum.Q47620008
Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recoveryQ48272400
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulumQ28512249
XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein ResponseQ28585314
Autophagy is activated for cell survival after endoplasmic reticulum stressQ29614485
Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulumQ29614500
Neuronal calcium signalingQ29614727
IRE1 signaling affects cell fate during the unfolded protein responseQ29615502
The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteriaQ29615619
Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injuryQ30544606
Paneth cells as a site of origin for intestinal inflammation.Q30559414
Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteinsQ33262919
Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein responseQ33264844
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5.Q33559643
Recent Insights into the Role of Unfolded Protein Response in ER Stress in Health and DiseaseQ33653691
Quality control autophagy degrades soluble ERAD-resistant conformers of the misfolded membrane protein GnRHRQ33803716
Endoplasmic reticulum of animal cells and its organization into structural and functional domainsQ34240633
A novel signal transduction pathway from the endoplasmic reticulum to the nucleus is mediated by transcription factor NF-kappa B.Q34313045
XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiationQ34345459
Protein folding and quality control in the endoplasmic reticulum: Recent lessons from yeast and mammalian cell systemsQ35160159
The roles of endoplasmic reticulum overload response induced by HCV and NS4B protein in human hepatocyte viability and virus replicationQ35393817
Endoplasmic reticulum stress triggers autophagyQ35690087
Pharmacological ER stress promotes hepatic lipogenesis and lipid droplet formationQ35747483
The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote MitophagyQ36118105
Basal autophagy maintains pancreatic acinar cell homeostasis and protein synthesis and prevents ER stressQ36300434
Structure and function of the ULK1 complex in autophagyQ36788728
Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomesQ37014368
Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2alpha) dephosphorylation in mammalian developmentQ37100863
Cocaine induces astrocytosis through ER stress-mediated activation of autophagyQ37141770
The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expressionQ37148513
Involvement of autophagy in trypsinogen activation within the pancreatic acinar cellsQ37203732
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagyQ37246125
XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell developmentQ37377432
Protein folding in the endoplasmic reticulumQ38103530
Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response.Q38311676
Ubiquitin-Dependent And Independent Signals In Selective AutophagyQ38599451
Extensive pancreas regeneration following acinar-specific disruption of Xbp1 in miceQ38625919
P275copyright licenseCreative Commons AttributionQ6905323
P6216copyright statuscopyrightedQ50423863
P433issue6
P921main subjectautophagyQ288322
cellQ7868
P304page(s)625-635
P577publication date2017-12-12
P1433published inEssays in BiochemistryQ15754041
P1476titleER homeostasis and autophagy
P478volume61

Reverse relations

cites work (P2860)
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