A var gene upstream element controls protein synthesis at the level of translation initiation in Plasmodium falciparum

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A var gene upstream element controls protein synthesis at the level of translation initiation in Plasmodium falciparum is …
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P819ADS bibcode2014PLoSO...9j0183B
P356DOI10.1371/JOURNAL.PONE.0100183
P932PMC publication ID4061111
P698PubMed publication ID24937593
P5875ResearchGate publication ID263205698

P50authorNicolas M BrancucciQ56453021
Kathrin WitmerQ56810091
P2093author name stringChristoph Schmid
Till S Voss
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Dihydrofolate reductase protein inhibits its own translation by binding to dihydrofolate reductase mRNA sequences within the coding regionQ73745094
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Chromatin associated sense and antisense noncoding RNAs are transcribed from the var gene family of virulence genes of the malaria parasite Plasmodium falciparumQ37034267
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Dynamic histone H3 epigenome marking during the intraerythrocytic cycle of Plasmodium falciparumQ37239022
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A molecular switch in the efficiency of translation reinitiation controls expression of var2csa, a gene implicated in pregnancy-associated malariaQ37610154
Plasmodium falciparum erythrocyte membrane protein 1 is a parasitized erythrocyte receptor for adherence to CD36, thrombospondin, and intercellular adhesion molecule 1.Q37659330
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Multiple var gene transcripts are expressed in Plasmodium falciparum infected erythrocytes selected for adhesion.Q38300351
A sequence element associated with thePlasmodium falciparumKAHRP gene is the site of developmentally regulated protein-DNA interactionsQ40422655
Characterization of a cis-acting regulatory element in the protein-coding region of human dihydrofolate reductase mRNA.Q40609122
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Translational regulation of the synthesis of dihydrofolate reductaseQ41584326
Genome-wide profiling of chromosome interactions in Plasmodium falciparum characterizes nuclear architecture and reconfigurations associated with antigenic variationQ41877614
5' flanking region of var genes nucleate histone modification patterns linked to phenotypic inheritance of virulence traits in malaria parasitesQ41935611
Comparative genomic analysis of novel conserved peptide upstream open reading frames in Drosophila melanogaster and other dipteran speciesQ41980619
Heterochromatin silencing and locus repositioning linked to regulation of virulence genes in Plasmodium falciparumQ46429981
Perinuclear localization of chromatin facilitates transcriptional silencingQ47675987
Var gene diversity in Plasmodium falciparum is generated by frequent recombination eventsQ47815758
Analysis of Plasmodium falciparum PfEMP-1/var genes suggests that recombination rearranges constrained sequencesQ47853007
Frequent ectopic recombination of virulence factor genes in telomeric chromosome clusters of P. falciparumQ47873714
Malaria. Cooperative silencing elements in var genesQ47888988
Plasmodium falciparum var genes are regulated by two regions with separate promoters, one upstream of the coding region and a second within the intronQ47931515
A var gene promoter controls allelic exclusion of virulence genes in Plasmodium falciparum malariaQ48021609
H2A.Z and H2B.Z double-variant nucleosomes define intergenic regions and dynamically occupy var gene promoters in the malaria parasite Plasmodium falciparumQ48032398
Evidence that Plasmodium falciparum chromosome end clusters are cross-linked by protein and are the sites of both virulence gene silencing and activationQ48035005
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectPlasmodium falciparumQ311383
P304page(s)e100183
P577publication date2014-06-17
P1433published inPLOS OneQ564954
P1476titleA var gene upstream element controls protein synthesis at the level of translation initiation in Plasmodium falciparum
P478volume9