| scholarly article | Q13442814 |
| P50 | author | Dawid Krokowski | Q70112860 |
| P2093 | author name string | William C Merrick | |
| Antonis E Koromilas | |||
| Maria Hatzoglou | |||
| Mithu Majumder | |||
| Scot R Kimball | |||
| Bo-Jhih Guan | |||
| Christine L Schmotzer | |||
| P2860 | cites work | A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1 | Q24294219 |
| Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids | Q24306330 | ||
| ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation | Q53616050 | ||
| ER stress inhibits mTORC2 and Akt signaling through GSK-3β-mediated phosphorylation of rictor. | Q54610967 | ||
| Increased mTORC1 signaling UPRegulates stress | Q80877075 | ||
| Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway | Q24307790 | ||
| The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1 | Q24315566 | ||
| A novel mTOR-regulated phosphorylation site in elongation factor 2 kinase modulates the activity of the kinase and its binding to calmodulin | Q24599904 | ||
| mTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availability | Q24607244 | ||
| mTOR: from growth signal integration to cancer, diabetes and ageing | Q24633662 | ||
| mTOR signaling in growth control and disease | Q24634174 | ||
| A complex interplay between Akt, TSC2 and the two mTOR complexes | Q24655791 | ||
| Endoplasmic Reticulum Stress and Type 2 Diabetes | Q26864238 | ||
| Amino acids and mTORC1: from lysosomes to disease | Q27009377 | ||
| Signal integration in the endoplasmic reticulum unfolded protein response | Q27860577 | ||
| TSC2 mediates cellular energy response to control cell growth and survival | Q27860970 | ||
| Rag proteins regulate amino-acid-induced mTORC1 signalling. | Q27863397 | ||
| Regulation of translation initiation in eukaryotes: mechanisms and biological targets | Q28111696 | ||
| TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling | Q28131740 | ||
| Translational control is required for the unfolded protein response and in vivo glucose homeostasis | Q28204066 | ||
| Effect of TRB3 on insulin and nutrient-stimulated hepatic p70 S6 kinase activity | Q28255760 | ||
| Upstream and downstream of mTOR | Q28277365 | ||
| The role of TOR in autophagy regulation from yeast to plants and mammals | Q28289304 | ||
| Regulated translation initiation controls stress-induced gene expression in mammalian cells | Q28506388 | ||
| AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1 | Q28506431 | ||
| The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins | Q28507365 | ||
| Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha | Q28512201 | ||
| mTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1–JNK pathway | Q28583302 | ||
| Autophagy: Renovation of Cells and Tissues | Q29547206 | ||
| An integrated stress response regulates amino acid metabolism and resistance to oxidative stress | Q29547441 | ||
| The role of autophagy during the early neonatal starvation period | Q29547489 | ||
| Bidirectional transport of amino acids regulates mTOR and autophagy | Q29614476 | ||
| Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy | Q29615616 | ||
| MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB | Q30524356 | ||
| Paneth cells as a site of origin for intestinal inflammation. | Q30559414 | ||
| Evaluation of the endoplasmic reticulum-stress response in eIF2B-mutated lymphocytes and lymphoblasts from CACH/VWM patients | Q33722753 | ||
| eIF2alpha phosphorylation tips the balance to apoptosis during osmotic stress | Q33883278 | ||
| Control of translation initiation through integration of signals generated by hormones, nutrients, and exercise | Q34121427 | ||
| Amino acid signalling upstream of mTOR | Q34325138 | ||
| K63 polyubiquitination and activation of mTOR by the p62-TRAF6 complex in nutrient-activated cells | Q37677233 | ||
| Cell signaling in protein synthesis ribosome biogenesis and translation initiation and elongation | Q37726436 | ||
| mTOR signaling in protein homeostasis: less is more? | Q37873702 | ||
| Feedback on Fat: p62-mTORC1-Autophagy Connections | Q37955445 | ||
| Bidirectional crosstalk between endoplasmic reticulum stress and mTOR signaling | Q37996626 | ||
| New Insights into Translational Regulation in the Endoplasmic Reticulum Unfolded Protein Response | Q38005599 | ||
| Control of Oncogenesis by eIF2α Phosphorylation: Implications in PTEN and PI3K–Akt Signaling and Tumor Treatment | Q38120310 | ||
| A Central role for mTOR in lipid homeostasis | Q38131225 | ||
| Modulation of ecotropic murine retroviruses by N-linked glycosylation of the cell surface receptor/amino acid transporter. | Q38352848 | ||
| p62 is a key regulator of nutrient sensing in the mTORC1 pathway. | Q38666713 | ||
| Regulated in DNA damage and development 1 (REDD1) promotes cell survival during serum deprivation by sustaining repression of signaling through the mechanistic target of rapamycin in complex 1 (mTORC1). | Q39098298 | ||
| Stress-induced gene expression requires programmed recovery from translational repression | Q39735685 | ||
| Improvement of ER stress-induced diabetes by stimulating autophagy | Q39878625 | ||
| An upstream open reading frame regulates translation of GADD34 during cellular stresses that induce eIF2alpha phosphorylation | Q39897560 | ||
| Loss of the tuberous sclerosis complex tumor suppressors triggers the unfolded protein response to regulate insulin signaling and apoptosis | Q40002274 | ||
| mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice | Q41912848 | ||
| A novel tumour promoter, thapsigargin, transiently increases cytoplasmic free Ca2+ without generation of inositol phosphates in NG115-401L neuronal cells | Q41989793 | ||
| Induction of amino acid transport system A in rat hepatocytes is blocked by tunicamycin | Q42454980 | ||
| Phosphorylation of eIF2 directs ATF5 translational control in response to diverse stress conditions | Q42523594 | ||
| mTOR signaling regulates the processing of pre-rRNA in human cells | Q42562707 | ||
| AMPK-Dependent Phosphorylation of ULK1 Induces Autophagy | Q42684420 | ||
| ER stress negatively regulates AKT/TSC/mTOR pathway to enhance autophagy | Q43183361 | ||
| mTORC1 Signaling Aids in CADalyzing Pyrimidine Biosynthesis | Q45061367 | ||
| Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies | Q45067792 | ||
| Rapamycin induces feedback activation of Akt signaling through an IGF-1R-dependent mechanism | Q51803667 | ||
| Activation of calcium/calmodulin-dependent protein kinase II in obesity mediates suppression of hepatic insulin signaling. | Q34387308 | ||
| Regulation of global and specific mRNA translation by amino acids | Q34620316 | ||
| Distinct autophagosomal-lysosomal fusion mechanism revealed by thapsigargin-induced autophagy arrest | Q34630595 | ||
| The unfolded protein response in nutrient sensing and differentiation | Q34664763 | ||
| Phosphorylation of eIF2 Facilitates Ribosomal Bypass of an Inhibitory Upstream ORF to Enhance CHOP Translation | Q34719370 | ||
| Amino acid transport across mammalian intestinal and renal epithelia | Q34736025 | ||
| Dynamics of the degradation of ubiquitinated proteins by proteasomes and autophagy: association with sequestosome 1/p62. | Q35063122 | ||
| Amino acid transporters: roles in amino acid sensing and signalling in animal cells | Q35184476 | ||
| mTOR Signaling to Translation | Q35560378 | ||
| A Novel Feedback Loop Regulates the Response to Endoplasmic Reticulum Stress via the Cooperation of Cytoplasmic Splicing and mRNA Translation | Q35807258 | ||
| Activation of ER stress and mTORC1 suppresses hepatic sortilin-1 levels in obese mice. | Q35913725 | ||
| A unifying model for mTORC1-mediated regulation of mRNA translation. | Q35945036 | ||
| A novel function of eIF2alpha kinases as inducers of the phosphoinositide-3 kinase signaling pathway | Q35949097 | ||
| Role of amino acids in the translational control of protein synthesis in mammals | Q36013960 | ||
| PERK Utilizes Intrinsic Lipid Kinase Activity To Generate Phosphatidic Acid, Mediate Akt Activation, and Promote Adipocyte Differentiation | Q36023300 | ||
| Internal ribosome entry sites in cellular mRNAs: mystery of their existence. | Q36062950 | ||
| Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response | Q36322641 | ||
| Protein-folding homeostasis in the endoplasmic reticulum and nutritional regulation | Q36418004 | ||
| Eukaryotic initiation factor 2B and its role in alterations in mRNA translation that occur under a number of pathophysiological and physiological conditions | Q36557541 | ||
| ATF4-dependent transcription mediates signaling of amino acid limitation | Q36655003 | ||
| Differential control of the CCAAT/enhancer-binding protein beta (C/EBPbeta) products liver-enriched transcriptional activating protein (LAP) and liver-enriched transcriptional inhibitory protein (LIP) and the regulation of gene expression during the | Q36825517 | ||
| Eukaryotic initiation factor 2 phosphorylation and translational control in metabolism. | Q36830383 | ||
| Translational control and the unfolded protein response | Q36924278 | ||
| A self-defeating anabolic program leads to β-cell apoptosis in endoplasmic reticulum stress-induced diabetes via regulation of amino acid flux | Q36928959 | ||
| ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death. | Q36954378 | ||
| Coordinate regulation of ribosome biogenesis and function by the ribosomal protein S6 kinase, a key mediator of mTOR function. | Q37037473 | ||
| Inhibition of protein synthesis alters protein degradation through activation of protein kinase B (AKT) | Q37099725 | ||
| ATF4 is necessary and sufficient for ER stress-induced upregulation of REDD1 expression | Q37130845 | ||
| The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression | Q37148513 | ||
| mTORC1 phosphorylation sites encode their sensitivity to starvation and rapamycin | Q37166913 | ||
| Examination of a second node of translational control in the unfolded protein response | Q37168900 | ||
| Phosphorylation of eukaryotic translation initiation factor 2alpha coordinates rRNA transcription and translation inhibition during endoplasmic reticulum stress | Q37275199 | ||
| Amino acid transceptors: gate keepers of nutrient exchange and regulators of nutrient signaling | Q37374064 | ||
| Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells | Q37388595 | ||
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 18 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | endoplasmic reticulum | Q79927 |
| phosphorylation | Q242736 | ||
| P304 | page(s) | 12593-12611 | |
| P577 | publication date | 2014-03-19 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Translational control during endoplasmic reticulum stress beyond phosphorylation of the translation initiation factor eIF2α. | |
| P478 | volume | 289 |
| Q47315154 | A Unique ISR Program Determines Cellular Responses to Chronic Stress. |
| Q91826949 | Accurate annotation of human protein-coding small open reading frames |
| Q92162437 | Alternative Mechanisms of mRNA Translation Initiation in Cellular Stress Response and Cancer |
| Q92389524 | Amino Acid Biosynthesis Regulation during Endoplasmic Reticulum Stress Is Coupled to Protein Expression Demands |
| Q24701804 | Apoptosis, autophagy and unfolded protein response pathways in Arbovirus replication and pathogenesis |
| Q49843417 | Artesunate shows potent anti-tumor activity in B-cell lymphoma |
| Q33900742 | BNIP3 induction by hypoxia stimulates FASN-dependent free fatty acid production enhancing therapeutic potential of umbilical cord blood-derived human mesenchymal stem cells |
| Q35655815 | Chromosome-associated protein D3 promotes bacterial clearance in human intestinal epithelial cells by repressing expression of amino acid transporters |
| Q57022095 | Chronic starvation induces noncanonical pro-death stress granules |
| Q42156227 | Complementary Roles of GADD34- and CReP-Containing Eukaryotic Initiation Factor 2α Phosphatases during the Unfolded Protein Response |
| Q35859494 | Coordinated Regulation of the Neutral Amino Acid Transporter SNAT2 and the Protein Phosphatase Subunit GADD34 Promotes Adaptation to Increased Extracellular Osmolarity |
| Q92982936 | De novo transcriptome profile of coccolithophorid alga Emiliania huxleyi CCMP371 at different calcium concentrations with proteome analysis |
| Q47781422 | Dietary Methionine Restriction Regulates Liver Protein Synthesis and Gene Expression Independently of Eukaryotic Initiation Factor 2 Phosphorylation in Mice |
| Q36514597 | Differential dynamics of the mammalian mRNA and protein expression response to misfolding stress. |
| Q90051658 | Discovery of a redox thiol switch: implications for cellular energy metabolism |
| Q37603249 | ER stress inhibitor attenuates hearing loss and hair cell death in Cdh23erl/erl mutant mice |
| Q35671675 | Elongation Factor 1A-1 Is a Mediator of Hepatocyte Lipotoxicity Partly through Its Canonical Function in Protein Synthesis |
| Q26770193 | Endoplasmic reticulum stress: a novel mechanism and therapeutic target for cardiovascular diseases |
| Q38232251 | Endoplasmic reticulum stress: key promoter of rosacea pathogenesis |
| Q47647683 | Hyperammonemia and proteostasis in cirrhosis |
| Q40144941 | IL-4 up-regulates cyclooxygenase-1 expression in macrophages. |
| Q34756838 | Identification of small molecules that protect pancreatic β cells against endoplasmic reticulum stress-induced cell death |
| Q36485185 | Inadequate fine-tuning of protein synthesis and failure of amino acid homeostasis following inhibition of the ATPase VCP/p97 |
| Q64262860 | Long noncoding RNA DNAJC3-AS1 promotes osteosarcoma progression via its sense-cognate gene DNAJC3 |
| Q42707372 | Metabolic adaptation of skeletal muscle to hyperammonemia drives the beneficial effects of l-leucine in cirrhosis |
| Q26801523 | Milk--A Nutrient System of Mammalian Evolution Promoting mTORC1-Dependent Translation |
| Q57054615 | New insights into the cellular temporal response to proteostatic stress |
| Q37024512 | Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer |
| Q51141348 | Pharmacological inhibition of spinal cord injury-stimulated ribosomal biogenesis does not affect locomotor outcome |
| Q41579911 | Phosphorylation of the translation initiation factor eIF2α at serine 51 determines the cell fate decisions of Akt in response to oxidative stress |
| Q59358844 | Porcine Reproductive and Respiratory Syndrome Virus Infection Induces both eIF2α Phosphorylation-Dependent and -Independent Host Translation Shutoff |
| Q98205106 | Porcine reproductive and respiratory syndrome virus infection induces endoplasmic reticulum stress, facilitates virus replication, and contributes to autophagy and apoptosis |
| Q90136557 | Prolonged high-fat-diet feeding promotes non-alcoholic fatty liver disease and alters gut microbiota in mice |
| Q36520868 | Quantitative H2S-mediated protein sulfhydration reveals metabolic reprogramming during the integrated stress response |
| Q47129256 | Repeated bouts of resistance exercise with short recovery periods activates mTOR signaling, but not protein synthesis, in mouse skeletal muscle. |
| Q41823803 | Residues required for phosphorylation of translation initiation factor eIF2α under diverse stress conditions are divergent between yeast and human |
| Q101133299 | Retrograde signaling by a mtDNA-encoded non-coding RNA preserves mitochondrial bioenergetics |
| Q51809921 | Surviving Stress: Modulation of ATF4-Mediated Stress Responses in Normal and Malignant Cells. |
| Q38866745 | Targeting the hallmarks of cancer with therapy-induced endoplasmic reticulum (ER) stress. |
| Q37522950 | The C/ebp-Atf response element (CARE) location reveals two distinct Atf4-dependent, elongation-mediated mechanisms for transcriptional induction of aminoacyl-tRNA synthetase genes in response to amino acid limitation. |
| Q35816038 | The Unfolded Protein Response Triggers Site-Specific Regulatory Ubiquitylation of 40S Ribosomal Proteins |
| Q38954583 | The integrated stress response. |
| Q27027262 | The pathogenic role of persistent milk signaling in mTORC1- and milk-microRNA-driven type 2 diabetes mellitus |
| Q37354013 | Translational control of PML contributes to TNFα-induced apoptosis of MCF7 breast cancer cells and decreased angiogenesis in HUVECs |
| Q89811174 | UVB-dependent inhibition of lipin-1 protects against proinflammatory responses in human keratinocytes |
| Q91973686 | mTOR as a central regulator of lifespan and aging |
| Q36768697 | mTORC1 and CK2 coordinate ternary and eIF4F complex assembly |
| Q42316166 | α-Asarone blocks 7β-hydroxycholesterol-exposed macrophage injury through blocking elF2α phosphorylation and prompting beclin-1-dependent autophagy |
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