| scholarly article | Q13442814 |
| P50 | author | Graham D. Pavitt | Q38319672 |
| P2093 | author name string | Edith Gomez | |
| Sarah S Mohammad | |||
| P2860 | cites work | Mutational analysis of mammalian translation initiation factor 5 (eIF5): role of interaction between the beta subunit of eIF2 and eIF5 in eIF5 function in vitro and in vivo | Q22254065 |
| Eukaryotic initiation factor 2B: identification of multiple phosphorylation sites in the epsilon-subunit and their functions in vivo | Q24291550 | ||
| Identification of domains and residues within the epsilon subunit of eukaryotic translation initiation factor 2B (eIF2Bepsilon) required for guanine nucleotide exchange reveals a novel activation function promoted by eIF2B complex formation | Q24554201 | ||
| Identification of a regulatory subcomplex in the guanine nucleotide exchange factor eIF2B that mediates inhibition by phosphorylated eIF2 | Q24647789 | ||
| A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding | Q25938984 | ||
| Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Balpha complex | Q27632050 | ||
| The structure of the Escherichia coli EF-Tu.EF-Ts complex at 2.5 A resolution | Q27732595 | ||
| A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae | Q27860636 | ||
| eIF2 independently binds two distinct eIF2B subcomplexes that catalyze and regulate guanine-nucleotide exchange. | Q27930296 | ||
| A novel eIF2B-dependent mechanism of translational control in yeast as a response to fusel alcohols | Q27930611 | ||
| Eukaryotic translation initiation factor 5 functions as a GTPase-activating protein | Q27934712 | ||
| Evidence that GCD6 and GCD7, translational regulators of GCN4, are subunits of the guanine nucleotide exchange factor for eIF-2 in Saccharomyces cerevisiae | Q27937984 | ||
| Homologous segments in three subunits of the guanine nucleotide exchange factor eIF2B mediate translational regulation by phosphorylation of eIF2. | Q27938220 | ||
| Mutations in the GCD7 subunit of yeast guanine nucleotide exchange factor eIF-2B overcome the inhibitory effects of phosphorylated eIF-2 on translation initiation | Q27939935 | ||
| Multifunctional yeast high-copy-number shuttle vectors | Q28131605 | ||
| 5-Fluoroorotic acid as a selective agent in yeast molecular genetics | Q28131614 | ||
| Studies on the transformation of intact yeast cells by the LiAc/SS-DNA/PEG procedure | Q28131658 | ||
| Identification of domains within the epsilon-subunit of the translation initiation factor eIF2B that are necessary for guanine nucleotide exchange activity and eIF2B holoprotein formation | Q28138606 | ||
| GEFs: structural basis for their activation of small GTP-binding proteins | Q28141028 | ||
| Subunits of the translation initiation factor eIF2B are mutant in leukoencephalopathy with vanishing white matter | Q28204796 | ||
| Mutations in each of the five subunits of translation initiation factor eIF2B can cause leukoencephalopathy with vanishing white matter | Q28218053 | ||
| Regulated translation initiation controls stress-induced gene expression in mammalian cells | Q28506388 | ||
| Subunit assembly and guanine nucleotide exchange activity of eukaryotic initiation factor-2B expressed in Sf9 cells | Q28564610 | ||
| Regulation of guanine nucleotide exchange through phosphorylation of eukaryotic initiation factor eIF2alpha. Role of the alpha- and delta-subunits of eiF2b | Q28572395 | ||
| Gene-specific regulation by general translation factors | Q28611181 | ||
| Vectors for the inducible overexpression of glutathione S-transferase fusion proteins in yeast | Q29618547 | ||
| Eukaryotic translation initiation factor 5 (eIF5) acts as a classical GTPase-activator protein. | Q31882295 | ||
| Conserved bipartite motifs in yeast eIF5 and eIF2Bepsilon, GTPase-activating and GDP-GTP exchange factors in translation initiation, mediate binding to their common substrate eIF2. | Q33890632 | ||
| Tight binding of the phosphorylated alpha subunit of initiation factor 2 (eIF2alpha) to the regulatory subunits of guanine nucleotide exchange factor eIF2B is required for inhibition of translation initiation | Q33969048 | ||
| Minimum requirements for the function of eukaryotic translation initiation factor 2. | Q34612559 | ||
| Modulation of tRNA(iMet), eIF-2, and eIF-2B expression shows that GCN4 translation is inversely coupled to the level of eIF-2.GTP.Met-tRNA(iMet) ternary complexes | Q36555932 | ||
| Glycogen synthase kinase-3 is rapidly inactivated in response to insulin and phosphorylates eukaryotic initiation factor eIF-2B. | Q42811852 | ||
| Mechanism of elongation factor (EF)-Ts-catalyzed nucleotide exchange in EF-Tu. Contribution of contacts at the guanine base | Q43823922 | ||
| Role of the conserved aspartate and phenylalanine residues in prokaryotic and mitochondrial elongation factor Ts in guanine nucleotide exchange | Q71420824 | ||
| Mutational analysis of the roles of residues in Escherichia coli elongation factor Ts in the interaction with elongation factor Tu | Q74192462 | ||
| Invasion of the nucleotide snatchers: structural insights into the mechanism of G protein GEFs | Q77470794 | ||
| P433 | issue | 19 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | guanine | Q169313 |
| Translation initiation factor eIF2B catalytic subunit epsilon YDR211W | Q27547522 | ||
| P304 | page(s) | 5292-5301 | |
| P577 | publication date | 2002-10-01 | |
| P1433 | published in | The EMBO Journal | Q1278554 |
| P1476 | title | Characterization of the minimal catalytic domain within eIF2B: the guanine-nucleotide exchange factor for translation initiation | |
| P478 | volume | 21 |
| Q58698853 | A Promising Small Molecule for Vanishing White Matter Disease |
| Q38285158 | A new function and complexity for protein translation initiation factor eIF2B |
| Q40030572 | A novel mechanism for the control of translation initiation by amino acids, mediated by phosphorylation of eukaryotic initiation factor 2B. |
| Q48138474 | A presumed homologue of the regulatory subunits of eIF2B functions as ribose-1,5-bisphosphate isomerase in Pyrococcus horikoshii OT3. |
| Q28485114 | A yeast purification system for human translation initiation factors eIF2 and eIF2Bε and their use in the diagnosis of CACH/VWM disease |
| Q37012797 | Activation of the mammalian target of rapamycin complex 1 is both necessary and sufficient to stimulate eukaryotic initiation factor 2Bvarepsilon mRNA translation and protein synthesis |
| Q38027959 | Adaptation to stress in yeast: to translate or not? |
| Q92162437 | Alternative Mechanisms of mRNA Translation Initiation in Cellular Stress Response and Cancer |
| Q35065850 | An eIF5/eIF2 complex antagonizes guanine nucleotide exchange by eIF2B during translation initiation |
| Q34118639 | Archaeal aIF2B interacts with eukaryotic translation initiation factors eIF2alpha and eIF2Balpha: Implications for aIF2B function and eIF2B regulation. |
| Q38934354 | Architecture of the eIF2B regulatory subcomplex and its implications for the regulation of guanine nucleotide exchange on eIF2. |
| Q35749160 | Biochemical effects of mutations in the gene encoding the alpha subunit of eukaryotic initiation factor (eIF) 2B associated with Vanishing White Matter disease |
| Q36092079 | Change in nutritional status modulates the abundance of critical pre-initiation intermediate complexes during translation initiation in vivo |
| Q42412345 | Critical contacts between the eukaryotic initiation factor 2B (eIF2B) catalytic domain and both eIF2beta and -2gamma mediate guanine nucleotide exchange. |
| Q38954159 | Crystal structure of eIF2B and insights into eIF2-eIF2B interactions |
| Q27704065 | Crystal structure of eukaryotic translation initiation factor 2B |
| Q36922857 | Crystal structure of the C-terminal domain of the ɛ subunit of human translation initiation factor eIF2B. |
| Q42831942 | Defective translational control facilitates vesicular stomatitis virus oncolysis |
| Q33633701 | Differential regulation of CHOP translation by phosphorylated eIF4E under stress conditions |
| Q46979602 | Direct binding of translation initiation factor eIF2gamma-G domain to its GTPase-activating and GDP-GTP exchange factors eIF5 and eIF2B epsilon |
| Q24295527 | EIF2B5 mutations compromise GFAP+ astrocyte generation in vanishing white matter leukodystrophy |
| Q37491704 | Enhanced eIF1 binding to the 40S ribosome impedes conformational rearrangements of the preinitiation complex and elevates initiation accuracy. |
| Q36830383 | Eukaryotic initiation factor 2 phosphorylation and translational control in metabolism. |
| Q36557541 | Eukaryotic initiation factor 2B and its role in alterations in mRNA translation that occur under a number of pathophysiological and physiological conditions |
| Q34558627 | Eukaryotic translation initiation factor 5 is critical for integrity of the scanning preinitiation complex and accurate control of GCN4 translation. |
| Q38853906 | Evolution of the archaeal and mammalian information processing systems: towards an archaeal model for human disease |
| Q44755191 | Functional molecular mapping of archaeal translation initiation factor 2. |
| Q41982274 | Identification of intersubunit domain interactions within eukaryotic initiation factor (eIF) 2B, the nucleotide exchange factor for translation initiation |
| Q28730770 | Identification of residues that underpin interactions within the eukaryotic initiation factor (eIF2) 2B complex |
| Q39001148 | In vivo evidence that eIF3 stays bound to ribosomes elongating and terminating on short upstream ORFs to promote reinitiation |
| Q36875727 | Mechanism and Regulation of Protein Synthesis in Saccharomyces cerevisiae |
| Q24634138 | Mechanisms of translational regulation by a human eIF5-mimic protein |
| Q39028088 | More than just scanning: the importance of cap-independent mRNA translation initiation for cellular stress response and cancer. |
| Q24629691 | Mutations causing childhood ataxia with central nervous system hypomyelination reduce eukaryotic initiation factor 2B complex formation and activity |
| Q24323177 | Mutations linked to leukoencephalopathy with vanishing white matter impair the function of the eukaryotic initiation factor 2B complex in diverse ways |
| Q47112435 | Novel mechanisms of eIF2B action and regulation by eIF2α phosphorylation. |
| Q34548962 | Nutrient sensing and signaling in the yeast Saccharomyces cerevisiae |
| Q36965192 | Purification of FLAG-tagged eukaryotic initiation factor 2B complexes, subcomplexes, and fragments from Saccharomyces cerevisiae |
| Q50048320 | Regulation of Sensing, Transportation, and Catabolism of Nitrogen Sources in Saccharomyces cerevisiae |
| Q28111696 | Regulation of translation initiation in eukaryotes: mechanisms and biological targets |
| Q45945811 | Severity of vanishing white matter disease does not correlate with deficits in eIF2B activity or the integrity of eIF2B complexes. |
| Q64986003 | Structural basis for the inhibition of translation through eIF2α phosphorylation. |
| Q27642799 | Structure of the catalytic fragment of translation initiation factor 2B and identification of a critically important catalytic residue |
| Q88219676 | Structure of the nucleotide exchange factor eIF2B reveals mechanism of memory-enhancing molecule |
| Q37355995 | The adenovirus E1B 55-kilodalton and E4 open reading frame 6 proteins limit phosphorylation of eIF2alpha during the late phase of infection |
| Q38748930 | The alpha subunit of eukaryotic initiation factor 2B (eIF2B) is required for eIF2-mediated translational suppression of vesicular stomatitis virus |
| Q34190226 | The beta/Gcd7 subunit of eukaryotic translation initiation factor 2B (eIF2B), a guanine nucleotide exchange factor, is crucial for binding eIF2 in vivo |
| Q34289214 | The mechanism of eukaryotic translation initiation: new insights and challenges |
| Q37726434 | The molecular basis of translational control |
| Q64057211 | The structural basis of translational control by eIF2 phosphorylation |
| Q35083069 | Unique classes of mutations in the Saccharomyces cerevisiae G-protein translation elongation factor 1A suppress the requirement for guanine nucleotide exchange. |
| Q34651274 | VSV-tumor selective replication and protein translation |
| Q51976069 | Yeast phenotypic assays on translational control. |
| Q28833240 | eIF2 interactions with initiator tRNA and eIF2B are regulated by post-translational modifications and conformational dynamics |
| Q27933768 | eIF2B is a decameric guanine nucleotide exchange factor with a γ2ε2 tetrameric core |
| Q50100283 | eIF2B mechanisms of action and regulation: a thermodynamic view |
| Q37424689 | eIF2B promotes eIF5 dissociation from eIF2*GDP to facilitate guanine nucleotide exchange for translation initiation |
| Q39617540 | eIF2β is critical for eIF5-mediated GDP-dissociation inhibitor activity and translational control |
Search more.