Muscle RING finger-1 attenuates IGF-I-dependent cardiomyocyte hypertrophy by inhibiting JNK signaling

scientific article published on 14 January 2014

Muscle RING finger-1 attenuates IGF-I-dependent cardiomyocyte hypertrophy by inhibiting JNK signaling is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1152/AJPENDO.00326.2013
P932PMC publication ID3962608
P698PubMed publication ID24425758
P5875ResearchGate publication ID259725693

P50authorMonte WillisQ38322683
Kristine M WadoskyQ63853890
P2093author name stringJessica E Rodríguez
Bethany L Walton
Jin-na Min
Rebecca L Hite
P2860cites workMuscle-specific RING finger-1 interacts with titin to regulate sarcomeric M-line and thick filament structure and may have nuclear functions via its interaction with glucocorticoid modulatory element binding protein-1Q24293032
The itchy locus encodes a novel ubiquitin protein ligase that is disrupted in a18H miceQ24308721
Muscle-specific RING finger 1 is a bona fide ubiquitin ligase that degrades cardiac troponin IQ24558612
Myosin accumulation and striated muscle myopathy result from the loss of muscle RING finger 1 and 3Q24673171
Molecular basis of physiological heart growth: fundamental concepts and new playersQ27006868
Molecular determinants for the recruitment of the ubiquitin-ligase MuRF-1 onto M-line titinQ27643507
The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signalingQ28240232
Human De-etiolated-1 regulates c-Jun by assembling a CUL4A ubiquitin ligaseQ28240243
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Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking taleQ28296128
JNK is required for effector T-cell function but not for T-cell activationQ28507174
Activated glycogen synthase-3 beta suppresses cardiac hypertrophy in vivoQ28511213
MEKK1 mediates the ubiquitination and degradation of c-Jun in response to osmotic stressQ28566574
The PHD domain of MEKK1 acts as an E3 ubiquitin ligase and mediates ubiquitination and degradation of ERK1/2Q28576814
A cytoplasmic inhibitor of the JNK signal transduction pathwayQ28586970
Regulation of cardiac hypertrophy by intracellular signalling pathwaysQ29615166
Role of insulin-like growth factors in embryonic and postnatal growthQ29620034
HL-1 cells: a cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyteQ29620367
Making sense of the COP9 signalosome. A regulatory protein complex conserved from Arabidopsis to humanQ33594290
mIGF-1/JNK1/SirT1 signaling confers protection against oxidative stress in the heart.Q34229899
The FOXO3a transcription factor regulates cardiac myocyte size downstream of AKT signalingQ34556111
Muscle ring finger 1 mediates cardiac atrophy in vivoQ34603561
Apoptosis signal-regulating kinase 1/p38 signaling pathway negatively regulates physiological hypertrophyQ34736062
The ubiquitin ligase MuRF1 protects against cardiac ischemia/reperfusion injury by its proteasome-dependent degradation of phospho-c-Jun.Q34760678
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The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-JunQ35458082
Cardiac proteasome activity in muscle ring finger-1 null mice at rest and following synthetic glucocorticoid treatment.Q35543645
Cardiac physiology at the cellular level: use of cultured HL-1 cardiomyocytes for studies of cardiac muscle cell structure and functionQ35651124
Back to your heart: ubiquitin proteasome system-regulated signal transductionQ35803035
Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteinsQ36088932
Muscle ring finger protein-1 inhibits PKC{epsilon} activation and prevents cardiomyocyte hypertrophyQ36322902
Human molecular genetic and functional studies identify TRIM63, encoding Muscle RING Finger Protein 1, as a novel gene for human hypertrophic cardiomyopathy.Q36350821
Glycogen synthase kinase-3beta is a negative regulator of cardiomyocyte hypertrophyQ36358042
Regulation of cardiac growth and coronary angiogenesis by the Akt/PKB signaling pathwayQ36689649
The fuzzy logic of physiological cardiac hypertrophyQ36772114
Myocardial AKT: the omnipresent nexusQ36908289
Muscle ring finger 1 and muscle ring finger 2 are necessary but functionally redundant during developmental cardiac growth and regulate E2F1-mediated gene expression in vivoQ37057089
Carboxyl terminus of Hsp70-interacting protein (CHIP) is required to modulate cardiac hypertrophy and attenuate autophagy during exercise.Q37164690
Regulation of nicotinic acetylcholine receptor turnover by MuRF1 connects muscle activity to endo/lysosomal and atrophy pathways.Q37179964
MAPK signalling in cardiovascular health and disease: molecular mechanisms and therapeutic targetsQ37254485
Early origins of cardiac hypertrophy: does cardiomyocyte attrition programme for pathological 'catch-up' growth of the heart?Q37256933
Cardiac muscle ring finger-1 increases susceptibility to heart failure in vivoQ37332162
Seek and destroy: the ubiquitin----proteasome system in cardiac disease.Q37628822
Molecular distinction between physiological and pathological cardiac hypertrophy: experimental findings and therapeutic strategiesQ37741316
The athlete's heart vs. the failing heart: can signaling explain the two distinct outcomes?Q37864469
Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathwaysQ39750571
The in vivo role of PtdIns(3,4,5)P3 binding to PDK1 PH domain defined by knockin mutationQ40561467
Muscle ring finger 1, but not muscle ring finger 2, regulates cardiac hypertrophy in vivoQ42750583
Jun turnover is controlled through JNK-dependent phosphorylation of the E3 ligase ItchQ46802020
Dysregulation of T lymphocyte function in itchy mice: a role for Itch in TH2 differentiation.Q52545197
Atrogin-1/MAFbx enhances simulated ischemia/reperfusion-induced apoptosis in cardiomyocytes through degradation of MAPK phosphatase-1 and sustained JNK activation.Q54501477
Defective T Cell Differentiation in the Absence of Jnk1Q58415329
Growth hormone in exercise: comparison of physiological and pharmacological stimuliQ67850954
Genetics of mouse growthQ77684683
Microarray analysis of Akt1 activation in transgenic mouse hearts reveals transcript expression profiles associated with compensatory hypertrophy and failureQ80044502
Akt1 is required for physiological cardiac growthQ83195147
Pressure-mediated hypertrophy and mechanical stretch induces IL-1 release and subsequent IGF-1 generation to maintain compensative hypertrophy by affecting Akt and JNK pathwaysQ84734687
P433issue7
P304page(s)E723-39
P577publication date2014-01-14
P1433published inAmerican Journal of Physiology - Endocrinology and MetabolismQ15765671
P1476titleMuscle RING finger-1 attenuates IGF-I-dependent cardiomyocyte hypertrophy by inhibiting JNK signaling
P478volume306

Reverse relations

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