Up-regulation of golgi α-mannosidase IA and down-regulation of golgi α-mannosidase IC activates unfolded protein response during hepatocarcinogenesis.

scientific article published on 19 April 2017

Up-regulation of golgi α-mannosidase IA and down-regulation of golgi α-mannosidase IC activates unfolded protein response during hepatocarcinogenesis. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/HEP4.1032
P8608Fatcat IDrelease_xrbpqade6vfsvlmt5dvt74ds2u
P932PMC publication ID5721452
P698PubMed publication ID29404456

P50authorHorng-Dar WangQ52699125
P2093author name stringJeng-Wei Lu
Chiou-Hwa Yuh
Hsiao-Chen Tu
Yu-Ting Chou
Hua-Kuo Lin
Chong-Yi Liao
Shin-Lin Tsai
Wan-Yu Yang
Yung-Chun Hsiao
P2860cites workEndoplasmic reticulum stress and the inflammatory basis of metabolic diseaseQ24633352
Hepatocellular carcinoma: Where are we?Q26765182
Controversies regarding and perspectives on clinical utility of biomarkers in hepatocellular carcinomaQ26772324
Signal integration in the endoplasmic reticulum unfolded protein responseQ27860577
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008Q27860674
The role of gelatinase in hepatic metastasis of colorectal cancerQ28212758
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
Liver-specific expressions of HBx and src in the p53 mutant trigger hepatocarcinogenesis in zebrafishQ28534280
The transcriptional profiling of glycogenes associated with hepatocellular carcinoma metastasisQ28543071
The unfolded protein response: from stress pathway to homeostatic regulationQ29547396
New functions for the matrix metalloproteinases in cancer progressionQ29547738
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetesQ29615503
Tumorigenesis and the angiogenic switchQ29619849
Metastatic behaviour of primary human tumours in a zebrafish xenotransplantation modelQ30488255
Reduced expression of alpha-1,2-mannosidase I extends lifespan in Drosophila melanogaster and Caenorhabditis elegansQ34314089
Structure and function of Class I alpha 1,2-mannosidases involved in glycoprotein synthesis and endoplasmic reticulum quality controlQ34351319
Ribose-5-phosphate isomerase A regulates hepatocarcinogenesis via PP2A and ERK signaling.Q34449889
ERManI is a target of miR-125b and promotes transformation phenotypes in hepatocellular carcinoma (HCC)Q34938492
Mutation of N-linked glycosylation at Asn548 in CD133 decreases its ability to promote hepatoma cell growthQ36299773
Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposureQ36413970
World Cancer Report 2014. Geneva, Switzerland: World Health Organization, International Agency for Research on Cancer, WHO Press, 2015.Q36671054
Golgi-situated endoplasmic reticulum α-1, 2-mannosidase contributes to the retrieval of ERAD substrates through a direct interaction with γ-COP.Q36758411
N-glycan structure dictates extension of protein folding or onset of disposalQ36825595
Prevention of cancer by inhibiting agingQ37260020
Overexpression of endothelin 1 triggers hepatocarcinogenesis in zebrafish and promotes cell proliferation and migration through the AKT pathwayQ37453166
Protein N-glycosylation, protein folding, and protein quality control.Q37845738
Secretory protein biogenesis and traffic in the early secretory pathwayQ38080412
From seeing to believing: labelling strategies for in vivo cell-tracking experiments.Q38121541
1-Deoxymannojirimycin, the alpha1,2-mannosidase inhibitor, induced cellular endoplasmic reticulum stress in human hepatocarcinoma cell 7721.Q38314243
Identification of the common regulators for hepatocellular carcinoma induced by hepatitis B virus X antigen in a mouse model.Q38330894
Structure of mouse Golgi alpha-mannosidase IA reveals the molecular basis for substrate specificity among class 1 (family 47 glycosylhydrolase) alpha1,2-mannosidasesQ38342137
Protein misfolding in the endoplasmic reticulum as a conduit to human diseaseQ38704807
Mannosidase IA is in Quality Control Vesicles and Participates in Glycoprotein Targeting to ERAD.Q38775886
Emerging tale of UPR and cancer: an essentiality for malignancy.Q38954615
Hypoxia-induced metastasis model in embryonic zebrafishQ39624502
Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in miceQ39975807
Glyco-genes change expression in cancer through aberrant methylation.Q40079083
Stimulation of ERAD of misfolded null Hong Kong alpha1-antitrypsin by Golgi alpha1,2-mannosidasesQ40087924
Chemical chaperones reduce endoplasmic reticulum stress and prevent mutant HFE aggregate formationQ40108203
Unfolded protein response in hypothalamic cultures of wild-type and ATF6α-knockout miceQ40167265
Endoplasmic reticulum stress and the unfolded protein response regulate genomic cystic fibrosis transmembrane conductance regulator expressionQ40229391
Relations of the type and branch of surface N-glycans to cell adhesion, migration and integrin expressionsQ40540137
Studies toward new anti-cancer strategies based on alpha-mannosidase inhibitionQ42784063
Possible role of α-mannosidase and β-galactosidase in larynx cancerQ43121201
Pioglitazone reduces ER stress in the liver: direct monitoring of in vivo ER stress using ER stress-activated indicator transgenic mice.Q43269505
Hepatitis B virus X antigen and aflatoxin B1 synergistically cause hepatitis, steatosis and liver hyperplasia in transgenic zebrafish.Q45352156
Gene expression profiles for the prediction of progression-free survival in diffuse large B cell lymphoma: results of a DASL assayQ47705814
Inhibitors of carbohydrate processing: A new class of anticancer agents.Q53461334
Carbonoyloxy analogs of the anti-metastatic drug swainsonine. Activation in tumor cells by esterasesQ72607761
Prognostic relevance of glycosylation-associated genes in breast cancerQ87690838
P433issue3
P304page(s)230-247
P577publication date2017-04-19
P1433published inHepatology CommunicationsQ50817751
P1476titleUp-regulation of golgi α-mannosidase IA and down-regulation of golgi α-mannosidase IC activates unfolded protein response during hepatocarcinogenesis.
P478volume1

Reverse relations

cites work (P2860)
Q91588519A Novel AURKA Mutant-Induced Early-Onset Severe Hepatocarcinogenesis Greater than Wild-Type via Activating Different Pathways in Zebrafish
Q92377049Identification of Novel Anti-Liver Cancer Small Molecules with Better Therapeutic Index than Sorafenib via Zebrafish Drug Screening Platform
Q104617798Low molecular weight fucoidan inhibits hepatocarcinogenesis and nonalcoholic fatty liver disease in zebrafish via ASGR/STAT3/HNF4A signaling
Q92453384N-Glycan profiling of lung adenocarcinoma in patients at different stages of disease
Q91644604Omics-based Investigation of Diet-induced Obesity Synergized with HBx, Src, and p53 Mutation Accelerating Hepatocarcinogenesis in Zebrafish Model
Q64058658Swainsonine, an alpha-mannosidase inhibitor, may worsen cervical cancer progression through the increase in myeloid derived suppressor cells population
Q60312876α-1,2-Mannosidase MAN1C1 Inhibits Proliferation and Invasion of Clear Cell Renal Cell Carcinoma

Search more.