Lack of activation of the unfolded protein response in mouse and cellular models of Niemann-Pick type C disease.

scientific article published on 13 August 2010

Lack of activation of the unfolded protein response in mouse and cellular models of Niemann-Pick type C disease. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1159/000316540
P698PubMed publication ID20714112
P5875ResearchGate publication ID45660404

P50authorANDRES KLEINQ57479591
Matias MosqueiraQ59699541
P2093author name stringClaudio Hetz
Gabriela Martínez
Silvana Zanlungo
Marcela González
Gonzalo I Cancino
Benjamín Caballero
Alejandra R Alvarez
Fermín Robledo
P2860cites workRegulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
Palmitoyl-protein thioesterase-1 deficiency mediates the activation of the unfolded protein response and neuronal apoptosis in INCLQ28589453
Intersection of the unfolded protein response and hepatic lipid metabolismQ34985745
Cholesterol-induced macrophage apoptosis requires ER stress pathways and engagement of the type A scavenger receptorQ36320445
The stress rheostat: an interplay between the unfolded protein response (UPR) and autophagy in neurodegenerationQ37160833
GM1-ganglioside accumulation at the mitochondria-associated ER membranes links ER stress to Ca(2+)-dependent mitochondrial apoptosisQ41970238
Imatinib therapy blocks cerebellar apoptosis and improves neurological symptoms in a mouse model of Niemann-Pick type C diseaseQ46509580
ER and oxidative stresses are common mediators of apoptosis in both neurodegenerative and non-neurodegenerative lysosomal storage disorders and are alleviated by chemical chaperonesQ46910143
U18666A-mediated apoptosis in cultured murine cortical neurons: role of caspases, calpains and kinasesQ46918908
No evidence for activation of the unfolded protein response in neuronopathic models of Gaucher diseaseQ48768126
P433issue3
P304page(s)124-128
P577publication date2010-08-13
P1433published inNeurodegenerative DiseasesQ15764918
P1476titleLack of activation of the unfolded protein response in mouse and cellular models of Niemann-Pick type C disease
P478volume8

Reverse relations

cites work (P2860)
Q40794488ALS-linked protein disulfide isomerase variants cause motor dysfunction
Q46237931Lysosomal and Mitochondrial Liaisons in Niemann-Pick Disease
Q91583666Mitochondrial Cholesterol in Alzheimer's Disease and Niemann-Pick Type C Disease
Q26826845Molecular pathways for intracellular cholesterol accumulation: common pathogenic mechanisms in Niemann-Pick disease Type C and cystic fibrosis
Q28574731Oxidative stress activates the c-Abl/p73 proapoptotic pathway in Niemann-Pick type C neurons
Q28834490The Effect of Small Molecules on Sterol Homeostasis: Measuring 7-Dehydrocholesterol in Dhcr7-Deficient Neuro2a Cells and Human Fibroblasts
Q39097940Unfolded protein response in Gaucher disease: from human to Drosophila
Q48835669Unfolded protein response is not activated in the mucopolysaccharidoses but protein disulfide isomerase 5 is deregulated.

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