Endoplasmic Reticulum Stress and Related Pathological Processes

scientific article

Endoplasmic Reticulum Stress and Related Pathological Processes is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID3942890
P698PubMed publication ID24611136

P2093author name stringXiaoyong Tong
Richard A Cohen
Yu Mei
Melissa D Thompson
P2860cites workMammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stressQ22010800
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-betaQ22011091
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factorQ24292102
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeatsQ24298956
PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK- and IRE1α-mediated unfolded protein responseQ24301867
Endoplasmic reticulum stress triggers autophagy in malignant glioma cells undergoing cyclosporine a-induced cell deathQ39349204
IRE1beta inhibits chylomicron production by selectively degrading MTP mRNA.Q39422225
The adaptor protein CRK is a pro-apoptotic transducer of endoplasmic reticulum stressQ39426318
The unfolded protein response controls induction and activation of ADAM17/TACE by severe hypoxia and ER stressQ39439223
The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cellsQ39972647
Nitric oxide induces coupling of mitochondrial signalling with the endoplasmic reticulum stress responseQ40500396
Activation of endoplasmic reticulum stress by hyperglycemia is essential for Müller cell-derived inflammatory cytokine production in diabetesQ40666660
Obesity-induced endoplasmic reticulum stress causes chronic inflammation in adipose tissueQ41248481
A role for BiP as an adjustor for the endoplasmic reticulum stress-sensing protein Ire1.Q41854293
The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosisQ41904044
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.Q42041480
Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stressQ42451739
Novel targets for endoplasmic reticulum stress-induced apoptosis in B-CLL.Q42971332
The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophagesQ44542540
S-Glutathiolation by peroxynitrite activates SERCA during arterial relaxation by nitric oxideQ45111036
Neuronal ER stress impedes myeloid-cell-induced vascular regeneration through IRE1α degradation of netrin-1.Q48134071
Modulation of ER stress and apoptosis by endoplasmic reticulum calcium leak via translocon during unfolded protein response: involvement of GRP78.Q52633373
ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation.Q53616050
Monocyte chemotactic protein-induced protein (MCPIP) promotes inflammatory angiogenesis via sequential induction of oxidative stress, endoplasmic reticulum stress and autophagy.Q54495622
Oxygen-dependent ATF-4 stability is mediated by the PHD3 oxygen sensorQ64005208
C/EBP homologous protein deficiency attenuates myocardial reperfusion injury by inhibiting myocardial apoptosis and inflammationQ83433872
Cardioprotection by endoplasmic reticulum stress-induced autophagyQ84778523
Regulation of microRNA expression in the heart by the ATF6 branch of the ER stress responseQ34253691
Viruses, endoplasmic reticulum stress, and interferon responsesQ34482331
Essential role of mitochondrial function in adiponectin synthesis in adipocytesQ34683208
Transmission of endoplasmic reticulum stress and pro-inflammation from tumor cells to myeloid cellsQ34836604
Endoplasmic reticulum stress and insulin resistance post-trauma: similarities to type 2 diabetesQ35552299
The VLDL receptor promotes lipotoxicity and increases mortality in mice following an acute myocardial infarctionQ35572373
Endoplasmic reticulum stress triggers autophagyQ35690087
Roles for endoplasmic reticulum-associated degradation and the novel endoplasmic reticulum stress response gene Derlin-3 in the ischemic heartQ35898986
An IFN-γ-stimulated ATF6-C/EBP-β-signaling pathway critical for the expression of Death Associated Protein Kinase 1 and induction of autophagyQ36068837
ER stress and autophagy: new discoveries in the mechanism of action and drug resistance of the cyclin-dependent kinase inhibitor flavopiridolQ36163061
Protein disulfide isomerase-associated 6 is an ATF6-inducible ER stress response protein that protects cardiac myocytes from ischemia/reperfusion-mediated cell deathQ36176234
Impaired MEK signaling and SERCA expression promote ER stress and apoptosis in insulin-resistant macrophages and are reversed by exenatide treatmentQ36249831
PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stressQ36311137
Death protein 5 and p53-upregulated modulator of apoptosis mediate the endoplasmic reticulum stress-mitochondrial dialog triggering lipotoxic rodent and human β-cell apoptosisQ36339591
ER stress and neurodegenerative diseasesQ36362415
miR-211 is a prosurvival microRNA that regulates chop expression in a PERK-dependent manner.Q36392923
ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growthQ36497999
ER stress potentiates insulin resistance through PERK-mediated FOXO phosphorylationQ36660203
ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death.Q36954378
Antioxidants reduce endoplasmic reticulum stress and improve protein secretionQ36985084
Tribbles 3 mediates endoplasmic reticulum stress-induced insulin resistance in skeletal muscleQ36998996
How IRE1 reacts to ER stressQ37055568
GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in miceQ37170811
From endoplasmic-reticulum stress to the inflammatory responseQ37225354
The endoplasmic reticulum stress response in immunity and autoimmunityQ37231726
The transcription factor ATF4 regulates glucose metabolism in mice through its expression in osteoblastsQ37328439
SR/ER-mitochondrial local communication: calcium and ROS.Q37335548
Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance.Q37339111
Ischemia activates the ATF6 branch of the endoplasmic reticulum stress responseQ37447782
Molecular mechanisms regulating oxidative activity of the Ero1 family in the endoplasmic reticulumQ37756921
Redox signaling loops in the unfolded protein responseQ38000454
ER stress-induced inflammation: does it aid or impede disease progression?Q38033784
Endoplasmic reticulum dysfunction in neurological diseaseQ38067205
Regulation of autophagy by ATF4 in response to severe hypoxia.Q38343634
A thrombospondin-dependent pathway for a protective ER stress responseQ24337738
Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational controlQ24522941
Distinct roles of activating transcription factor 6 (ATF6) and double-stranded RNA-activated protein kinase-like endoplasmic reticulum kinase (PERK) in transcription during the mammalian unfolded protein responseQ24534422
Endoplasmic reticulum stress: cell life and death decisions.Q24536108
Endoplasmic reticulum stress and the inflammatory basis of metabolic diseaseQ24633352
MAM: more than just a housekeeperQ24648220
Immunity, Inflammation, and CancerQ27861048
Dissociation of Kar2p/BiP from an ER sensory molecule, Ire1p, triggers the unfolded protein response in yeastQ28140422
PERK mediates cell-cycle exit during the mammalian unfolded protein responseQ28141519
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNAQ28214814
Endoplasmic reticulum stress induces calcium-dependent permeability transition, mitochondrial outer membrane permeabilization and apoptosisQ28240946
Endoplasmic reticulum stress and atherosclerosisQ28279152
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinaseQ28296183
Regulated translation initiation controls stress-induced gene expression in mammalian cellsQ28506388
PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiationQ28507769
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulumQ28509611
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulumQ28512249
Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox stateQ28572472
XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein ResponseQ28585314
Role of ERO1-alpha-mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress-induced apoptosisQ28586997
The unfolded protein response: from stress pathway to homeostatic regulationQ29547396
Autophagy is activated for cell survival after endoplasmic reticulum stressQ29614485
NF-kappaB functions as a tumour promoter in inflammation-associated cancerQ29614598
The unfolded protein response: controlling cell fate decisions under ER stress and beyondQ29615499
IRE1 signaling affects cell fate during the unfolded protein responseQ29615502
Mammalian endoplasmic reticulum stress sensor IRE1 signals by dynamic clusteringQ30496639
BiP binding to the ER-stress sensor Ire1 tunes the homeostatic behavior of the unfolded protein responseQ33631257
Calcium and ER stress mediate hepatic apoptosis after burn injury.Q33793882
Involvement of endoplasmic reticulum stress in inflammatory bowel disease: a different implication for colonic and ileal disease?Q34058302
Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesityQ34181503
P433issue2
P921main subjectendoplasmic reticulumQ79927
P304page(s)1000107
P577publication date2013-11-01
P1433published inJournal of pharmacological & biomedical analysisQ27725353
P1476titleEndoplasmic Reticulum Stress and Related Pathological Processes
P478volume1

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cites work (P2860)
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Q59336511In vitro culture expansion impairs chondrogenic differentiation and the therapeutic effect of mesenchymal stem cells by regulating the unfolded protein response
Q28390392Inhibition of Eukaryotic Initiation Factor 2 Alpha Phosphatase Reduces Tissue Damage and Improves Learning and Memory after Experimental Traumatic Brain Injury
Q26775037Insulin resistance and hyperinsulinaemia in diabetic cardiomyopathy
Q36085556Interplay between unfolded protein response and autophagy promotes tumor drug resistance
Q59129737Knockdown of KIAA1199 attenuates growth and metastasis of hepatocellular carcinoma
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Q41521286Neuroprotective effects of atorvastatin against cerebral ischemia/reperfusion injury through the inhibition of endoplasmic reticulum stress.
Q90040919Particulate Matter 2.5 Mediates Cutaneous Cellular Injury by Inducing Mitochondria-Associated Endoplasmic Reticulum Stress: Protective Effects of Ginsenoside Rb1
Q55386294Particulate matter 2.5 damages skin cells by inducing oxidative stress, subcellular organelle dysfunction, and apoptosis.
Q35300974Physalis angulata induces in vitro differentiation of murine bone marrow cells into macrophages
Q34603247Sarcoplasmic/endoplasmic reticulum Ca2+ ATPase C674 promotes ischemia- and hypoxia-induced angiogenesis via coordinated endothelial cell and macrophage function
Q89168514Shikonin Exerts Cytotoxic Effects in Human Colon Cancers by Inducing Apoptotic Cell Death via the Endoplasmic Reticulum and Mitochondria-Mediated Pathways
Q34774530Unfolded protein response-regulated Drosophila Fic (dFic) protein reversibly AMPylates BiP chaperone during endoplasmic reticulum homeostasis.
Q36106918miRNA-1283 Regulates the PERK/ATF4 Pathway in Vascular Injury by Targeting ATF4

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