| scholarly article | Q13442814 |
| review article | Q7318358 |
| P50 | author | Brian Popko | Q61009990 |
| P2093 | author name string | Hemamalini Bommiasamy | |
| P2860 | cites work | Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors | Q22008465 |
| Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress | Q22010800 | ||
| XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease | Q22252318 | ||
| ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs | Q24290776 | ||
| Identification of the G13 (cAMP-response-element-binding protein-related protein) gene product related to activating transcription factor 6 as a transcriptional activator of the mammalian unfolded protein response | Q24290935 | ||
| Plasma cell differentiation requires the transcription factor XBP-1 | Q24291453 | ||
| XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor | Q24292102 | ||
| A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells | Q24309442 | ||
| Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha | Q24540258 | ||
| Control of PERK eIF2alpha kinase activity by the endoplasmic reticulum stress-induced molecular chaperone P58IPK. | Q24541469 | ||
| Endoplasmic reticulum stress-induced formation of transcription factor complex ERSF including NF-Y (CBF) and activating transcription factors 6alpha and 6beta that activates the mammalian unfolded protein response | Q24548363 | ||
| XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy | Q24655821 | ||
| IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response | Q24672592 | ||
| The unfolded protein response pathway in Saccharomyces cerevisiae. Oligomerization and trans-phosphorylation of Ire1p (Ern1p) are required for kinase activation | Q27936284 | ||
| Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation | Q28131669 | ||
| Perk is essential for translational regulation and cell survival during the unfolded protein response | Q28140062 | ||
| Translational control is required for the unfolded protein response and in vivo glucose homeostasis | Q28204066 | ||
| IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA | Q28214814 | ||
| Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis | Q28258427 | ||
| Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase | Q28296183 | ||
| Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice | Q28359871 | ||
| The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas | Q28505821 | ||
| Cotranslocational degradation protects the stressed endoplasmic reticulum from protein overload | Q28506232 | ||
| Regulated translation initiation controls stress-induced gene expression in mammalian cells | Q28506388 | ||
| Regulation of hepatic lipogenesis by the transcription factor XBP1 | Q28507784 | ||
| CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum | Q28509611 | ||
| XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands | Q28510479 | ||
| Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha | Q28512201 | ||
| CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum | Q28512249 | ||
| The transcription factor XBP-1 is essential for the development and survival of dendritic cells | Q28512302 | ||
| Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state | Q28572472 | ||
| XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response | Q28585314 | ||
| Role of ERO1-alpha-mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress-induced apoptosis | Q28586997 | ||
| Cloning of mammalian Ire1 reveals diversity in the ER stress responses | Q28587224 | ||
| PERK is essential for neonatal skeletal development to regulate osteoblast proliferation and differentiation. | Q51951390 | ||
| Targeted disruption of the activating transcription factor 4 gene results in severe fetal anemia in mice. | Q52545083 | ||
| Pancreatic beta-cell failure and diabetes in mice with a deletion mutation of the endoplasmic reticulum molecular chaperone gene P58IPK | Q55847305 | ||
| Microphthalmia due to p53-mediated apoptosis of anterior lens epithelial cells in mice lacking the CREB-2 transcription factor | Q73967308 | ||
| Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1 | Q80979487 | ||
| Endoplasmic reticulum stress modulates the response of myelinating oligodendrocytes to the immune cytokine interferon-gamma | Q28591592 | ||
| An essential role in liver development for transcription factor XBP-1 | Q28593777 | ||
| Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival | Q28593963 | ||
| ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response | Q28611502 | ||
| ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals | Q28646129 | ||
| Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response | Q29547299 | ||
| An integrated stress response regulates amino acid metabolism and resistance to oxidative stress | Q29547441 | ||
| IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors | Q29618425 | ||
| The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins | Q29620170 | ||
| Oligomerization and phosphorylation of the Ire1p kinase during intracellular signaling from the endoplasmic reticulum to the nucleus | Q29620179 | ||
| Reduced apoptosis and plaque necrosis in advanced atherosclerotic lesions of Apoe-/- and Ldlr-/- mice lacking CHOP. | Q30488194 | ||
| PERK eIF2 alpha kinase is required to regulate the viability of the exocrine pancreas in mice | Q33295459 | ||
| The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis. | Q33777806 | ||
| P58IPK, a novel endoplasmic reticulum stress-inducible protein and potential negative regulator of eIF2alpha signaling | Q34179244 | ||
| Activation of the ATF6, XBP1 and grp78 genes in human hepatocellular carcinoma: a possible involvement of the ER stress pathway in hepatocarcinogenesis | Q34192744 | ||
| XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation | Q34345459 | ||
| Endoplasmic reticulum stress in disorders of myelinating cells. | Q34962824 | ||
| Perk-dependent translational regulation promotes tumor cell adaptation and angiogenesis in response to hypoxic stress | Q35221396 | ||
| The integrated stress response prevents demyelination by protecting oligodendrocytes against immune-mediated damage | Q35613472 | ||
| The unfolded protein response modulates disease severity in Pelizaeus-Merzbacher disease. | Q36155932 | ||
| XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum. | Q36322684 | ||
| Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis. | Q36393034 | ||
| XBP-1 specifically promotes IgM synthesis and secretion, but is dispensable for degradation of glycoproteins in primary B cells | Q36402768 | ||
| Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153). | Q36561426 | ||
| Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes | Q36861224 | ||
| Enhanced integrated stress response promotes myelinating oligodendrocyte survival in response to interferon-gamma | Q36943108 | ||
| ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth | Q39470144 | ||
| Stress-induced gene expression requires programmed recovery from translational repression | Q39735685 | ||
| Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice | Q39975807 | ||
| In vivo regulation of Grp78/BiP transcription in the embryonic heart: role of the endoplasmic reticulum stress response element and GATA-4. | Q40321831 | ||
| XBP1 is essential for survival under hypoxic conditions and is required for tumor growth. | Q40519913 | ||
| Stress-inducible transcription factor CHOP/gadd153 induces apoptosis in mammalian cells via p38 kinase-dependent and -independent mechanisms | Q40796296 | ||
| Ectopic expression of CHOP (GADD153) induces apoptosis in M1 myeloblastic leukemia cells | Q41157654 | ||
| UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators. | Q42041480 | ||
| Delineation of a negative feedback regulatory loop that controls protein translation during endoplasmic reticulum stress | Q42163338 | ||
| Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stress | Q42451739 | ||
| ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress | Q42518206 | ||
| CHOP (GADD153) and its oncogenic variant, TLS-CHOP, have opposing effects on the induction of G1/S arrest. | Q42801637 | ||
| Ablation of the UPR-mediator CHOP restores motor function and reduces demyelination in Charcot-Marie-Tooth 1B mice | Q43076742 | ||
| The function of GADD34 is a recovery from a shutoff of protein synthesis induced by ER stress: elucidation by GADD34-deficient mice | Q44489907 | ||
| A transgenic mouse model for monitoring endoplasmic reticulum stress | Q44711192 | ||
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 91-109 | |
| P577 | publication date | 2011-01-01 | |
| P1433 | published in | Methods in Enzymology | Q2076903 |
| P1476 | title | Animal models in the study of the unfolded protein response | |
| P478 | volume | 491 |
| Q92637170 | Conflicting Actions of Inhalational Anesthetics, Neurotoxicity and Neuroprotection, Mediated by the Unfolded Protein Response |
| Q46157031 | Membrane lipid saturation activates IRE1α without inducing clustering |
| Q38132652 | Targeting the unfolded protein response in disease. |
| Q29615499 | The unfolded protein response: controlling cell fate decisions under ER stress and beyond |
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