Beyond histones - the expanding roles of protein lysine methylation

scientific article published on 9 March 2017

Beyond histones - the expanding roles of protein lysine methylation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/FEBS.14056
P698PubMed publication ID28294537

P2093author name stringKyle K Biggar
Zhouran Wu
Justin Connolly
P2860cites workIdentification of arginine- and lysine-methylation in the proteome of Saccharomyces cerevisiae and its functional implicationsQ21267196
Genome-wide survey and developmental expression mapping of zebrafish SET domain-containing genesQ21562301
p53 is regulated by the lysine demethylase LSD1Q24292925
Phosphorylation of EZH2 activates STAT3 signaling via STAT3 methylation and promotes tumorigenicity of glioblastoma stem-like cellsQ24293124
G9a and Glp methylate lysine 373 in the tumor suppressor p53Q24298004
Methylation of the retinoblastoma tumor suppressor by SMYD2Q24300912
L3MBTL1, a histone-methylation-dependent chromatin lockQ24307503
Interplay between lysine methylation and Cdk phosphorylation in growth control by the retinoblastoma proteinQ24310370
Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signalingQ24312041
Identification and characterization of a novel human methyltransferase modulating Hsp70 protein function through lysine methylationQ24315705
Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylationQ36381487
Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemiaQ36515569
SCF(Fbxo22)-KDM4A targets methylated p53 for degradation and regulates senescence.Q36582281
Role for 53BP1 Tudor domain recognition of p53 dimethylated at lysine 382 in DNA damage signalingQ37000240
Large-scale global identification of protein lysine methylation in vivoQ37089501
Regulation of estrogen receptor α by histone methyltransferase SMYD2-mediated protein methylationQ37256023
Global proteomic analysis in trypanosomes reveals unique proteins and conserved cellular processes impacted by arginine methylationQ37605010
Lysine methylation: beyond histonesQ37970950
Push back to respond better: regulatory inhibition of the DNA double-strand break responseQ38133962
An H3K9/S10 methyl-phospho switch modulates Polycomb and Pol II binding at repressed genes during differentiationQ38266057
Non-histone protein methylation as a regulator of cellular signalling and functionQ38285792
Critical roles of non-histone protein lysine methylation in human tumorigenesisQ38329400
Identification and characterization of lysine-methylated sites on histones and non-histone proteinsQ38479488
Emerging roles of lysine methylation on non-histone proteinsQ38557842
Protein lysine methylation by seven-β-strand methyltransferasesQ38894639
Selective inhibition of EZH2 by EPZ-6438 leads to potent antitumor activity in EZH2-mutant non-Hodgkin lymphomaQ39021479
Dynamic methylation of Numb by Set8 regulates its binding to p53 and apoptosisQ39147711
Regulation of the androgen receptor by SET9-mediated methylationQ39642231
Methylation of p53 by Set7/9 mediates p53 acetylation and activity in vivoQ40012428
The lysine 831 of vascular endothelial growth factor receptor 1 is a novel target of methylation by SMYD3.Q40050639
Concerted activities of distinct H4K20 methyltransferases at DNA double-strand breaks regulate 53BP1 nucleation and NHEJ-directed repairQ42793535
A proteomic analysis of arginine-methylated protein complexesQ44611061
The cation-π interaction at protein-protein interaction interfaces: developing and learning from synthetic mimics of proteins that bind methylated lysinesQ45777054
Control of the hippo pathway by Set7-dependent methylation of Yap.Q46240754
Characterization of articular cartilage and subchondral bone changes in the rat anterior cruciate ligament transection and meniscectomized models of osteoarthritisQ46722069
p53-dependent transcription and tumor suppression are not affected in Set7/9-deficient mice.Q53224748
Specificity Analysis-Based Identification of New Methylation Targets of the SET7/9 Protein Lysine MethyltransferaseQ57267611
ɛ-N-Methyl-lysine in Bacterial Flagellar ProteinQ59051870
Repression of p53 activity by Smyd2-mediated methylationQ24315991
Histone demethylation mediated by the nuclear amine oxidase homolog LSD1Q24336747
Modulation of p53 function by SET8-mediated methylation at lysine 382Q24337822
PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53Q24594648
Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repairQ24669691
Integration with the human genome of peptide sequences obtained by high-throughput mass spectrometryQ24805791
Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD FingerQ27649150
Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294Q27653816
The MBT Repeats of L3MBTL1 Link SET8-mediated p53 Methylation at Lysine 382 to Target Gene RepressionQ27664677
Structural basis of substrate methylation and inhibition of SMYD2Q27670959
Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domainQ27860477
Regulation of histone methylation by demethylimination and demethylationQ28291841
The Tudor domain 'Royal Family': Tudor, plant Agenet, Chromo, PWWP and MBT domainsQ29614228
The diverse functions of histone lysine methylationQ29614523
Regulation of HP1-chromatin binding by histone H3 methylation and phosphorylationQ29614524
Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damageQ29614528
EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutationsQ29615392
Histone methylation in transcriptional controlQ29616553
Epigenetic protein families: a new frontier for drug discoveryQ29616621
VEGF receptor signalling - in control of vascular functionQ29617256
trans-2-Phenylcyclopropylamine is a mechanism-based inactivator of the histone demethylase LSD1.Q33279148
A method for systematic mapping of protein lysine methylation identifies functions for HP1β in DNA damage responseQ33656610
The nuclear factor NF-kappaB pathway in inflammationQ34114512
EZH2 generates a methyl degron that is recognized by the DCAF1/DDB1/CUL4 E3 ubiquitin ligase complexQ34305930
SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancerQ34420873
Regulation of p53 function by lysine methylationQ35149921
Discovery of substrates for a SET domain lysine methyltransferase predicted by multistate computational protein design.Q35532661
Histone lysine methylation: a signature for chromatin functionQ35571556
A Proteomic Strategy Identifies Lysine Methylation of Splicing Factor snRNP70 by the SETMAR EnzymeQ35583081
Novel histone demethylase LSD1 inhibitors selectively target cancer cells with pluripotent stem cell propertiesQ35587244
Bioorthogonal profiling of protein methylation using azido derivative of S-adenosyl-L-methionineQ35912065
RB1 methylation by SMYD2 enhances cell cycle progression through an increase of RB1 phosphorylationQ36088167
Involvement of E2F transcription factor family in cancerQ36280634
Proteome-wide enrichment of proteins modified by lysine methylation.Q36294652
P407language of work or nameEnglishQ1860
P577publication date2017-03-09
P1433published inFEBS JournalQ1388041
P1476titleBeyond histones - the expanding roles of protein lysine methylation

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cites work (P2860)
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Q90477254Intriguing Origins of Protein Lysine Methylation: Influencing Cell Function Through Dynamic Methylation
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Q47328337Proteins and Proteoforms: New Separation Challenges.
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Q55511922The ribosome: A hot spot for the identification of new types of protein methyltransferases.

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