| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1049921236 |
| P356 | DOI | 10.1038/NCB3358 |
| P698 | PubMed publication ID | 27230526 |
| P50 | author | Michael Rape | Q55163233 |
| P2093 | author name string | Richard Yau | |
| P2860 | cites work | PINK1 is selectively stabilized on impaired mitochondria to activate Parkin | Q21145802 |
| TAK1 is a ubiquitin-dependent kinase of MKK and IKK | Q24291454 | ||
| Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65 | Q24292901 | ||
| The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis | Q24293633 | ||
| OTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitin | Q24294696 | ||
| PARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's disease | Q24294809 | ||
| The mechanism of linkage-specific ubiquitin chain elongation by a single-subunit E2 | Q24294888 | ||
| K33-Linked Polyubiquitination of Coronin 7 by Cul3-KLHL20 Ubiquitin E3 Ligase Regulates Protein Trafficking | Q24295450 | ||
| TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes | Q24295574 | ||
| Molecular determinants of polyubiquitin linkage selection by an HECT ubiquitin ligase | Q34547388 | ||
| Certain pairs of ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) synthesize nondegradable forked ubiquitin chains containing all possible isopeptide linkages. | Q34617875 | ||
| Quantitative proteomics reveal a feedforward mechanism for mitochondrial PARKIN translocation and ubiquitin chain synthesis. | Q34622632 | ||
| Cezanne (OTUD7B) regulates HIF-1α homeostasis in a proteasome-independent manner. | Q34691368 | ||
| Linear Ubiquitin Assembly Complex Negatively Regulates RIG-I- and TRIM25-Mediated Type I Interferon Induction | Q34760296 | ||
| USP8 regulates mitophagy by removing K6-linked ubiquitin conjugates from parkin | Q34815182 | ||
| Presence of protein A24 in rat liver nucleosomes | Q35051296 | ||
| Ubiquitin acetylation inhibits polyubiquitin chain elongation | Q35084540 | ||
| Middle-down mass spectrometry enables characterization of branched ubiquitin chains | Q35212971 | ||
| K29-selective ubiquitin binding domain reveals structural basis of specificity and heterotypic nature of k29 polyubiquitin | Q35282814 | ||
| RING E3 mechanism for ubiquitin ligation to a disordered substrate visualized for human anaphase-promoting complex | Q35567086 | ||
| Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy. | Q35669194 | ||
| Substrate degradation by the proteasome: a single-molecule kinetic analysis | Q35670301 | ||
| APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1 | Q35754866 | ||
| Lys63-linked ubiquitin chain adopts multiple conformational states for specific target recognition | Q35867082 | ||
| The Proteasome Distinguishes between Heterotypic and Homotypic Lysine-11-Linked Polyubiquitin Chains | Q35943032 | ||
| The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy | Q36118105 | ||
| Efficient APC/C substrate degradation in cells undergoing mitotic exit depends on K11 ubiquitin linkages | Q36336999 | ||
| SUMO-targeted ubiquitin ligases in genome stability. | Q36439087 | ||
| A two-step mechanism for TRF2-mediated chromosome-end protection | Q37070480 | ||
| Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains | Q37191956 | ||
| Lysine 63-linked polyubiquitination is required for EGF receptor degradation | Q37203860 | ||
| K63-linked ubiquitin chains as a specific signal for protein sorting into the multivesicular body pathway | Q37237626 | ||
| The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy | Q37246125 | ||
| Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation | Q37404493 | ||
| A ubiquitin replacement strategy in human cells reveals distinct mechanisms of IKK activation by TNFalpha and IL-1beta. | Q37425442 | ||
| RNF168 promotes noncanonical K27 ubiquitination to signal DNA damage. | Q38921073 | ||
| Ubiquitin-SUMO circuitry controls activated fanconi anemia ID complex dosage in response to DNA damage | Q38923383 | ||
| Global identification of modular cullin-RING ligase substrates | Q39462405 | ||
| Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival | Q39761203 | ||
| Arsenic degrades PML or PML-RARalpha through a SUMO-triggered RNF4/ubiquitin-mediated pathway | Q39992451 | ||
| A ubiquitin mutant with specific defects in DNA repair and multiubiquitination | Q40015739 | ||
| Mixed-Linkage Ubiquitin Chains Send Mixed Messages | Q40703860 | ||
| Cell cycle-regulated modification of the ribosome by a variant multiubiquitin chain | Q40863875 | ||
| Regulated degradation of spindle assembly factors by the anaphase-promoting complex. | Q40966374 | ||
| The N-end rule pathway is mediated by a complex of the RING-type Ubr1 and HECT-type Ufd4 ubiquitin ligases | Q41199353 | ||
| Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation | Q41791638 | ||
| Efficient internalization of MHC I requires lysine-11 and lysine-63 mixed linkage polyubiquitin chains. | Q41825273 | ||
| Fluorescence-based sensors to monitor localization and functions of linear and K63-linked ubiquitin chains in cells | Q41900449 | ||
| Structural basis for the RING-catalyzed synthesis of K63-linked ubiquitin chains | Q42095239 | ||
| Mechanism of phospho-ubiquitin-induced PARKIN activation | Q42356433 | ||
| Regulation of ubiquitin chain initiation to control the timing of substrate degradation. | Q42778545 | ||
| Phosphorylation of ubiquitin at Ser65 affects its polymerization, targets, and proteome-wide turnover | Q43244956 | ||
| Definitive evidence for Ufd2-catalyzed elongation of the ubiquitin chain through Lys48 linkage | Q44968325 | ||
| Rhbdd3 controls autoimmunity by suppressing the production of IL-6 by dendritic cells via K27-linked ubiquitination of the regulator NEMO. | Q45718626 | ||
| A ubiquitin-interacting motif protects polyubiquitinated Met4 from degradation by the 26S proteasome | Q46181219 | ||
| The size of the proteasomal substrate determines whether its degradation will be mediated by mono- or polyubiquitylation | Q46223379 | ||
| Mechanism of lysine 48-linked ubiquitin-chain synthesis by the cullin-RING ubiquitin-ligase complex SCF-Cdc34. | Q46711534 | ||
| The parallel reaction monitoring method contributes to a highly sensitive polyubiquitin chain quantification | Q50946090 | ||
| The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity | Q57334872 | ||
| Novel multiubiquitin chain linkages catalyzed by the conjugating enzymes E2EPF and RAD6 are recognized by 26 S proteasome subunit 5 | Q70937723 | ||
| Identification of a novel ubiquitin-conjugating enzyme involved in mitotic cyclin degradation | Q71301624 | ||
| A series of ubiquitin binding factors connects CDC48/p97 to substrate multiubiquitylation and proteasomal targeting | Q81277350 | ||
| Ubiquitin is phosphorylated by PINK1 to activate parkin | Q24296532 | ||
| OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis | Q24297538 | ||
| Linear ubiquitination prevents inflammation and regulates immune signalling | Q24298581 | ||
| SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex | Q24298605 | ||
| SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis | Q24298626 | ||
| The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy | Q24298748 | ||
| De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling | Q24299573 | ||
| Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth | Q24304447 | ||
| A ubiquitin ligase complex assembles linear polyubiquitin chains | Q24305030 | ||
| Ubiquitin-dependent regulation of COPII coat size and function | Q24305964 | ||
| Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity | Q24307162 | ||
| The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage | Q24309181 | ||
| RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins | Q24309287 | ||
| K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC-associated Brcc36 and proteasomal Poh1 | Q24310641 | ||
| Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis | Q24310659 | ||
| Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex | Q24313604 | ||
| FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination | Q24315150 | ||
| Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation | Q24315943 | ||
| USP30 and parkin homeostatically regulate atypical ubiquitin chains on mitochondria | Q24316174 | ||
| Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains | Q24316967 | ||
| The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53 | Q24317677 | ||
| RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation | Q24320385 | ||
| The otubain YOD1 is a deubiquitinating enzyme that associates with p97 to facilitate protein dislocation from the ER | Q24323509 | ||
| UBE2S elongates ubiquitin chains on APC/C substrates to promote mitotic exit | Q24324253 | ||
| Direct activation of protein kinases by unanchored polyubiquitin chains | Q24324679 | ||
| Identification of a physiological E2 module for the human anaphase-promoting complex | Q24328862 | ||
| The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome | Q24337075 | ||
| Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase Cezanne | Q24338586 | ||
| Recognition of the polyubiquitin proteolytic signal | Q24530006 | ||
| The activity of a human endoplasmic reticulum-associated degradation E3, gp78, requires its Cue domain, RING finger, and an E2-binding site | Q24535990 | ||
| Systematic and quantitative assessment of the ubiquitin-modified proteome | Q24634631 | ||
| Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation | Q24643067 | ||
| Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathways | Q24647626 | ||
| AMSH is an endosome-associated ubiquitin isopeptidase | Q24676880 | ||
| Expanding the ubiquitin code through post-translational modification | Q26798369 | ||
| Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubc13 heterodimer | Q27633059 | ||
| Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies | Q27651780 | ||
| Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation | Q27654230 | ||
| K11-linked polyubiquitination in cell cycle control revealed by a K11 linkage-specific antibody | Q27663589 | ||
| Engineered diubiquitin synthesis reveals Lys29-isopeptide specificity of an OTU deubiquitinase | Q27664221 | ||
| An ankyrin-repeat ubiquitin-binding domain determines TRABID's specificity for atypical ubiquitin chains | Q27676107 | ||
| Engineering and Structural Characterization of a Linear Polyubiquitin-Specific Antibody | Q27676630 | ||
| Assembly, analysis and architecture of atypical ubiquitin chains | Q27677234 | ||
| Unique Structural, Dynamical, and Functional Properties of K11-Linked Polyubiquitin Chains | Q27678904 | ||
| Molecular Basis and Regulation of OTULIN-LUBAC Interaction | Q27683237 | ||
| Structure of a ubiquitin-loaded HECT ligase reveals the molecular basis for catalytic priming | Q27684556 | ||
| Binding of OTULIN to the PUB domain of HOIP controls NF-κB signaling | Q27690030 | ||
| RING domain E3 ubiquitin ligases | Q27860546 | ||
| The yeast Hex3.Slx8 heterodimer is a ubiquitin ligase stimulated by substrate sumoylation | Q27931331 | ||
| A proteolytic pathway that recognizes ubiquitin as a degradation signal | Q27932607 | ||
| Ubiquitin-dependent proteolytic control of SUMO conjugates | Q27932835 | ||
| Ubiquitin chains are remodeled at the proteasome by opposing ubiquitin ligase and deubiquitinating activities. | Q27933653 | ||
| A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly. | Q27935265 | ||
| RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. | Q27937465 | ||
| Lysine 63-linked polyubiquitin chain may serve as a targeting signal for the 26S proteasome | Q27937521 | ||
| K63 polyubiquitination is a new modulator of the oxidative stress response | Q27938946 | ||
| Protein group modification and synergy in the SUMO pathway as exemplified in DNA repair | Q27939387 | ||
| Deubiquitylase OTUD3 regulates PTEN stability and suppresses tumorigenesis | Q28117749 | ||
| TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity | Q28118562 | ||
| Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain | Q28142613 | ||
| The ubiquitin code | Q28265104 | ||
| Ubiquitin chain conformation regulates recognition and activity of interacting proteins | Q28280440 | ||
| TRAF6 is a signal transducer for interleukin-1 | Q28291934 | ||
| Ter94 ATPase Complex Targets K11-Linked Ubiquitinated Ci to Proteasomes for Partial Degradation | Q28292258 | ||
| Conformational switching of the 26S proteasome enables substrate degradation | Q28292908 | ||
| SUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damage | Q28569714 | ||
| Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells | Q28593598 | ||
| Cell-fate determination by ubiquitin-dependent regulation of translation | Q28975777 | ||
| A proteomics approach to understanding protein ubiquitination | Q29547312 | ||
| Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer | Q29547564 | ||
| A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein | Q29547884 | ||
| Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization | Q29615622 | ||
| Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL | Q29615624 | ||
| PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity | Q29617292 | ||
| Building ubiquitin chains: E2 enzymes at work | Q29619578 | ||
| Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis | Q29619757 | ||
| RNF26 temporally regulates virus-triggered type I interferon induction by two distinct mechanisms | Q29871504 | ||
| VCP is essential for mitochondrial quality control by PINK1/Parkin and this function is impaired by VCP mutations | Q30540665 | ||
| Microtubule-dependent regulation of mitotic protein degradation. | Q30572037 | ||
| Degradation signals in the lysine-asparagine sequence space | Q30804927 | ||
| UBE2S drives elongation of K11-linked ubiquitin chains by the anaphase-promoting complex | Q33575426 | ||
| Enhanced protein degradation by branched ubiquitin chains. | Q33637926 | ||
| PINK1 is degraded through the N-end rule pathway | Q33638689 | ||
| Lys11- and Lys48-linked ubiquitin chains interact with p97 during endoplasmic-reticulum-associated degradation | Q34159592 | ||
| Ubiquitin-Binding Proteins: Decoders of Ubiquitin-Mediated Cellular Functions | Q34266494 | ||
| RNF4, a SUMO-targeted ubiquitin E3 ligase, promotes DNA double-strand break repair | Q34290557 | ||
| Assembly and specific recognition of k29- and k33-linked polyubiquitin. | Q34466293 | ||
| Glutamine Deamidation and Dysfunction of Ubiquitin/NEDD8 Induced by a Bacterial Effector Family | Q34540701 | ||
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 579-586 | |
| P577 | publication date | 2016-05-01 | |
| P13046 | publication type of scholarly work | review article | Q7318358 |
| P1433 | published in | Nature Cell Biology | Q1574111 |
| P1476 | title | The increasing complexity of the ubiquitin code | |
| P478 | volume | 18 |
| Q50329951 | A Comprehensive Atlas of E3 Ubiquitin Ligase Mutations in Neurological Disorders |
| Q48676286 | A diubiquitin-based photoaffinity probe for profiling K27-linkage targeting deubiquitinases |
| Q52308769 | A fluorescence polarization-based competition assay for measuring interactions between unlabeled ubiquitin chains and UCH37•RPN13. |
| Q59326807 | A functional proteomics platform to reveal the sequence determinants of lysine methyltransferase substrate selectivity |
| Q36271570 | A high throughput mutagenic analysis of yeast sumo structure and function. |
| Q45189997 | A mobile loop near the active site acts as a switch between the dual activities of a viral protease/deubiquitinase. |
| Q92459327 | A protein quality control pathway regulated by linear ubiquitination |
| Q59327241 | A quaternary tetramer assembly inhibits the deubiquitinating activity of USP25 |
| Q48243218 | A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment. |
| Q52371879 | A versatile plasmid system for reconstitution and analysis of mammalian ubiquitination cascades in yeast |
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| Q55667374 | All roads lead to ubiquitin. |
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| Q92672295 | Artificially Linked Ubiquitin Dimers Characterised Structurally and Dynamically by NMR Spectroscopy |
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| Q90425383 | Extending chemical perturbations of the ubiquitin fitness landscape in a classroom setting reveals new constraints on sequence tolerance |
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| Q47152702 | Gammaherpesviral Tegument Proteins, PML-Nuclear Bodies and the Ubiquitin-Proteasome System |
| Q90419289 | Genome-Wide Identification, Evolution, and Expression Analysis of RING Finger Gene Family in Solanum lycopersicum |
| Q90727582 | Genome-wide CRISPR Analysis Identifies Substrate-Specific Conjugation Modules in ER-Associated Degradation |
| Q39078077 | Guard the guardian: A CRL4 ligase stands watch over histone production |
| Q57804743 | Heterozygous deletion of chromosome 17p renders prostate cancer vulnerable to inhibition of RNA polymerase II |
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| Q101166887 | High-throughput matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry-based deubiquitylating enzyme assay for drug discovery |
| Q90835355 | Histone demethylase JMJD1A promotes expression of DNA repair factors and radio-resistance of prostate cancer cells |
| Q92825683 | How the 26S Proteasome Degrades Ubiquitinated Proteins in the Cell |
| Q46552034 | How to rewire the host cell: A home improvement guide for intracellular bacteria. |
| Q60925160 | Human Platelet Protein Ubiquitylation and Changes following GPVI Activation |
| Q57285052 | Identification of Antinorovirus Genes in Human Cells Using Genome-Wide CRISPR Activation Screening. |
| Q47634102 | Identification of Proteins Interacting with Ubiquitin Chains. |
| Q53698033 | Identification of Serine 119 as an Effective Inhibitor Binding Site of M. tuberculosis Ubiquitin-like Protein Ligase PafA Using Purified Proteins and M. smegmatis |
| Q100731063 | Identification of ubiquitin Ser57 kinases regulating the oxidative stress response in yeast |
| Q92383608 | Impressionist portraits of mitotic exit: APC/C, K11-linked ubiquitin chains and Cezanne |
| Q96127623 | Insights into catalysis and regulation of non-canonical ubiquitination and deubiquitination by bacterial deamidase effectors |
| Q92625013 | Insights into ubiquitin chain architecture using Ub-clipping |
| Q91806539 | Integrative proteomics reveals an increase in non-degradative ubiquitylation in activated CD4+ T cells |
| Q47222378 | K48-linked polyubiquitination of dengue virus NS1 protein inhibits its interaction with the viral partner NS4B. |
| Q49596652 | K63 ubiquitylation triggers proteasomal degradation by seeding branched ubiquitin chains |
| Q91862920 | K63-Linked Ubiquitin Is Required for Restriction of HIV-1 Reverse Transcription and Capsid Destabilization by Rhesus TRIM5α |
| Q41560314 | KLHL41 stabilizes skeletal muscle sarcomeres by nonproteolytic ubiquitination. |
| Q60907800 | Kinetic analysis of multistep USP7 mechanism shows critical role for target protein in activity |
| Q39437877 | Legionella and Coxiella effectors: strength in diversity and activity |
| Q93054802 | Linear Ubiquitin Chains: Cellular Functions and Strategies for Detection and Quantification |
| Q104111454 | Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler |
| Q55434466 | Loss of the ubiquitin conjugating enzyme UBE2E3 induces cellular senescence. |
| Q38803414 | Manipulation of viral infection by deubiquitinating enzymes: new players in host-virus interactions |
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| Q98729346 | Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2 |
| Q47748385 | Mechanism and regulation of the Lys6-selective deubiquitinase USP30. |
| Q42321764 | Mechanism of catalysis, E2 recognition, and autoinhibition for the IpaH family of bacterial E3 ubiquitin ligases |
| Q97884884 | Mechanisms and roles of mitochondrial localisation and dynamics in neuronal function |
| Q47292178 | Meddling with Fate: The Proteasomal Deubiquitinating Enzymes |
| Q92608407 | Methods for measuring misfolded protein clearance in the budding yeast Saccharomyces cerevisiae |
| Q92233282 | Methods to analyze STUbL activity |
| Q64915831 | Mitofusins: Disease Gatekeepers and Hubs in Mitochondrial Quality Control by E3 Ligases. |
| Q89766157 | Modulation of conformational equilibrium by phosphorylation underlies the activation of deubiquitinase A |
| Q39346211 | Multiple functions of the E3 ubiquitin ligase CHIP in immunity |
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| Q83227819 | N-cadherin-regulated FGFR ubiquitination and degradation control mammalian neocortical projection neuron migration |
| Q97636083 | NORE1A directs apoptotic switch of TNF signaling through reciprocal modulation of ITCH-mediated destruction of TNFRI and BAX |
| Q90114636 | Nuclear Glycogenolysis Modulates Histone Acetylation in Human Non-Small Cell Lung Cancers |
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| Q61798624 | Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity |
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| Q47238018 | RBX1-mediated ubiquitination of SESN2 promotes cell death upon prolonged mitochondrial damage in SH-SY5Y neuroblastoma cells |
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