Hepatic ZIP14-mediated zinc transport is required for adaptation to endoplasmic reticulum stress

scientific article published on 3 July 2017

Hepatic ZIP14-mediated zinc transport is required for adaptation to endoplasmic reticulum stress is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1073/PNAS.1704012114
P932PMC publication ID5530682
P698PubMed publication ID28673968

P2093author name stringJinhee Kim
Robert J Cousins
Min-Hyun Kim
Tolunay B Aydemir
P2860cites workPTP1B regulates leptin signal transduction in vivoQ24294879
Induction of Grp78/BiP by translational block: activation of the Grp78 promoter by ATF4 through and upstream ATF/CRE site independent of the endoplasmic reticulum stress elementsQ24310021
The oxidative stress: endoplasmic reticulum stress axis in cadmium toxicityQ37687181
Integration of ER stress, oxidative stress and the inflammatory response in health and diseaseQ37724635
Endoplasmic reticulum stress and the on site function of resident PTP1B.Q38011521
The SLC39 family of zinc transporters.Q38090794
Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed miceQ38354947
The Physiological, Biochemical, and Molecular Roles of Zinc Transporters in Zinc Homeostasis and Metabolism.Q38530500
Protective roles of SLC30A3 against endoplasmic reticulum stress via ERK1/2 activation.Q38743441
Rapid, transient induction of ER stress in the liver and kidney after acute exposure to heavy metal: evidence from transgenic sensor miceQ40138182
Two different zinc transport complexes of cation diffusion facilitator proteins localized in the secretory pathway operate to activate alkaline phosphatases in vertebrate cellsQ40402582
Fluoride induces endoplasmic reticulum stress in ameloblasts responsible for dental enamel formationQ40431262
Zinc transporters, ZnT5 and ZnT7, are required for the activation of alkaline phosphatases, zinc-requiring enzymes that are glycosylphosphatidylinositol-anchored to the cytoplasmic membraneQ40496148
Manganese induces endoplasmic reticulum (ER) stress and activates multiple caspases in nigral dopaminergic neuronal cells, SN4741.Q40766780
The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosisQ41904044
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.Q42041480
Liver-specific deletion of protein tyrosine phosphatase (PTP) 1B improves obesity- and pharmacologically induced endoplasmic reticulum stressQ42148009
Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stressQ42451739
ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stressQ42518206
Dietary Zinc Regulates Apoptosis through the Phosphorylated Eukaryotic Initiation Factor 2α/Activating Transcription Factor-4/C/EBP-Homologous Protein Pathway during Pharmacologically Induced Endoplasmic Reticulum Stress in Livers of Mice.Q42724914
Manganese(II) induces apoptotic cell death in NIH3T3 cells via a caspase-12-dependent pathwayQ42816205
Endoplasmic reticulum stress and alteration in calcium homeostasis are involved in cadmium-induced apoptosisQ42827151
SOD1 as a molecular switch for initiating the homeostatic ER stress response under zinc deficiencyQ43631595
Hepatic ZIP14-mediated Zinc Transport Contributes to Endosomal Insulin Receptor Trafficking and Glucose MetabolismQ43869615
Microanalysis of non-heme iron in animal tissuesQ44802778
Activation of ATF6 and an ATF6 DNA binding site by the endoplasmic reticulum stress response.Q45345766
Zinc transport complexes contribute to the homeostatic maintenance of secretory pathway function in vertebrate cellsQ48090774
Accumulation of endoplasmic reticulum stress and lipogenesis in the liver through generational effects of high fat diets.Q51543585
Zinc ions modulate protein tyrosine phosphatase 1B activity.Q54355379
ER stress controls iron metabolism through induction of hepcidinQ24630714
Zinc and the Msc2 zinc transporter protein are required for endoplasmic reticulum function.Q27930535
cAMP-response element (CRE)-mediated transcription by activating transcription factor-4 (ATF4) is essential for circadian expression of the Period2 geneQ28505961
Protein-tyrosine phosphatase 1B potentiates IRE1 signaling during endoplasmic reticulum stressQ28506667
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
Zip14 (Slc39a14) mediates non-transferrin-bound iron uptake into cellsQ28509880
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetesQ28575190
Zinc deficiency mediates alcohol-induced apoptotic cell death in the liver of rats through activating ER and mitochondrial cell death pathwaysQ28581655
Transcription factors Sp1 and Hif2α mediate induction of the copper-transporting ATPase (Atp7a) gene in intestinal epithelial cells during hypoxiaQ28582117
The unfolded protein response: from stress pathway to homeostatic regulationQ29547396
Quality control in the endoplasmic reticulumQ29619929
Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteinsQ33262919
Interleukin-6 regulates the zinc transporter Zip14 in liver and contributes to the hypozincemia of the acute-phase responseQ33784530
The glucose-regulated proteins: stress induction and clinical applicationsQ34336908
Endoplasmic reticulum stress induced by tunicamycin and thapsigargin protects against transient ischemic brain injury: Involvement of PARK2-dependent mitophagyQ34344705
Zinc transporter ZIP14 functions in hepatic zinc, iron and glucose homeostasis during the innate immune response (endotoxemia).Q34461210
Zip14 is a complex broad-scope metal-ion transporter whose functional properties support roles in the cellular uptake of zinc and nontransferrin-bound iron.Q35322005
Toxicogenomics of endoplasmic reticulum stress inducer tunicamycin in the small intestine and liver of Nrf2 knockout and C57BL/6J miceQ35740930
ER stress and the unfolded protein responseQ35986601
Zinc Transporter SLC39A7/ZIP7 Promotes Intestinal Epithelial Self-Renewal by Resolving ER Stress.Q36162478
Zinc transporters and the cellular trafficking of zincQ36468399
Promotion of vesicular zinc efflux by ZIP13 and its implications for spondylocheiro dysplastic Ehlers-Danlos syndrome.Q36485369
ER stress and diseases.Q36731474
High-fat diets: modeling the metabolic disorders of human obesity in rodentsQ36787703
The zinc transporter Zip14 influences c-Met phosphorylation and hepatocyte proliferation during liver regeneration in miceQ36792806
PTP1B as a drug target: recent developments in PTP1B inhibitor discoveryQ36805716
Eukaryotic initiation factor 2 phosphorylation and translational control in metabolism.Q36830383
Transcription factor ATF4 directs basal and stress-induced gene expression in the unfolded protein response and cholesterol metabolism in the liver.Q36849447
Liver-specific deletion of protein-tyrosine phosphatase 1B (PTP1B) improves metabolic syndrome and attenuates diet-induced endoplasmic reticulum stressQ37105304
Zinc transporter Slc39a14 regulates inflammatory signaling associated with hypertrophic adiposityQ37148724
Iron depletion increases manganese uptake and potentiates apoptosis through ER stressQ37164919
From endoplasmic-reticulum stress to the inflammatory responseQ37225354
Targeted overexpression of parathyroid hormone-related peptide in chondrocytes causes chondrodysplasia and delayed endochondral bone formationQ37332979
Mammalian zinc transporters: nutritional and physiologic regulationQ37463198
P4510describes a project that usesImageJQ1659584
P433issue29
P407language of work or nameEnglishQ1860
P921main subjectendoplasmic reticulumQ79927
P304page(s)E5805-E5814
P577publication date2017-07-03
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleHepatic ZIP14-mediated zinc transport is required for adaptation to endoplasmic reticulum stress
P478volume114

Reverse relations

cites work (P2860)
Q49232850Associations between Zinc Deficiency and Metabolic Abnormalities in Patients with Chronic Liver Disease
Q90053613Deletion of metal transporter Zip14 (Slc39a14) produces skeletal muscle wasting, endotoxemia, Mef2c activation and induction of miR-675 and Hspb7
Q92619804Different Actions of Intracellular Zinc Transporters ZIP7 and ZIP13 Are Essential for Dermal Development
Q90448005Endoplasmic reticulum targeting fluorescent probes to image mobile Zn2
Q92932269Increased intestinal permeability exacerbates sepsis through reduced hepatic SCD-1 activity and dysregulated iron recycling
Q57109220Manganese transport and toxicity in polarized WIF-B hepatocytes
Q47784247Recent Advances in the Role of SLC39A/ZIP Zinc Transporters In Vivo
Q92724380Remodeling of Zn2+ homeostasis upon differentiation of mammary epithelial cells
Q64255905Targeting the Zinc Transporter ZIP7 in the Treatment of Insulin Resistance and Type 2 Diabetes
Q51746431The Multiple Faces of the Metal Transporter ZIP14 (SLC39A14).
Q47163079Understanding the Contribution of Zinc Transporters in the Function of the Early Secretory Pathway
Q91874559Zinc as a countermeasure for cadmium toxicity

Search more.