| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1010107638 |
| P356 | DOI | 10.1038/NATURE11055 |
| P932 | PMC publication ID | 4974072 |
| P698 | PubMed publication ID | 22678294 |
| P5875 | ResearchGate publication ID | 225283265 |
| P2093 | author name string | Arnim Pause | |
| Martin Holcik | |||
| Stephen Lee | |||
| Marc R Fabian | |||
| Aleksandra Franovic | |||
| James Uniacke | |||
| Chet E Holterman | |||
| Mathieu D Jacob | |||
| Gabriel Lachance | |||
| Josianne Payette | |||
| P2860 | cites work | Hypoxia inducible factor activates the transforming growth factor-alpha/epidermal growth factor receptor growth stimulatory pathway in VHL(-/-) renal cell carcinoma cells | Q34536583 |
| Hypoxia-induced energy stress regulates mRNA translation and cell growth | Q35155445 | ||
| Translational up-regulation of the EGFR by tumor hypoxia provides a nonmutational explanation for its overexpression in human cancer | Q35928801 | ||
| Human cancers converge at the HIF-2alpha oncogenic axis. | Q37482150 | ||
| mRNA helicases: the tacticians of translational control | Q37856199 | ||
| Hypoxia-mediated selective mRNA translation by an internal ribosome entry site-independent mechanism | Q39026199 | ||
| A hypoxia-controlled cap-dependent to cap-independent translation switch in breast cancer. | Q40053351 | ||
| Eukaryotic protein synthesis: still a mystery | Q42737395 | ||
| Expression of hypoxia-inducible carbonic anhydrase-9 relates to angiogenic pathways and independently to poor outcome in non-small cell lung cancer | Q43787483 | ||
| Genomics illuminates a deadly brain cancer | Q48278547 | ||
| Widespread hypoxia-inducible expression of HIF-2alpha in distinct cell populations of different organs. | Q48422889 | ||
| Silencing of epidermal growth factor receptor suppresses hypoxia-inducible factor-2-driven VHL-/- renal cancer | Q95807715 | ||
| HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing | Q24291102 | ||
| Cell stress modulates the function of splicing regulatory protein RBM4 in translation control | Q24296006 | ||
| Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control | Q24304179 | ||
| Rapid and systematic analysis of the RNA recognition specificities of RNA-binding proteins | Q24308775 | ||
| Cloning and characterization of 4EHP, a novel mammalian eIF4E-related cap-binding protein | Q24315103 | ||
| RNA-binding motif protein 4 translocates to cytoplasmic granules and suppresses translation via argonaute2 during muscle cell differentiation | Q24321467 | ||
| Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function | Q24324452 | ||
| Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex | Q24559347 | ||
| Sequencing of 50 human exomes reveals adaptation to high altitude | Q24599025 | ||
| Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP | Q24630900 | ||
| Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation | Q27860876 | ||
| Untangling the ErbB signalling network | Q27860884 | ||
| Regulation of translation initiation in eukaryotes: mechanisms and biological targets | Q28111696 | ||
| Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1 | Q28141355 | ||
| Molecular mechanisms of translational control | Q29614568 | ||
| Translational control in stress and apoptosis | Q29615497 | ||
| Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway | Q29617805 | ||
| Regulation of cap-dependent translation by eIF4E inhibitory proteins | Q29622831 | ||
| RNAcontext: a new method for learning the sequence and structure binding preferences of RNA-binding proteins | Q30985446 | ||
| Attenuation of proteasome-induced proteolysis in skeletal muscle by {beta}-hydroxy-{beta}-methylbutyrate in cancer-induced muscle loss | Q33984500 | ||
| Characterizing the interaction of the mammalian eIF4E-related protein 4EHP with 4E-BP1. | Q34314566 | ||
| P433 | issue | 7401 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 126-129 | |
| P577 | publication date | 2012-05-06 | |
| P1433 | published in | Nature | Q180445 |
| P1476 | title | An oxygen-regulated switch in the protein synthesis machinery | |
| P478 | volume | 486 |
| Q34227573 | 4EGI-1 targets breast cancer stem cells by selective inhibition of translation that persists in CSC maintenance, proliferation and metastasis |
| Q41658238 | A Cap for Every Occasion: Alternative eIF4F Complexes |
| Q47315154 | A Unique ISR Program Determines Cellular Responses to Chronic Stress. |
| Q36238117 | A forward genetic screen reveals novel independent regulators of ULBP1, an activating ligand for natural killer cells |
| Q96022843 | A network of RNA-binding proteins controls translation efficiency to activate anaerobic metabolism |
| Q37010219 | A splicing isoform of TEAD4 attenuates the Hippo-YAP signalling to inhibit tumour proliferation |
| Q34579255 | A test for ancient selective sweeps and an application to candidate sites in modern humans |
| Q64063099 | A threonyl-tRNA synthetase-mediated translation initiation machinery |
| Q102058970 | A translational program that suppresses metabolism to shield the genome |
| Q92690566 | ARNT-dependent HIF-2 transcriptional activity is not sufficient to regulate downstream target genes in neuroblastoma |
| Q38206125 | Aberrant expression of RCAN1 in Alzheimer's pathogenesis: a new molecular mechanism and a novel drug target |
| Q91961385 | Activation of Hypoxia-Inducible Factor Signaling Modulates the RNA Protein Interactome in Caenorhabditis elegans |
| Q50967876 | Analysis of Cap-binding Proteins in Human Cells Exposed to Physiological Oxygen Conditions. |
| Q37583517 | Anthrax lethal toxin inhibits translation of hypoxia-inducible factor 1α and causes decreased tolerance to hypoxic stress |
| Q37562355 | Anti-angiogenic Therapy in Cancer: Downsides and New Pivots for Precision Medicine |
| Q35158420 | Assessment of selective mRNA translation in mammalian cells by polysome profiling |
| Q59796441 | Astrocyte HIF-2α supports learning in a passive avoidance paradigm under hypoxic stress |
| Q40815627 | Bayesian hidden Markov models to identify RNA-protein interaction sites in PAR-CLIP. |
| Q47281734 | Beyond Transcription: Roles of Transcription Factors in Pre-mRNA Splicing. |
| Q47705324 | CLOCK stabilizes CYCLE to initiate clock function in Drosophila |
| Q100693083 | Cancer Plasticity: The Role of mRNA Translation |
| Q45141966 | Cap-binding protein 4EHP effects translation silencing by microRNAs |
| Q90119301 | Cellular adaptation to hypoxia through hypoxia inducible factors and beyond |
| Q26781248 | Combinatorial Control of mRNA Fates by RNA-Binding Proteins and Non-Coding RNAs |
| Q90443017 | Comparative proteomics of the two T. brucei PABPs suggests that PABP2 controls bulk mRNA |
| Q28245737 | Context-dependent control of alternative splicing by RNA-binding proteins |
| Q47125075 | DDX3 regulates endoplasmic reticulum stress-induced ATF4 expression |
| Q33694616 | DNMT3a epigenetic program regulates the HIF-2α oxygen-sensing pathway and the cellular response to hypoxia |
| Q26778957 | Development, Maintenance, and Reversal of Multiple Drug Resistance: At the Crossroads of TFPI1, ABC Transporters, and HIF1 |
| Q35587700 | Differential HIF-1α and HIF-2α Expression in Mammary Epithelial Cells during Fat Pad Invasion, Lactation, and Involution |
| Q36117958 | Distinct recruitment of human eIF4E isoforms to processing bodies and stress granules |
| Q36490260 | EFNA3 long noncoding RNAs induced by hypoxia promote metastatic dissemination |
| Q34240895 | Elevated SRPK1 lessens apoptosis in breast cancer cells through RBM4-regulated splicing events |
| Q39854446 | Elongation Factor 2 Kinase Is Regulated by Proline Hydroxylation and Protects Cells during Hypoxia |
| Q39187160 | Enhancement of protein production via the strong DIT1 terminator and two RNA-binding proteins in Saccharomyces cerevisiae. |
| Q24622503 | Environmental cues induce a long noncoding RNA-dependent remodeling of the nucleolus |
| Q48103585 | Evolution: Oxygen and early animals |
| Q36044216 | GPRC5A suppresses protein synthesis at the endoplasmic reticulum to prevent radiation-induced lung tumorigenesis |
| Q38830228 | Global analysis of physical and functional RNA targets of hnRNP L reveals distinct sequence and epigenetic features of repressed and enhanced exons |
| Q27324988 | HIF- and non-HIF-regulated hypoxic responses require the estrogen-related receptor in Drosophila melanogaster |
| Q41988445 | HIF-3α1 promotes colorectal tumor cell growth by activation of JAK-STAT3 signaling |
| Q36998209 | HIF2α contributes to antiestrogen resistance via positive bilateral crosstalk with EGFR in breast cancer cells. |
| Q27013905 | High-throughput characterization of protein-RNA interactions |
| Q38784269 | Human Cells Cultured under Physiological Oxygen Utilize Two Cap-binding Proteins to recruit Distinct mRNAs for Translation |
| Q49391561 | Hypoxia activates cadherin-22 synthesis via eIF4E2 to drive cancer cell migration, invasion and adhesion |
| Q41282753 | Hypoxia and Hypoglycemia synergistically regulate mRNA stability. |
| Q50070013 | Hypoxia and hypoxia-inducible factors in neuroblastoma |
| Q26799950 | Hypoxia signaling pathways: modulators of oxygen-related organelles |
| Q38913214 | Hypoxia, pseudohypoxia and cellular differentiation |
| Q55419613 | Hypoxia-Inducible Factor 2-Dependent Pathways Driving Von Hippel-Lindau-Deficient Renal Cancer. |
| Q35237075 | Hypoxia-induced gene expression results from selective mRNA partitioning to the endoplasmic reticulum. |
| Q38078689 | Hypoxia-inducible factor prolyl hydroxylases as targets for neuroprotection by "antioxidant" metal chelators: From ferroptosis to stroke. |
| Q36967260 | Hypoxia-inducible factor-1α (HIF-1α) promotes cap-dependent translation of selective mRNAs through up-regulating initiation factor eIF4E1 in breast cancer cells under hypoxia conditions |
| Q37620078 | Hypoxia-inducible factors link iron homeostasis and erythropoiesis |
| Q49569525 | Hypoxia-mediated translational activation of ITGB3 in breast cancer cells enhances TGF-β signaling and malignant features in vitro and in vivo |
| Q28384176 | Insulin promotes glucose consumption via regulation of miR-99a/mTOR/PKM2 pathway |
| Q31133279 | Investigating the consequences of eIF4E2 (4EHP) interaction with 4E-transporter on its cellular distribution in HeLa cells |
| Q92376588 | Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication Interferes with mTORC1 Regulation of Autophagy and Viral Protein Synthesis |
| Q47753117 | Major splice variants and multiple polyadenylation site utilization in mRNAs encoding human translation initiation factors eIF4E1 and eIF4E3 regulate the translational regulators? |
| Q92615623 | Metabolic stress activates an ERK/hnRNPK/DDX3X pathway in pancreatic β cells |
| Q59137532 | Metformin blocks MYC protein synthesis in colorectal cancer via mTOR-4EBP-eIF4E and MNK1-eIF4G-eIF4E signaling |
| Q28387581 | Mitochondrial Cytochrome c Oxidase Biogenesis Is Regulated by the Redox State of a Heme-Binding Translational Activator |
| Q35106440 | Mitochondrial respiratory function induces endogenous hypoxia |
| Q38700673 | Modifying the maker: Oxygenases target ribosome biology |
| Q41432736 | N6-methyladenosine is required for the hypoxic stabilization of specific mRNAs. |
| Q33853235 | New frontiers in translational control of the cancer genome |
| Q44403569 | No Escaping the Rat Race: Simulated Night Shift Work Alters the Time-of-Day Variation in BMAL1 Translational Activity in the Prefrontal Cortex |
| Q37631808 | Overexpression of FGF9 in colon cancer cells is mediated by hypoxia-induced translational activation |
| Q26795484 | Oxygen Sensing and Homeostasis |
| Q35622581 | Oxygen and glucose deprivation induces widespread alterations in mRNA translation within 20 minutes |
| Q38080837 | Oxygen sensing and hypoxia signalling pathways in animals: the implications of physiology for cancer |
| Q47177113 | Oxygen-Sensitive Remodeling of Central Carbon Metabolism by Archaic eIF5B. |
| Q38704713 | Pharmacological targeting of the HIF hydroxylases--A new field in medicine development |
| Q30245567 | Placental Origins of Chronic Disease |
| Q39436212 | Post-transcriptional control of gene expression following stress: the role of RNA-binding proteins |
| Q36398266 | Post-transcriptional regulation in cancer progression : Microenvironmental control of alternative splicing and translation |
| Q26781470 | Prognostic Significance of Hypoxia-Inducible Factor Expression in Renal Cell Carcinoma: A PRISMA-compliant Systematic Review and Meta-Analysis |
| Q37024168 | Prognostic value of decreased expression of RBM4 in human gastric cancer |
| Q38615964 | Ribosome profiling reveals translational regulation of mammalian cells in response to hypoxic stress |
| Q47654911 | Role of hypoxia in Diffuse Large B-cell Lymphoma: Metabolic repression and selective translation of HK2 facilitates development of DLBCL. |
| Q37301035 | Signaling hypoxia by hypoxia-inducible factor protein hydroxylases: a historical overview and future perspectives |
| Q35079777 | Stimulating retinal blood vessel protection with hypoxia-inducible factor stabilization: identification of novel small-molecule hydrazones to inhibit hypoxia-inducible factor prolyl hydroxylase (an American Ophthalmological Society thesis). |
| Q90539087 | Stress-Induced Translational Regulation Mediated by RNA Binding Proteins: Key Links to β-Cell Failure in Diabetes |
| Q90284560 | Subcellular Localization Signals of bHLH-PAS Proteins: Their Significance, Current State of Knowledge and Future Perspectives |
| Q36593913 | Systemic Reprogramming of Translation Efficiencies on Oxygen Stimulus |
| Q47611824 | Targeting HIF2 in Clear Cell Renal Cell Carcinoma |
| Q100455154 | Targeting the HIF2-VEGF axis in renal cell carcinoma |
| Q35660035 | The Circadian Protein BMAL1 Regulates Translation in Response to S6K1-Mediated Phosphorylation |
| Q38644137 | The Hypoxia-Adenosine Link during Inflammation. |
| Q90611810 | The Lsm1-7/Pat1 complex binds to stress-activated mRNAs and modulates the response to hyperosmotic shock |
| Q92339716 | The RNA-Protein Interactome of Differentiated Kidney Tubular Epithelial Cells |
| Q46774762 | The Role of Cytoplasmic mRNA Cap-Binding Protein Complexes in Trypanosoma brucei and Other Trypanosomatids. |
| Q92156491 | The Zebrafish Xenograft Platform-A Novel Tool for Modeling KSHV-Associated Diseases |
| Q38854723 | The action of HIF-3α variants on HIF-2α-HIF-1β heterodimer formation is directly probed in live cells |
| Q47215309 | The eIF4E2-Directed Hypoxic Cap-Dependent Translation Machinery Reveals Novel Therapeutic Potential for Cancer Treatment |
| Q39148511 | The induction of MIG6 under hypoxic conditions is critical for dormancy in primary cultured lung cancer cells with activating EGFR mutations |
| Q34157516 | The splicing factor RBM4 controls apoptosis, proliferation, and migration to suppress tumor progression |
| Q26747806 | Therapeutic targeting of hypoxia and hypoxia-inducible factors in cancer |
| Q89789366 | Transglutaminase 2 mediates hypoxia-induced selective mRNA translation via polyamination of 4EBPs |
| Q64244241 | Translating the Hypoxic Response-the Role of HIF Protein Translation in the Cellular Response to Low Oxygen |
| Q58374805 | Translation acrobatics: how cancer cells exploit alternate modes of translational initiation |
| Q64276738 | Translational Control of Canonical and Non-Canonical Translation Initiation Factors at the Sea Urchin Egg to Embryo Transition |
| Q41123932 | Translational Dysregulation in Cancer: Molecular Insights and Potential Clinical Applications in Biomarker Development |
| Q27002504 | Translational control by 3'-UTR-binding proteins |
| Q42348648 | Translational control of mRNAs by 3'-Untranslated region binding proteins. |
| Q52585822 | Translatome analysis at the egg-to-embryo transition in sea urchin. |
| Q36174099 | Tristetraprolin Recruits Eukaryotic Initiation Factor 4E2 To Repress Translation of AU-Rich Element-Containing mRNAs |
| Q39321880 | Versatility of the translational machinery during stress: changing partners to keep dancing |
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| Q64100298 | mRNA-to-protein translation in hypoxia |
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