| scholarly article | Q13442814 |
| P356 | DOI | 10.1002/CPHY.C160024 |
| P698 | PubMed publication ID | 28640445 |
| P50 | author | Monte Willis | Q38322683 |
| P2093 | author name string | Traci L Parry | |
| David I Brown | |||
| P2860 | cites work | Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signaling | Q21144354 |
| Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions | Q22010047 | ||
| The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins | Q24290709 | ||
| F-Box and Leucine-Rich Repeat Protein 22 Is a Cardiac-Enriched F-Box Protein That Regulates Sarcomeric Protein Turnover and Is Essential for Maintenance of Contractile Function In Vivo | Q24298563 | ||
| Atrogin-1 and MuRF1 regulate cardiac MyBP-C levels via different mechanisms | Q24309993 | ||
| APS facilitates c-Cbl tyrosine phosphorylation and GLUT4 translocation in response to insulin in 3T3-L1 adipocytes | Q24537413 | ||
| Sorting out the roles of PPAR alpha in energy metabolism and vascular homeostasis | Q24541529 | ||
| Muscle-specific RING finger 1 is a bona fide ubiquitin ligase that degrades cardiac troponin I | Q24558612 | ||
| Isolation of a polypeptide that has lymphocyte-differentiating properties and is probably represented universally in living cells | Q24564684 | ||
| Resolution of the ATP-dependent proteolytic system from reticulocytes: a component that interacts with ATP | Q24596392 | ||
| A soluble ATP-dependent proteolytic system responsible for the degradation of abnormal proteins in reticulocytes | Q24602678 | ||
| The AMPK signalling pathway coordinates cell growth, autophagy and metabolism | Q24616273 | ||
| Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes | Q24645701 | ||
| Myosin accumulation and striated muscle myopathy result from the loss of muscle RING finger 1 and 3 | Q24673171 | ||
| Thyroid hormone-mediated autophagy and mitochondrial turnover in NAFLD | Q26738872 | ||
| Linking F-box protein 7 and parkin to neuronal degeneration in Parkinson's disease (PD) | Q26752685 | ||
| CHIP deficiency decreases longevity, with accelerated aging phenotypes accompanied by altered protein quality control | Q36710789 | ||
| Diabetic cardiomyopathy revisited | Q36860318 | ||
| Activation of mTORC1 is essential for β-adrenergic stimulation of adipose browning. | Q36867350 | ||
| Parkin overexpression during aging reduces proteotoxicity, alters mitochondrial dynamics, and extends lifespan | Q36884177 | ||
| Muscle RING-finger 2 and 3 maintain striated-muscle structure and function | Q36892025 | ||
| Diminished autophagy limits cardiac injury in mouse models of type 1 diabetes | Q36947750 | ||
| The Adaptor-Related Protein Complex 2, Alpha 2 Subunit (AP2α2) Gene is a Peroxisome Proliferator-Activated Receptor Cardiac Target Gene | Q36975430 | ||
| CHIP protects against cardiac pressure overload through regulation of AMPK | Q37052961 | ||
| Muscle ring finger 1 and muscle ring finger 2 are necessary but functionally redundant during developmental cardiac growth and regulate E2F1-mediated gene expression in vivo | Q37057089 | ||
| Distinct dysregulation of lipid metabolism by unliganded thyroid hormone receptor isoforms | Q37125466 | ||
| Protein kinase g positively regulates proteasome-mediated degradation of misfolded proteins. | Q37142904 | ||
| Glucocorticoids and fatty acid metabolism in humans: fuelling fat redistribution in the metabolic syndrome | Q37146918 | ||
| Carboxyl terminus of Hsp70-interacting protein (CHIP) is required to modulate cardiac hypertrophy and attenuate autophagy during exercise. | Q37164690 | ||
| FoxO1 deacetylation regulates thyroid hormone-induced transcription of key hepatic gluconeogenic genes | Q37234039 | ||
| During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation | Q37264046 | ||
| Beyond ubiquitination: the atypical functions of Fbxo7 and other F-box proteins. | Q37272000 | ||
| The role of autophagy in the heart. | Q37325466 | ||
| Targeting Hsp90/Hsp70-based protein quality control for treatment of adult onset neurodegenerative diseases | Q26859909 | ||
| New avenues for regulation of lipid metabolism by thyroid hormones and analogs | Q27003043 | ||
| Tumor suppressor p53 and its mutants in cancer metabolism | Q27010683 | ||
| Targeting the ubiquitin-proteasome system in heart disease: the basis for new therapeutic strategies | Q27026951 | ||
| Targeted inhibition of the deubiquitinating enzymes, USP14 and UCHL5, induces proteotoxic stress and apoptosis in Waldenström macroglobulinaemia tumour cells | Q27314737 | ||
| FBXO32, encoding a member of the SCF complex, is mutated in dilated cardiomyopathy | Q28116320 | ||
| Regulation of Abro1/KIAA0157 during myocardial infarction and cell death reveals a novel cardioprotective mechanism for Lys63-specific deubiquitination | Q28116438 | ||
| Thyroid hormone induction of mitochondrial activity is coupled to mitophagy via ROS-AMPK-ULK1 signaling | Q28118597 | ||
| Hyperubiquitination of proteins in dilated cardiomyopathy | Q28211649 | ||
| Regulation of murine cardiac 20S proteasomes: role of associating partners | Q28253191 | ||
| MURF-1 and MURF-2 target a specific subset of myofibrillar proteins redundantly: towards understanding MURF-dependent muscle ubiquitination | Q28257682 | ||
| Ubiquitin proteasome dysfunction in human hypertrophic and dilated cardiomyopathies | Q28273319 | ||
| The Cbl interactome and its functions | Q28277251 | ||
| Parkin is protective against proteotoxic stress in a transgenic zebrafish model | Q28474988 | ||
| Proteotoxic stress increases nuclear localization of ataxin-3 | Q28506165 | ||
| MEKK1 mediates the ubiquitination and degradation of c-Jun in response to osmotic stress | Q28566574 | ||
| Differential 3,5,3'-triiodothyronine-mediated regulation of uncoupling protein 3 transcription: role of Fatty acids | Q28578748 | ||
| Role of Sirtuin 1 in the Regulation of Hepatic Gene Expression by Thyroid Hormone | Q28579828 | ||
| c-Cbl Ubiquitin Ligase Regulates Focal Adhesion Protein Turnover and Myofibril Degeneration Induced by Neutrophil Protease Cathepsin G | Q28581185 | ||
| Identification of Ubiquitin Ligases Required for Skeletal Muscle Atrophy | Q28582211 | ||
| Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53 | Q29614430 | ||
| Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53 | Q29617850 | ||
| The failing heart--an engine out of fuel | Q29617881 | ||
| RBX1 (RING box protein 1) E3 ubiquitin ligase is required for genomic integrity by modulating DNA replication licensing proteins | Q30498021 | ||
| Cloning and characterization of two novel thyroid hormone receptor beta isoforms | Q33605367 | ||
| Expression of uncoupling protein 1 in mouse brown adipose tissue is thyroid hormone receptor-beta isoform specific and required for adaptive thermogenesis | Q33634049 | ||
| Muscle-specific RING finger 1 negatively regulates pathological cardiac hypertrophy through downregulation of calcineurin A. | Q33651036 | ||
| MAFbx/Atrogin-1 is required for atrophic remodeling of the unloaded heart. | Q33680276 | ||
| Atrogin-1 deficiency promotes cardiomyopathy and premature death via impaired autophagy | Q33685877 | ||
| Thyroid hormone regulation of metabolism | Q33707954 | ||
| c-Cbl inhibition improves cardiac function and survival in response to myocardial ischemia | Q33710767 | ||
| MuRF1 activity is present in cardiac mitochondria and regulates reactive oxygen species production in vivo | Q33717313 | ||
| MuRF1 mono-ubiquitinates TRα to inhibit T3-induced cardiac hypertrophy in vivo. | Q33752237 | ||
| MuRF1 is a muscle fiber-type II associated factor and together with MuRF2 regulates type-II fiber trophicity and maintenance. | Q33798765 | ||
| SCF increases cardiac stem cell migration through PI3K/AKT and MMP‑2/‑9 signaling | Q33811230 | ||
| MuRF2 regulates PPARγ1 activity to protect against diabetic cardiomyopathy and enhance weight gain induced by a high fat diet | Q35920226 | ||
| Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins | Q36088932 | ||
| Myocardial substrate metabolism in the normal and failing heart | Q36179008 | ||
| Non-targeted metabolomics analysis of cardiac Muscle Ring Finger-1 (MuRF1), MuRF2, and MuRF3 in vivo reveals novel and redundant metabolic changes. | Q36317111 | ||
| The histone deacetylase inhibitor butyrate improves metabolism and reduces muscle atrophy during aging | Q36410021 | ||
| Receptor tyrosine kinase ErbB2 translocates into mitochondria and regulates cellular metabolism | Q36464712 | ||
| Parkin protein deficiency exacerbates cardiac injury and reduces survival following myocardial infarction | Q36526385 | ||
| MDM2 E3 ligase-mediated ubiquitination and degradation of HDAC1 in vascular calcification | Q36541232 | ||
| Parkin-mediated mitophagy directs perinatal cardiac metabolic maturation in mice | Q36561435 | ||
| SCF(Fbxo22)-KDM4A targets methylated p53 for degradation and regulates senescence. | Q36582281 | ||
| The Failing Heart Relies on Ketone Bodies as a Fuel | Q36614537 | ||
| Evidence for Intramyocardial Disruption of Lipid Metabolism and Increased Myocardial Ketone Utilization in Advanced Human Heart Failure. | Q36654675 | ||
| Emerging evidence of coding mutations in the ubiquitin-proteasome system associated with cerebellar ataxias | Q36671121 | ||
| Cardiac muscle ring finger-1 increases susceptibility to heart failure in vivo | Q37332162 | ||
| Altered ubiquitin-proteasome signaling in right ventricular hypertrophy and failure | Q37476517 | ||
| Muscle RING finger-1 attenuates IGF-I-dependent cardiomyocyte hypertrophy by inhibiting JNK signaling | Q37655989 | ||
| Cross-functional E3 ligases Parkin and C-terminus Hsp70-interacting protein in neurodegenerative disorders. | Q37958101 | ||
| AMPK regulation of fatty acid metabolism and mitochondrial biogenesis: implications for obesity. | Q38023047 | ||
| Proteotoxicity and cardiac dysfunction--Alzheimer's disease of the heart? | Q38077849 | ||
| Emerging roles of E3 ubiquitin ligases in autophagy | Q38122815 | ||
| The role of ubiquitin ligases in cardiac disease. | Q38164901 | ||
| Glucose and glutamine metabolism control by APC and SCF during the G1-to-S phase transition of the cell cycle. | Q38194070 | ||
| Genetic ablation of the c-Cbl ubiquitin ligase domain results in increased energy expenditure and improved insulin action | Q38307291 | ||
| How mitochondrial dynamism orchestrates mitophagy | Q38497008 | ||
| AMPK: energy sensor and survival mechanism in the ischemic heart | Q38544724 | ||
| Nongenomic actions of thyroid hormone. | Q38669510 | ||
| The increasing complexity of the ubiquitin code | Q38845500 | ||
| Cardiac ubiquitin ligases: Their role in cardiac metabolism, autophagy, cardioprotection and therapeutic potential | Q38898242 | ||
| Silencing of PINK1 inhibits insulin-like growth factor-1-mediated receptor activation and neuronal survival. | Q38926013 | ||
| AMP-activated protein kinase regulates thyroid hormone-stimulated osteocalcin synthesis in osteoblasts. | Q39166029 | ||
| Structure and recognition of polyubiquitin chains of different lengths and linkage | Q39553217 | ||
| Regulation of glycogen synthesis by the laforin-malin complex is modulated by the AMP-activated protein kinase pathway | Q40047094 | ||
| The E3 Ligase MuRF1 degrades myosin heavy chain protein in dexamethasone-treated skeletal muscle | Q40056196 | ||
| Thyroid hormone receptor TRbeta1 mediates Akt activation by T3 in pancreatic beta cells. | Q40172304 | ||
| Atrogin-1/muscle atrophy F-box inhibits calcineurin-dependent cardiac hypertrophy by participating in an SCF ubiquitin ligase complex | Q40177208 | ||
| Differential regulation of cardiomyocyte survival and hypertrophy by MDM2, an E3 ubiquitin ligase | Q40341746 | ||
| Endogenous muscle atrophy F-box mediates pressure overload-induced cardiac hypertrophy through regulation of nuclear factor-kappaB. | Q40367733 | ||
| A central thermogenic-like mechanism in feeding regulation: an interplay between arcuate nucleus T3 and UCP2. | Q41773950 | ||
| E3 ubiquitin ligase CHIP and NBR1-mediated selective autophagy protect additively against proteotoxicity in plant stress responses. | Q41900992 | ||
| Macrophage migration inhibitory factor deletion exacerbates pressure overload-induced cardiac hypertrophy through mitigating autophagy | Q41967343 | ||
| Genetically induced moderate inhibition of 20S proteasomes in cardiomyocytes facilitates heart failure in mice during systolic overload | Q42428235 | ||
| Cardiomyocyte degeneration with calpain deficiency reveals a critical role in protein homeostasis | Q42509054 | ||
| Altered regulation of the PINK1 locus: a link between type 2 diabetes and neurodegeneration? | Q42514046 | ||
| Laforin and malin knockout mice have normal glucose disposal and insulin sensitivity | Q42590742 | ||
| Muscle ring finger 1, but not muscle ring finger 2, regulates cardiac hypertrophy in vivo | Q42750583 | ||
| Parkin Protects Against Misfolded SOD1 Toxicity by Promoting Its Aggresome Formation and Autophagic Clearance | Q42788514 | ||
| Hot stuff: thyroid hormones and AMPK | Q42829352 | ||
| Ubiquitination and degradation of the anti-apoptotic protein ARC by MDM2. | Q42833116 | ||
| The T3 receptor beta1 isoform regulates UCP1 and D2 deiodinase in rat brown adipocytes. | Q42933719 | ||
| Requirement for thyroid hormone receptor beta in T3 regulation of cholesterol metabolism in mice | Q44081203 | ||
| Parkin protects against the toxicity associated with mutant alpha-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons | Q44258606 | ||
| Myocytes die by multiple mechanisms in failing human hearts | Q44370216 | ||
| Control of cardiac pyruvate dehydrogenase activity in peroxisome proliferator-activated receptor-alpha transgenic mice | Q44381078 | ||
| Thyroid hormone induces rapid activation of Akt/protein kinase B-mammalian target of rapamycin-p70S6K cascade through phosphatidylinositol 3-kinase in human fibroblasts | Q45075628 | ||
| Deubiquitinating enzyme CYLD mediates pressure overload-induced cardiac maladaptive remodeling and dysfunction via downregulating Nrf2. | Q46734603 | ||
| A structural role for hormone in the thyroid hormone receptor. | Q46828407 | ||
| Activation of the Cbl insulin signaling pathway in cardiac muscle; dysregulation in obesity and diabetes | Q46957755 | ||
| Casitas b-lineage lymphoma-deficient mice are protected against high-fat diet-induced obesity and insulin resistance | Q46966521 | ||
| Proteasome inhibition attenuates infarct size and preserves cardiac function in a murine model of myocardial ischemia-reperfusion injury. | Q47282390 | ||
| New cardiac and skeletal protein aggregate myopathy associated with combined MuRF1 and MuRF3 mutations | Q50449574 | ||
| AMPK signaling pathway is rapidly activated by T3 and regulates the cardiomyocyte growth. | Q50925502 | ||
| CHIP, a cochaperone/ubiquitin ligase that regulates protein quality control, is required for maximal cardioprotection after myocardial infarction in mice | Q51594198 | ||
| Atrogin-1 Pathway Activation in Cushing Syndrome Cardiomyopathy | Q53210302 | ||
| Ubiquitin-Specific Protease 4 Is an Endogenous Negative Regulator of Pathological Cardiac Hypertrophy | Q54202320 | ||
| Atrogin-1/MAFbx enhances simulated ischemia/reperfusion-induced apoptosis in cardiomyocytes through degradation of MAPK phosphatase-1 and sustained JNK activation | Q54501477 | ||
| The generation of the oxidized form of creatine kinase is a negative regulation on muscle creatine kinase. | Q55043242 | ||
| In vitro binding of triiodothyronine to rat liver mitochondria | Q70664003 | ||
| Rapid effect of triiodothyronine on the mitochondrial pathway in rat liver in vivo | Q71342510 | ||
| Insulin-induced up-regulated uncoupling protein-1 expression is mediated by insulin receptor substrate 1 through the phosphatidylinositol 3-kinase/Akt signaling pathway in fetal brown adipocytes | Q78785297 | ||
| Activation of the cardiac proteasome during pressure overload promotes ventricular hypertrophy | Q79249946 | ||
| A mutant thyroid hormone receptor alpha antagonizes peroxisome proliferator-activated receptor alpha signaling in vivo and impairs fatty acid oxidation | Q79377642 | ||
| The dominant negative thyroid hormone receptor beta-mutant {Delta}337T alters PPAR{alpha} signaling in heart | Q80294390 | ||
| Elevated p53 expression is associated with dysregulation of the ubiquitin-proteasome system in dilated cardiomyopathy | Q80979295 | ||
| Marked differences between atrial and ventricular gene-expression remodeling in dogs with experimental heart failure | Q82014544 | ||
| Depression of proteasome activities during the progression of cardiac dysfunction in pressure-overloaded heart of mice | Q82222281 | ||
| Identification of atrogin-1-targeted proteins during the myostatin-induced skeletal muscle wasting | Q84310829 | ||
| High-resolution separation of cardiovascular proteomes: two-dimensional electrophoresis and liquid chromatography | Q85209048 | ||
| p28, a truncated form of TRα1 regulates mitochondrial physiology | Q85646844 | ||
| Protein degradation and quality control in cells from laforin and malin knockout mice | Q33947038 | ||
| A variant form of the nuclear triiodothyronine receptor c-ErbAalpha1 plays a direct role in regulation of mitochondrial RNA synthesis | Q33960511 | ||
| The laforin-malin complex, involved in Lafora disease, promotes the incorporation of K63-linked ubiquitin chains into AMP-activated protein kinase beta subunits. | Q34029315 | ||
| Genetic depletion of the malin E3 ubiquitin ligase in mice leads to lafora bodies and the accumulation of insoluble laforin | Q34055790 | ||
| A heat-stable polypeptide component of an ATP-dependent proteolytic system from reticulocytes | Q34056133 | ||
| Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance | Q34112635 | ||
| Germline CBL mutations cause developmental abnormalities and predispose to juvenile myelomonocytic leukemia | Q34130332 | ||
| Thyroid hormone action in mitochondria | Q34138873 | ||
| Tissue-specific differences of p53 inhibition by Mdm2 and Mdm4. | Q34233412 | ||
| Minireview: hey U(PS): metabolic and proteolytic homeostasis linked via AMPK and the ubiquitin proteasome system | Q34265028 | ||
| The kinase domain of titin controls muscle gene expression and protein turnover | Q34407820 | ||
| Transcriptional Effects of E3 Ligase Atrogin-1/MAFbx on Apoptosis, Hypertrophy and Inflammation in Neonatal Rat Cardiomyocytes | Q34555764 | ||
| Muscle ring finger 1 mediates cardiac atrophy in vivo | Q34603561 | ||
| T₃-induced liver AMP-activated protein kinase signaling: redox dependency and upregulation of downstream targets | Q34696633 | ||
| Muscle RING-finger protein-1 (MuRF1) as a connector of muscle energy metabolism and protein synthesis | Q34742154 | ||
| The ubiquitin ligase MuRF1 protects against cardiac ischemia/reperfusion injury by its proteasome-dependent degradation of phospho-c-Jun. | Q34760678 | ||
| Versatile roles of k63-linked ubiquitin chains in trafficking | Q34774715 | ||
| Thyroid hormone mediated changes in gene expression can be initiated by cytosolic action of the thyroid hormone receptor beta through the phosphatidylinositol 3-kinase pathway | Q34803411 | ||
| SIRT1 is a Direct Coactivator of Thyroid Hormone Receptor β1 with Gene-Specific Actions | Q34905848 | ||
| Peroxisome proliferator-activated receptor alpha (PPARalpha) signaling in the gene regulatory control of energy metabolism in the normal and diseased heart | Q34993589 | ||
| Thyroid hormone binding by a component of mitochondrial membrane | Q35086661 | ||
| Enhancement of proteasomal function protects against cardiac proteinopathy and ischemia/reperfusion injury in mice | Q35187068 | ||
| New insights into insulin resistance in the diabetic heart | Q35243945 | ||
| Phosphatase and tensin homolog-induced putative kinase 1 and Parkin in diabetic heart: Role of mitophagy | Q35571792 | ||
| PINK1 enhances insulin-like growth factor-1-dependent Akt signaling and protection against apoptosis. | Q35577571 | ||
| Metabolic remodelling of the failing heart: the cardiac burn-out syndrome? | Q35635100 | ||
| AMP-Activated Protein Kinase Regulates E3 Ligases in Rodent Heart | Q35661532 | ||
| Parkin loss of function contributes to RTP801 elevation and neurodegeneration in Parkinson's disease. | Q35679526 | ||
| PINK1-Parkin-Mediated Mitophagy Protects Mitochondrial Integrity and Prevents Metabolic Stress-Induced Endothelial Injury | Q35687671 | ||
| Muscle ring finger-3 protects against diabetic cardiomyopathy induced by a high fat diet. | Q35716907 | ||
| Back to your heart: ubiquitin proteasome system-regulated signal transduction | Q35803035 | ||
| Interdependence of Parkin-Mediated Mitophagy and Mitochondrial Fission in Adult Mouse Hearts | Q35908527 | ||
| The ubiquitin ligase MuRF1 regulates PPARα activity in the heart by enhancing nuclear export via monoubiquitination | Q35911960 | ||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 841-862 | |
| P577 | publication date | 2017-06-18 | |
| P13046 | publication type of scholarly work | review article | Q7318358 |
| P1433 | published in | Comprehensive Physiology | Q15716484 |
| P1476 | title | Ubiquitin Ligases and Posttranslational Regulation of Energy in the Heart: The Hand that Feeds | |
| P478 | volume | 7 |
| Q58728912 | Emergence of Members of TRAF and DUB of Ubiquitin Proteasome System in the Regulation of Hypertrophic Cardiomyopathy |
| Q99568710 | Preoperative myocardial expression of E3 ubiquitin ligases in aortic stenosis patients undergoing valve replacement and their association to postoperative hypertrophy |
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