Expanding Role of Ubiquitin in Translational Control

scientific article published on 09 February 2020

Expanding Role of Ubiquitin in Translational Control is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.3390/IJMS21031151
P932PMC publication ID7037965
P698PubMed publication ID32050486

P50authorAustin O MadukaQ89682231
P2093author name stringToshifumi Inada
Shannon E Dougherty
Gustavo M Silva
P2860cites workMechanisms and functions of ribosome-associated protein quality controlQ92802742
Polyubiquitin Chains Linked by Lysine Residue 48 (K48) Selectively Target Oxidized Proteins In VivoQ93092366
Site-Specific K63 Ubiquitinomics Provides Insights into Translation Regulation under StressQ93389372
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot projectQ21061203
Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signalingQ21144354
Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2alpha kinaseQ22010589
Ubiquitin is phosphorylated by PINK1 to activate parkinQ24296532
The Protein Data BankQ24515306
RNA-Seq: a revolutionary tool for transcriptomicsQ24596169
Compilation of transcription regulating proteinsQ24599406
HECT and RING finger families of E3 ubiquitin ligases at a glanceQ24599672
Proposed role of ATP in protein breakdown: conjugation of protein with multiple chains of the polypeptide of ATP-dependent proteolysisQ24621105
Systematic and quantitative assessment of the ubiquitin-modified proteomeQ24634631
Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradationQ24643067
Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymesQ24645701
Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profilingQ24651977
Ubiquitin signaling in immune responsesQ26751376
Ubiquitin modificationsQ26751380
E2 enzymes: more than just middle menQ26752818
Ubiquitin chain diversity at a glanceQ26767117
Ribosome-associated protein quality controlQ26770828
Targeting the ubiquitin pathway for cancer treatmentQ26866185
ROS-dependent signal transductionQ27005917
The structure of the eukaryotic ribosome at 3.0 Å resolutionQ27675638
Regulation of A20 and other OTU deubiquitinases by reversible oxidationQ27676707
Structure of ubiquitin refined at 1.8 A resolutionQ27728512
A relationship between protein stability and protein functionQ27730341
RING domain E3 ubiquitin ligasesQ27860546
Genomic expression programs in the response of yeast cells to environmental changesQ27860823
Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteinsQ27861094
Dynamic ubiquitination of the mitogen-activated protein kinase kinase (MAPKK) Ste7 determines mitogen-activated protein kinase (MAPK) specificity.Q27930260
UBA 1: an essential yeast gene encoding ubiquitin-activating enzymeQ27931184
Ubp3 requires a cofactor, Bre5, to specifically de-ubiquitinate the COPII protein, Sec23.Q27932632
Cdc48 and Ufd3, new partners of the ubiquitin protease Ubp3, are required for ribophagyQ27932851
Rad6-Bre1-mediated histone H2B ubiquitylation modulates the formation of double-strand breaks during meiosisQ27932934
Analysis of the deubiquitinating enzymes of the yeast Saccharomyces cerevisiaeQ27932938
The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzymeQ27933609
Protein synthesis. Rqc2p and 60S ribosomal subunits mediate mRNA-independent elongation of nascent chainsQ27933843
Bre1, an E3 ubiquitin ligase required for recruitment and substrate selection of Rad6 at a promoterQ27933859
A convergence of rRNA and mRNA quality control pathways revealed by mechanistic analysis of nonfunctional rRNA decayQ27934461
Role of a ribosome-associated E3 ubiquitin ligase in protein quality controlQ27936843
Yeast DNA repair proteins Rad6 and Rad18 form a heterodimer that has ubiquitin conjugating, DNA binding, and ATP hydrolytic activitiesQ27938794
Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin proteaseQ27938863
K63 polyubiquitination is a new modulator of the oxidative stress responseQ27938946
A role for ubiquitin in the clearance of nonfunctional rRNAsQ27939416
Cdc48/p97 promotes degradation of aberrant nascent polypeptides bound to the ribosomeQ27939735
The tails of ubiquitin precursors are ribosomal proteins whose fusion to ubiquitin facilitates ribosome biogenesisQ27939801
40S subunit dissociation and proteasome-dependent RNA degradation in nonfunctional 25S rRNA decayQ27940372
Regulation of translation initiation in eukaryotes: mechanisms and biological targetsQ28111696
Correlation between protein and mRNA abundance in yeastQ28137554
The ubiquitin codeQ28265104
Ubiquitin chain conformation regulates recognition and activity of interacting proteinsQ28280440
Regulatory mechanisms involved in the control of ubiquitin homeostasisQ28280583
A genomic and functional inventory of deubiquitinating enzymesQ28284911
Characterization of the yeast transcriptomeQ28302110
The ubiquitin-proteasome systemQ28305844
Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme chargingQ28307753
A mouse forward genetics screen identifies LISTERIN as an E3 ubiquitin ligase involved in neurodegenerationQ28585283
The catalytic mechanism of guanine nucleotide exchange factor action and competitive inhibition by phosphorylated eukaryotic initiation factor 2Q28608922
Listerin-dependent nascent protein ubiquitination relies on ribosome subunit dissociationQ28675845
Ribosomal proteins produced in excess are degraded by the ubiquitin-proteasome systemQ28828325
Structural mechanism for the recognition and ubiquitination of a single nucleosome residue by Rad6-Bre1Q28829129
ZNF598 and RACK1 Regulate Mammalian Ribosome-Associated Quality Control Function by Mediating Regulatory 40S Ribosomal UbiquitylationQ28975780
Eukaryotic ribosome biogenesis at a glanceQ29542167
A proteomics approach to understanding protein ubiquitinationQ29547312
Ubiquitin-binding domainsQ29614358
Proteasomes and their kin: proteases in the machine ageQ29614359
A 26 S protease subunit that binds ubiquitin conjugatesQ29614362
TRANSFAC: an integrated system for gene expression regulationQ29614502
Translational regulation of GCN4 and the general amino acid control of yeastQ29615275
Functional specificity among ribosomal proteins regulates gene expressionQ39666047
The Cost of Protein Production.Q40150659
Selectivity of the ubiquitin pathway for oxidatively modified proteins: relevance to protein precipitation diseasesQ40385382
Aging, energy, and oxidative stress in neurodegenerative diseases.Q40478731
Binding of polyubiquitin chains to ubiquitin-associated (UBA) domains of HHR23A.Q40488188
Cell cycle-regulated modification of the ribosome by a variant multiubiquitin chainQ40863875
The E3 ubiquitin ligase and RNA-binding protein ZNF598 orchestrates ribosome quality control of premature polyadenylated mRNAsQ40975929
Receptor for activated C kinase 1 stimulates nascent polypeptide-dependent translation arrestQ41108626
Ubiquitination of stalled ribosome triggers ribosome-associated quality controlQ41170038
Control of messenger RNA stability in higher eukaryotesQ41293585
Degradation of Redox-Sensitive Proteins including Peroxiredoxins and DJ-1 is Promoted by Oxidation-induced Conformational Changes and UbiquitinationQ41323221
The repertoires of ubiquitinating and deubiquitinating enzymes in eukaryotic genomesQ41436775
The Gcn4 transcription factor reduces protein synthesis capacity and extends yeast lifespanQ41630273
Targeting of substrates to the 26S proteasomeQ41641565
Functional specialization of ribosomes?Q41859001
Linkage-specific avidity defines the lysine 63-linked polyubiquitin-binding preference of rap80.Q42080792
Translation drives mRNA quality controlQ42093433
Mechanism of Lys48-linked polyubiquitin chain recognition by the Mud1 UBA domainQ42139176
Ribosome-associated Asc1/RACK1 is required for endonucleolytic cleavage induced by stalled ribosome at the 3' end of nonstop mRNAQ42140941
Importance of catalase in the adaptive response to hydrogen peroxide: analysis of acatalasaemic Saccharomyces cerevisiaeQ42159933
Crt10 directs the cullin-E3 ligase Rtt101 to nonfunctional 25S rRNA decayQ42176308
The ubiquitin hybrid gene UBA52 regulates ubiquitination of ribosome and sustains embryonic developmentQ42371018
Translation of the poly(A) tail plays crucial roles in nonstop mRNA surveillance via translation repression and protein destabilization by proteasome in yeastQ42924383
Principles of ER cotranslational translocation revealed by proximity-specific ribosome profilingQ43093001
Phosphorylation of ubiquitin at Ser65 affects its polymerization, targets, and proteome-wide turnoverQ43244956
RNA interference of valosin-containing protein (VCP/p97) reveals multiple cellular roles linked to ubiquitin/proteasome-dependent proteolysisQ44681202
Neurodegenerative diseases and oxidative stressQ44805871
Identification of GCN2 as new redox regulator for oxidative stress prevention in vivoQ44970855
The absolute quantification strategy: a general procedure for the quantification of proteins and post-translational modificationsQ45275572
The Mammalian Ribo-interactome Reveals Ribosome Functional Diversity and HeterogeneityQ47210447
Ubiquitin signaling and autophagyQ47349935
Ribosome Collision Is Critical for Quality Control during No-Go DecayQ47752031
Ub-ProT reveals global length and composition of protein ubiquitylation in cellsQ48096070
Proteomic Analysis Identifies Ribosome Reduction as an Effective Proteotoxic Stress Response.Q36444204
Deubiquitinases as a signaling target of oxidative stressQ36501472
Protein monoubiquitylation: targets and diverse functionsQ36554464
Reversible inactivation of deubiquitinases by reactive oxygen species in vitro and in cells.Q36737013
Gcn4 is required for the response to peroxide stress in the yeast Saccharomyces cerevisiae.Q36739878
Mammalian Heat Shock Response and Mechanisms Underlying Its Genome-wide Transcriptional RegulationQ36782793
Heat shock and oxygen radicals stimulate ubiquitin-dependent degradation mainly of newly synthesized proteinsQ36843138
Absolute quantification of protein and post-translational modification abundance with stable isotope-labeled synthetic peptidesQ37078446
RNA-binding proteins and post-transcriptional gene regulationQ37110656
Structure and function of the yeast listerin (Ltn1) conserved N-terminal domain in binding to stalled 60S ribosomal subunitsQ37126852
Polyubiquitin chains: functions, structures, and mechanismsQ37148338
Ubiquitylation by the Ltn1 E3 ligase protects 60S ribosomes from starvation-induced selective autophagyQ37721756
Regulation of translation by hydrogen peroxideQ37815199
No-go decay: a quality control mechanism for RNA in translationQ37940386
RINGs hold the key to ubiquitin transferQ37966409
Linear ubiquitination: a newly discovered regulator of cell signallingQ38075345
The demographics of the ubiquitin systemQ38439051
Components of ubiquitin-protein ligase system. Resolution, affinity purification, and role in protein breakdownQ38583853
UCSF ChimeraX: Meeting Modern Challenges in Visualization and Analysis.Q38677893
Highly Multiplexed Quantitative Mass Spectrometry Analysis of Ubiquitylomes.Q38736515
The increasing complexity of the ubiquitin codeQ38845500
Proteome complexity and the forces that drive proteome imbalance.Q38954697
The emerging complexity of ubiquitin architectureQ39052139
RNA modifications and structures cooperate to guide RNA-protein interactions.Q39112521
Activity-based probes for the ubiquitin conjugation-deconjugation machinery: new chemistries, new tools, and new insightsQ39135148
Ribosome profiling and dynamic regulation of translation in mammalsQ39211313
Ubiquitin and Parkinson's disease through the looking glass of geneticsQ39241365
Oxidative stress, protein damage and repair in bacteria.Q39249467
An emerging role for the ribosome as a nexus for post-translational modificationsQ39264675
Mechanisms of Deubiquitinase Specificity and Regulation.Q39302629
Global translational responses to oxidative stress impact upon multiple levels of protein synthesis.Q39348564
The E2 ubiquitin conjugase Rad6 is required for the ArgR/Mcm1 repression of ARG1 transcriptionQ39406784
A sampling of the yeast proteomeQ39448401
A conserved quality-control pathway that mediates degradation of unassembled ribosomal proteins.Q39463298
Heterogeneous Ribosomes Preferentially Translate Distinct Subpools of mRNAs Genome-wide.Q50434557
Translation factor control of ribosome conformation during start codon selection.Q51984242
Structure and Function of the 26S Proteasome.Q52322457
TOM1p, a yeast hect-domain protein which mediates transcriptional regulation through the ADA/SAGA coactivator complexes.Q52532015
Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types.Q52721693
Dom34:hbs1 plays a general role in quality-control systems by dissociation of a stalled ribosome at the 3' end of aberrant mRNA.Q53174214
Failure of RQC machinery causes protein aggregation and proteotoxic stress.Q53794775
Signaling pathways involved in the regulation of mRNA translation.Q54118148
Ubiquitination regulation of inflammatory responses through NF-κB pathway.Q55328184
Ubiquitin and control of transcriptionQ56802340
ZNF598 Is a Quality Control Sensor of Collided RibosomesQ57190424
Substrate-engaged 26 proteasome structures reveal mechanisms for ATP-hydrolysis-driven translocationQ57477239
UbiSite approach for comprehensive mapping of lysine and N-terminal ubiquitination sitesQ57979502
Substrate-engaged 26S proteasome structures reveal mechanisms for ATP-hydrolysis–driven translocationQ58024045
The deubiquitinating enzyme Ubp2 modulates Rsp5-dependent Lys63-linked polyubiquitin conjugates in Saccharomyces cerevisiaeQ79209223
The endonuclease Cue2 cleaves mRNAs at stalled ribosomes during No Go DecayQ83232241
NUFIP1 is a ribosome receptor for starvation-induced ribophagyQ88487910
New Insights into Ribosome Structure and FunctionQ89107222
Post-translational regulation of ubiquitin signalingQ89997332
Poly-ubiquitin profile in Alzheimer disease brainQ90024352
Heterogeneous translational landscape of the endoplasmic reticulum revealed by ribosome proximity labeling and transcriptome analysisQ90024723
Translation deregulation in human diseaseQ90428516
The Discovery of Ribosome Heterogeneity and Its Implications for Gene Regulation and Organismal LifeQ90740513
Collided ribosomes form a unique structural interface to induce Hel2-driven quality control pathwaysQ90890979
The Impact of Oxidative Stress on Ribosomes: From Injury to RegulationQ91097348
Oxidation and alkylation stresses activate ribosome-quality controlQ91825235
Branching Out: Improved Signaling by Heterotypic Ubiquitin ChainsQ91837029
Extensive post-transcriptional buffering of gene expression in the response to severe oxidative stress in baker's yeastQ92266393
CAT tails drive degradation of stalled polypeptides on and off the ribosomeQ92325284
Sequential Ubiquitination of Ribosomal Protein uS3 Triggers the Degradation of Non-functional 18S rRNAQ92505681
Ribosome Abundance Control Via the Ubiquitin-Proteasome System and AutophagyQ92720022
Autophagy and metabolismQ29615974
Physiological functions of the HECT family of ubiquitin ligasesQ29617293
Nonproteolytic functions of ubiquitin in cell signalingQ29617294
Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosisQ29617390
What is oxidative stress?Q33849762
Global signatures of protein and mRNA expression levelsQ33874396
Ubiquitin as a degradation signalQ33937351
Role of oxidative stress in cardiovascular diseasesQ33953686
Using the transcriptome to annotate the genomeQ33958846
Ubiquitin genes as a paradigm of concerted evolution of tandem repeatsQ34048719
Global analysis of lysine ubiquitination by ubiquitin remnant immunoaffinity profilingQ34159143
Ribosome profiling reveals pervasive translation outside of annotated protein-coding genesQ34435177
Ubiquitin and control of transcriptionQ34463020
Mechanisms of In Vivo Ribosome Maintenance Change in Response to Nutrient SignalsQ34546939
Potential roles for ubiquitin and the proteasome during ribosome biogenesisQ34718323
Linear ubiquitin fusion to Rps31 and its subsequent cleavage are required for the efficient production and functional integrity of 40S ribosomal subunitsQ34942783
Ubiquitin-proteasome pathway and cellular responses to oxidative stressQ35027877
Structure and assembly pathway of the ribosome quality control complexQ35064391
Ubiquitin acetylation inhibits polyubiquitin chain elongationQ35084540
Inhibiting K63 polyubiquitination abolishes no-go type stalled translation surveillance in Saccharomyces cerevisiaeQ35613568
The Unfolded Protein Response Triggers Site-Specific Regulatory Ubiquitylation of 40S Ribosomal ProteinsQ35816038
Diversity and selectivity in mRNA translation on the endoplasmic reticulumQ35827837
Rkr1/Ltn1 Ubiquitin Ligase-mediated Degradation of Translationally Stalled Endoplasmic Reticulum ProteinsQ35883810
The Proteasome Distinguishes between Heterotypic and Homotypic Lysine-11-Linked Polyubiquitin ChainsQ35943032
Multiubiquitylation by E4 enzymes: 'one size' doesn't fit all.Q36092032
The ubiquitin-proteasome system of Saccharomyces cerevisiaeQ36268060
Proteasome-associated proteins: regulation of a proteolytic machineQ36275413
Efficient APC/C substrate degradation in cells undergoing mitotic exit depends on K11 ubiquitin linkagesQ36336999
Genome-wide ribosome profiling reveals complex translational regulation in response to oxidative stressQ36378323
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue3
P577publication date2020-02-09
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleExpanding Role of Ubiquitin in Translational Control
P478volume21

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