Ursolic acid inhibits the development of nonalcoholic fatty liver disease by attenuating endoplasmic reticulum stress

scientific article

Ursolic acid inhibits the development of nonalcoholic fatty liver disease by attenuating endoplasmic reticulum stress is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1039/C5FO00083A
P698PubMed publication ID25892149

P2093author name stringYu Sun
Ling Zheng
Wen-Jun Wang
Yu-Hao Zhang
Jian-Shuang Li
P2860cites workNutritional related liver disease: targeting the endoplasmic reticulum stressQ37591100
PPAR-α as a key nutritional and environmental sensor for metabolic adaptation.Q37616202
Ursolic acid induces autophagy in U87MG cells via ROS-dependent endoplasmic reticulum stressQ38997751
Palmitic acid induces production of proinflammatory cytokine interleukin-8 from hepatocytesQ40097681
Insulin-mimetic and insulin-sensitizing activities of a pentacyclic triterpenoid insulin receptor activatorQ40187486
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.Q42041480
Oil red-O stains non-adipogenic cells: a precautionary noteQ42326856
Ursolic acid and luteolin-7-glucoside improve lipid profiles and increase liver glycogen content through glycogen synthase kinase-3.Q43175958
Are linear regression techniques appropriate for analysis when the dependent (outcome) variable is not normally distributed?Q45179675
Endoplasmic reticulum stress induces hepatic steatosis via increased expression of the hepatic very low-density lipoprotein receptorQ45200756
Pathology of nonalcoholic steatohepatitisQ46743666
Accumulation of endoplasmic reticulum stress and lipogenesis in the liver through generational effects of high fat diets.Q51543585
Ursolic acid prevents endoplasmic reticulum stress-mediated apoptosis induced by heat stress in mouse cardiac myocytes.Q51761093
ER stress and lipogenesis: a slippery slope toward hepatic steatosis.Q51944768
Inhibition of poly(ADP-ribose) polymerase inhibits ischemia/reperfusion induced neurodegeneration in retina via suppression of endoplasmic reticulum stress.Q54508384
Ursolic acid increases skeletal muscle and brown fat and decreases diet-induced obesity, glucose intolerance and fatty liver diseaseQ21134517
Comparative analysis of gene regulation by the transcription factor PPARalpha between mouse and humanQ21562369
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1Q22011167
Ursolic acid induces ER stress response to activate ASK1-JNK signaling and induce apoptosis in human bladder cancer T24 cellsQ24299207
Roles of CHOP/GADD153 in endoplasmic reticulum stressQ24302185
A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATIONQ25939000
The role of endoplasmic reticulum in hepatic lipid homeostasis and stress signalingQ27008029
Peroxisome proliferator-activated receptor alpha target genesQ28248222
Hepatic steatosis: a role for de novo lipogenesis and the transcription factor SREBP-1cQ28297047
PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiationQ28507769
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
The unfolded protein response: from stress pathway to homeostatic regulationQ29547396
Design and validation of a histological scoring system for nonalcoholic fatty liver diseaseQ29614930
A central role for JNK in obesity and insulin resistanceQ29619778
Long-term follow-up of patients with NAFLD and elevated liver enzymesQ29620024
The Role of PPARα Activation in Liver and MuscleQ34106233
Ursolic acid improves high fat diet-induced cognitive impairments by blocking endoplasmic reticulum stress and IκB kinase β/nuclear factor-κB-mediated inflammatory pathways in mice.Q34195714
Therapeutic role of ursolic acid on ameliorating hepatic steatosis and improving metabolic disorders in high-fat diet-induced non-alcoholic fatty liver disease ratsQ34401755
PPARalpha expression protects male mice from high fat-induced nonalcoholic fatty liverQ34667494
Histone acetyltransferase PCAF regulates inflammatory molecules in the development of renal injuryQ36213039
Mouse models in non-alcoholic fatty liver disease and steatohepatitis research.Q36377266
Mechanisms of hepatic triglyceride accumulation in non-alcoholic fatty liver diseaseQ36788344
The role for endoplasmic reticulum stress in diabetes mellitusQ37019672
Ursolic acid: an anti- and pro-inflammatory triterpenoidQ37059823
GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in miceQ37170811
Molecular mechanisms and the role of saturated fatty acids in the progression of non-alcoholic fatty liver diseaseQ37405640
P433issue5
P921main subjectendoplasmic reticulumQ79927
liver diseaseQ929737
metabolic dysfunction–associated steatotic liver diseaseQ1546498
fatty liver diseaseQ6058862
P1104number of pages9
P304page(s)1643-1651
P577publication date2015-05-01
P1433published inFood & FunctionQ3076426
P1476titleUrsolic acid inhibits the development of nonalcoholic fatty liver disease by attenuating endoplasmic reticulum stress
P478volume6

Reverse relations

cites work (P2860)
Q38588143A comprehensive overview of hepatoprotective natural compounds: mechanism of action and clinical perspectives
Q37719402Abnormal levels of histone methylation in the retinas of diabetic rats are reversed by minocycline treatment
Q90436197Administration of ursolic acid to new-born pups prevents dietary fructose-induced non-alcoholic fatty liver disease in Sprague Dawley rats
Q39450856Anti-hepatocellular carcinoma activity and mechanism of chemopreventive compounds: ursolic acid derivatives
Q92929332Antioxidant and Anti-inflammatory Mechanisms of Neuroprotection by Ursolic Acid: Addressing Brain Injury, Cerebral Ischemia, Cognition Deficit, Anxiety, and Depression
Q48175404Characteristics, Biological Properties and Analytical Methods of Ursolic Acid: A Review
Q38727632Combined Use of Zoledronic Acid Augments Ursolic Acid-Induced Apoptosis in Human Osteosarcoma Cells through Enhanced Oxidative Stress and Autophagy.
Q92256595High Dietary Kuding Tea Extract Supplementation Induces Hepatic Xenobiotic-Metabolizing Enzymes-A 6-Week Feeding Study in Mice
Q38707676Histone HIST1H1C/H1.2 regulates autophagy in the development of diabetic retinopathy
Q28081001Immune Cell Regulatory Pathways Unexplored as Host-Directed Therapeutic Targets for Mycobacterium tuberculosis: An Opportunity to Apply Precision Medicine Innovations to Infectious Diseases
Q42796115MacroH2A1.1 cooperates with EZH2 to promote adipogenesis by regulating Wnt signaling
Q26770555Natural Products for Chemoprevention of Breast Cancer
Q58753073Potential Therapeutic Benefits of Herbs and Supplements in Patients with NAFLD
Q36920683Recent studies on ursolic acid and its biological and pharmacological activity.
Q92533859Salidroside-Mitigated Inflammatory Injury of Hepatocytes with Non-Alcoholic Fatty Liver Disease via Inhibition TRPM2 Ion Channel Activation
Q38811934Targeting endoplasmic reticulum stress in liver disease.
Q38776270The Apoptotic Effect of Ursolic Acid on SK-Hep-1 Cells is Regulated by the PI3K/Akt, p38 and JNK MAPK Signaling Pathways
Q92276485Treatment implications of natural compounds targeting lipid metabolism in nonalcoholic fatty liver disease, obesity and cancer
Q91687570Ursolic Acid Protected Lung of Rats From Damage Induced by Cigarette Smoke Extract

Search more.