A parsimonious model for gene regulation by miRNAs.

scientific article published on February 2011

A parsimonious model for gene regulation by miRNAs. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1126/SCIENCE.1191138
P8608Fatcat IDrelease_sdmr7qifezd6lmm5uwkupkzom4
P932PMC publication ID3955125
P698PubMed publication ID21292970

P50authorSergej DjuranovicQ56153295
P2093author name stringAli Nahvi
Rachel Green
P2860cites workMicroRNA Inhibition of Translation Initiation in Vitro by Targeting the Cap-Binding Complex eIF4FQ58880697
An mRNA m7G cap binding-like motif within human Ago2 represses translationQ24306727
Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylationQ24310618
Let-7 microRNA-mediated mRNA deadenylation and translational repression in a mammalian cell-free systemQ24328771
mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexesQ24554481
Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profilingQ24651977
The impact of microRNAs on protein outputQ24653549
An expanded seed sequence definition accounts for full regulation of the hid 3' UTR by bantam miRNAQ24655135
Deadenylation is a widespread effect of miRNA regulationQ24655139
Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplexQ27653175
Nucleation, propagation and cleavage of target RNAs in Ago silencing complexesQ27657724
Structural basis for 5'-nucleotide base-specific recognition of guide RNA by human AGO2Q27661958
Mammalian microRNAs predominantly act to decrease target mRNA levelsQ27860535
Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegansQ27860584
Widespread changes in protein synthesis induced by microRNAsQ27860886
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAsQ27861053
Regulation of translation initiation in eukaryotes: mechanisms and biological targetsQ28111696
MicroRNA silencing through RISC recruitment of eIF6Q28118262
bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in DrosophilaQ28131827
The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translationQ28143010
Relief of microRNA-mediated translational repression in human cells subjected to stressQ28246349
Structural basis for overhang-specific small interfering RNA recognition by the PAZ domainQ28262499
Inhibition of translational initiation by Let-7 MicroRNA in human cellsQ28265842
Regulation by let-7 and lin-4 miRNAs results in target mRNA degradationQ28268899
Regulation of mRNA translation and stability by microRNAsQ29547304
Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAsQ29547837
MicroRNAs direct rapid deadenylation of mRNAQ29614566
General translational repression by activators of mRNA decappingQ29614567
Crystal structure of Argonaute and its implications for RISC slicer activityQ29614980
Perspective: machines for RNAiQ29616378
Regulation of cap-dependent translation by eIF4E inhibitory proteinsQ29622831
Concordant regulation of translation and mRNA abundance for hundreds of targets of a human microRNAQ30878993
Lipoxygenase mRNA silencing in erythroid differentiation: The 3'UTR regulatory complex controls 60S ribosomal subunit joiningQ32025196
Drosophila miR2 primarily targets the m7GpppN cap structure for translational repressionQ33506829
Mutations in translation initiation factors lead to increased rates of deadenylation and decapping of mRNAs in Saccharomyces cerevisiaeQ33958855
Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi proteinQ33986097
Sorting of small RNAs into Arabidopsis argonaute complexes is directed by the 5' terminal nucleotideQ34308999
Short RNAs repress translation after initiation in mammalian cells.Q34495292
Drosophila argonaute1 and argonaute2 employ distinct mechanisms for translational repression.Q34658219
Quality control of eukaryotic mRNA: safeguarding cells from abnormal mRNA functionQ34658630
A three-dimensional view of the molecular machinery of RNA interferenceQ34926596
MicroRNA-repressed mRNAs contain 40S but not 60S componentsQ36535338
Argonaute: A scaffold for the function of short regulatory RNAsQ36618358
Computational analysis of miRNA-mediated repression of translation: implications for models of translation initiation inhibitionQ36800464
Getting to the root of miRNA-mediated gene silencingQ37055551
Repression of C. elegans microRNA targets at the initiation level of translation requires GW182 proteinsQ37087245
The growing catalog of small RNAs and their association with distinct Argonaute/Piwi family membersQ37089444
Nucleic acid 3'-end recognition by the Argonaute2 PAZ domainQ38340880
Allosteric regulation of Argonaute proteins by miRNAs.Q39475198
The silencing domain of GW182 interacts with PABPC1 to promote translational repression and degradation of microRNA targets and is required for target releaseQ39792632
Human let-7a miRNA blocks protein production on actively translating polyribosomesQ40204130
Spatial regulation of beta-actin translation by Src-dependent phosphorylation of ZBP1.Q40347909
Structural insights into mRNA recognition from a PIWI domain-siRNA guide complexQ42184881
Characterization of the miRNA-RISC loading complex and miRNA-RISC formed in the Drosophila miRNA pathwayQ43103477
Role of GW182 proteins and PABPC1 in the miRNA pathway: a sense of déjà vu.Q44306252
GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decayQ46698175
Drosophila miR2 induces pseudo-polysomes and inhibits translation initiation.Q52679873
P433issue6017
P407language of work or nameEnglishQ1860
P304page(s)550-553
P577publication date2011-02-01
P1433published inScienceQ192864
P1476titleA parsimonious model for gene regulation by miRNAs
P478volume331

Reverse relations

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Q36509095microRNA-independent recruitment of Argonaute 1 to nanos mRNA through the Smaug RNA-binding protein
Q38034250microRNAs in skeletal muscle differentiation and disease
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