| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2016NatCo...710574J |
| P356 | DOI | 10.1038/NCOMMS10574 |
| P932 | PMC publication ID | 4754341 |
| P698 | PubMed publication ID | 26868148 |
| P5875 | ResearchGate publication ID | 294288856 |
| P50 | author | Aya Naiki-Ito | Q80139775 |
| Hiroyuki Aburatani | Q87657008 | ||
| Masatoshi Kitagawa | Q114390223 | ||
| Kyoko Kitagawa | Q114390236 | ||
| P2093 | author name string | Makoto Nakanishi | |
| Satoru Takahashi | |||
| Keiko Nakanishi | |||
| Jia Sun | |||
| Ichiro Miyoshi | |||
| Tomomi Miyamoto | |||
| Toshiya Kuno | |||
| Atsushi Okabe | |||
| Yoshikazu Johmura | |||
| Yumi Sawada | |||
| ShengFan Li | |||
| P2860 | cites work | Transient activation of p53 in G2 phase is sufficient to induce senescence. | Q53043642 |
| Aging. When do telomeres matter? | Q73557244 | ||
| Signaling to p53: breaking the MDM2-p53 circuit | Q77430977 | ||
| Regulation of p53 activity through lysine methylation | Q24311514 | ||
| Acetylation is indispensable for p53 activation | Q24313477 | ||
| A biomarker that identifies senescent human cells in culture and in aging skin in vivo | Q24562644 | ||
| PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53 | Q24594648 | ||
| Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain | Q27860534 | ||
| Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication | Q28209282 | ||
| Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication | Q28507216 | ||
| One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering | Q29547524 | ||
| Cellular senescence: when bad things happen to good cells | Q29615561 | ||
| Switching and signaling at the telomere | Q29615653 | ||
| p53 induces distinct epigenetic states at its direct target promoters | Q33376888 | ||
| Mechanisms of switching on p53: a role for covalent modification? | Q33807813 | ||
| Four faces of cellular senescence. | Q34025754 | ||
| Cellular senescence and the senescent secretory phenotype: therapeutic opportunities | Q34035882 | ||
| The impact of acetylation and deacetylation on the p53 pathway | Q34199692 | ||
| The essence of senescence | Q34288983 | ||
| JMJD2A promotes cellular transformation by blocking cellular senescence through transcriptional repression of the tumor suppressor CHD5. | Q34312855 | ||
| Exit from G0 and entry into the cell cycle of cells expressing p21Sdi1 antisense RNA. | Q34324961 | ||
| Limiting the power of p53 through the ubiquitin proteasome pathway | Q34342940 | ||
| An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA | Q34453396 | ||
| p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype | Q35007977 | ||
| Control of the senescence-associated secretory phenotype by NF-κB promotes senescence and enhances chemosensitivity | Q35493953 | ||
| Reversal of human cellular senescence: roles of the p53 and p16 pathways | Q35561999 | ||
| It Takes 15 to Tango: Making Sense of the Many Ubiquitin Ligases of p53. | Q36387588 | ||
| The Regulation of Multiple p53 Stress Responses is Mediated through MDM2 | Q36387610 | ||
| Lysine methylation goes global | Q36499918 | ||
| The p53-Mdm2 feedback loop protects against DNA damage by inhibiting p53 activity but is dispensable for p53 stability, development, and longevity | Q37185622 | ||
| The peroxisome proliferator-activated receptor gamma/retinoid X receptor alpha heterodimer targets the histone modification enzyme PR-Set7/Setd8 gene and regulates adipogenesis through a positive feedback loop | Q37233465 | ||
| p53 regulation by ubiquitin | Q37882073 | ||
| The role of ubiquitin modification in the regulation of p53. | Q38112497 | ||
| MDM2's social network | Q38149734 | ||
| Lysine-specific modifications of p53: a matter of life and death? | Q38168223 | ||
| SCF(FBXO22) regulates histone H3 lysine 9 and 36 methylation levels by targeting histone demethylase KDM4A for ubiquitin-mediated proteasomal degradation. | Q38285971 | ||
| Multiple C-terminal lysine residues target p53 for ubiquitin-proteasome-mediated degradation | Q39540070 | ||
| Regulation of GATA-binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of THR176 in GATA-binding protein 2. | Q39715869 | ||
| Methylation-acetylation interplay activates p53 in response to DNA damage | Q40103473 | ||
| Replicative senescence: implications for in vivo aging and tumor suppression | Q41003046 | ||
| Targeting of substrates to the 26S proteasome | Q41641565 | ||
| Necessary and sufficient role for a mitosis skip in senescence induction | Q48725702 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 10574 | |
| P577 | publication date | 2016-02-12 | |
| P1433 | published in | Nature Communications | Q573880 |
| P1476 | title | SCF(Fbxo22)-KDM4A targets methylated p53 for degradation and regulates senescence | |
| P478 | volume | 7 |
| Q64946045 | Application of ex-vivo spheroid model system for the analysis of senescence and senolytic phenotypes in uterine leiomyoma. |
| Q39179169 | Beyond histones - the expanding roles of protein lysine methylation |
| Q38988645 | Brief Report: Proteasomal Indoleamine 2,3-Dioxygenase Degradation Reduces the Immunosuppressive Potential of Clinical Grade-Mesenchymal Stromal Cells Undergoing Replicative Senescence. |
| Q41527633 | Detection of the Ubiquitinome in Cells Undergoing Oncogene-Induced Senescence |
| Q64104228 | Emerging role of F-box proteins in the regulation of epithelial-mesenchymal transition and stem cells in human cancers |
| Q98465923 | Emerging role of FBXO22 in carcinogenesis |
| Q37631700 | F-Box Protein FBXO22 Mediates Polyubiquitination and Degradation of CD147 to Reverse Cisplatin Resistance of Tumor Cells |
| Q61810405 | FBXO22 Suppresses Metastasis in Human Renal Cell Carcinoma via Inhibiting MMP-9-Mediated Migration and Invasion and VEGF-Mediated Angiogenesis |
| Q91583393 | FBXO22 degrades nuclear PTEN to promote tumorigenesis |
| Q64921368 | FBXO22 mediates polyubiquitination and inactivation of LKB1 to promote lung cancer cell growth. |
| Q64101710 | FBXO22 promotes the development of hepatocellular carcinoma by regulating the ubiquitination and degradation of p21 |
| Q64882055 | Fbxo22-mediated KDM4B degradation determines selective estrogen receptor modulator activity in breast cancer. |
| Q90291325 | Genome-wide Kdm4 histone demethylase transcriptional regulation in Drosophila |
| Q47304462 | Health benefits of late-onset metformin treatment every other week in mice |
| Q64254974 | Histone demethylase KDM3A is required for enhancer activation of hippo target genes in colorectal cancer |
| Q89739763 | Inhibition of USP7 activity selectively eliminates senescent cells in part via restoration of p53 activity |
| Q57280070 | Isozyme-Specific Role of SAD-A in Neuronal Migration During Development of Cerebral Cortex |
| Q61799432 | Jumonji C Demethylases in Cellular Senescence |
| Q90571091 | MICAL2 Mediates p53 Ubiquitin Degradation through Oxidating p53 Methionine 40 and 160 and Promotes Colorectal Cancer Malignance |
| Q59326864 | MNAT1 is overexpressed in colorectal cancer and mediates p53 ubiquitin-degradation to promote colorectal cancer malignance |
| Q39358659 | MicroRNA Regulation of Oxidative Stress-Induced Cellular Senescence |
| Q26738906 | Multiple facets of p53 in senescence induction and maintenance |
| Q98944902 | RFX5 promotes the progression of hepatocellular carcinoma through transcriptional activation of KDM4A |
| Q92355364 | SCFFBXO22 targets HDM2 for degradation and modulates breast cancer cell invasion and metastasis |
| Q55709240 | Small molecule KDM4s inhibitors as anti-cancer agents. |
| Q64228390 | Sugar-Recognizing Ubiquitin Ligases: Action Mechanisms and Physiology |
| Q42380380 | The Immortal Senescence |
| Q41116146 | The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway |
| Q39390991 | Ubiquitin Ligases and Posttranslational Regulation of Energy in the Heart: The Hand that Feeds |
| Q91701515 | p53 modifications: exquisite decorations of the powerful guardian |
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