| scholarly article | Q13442814 |
| P356 | DOI | 10.1080/17474124.2016.1179575 |
| P698 | PubMed publication ID | 27093595 |
| P50 | author | Ming-Hua Zheng | Q37831296 |
| Sven Van Poucke | Q39062665 | ||
| P2093 | author name string | Jian Xiao | |
| Xiao-Kun Li | |||
| Martin Braddock | |||
| Wen-Yue Liu | |||
| Wei-Min Jin | |||
| Fa-Ling Wu | |||
| P2860 | cites work | Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1 | Q22011167 |
| XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor | Q24292102 | ||
| Roles of CHOP/GADD153 in endoplasmic reticulum stress | Q24302185 | ||
| TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver | Q24304147 | ||
| Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response | Q24304232 | ||
| Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma | Q24598483 | ||
| Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma | Q24600346 | ||
| Potent and selective inhibitors of the inositol-requiring enzyme 1 endoribonuclease | Q24628936 | ||
| STIM proteins: dynamic calcium signal transducers | Q24633618 | ||
| Different types of ground glass hepatocytes in chronic hepatitis B virus infection contain specific pre-S mutants that may induce endoplasmic reticulum stress | Q24672497 | ||
| The Potential Role of Iron and Copper in Pediatric Obesity and Nonalcoholic Fatty Liver Disease | Q26798153 | ||
| Induction of incomplete autophagic response by hepatitis C virus via the unfolded protein response | Q27487012 | ||
| The autophagy machinery is required to initiate hepatitis C virus replication | Q27489377 | ||
| Structure and mechanism of action of the hydroxy–aryl–aldehyde class of IRE1 endoribonuclease inhibitors | Q27640568 | ||
| Depletion of cyclophilins B and C leads to dysregulation of endoplasmic reticulum redox homeostasis | Q28243241 | ||
| Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways | Q28365886 | ||
| PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation | Q28507769 | ||
| Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
| CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum | Q28509611 | ||
| XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands | Q28510479 | ||
| Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha | Q28512201 | ||
| CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum | Q28512249 | ||
| Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes | Q28575190 | ||
| ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals | Q28646129 | ||
| Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response | Q29547299 | ||
| The unfolded protein response: from stress pathway to homeostatic regulation | Q29547396 | ||
| Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes | Q29615503 | ||
| A central role for JNK in obesity and insulin resistance | Q29619778 | ||
| Increase in endoplasmic reticulum stress-related proteins and genes in adipose tissue of obese, insulin-resistant individuals | Q33345339 | ||
| Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance. | Q33896647 | ||
| Human hepatitis C virus NS5A protein alters intracellular calcium levels, induces oxidative stress, and activates STAT-3 and NF-kappa B. | Q33933056 | ||
| Autophagy in HCV infection: keeping fat and inflammation at bay | Q34069393 | ||
| Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1. | Q34148542 | ||
| Activation of the ATF6, XBP1 and grp78 genes in human hepatocellular carcinoma: a possible involvement of the ER stress pathway in hepatocarcinogenesis | Q34192744 | ||
| Intramembrane proteolysis and endoplasmic reticulum retention of hepatitis C virus core protein | Q34193354 | ||
| Fibroblast growth factor 21 is regulated by the IRE1α-XBP1 branch of the unfolded protein response and counteracts endoplasmic reticulum stress-induced hepatic steatosis | Q34396839 | ||
| Lipid metabolism and liver inflammation. II. Fatty liver disease and fatty acid oxidation | Q34512108 | ||
| IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates. | Q39814866 | ||
| A novel endoplasmic reticulum export signal: proline at the +2-position from the signal peptide cleavage site | Q39816406 | ||
| Knockdown of autophagy-related gene decreases the production of infectious hepatitis C virus particles | Q39821948 | ||
| Chemical biology investigation of cell death pathways activated by endoplasmic reticulum stress reveals cytoprotective modulators of ASK1. | Q39917756 | ||
| Mammalian BiP controls posttranslational ER translocation of the hepatitis B virus large envelope protein. | Q39950009 | ||
| Hepatitis B virus X protein (HBx) activates ATF6 and IRE1-XBP1 pathways of unfolded protein response | Q40210691 | ||
| Gastric bypass surgery is protective from high-fat diet-induced non-alcoholic fatty liver disease and hepatic endoplasmic reticulum stress | Q40216244 | ||
| Hepatitis C virus core triggers apoptosis in liver cells by inducing ER stress and ER calcium depletion | Q40421534 | ||
| XBP1 is essential for survival under hypoxic conditions and is required for tumor growth. | Q40519913 | ||
| CCN1/CYR61 overexpression in hepatic stellate cells induces ER stress-related apoptosis | Q40930580 | ||
| Genomewide Histone H3 Lysine 9 Acetylation Profiling in CD4+ T Cells Revealed Endoplasmic Reticulum Stress Deficiency in Patients with Acute-on-chronic Liver Failure | Q41108917 | ||
| Baicalein protects against polymicrobial sepsis-induced liver injury via inhibition of inflammation and apoptosis in mice. | Q41586344 | ||
| Baicalein Triggers Autophagy and Inhibits the Protein Kinase B/Mammalian Target of Rapamycin Pathway in Hepatocellular Carcinoma HepG2 Cells. | Q41918719 | ||
| UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators. | Q42041480 | ||
| Autophagy and RNA virus interactomes reveal IRGM as a common target. | Q42051450 | ||
| The involvement of endoplasmic reticulum stress in bile acid-induced hepatocellular injury | Q42128127 | ||
| ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC development | Q42199386 | ||
| Involvement of androgen receptor and glucose-regulated protein 78 kDa in human hepatocarcinogenesis | Q42234477 | ||
| Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stress | Q42451739 | ||
| Integrative cross-omics analysis in primary mouse hepatocytes unravels mechanisms of cyclosporin A-induced hepatotoxicity | Q42704761 | ||
| Corrigendum: Serotonin Deficiency Exacerbates Acetaminophen-Induced Liver Toxicity In Mice | Q43170267 | ||
| BGP-15 inhibits caspase-independent programmed cell death in acetaminophen-induced liver injury | Q43237256 | ||
| Regulation of ER molecular chaperone prevents bone loss in a murine model for osteoporosis | Q43275582 | ||
| Paracetamol-induced renal tubular injury: a role for ER stress | Q44745219 | ||
| Activation and dysregulation of the unfolded protein response in nonalcoholic fatty liver disease | Q44934521 | ||
| Chronic ethanol feeding and folate deficiency activate hepatic endoplasmic reticulum stress pathway in micropigs | Q45261151 | ||
| The protective effect of a newly developed molecular chaperone-inducer against mouse ischemic acute kidney injury | Q46140551 | ||
| Predominant role of sterol response element binding proteins (SREBP) lipogenic pathways in hepatic steatosis in the murine intragastric ethanol feeding model | Q46243875 | ||
| Sodium 4-phenylbutyrate protects against liver ischemia reperfusion injury by inhibition of endoplasmic reticulum-stress mediated apoptosis | Q46695184 | ||
| 6-Shogaol induces cell cycle arrest and apoptosis in human hepatoma cells through pleiotropic mechanisms | Q46711184 | ||
| Ursolic acid inhibits the development of nonalcoholic fatty liver disease by attenuating endoplasmic reticulum stress | Q46740738 | ||
| CHOP deficiency attenuates cholestasis-induced liver fibrosis by reduction of hepatocyte injury | Q46823993 | ||
| Direct monitoring of in vivo ER stress during the development of insulin resistance with ER stress-activated indicator transgenic mice. | Q46857277 | ||
| Sinulariolide induced hepatocellular carcinoma apoptosis through activation of mitochondrial-related apoptotic and PERK/eIF2α/ATF4/CHOP pathway | Q47709551 | ||
| Activation of mammalian IRE1alpha upon ER stress depends on dissociation of BiP rather than on direct interaction with unfolded proteins | Q50336381 | ||
| Melatonin inhibits autophagy and endoplasmic reticulum stress in mice with carbon tetrachloride-induced fibrosis. | Q50445895 | ||
| Alpha-1 antitrypsin Z protein (PiZ) increases hepatic fibrosis in a murine model of cholestasis. | Q50684835 | ||
| Phagocytic function of Kupffer cells in mouse nonalcoholic fatty liver disease models: Evaluation with superparamagnetic iron oxide. | Q53063351 | ||
| Atf6α-null mice are glucose intolerant due to pancreatic β-cell failure on a high-fat diet but partially resistant to diet-induced insulin resistance. | Q53181684 | ||
| Endoplasmic reticulum stress and disturbed calcium homeostasis are involved in copper-induced alteration in hepatic lipid metabolism in yellow catfish Pelteobagrus fulvidraco. | Q53266566 | ||
| A possible involvement of endoplasmic reticulum stress in biliary epithelial autophagy and senescence in primary biliary cirrhosis. | Q53648391 | ||
| Free fatty acids induce transglutaminase 2-dependent apoptosis in hepatocytes via ER stress-stimulated PERK pathways. | Q54590342 | ||
| Fenofibrate treatment attenuated chronic endoplasmic reticulum stress in the liver of nonalcoholic fatty liver disease mice. | Q55060806 | ||
| Tauroursodeoxycholic acid prevents stress induced aggregation of proteins in vitro and promotes PERK activation in HepG2 cells. | Q55068738 | ||
| Activation of the Akt-NF-kappaB pathway by subtilase cytotoxin through the ATF6 branch of the unfolded protein response | Q37389501 | ||
| Carbamazepine suppresses calpain-mediated autophagy impairment after ischemia/reperfusion in mouse livers | Q37402779 | ||
| Mechanisms and implications of reactive oxygen species generation during the unfolded protein response: roles of endoplasmic reticulum oxidoreductases, mitochondrial electron transport, and NADPH oxidase | Q37456875 | ||
| Berberine reduces endoplasmic reticulum stress and improves insulin signal transduction in Hep G2 cells | Q37728794 | ||
| The Role of Lipid Metabolism in the Pathogenesis of Alcoholic and Nonalcoholic Hepatic Steatosis | Q37801599 | ||
| Hepatic fibrosis and carcinogenesis in α1-antitrypsin deficiency: a prototype for chronic tissue damage in gain-of-function disorders | Q37855343 | ||
| Role of obesity and lipotoxicity in the development of nonalcoholic steatohepatitis: pathophysiology and clinical implications | Q37983300 | ||
| Ultrastructural examination of renal tubular epithelial cells and hepatocytes in the course of chronic cyclosporin A treatment--a possible link to oxidative stress | Q38123233 | ||
| Targeting the unfolded protein response in disease. | Q38132652 | ||
| The role of fibroblast growth factor 21 in the pathogenesis of liver disease: a novel predictor and therapeutic target | Q38235454 | ||
| Targeting fibroblast growth factor 19 in liver disease: a potential biomarker and therapeutic target. | Q38303270 | ||
| Cannabidiol causes activated hepatic stellate cell death through a mechanism of endoplasmic reticulum stress-induced apoptosis | Q38347321 | ||
| Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice | Q38354947 | ||
| Acetylshikonin induces apoptosis of hepatitis B virus X protein-expressing human hepatocellular carcinoma cells via endoplasmic reticulum stress | Q38438776 | ||
| Autophagy in ethanol-exposed liver disease | Q38549452 | ||
| Cystatin C attenuates insulin signaling transduction by promoting endoplasmic reticulum stress in hepatocytes | Q38817883 | ||
| Selective Regulation of FGF19 and FGF21 Expression by Cellular and Nutritional Stress | Q38866463 | ||
| The flavone apigenin blocks nuclear translocation of sterol regulatory element-binding protein-2 in the hepatic cells WRL-68. | Q38874423 | ||
| Mechanisms of alcohol-induced endoplasmic reticulum stress and organ injuries | Q38898700 | ||
| Synthesis and biological evaluation of geldanamycin analogs against human cancer cells. | Q38909847 | ||
| Synthesis and anticancer activities of a novel class of mono- and di-metallic Pt(II)(salicylaldiminato)(DMSO or Picolino)Cl complexes. | Q38928386 | ||
| 5-Fluorouracil combined with apigenin enhances anticancer activity through mitochondrial membrane potential (ΔΨm)-mediated apoptosis in hepatocellular carcinoma | Q38943320 | ||
| Role of endoplasmic reticulum stress in light-induced photoreceptor degeneration in mice | Q39231671 | ||
| Baicalein protects HT22 murine hippocampal neuronal cells against endoplasmic reticulum stress-induced apoptosis through inhibition of reactive oxygen species production and CHOP induction | Q39642134 | ||
| Mechanism of arylating quinone toxicity involving Michael adduct formation and induction of endoplasmic reticulum stress | Q34574408 | ||
| Nucleobindin 1 controls the unfolded protein response by inhibiting ATF6 activation | Q34661064 | ||
| Rapamycin protection of livers from ischemia and reperfusion injury is dependent on both autophagy induction and mammalian target of rapamycin complex 2-Akt activation | Q34747296 | ||
| Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress | Q34801719 | ||
| The contribution of endoplasmic reticulum stress to liver diseases | Q34860549 | ||
| The Hsp90 inhibitor SNX-2112 induces apoptosis of human hepatocellular carcinoma cells: the role of ER stress | Q35105119 | ||
| Phosphorylation of the alpha subunit of eukaryotic initiation factor 2 is required for activation of NF-kappaB in response to diverse cellular stresses | Q35169632 | ||
| Resveratrol enhances palmitate-induced ER stress and apoptosis in cancer cells | Q35462357 | ||
| Alcohol disrupts endoplasmic reticulum function and protein secretion in hepatocytes | Q35478792 | ||
| 4-Phenylbutyrate stimulates Hsp70 expression through the Elp2 component of elongator and STAT-3 in cystic fibrosis epithelial cells | Q35639867 | ||
| Fibroblast growth factor 21 prevents atherosclerosis by suppression of hepatic sterol regulatory element-binding protein-2 and induction of adiponectin in mice. | Q35648897 | ||
| Hydrogen sulfide suppresses endoplasmic reticulum stress-induced endothelial-to-mesenchymal transition through Src pathway | Q35866044 | ||
| Knockdown of autophagy enhances the innate immune response in hepatitis C virus-infected hepatocytes | Q35910776 | ||
| Insulin resistance, ceramide accumulation, and endoplasmic reticulum stress in human chronic alcohol-related liver disease | Q35944938 | ||
| Replication of hepatitis C virus RNA on autophagosomal membranes | Q36002897 | ||
| Myeloid-specific SIRT1 Deletion Aggravates Hepatic Inflammation and Steatosis in High-fat Diet-fed Mice | Q36006934 | ||
| Complementary cell-based high-throughput screens identify novel modulators of the unfolded protein response | Q36029924 | ||
| Endoplasmic reticulum stress in liver disease | Q36031838 | ||
| Protective Effects of Alisma orientale Extract against Hepatic Steatosis via Inhibition of Endoplasmic Reticulum Stress | Q36324486 | ||
| Hepatitis B and C virus-induced hepatitis: Apoptosis, autophagy, and unfolded protein response | Q36373611 | ||
| Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure | Q36413970 | ||
| Protein quality control in the early secretory pathway | Q36446833 | ||
| PDIA6 regulates insulin secretion by selectively inhibiting the RIDD activity of IRE1. | Q36467006 | ||
| Insulin resistance, ceramide accumulation and endoplasmic reticulum stress in experimental chronic alcohol-induced steatohepatitis | Q36469896 | ||
| ER stress: can the liver cope? | Q36517489 | ||
| Proteasome inhibitor induces apoptosis through induction of endoplasmic reticulum stress. | Q36544379 | ||
| Endoplasmic reticulum stress induces fibrogenic activity in hepatic stellate cells through autophagy | Q36941185 | ||
| The endoplasmic reticulum and the unfolded protein response | Q37006310 | ||
| Mechanisms of protection by the betaine-homocysteine methyltransferase/betaine system in HepG2 cells and primary mouse hepatocytes | Q37097149 | ||
| Endoplasmic reticulum stress is reduced in tissues of obese subjects after weight loss | Q37105351 | ||
| GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice | Q37170811 | ||
| STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease. | Q37236401 | ||
| HIV protease inhibitor lopinavir-induced TNF-alpha and IL-6 expression is coupled to the unfolded protein response and ERK signaling pathways in macrophages | Q37246875 | ||
| Pharmacokinetics of acetaminophen-protein adducts in adults with acetaminophen overdose and acute liver failure | Q37266295 | ||
| P433 | issue | 9 | |
| P921 | main subject | endoplasmic reticulum | Q79927 |
| P304 | page(s) | 1041-1052 | |
| P577 | publication date | 2016-05-03 | |
| P1433 | published in | Expert Review of Gastroenterology & Hepatology | Q15733730 |
| P1476 | title | Targeting endoplasmic reticulum stress in liver disease | |
| P478 | volume | 10 |
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| Q92715111 | Expression of PERK-eIF2α-ATF4 pathway signaling protein in the progression of hepatic fibrosis in rats |
| Q64098634 | Inactivation of Sirtuin2 protects mice from acetaminophen-induced liver injury: possible involvement of ER stress and S6K1 activation |
| Q52338983 | Loss-of-function PCSK9 mutants evade the unfolded protein response sensor, GRP78, and fail to induce endoplasmic reticulum stress when retained. |
| Q54110224 | Oxymatrine Causes Hepatotoxicity by Promoting the Phosphorylation of JNK and Induction of Endoplasmic Reticulum Stress Mediated by ROS in LO2 Cells. |
| Q89771453 | Reversal of deleterious effect of hypertension on the liver by inhibition of endoplasmic reticulum stress |
| Q89848670 | Suppression of IRE1α Attenuated the Fatty Degeneration in Parenteral Nutrition-Related Liver Disease (PNALD) Cell Model |
| Q91364063 | Tumor Microenvironment Regulation by the Endoplasmic Reticulum Stress Transmission Mediator Golgi Protein 73 in Mice |
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