Clock genes and clock-controlled genes in the regulation of metabolic rhythms

scientific article published on April 2012

Clock genes and clock-controlled genes in the regulation of metabolic rhythms is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3109/07420528.2012.658127
P698PubMed publication ID22390237
P5875ResearchGate publication ID221887923

P50authorManlio VinciguerraQ37369918
P2093author name stringValerio Pazienza
Gianluigi Mazzoccoli
P2860cites workGenomic convergence among ERRα, PROX1, and BMAL1 in the control of metabolic clock outputsQ21092423
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BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasisQ21146393
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Regulation of clock and NPAS2 DNA binding by the redox state of NAD cofactorsQ24291420
A promoter in the novel exon of hPPARgamma directs the circadian expression of PPARgammaQ24296911
Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesisQ24300249
Rev-erbalpha, a heme sensor that coordinates metabolic and circadian pathwaysQ24300630
Histone acetyltransferase-dependent chromatin remodeling and the vascular clockQ24300792
Cloning of adiponectin receptors that mediate antidiabetic metabolic effectsQ24304889
A molecular mechanism for circadian clock negative feedbackQ24306693
DBC1 is a negative regulator of SIRT1Q24309055
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinaseQ24309462
The nuclear receptor Rev-erbalpha is a liver X receptor (LXR) target gene driving a negative feedback loop on select LXR-induced pathways in human macrophagesQ24317341
SIRT1 regulates circadian clock gene expression through PER2 deacetylationQ24317933
Modulation of retinoic acid receptor-related orphan receptor alpha and gamma activity by 7-oxygenated sterol ligandsQ24336344
Histone lysine demethylase JARID1a activates CLOCK-BMAL1 and influences the circadian clockQ24338936
PGC-1 coactivators: inducible regulators of energy metabolism in health and diseaseQ24541524
Sorting out the roles of PPAR alpha in energy metabolism and vascular homeostasisQ24541529
The circadian regulatory proteins BMAL1 and cryptochromes are substrates of casein kinase IepsilonQ24553966
The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian controlQ24597971
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Obesity and metabolic syndrome in circadian Clock mutant miceQ24627935
Brain and muscle Arnt-like protein-1 (BMAL1), a component of the molecular clock, regulates adipogenesisQ33922817
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Rev-erbalpha upregulates NF-kappaB-responsive genes in vascular smooth muscle cellsQ34304772
Rhythmic expression of DEC1 and DEC2 in peripheral tissues: DEC2 is a potent suppressor for hepatic cytochrome P450s opposing DBP.Q34311213
Melatonin enhances leptin expression by rat adipocytes in the presence of insulin.Q34372413
Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activationQ34416242
Dexamethasone stimulates leptin release from human adipocytes: unexpected inhibition by insulinQ34424728
Bile acid synthesis in humans has a rapid diurnal variation that is asynchronous with cholesterol synthesisQ34467201
ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolismQ34537657
Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expressionQ34563098
Thiol-disulfide redox dependence of heme binding and heme ligand switching in nuclear hormone receptor rev-erb{beta}Q34575796
Nuclear receptors linking circadian rhythms and cardiometabolic control.Q34664996
Circadian rhythm gene period 3 is an inhibitor of the adipocyte cell fate.Q34684926
High-fat diet disrupts behavioral and molecular circadian rhythms in miceQ34710085
PGC-1 coactivators in the control of energy metabolismQ34712077
Proline- and acidic amino acid-rich basic leucine zipper proteins modulate peroxisome proliferator-activated receptor alpha (PPARalpha) activityQ34720504
CLOCK-mediated acetylation of BMAL1 controls circadian functionQ34724581
A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes riskQ34897205
Modulation of the central melanocortin system by leptin, insulin, and serotonin: co-ordinated actions in a dispersed neuronal networkQ34898915
Global co-distribution of light at night (LAN) and cancers of prostate, colon, and lung in men.Q34921279
Intersection of the unfolded protein response and hepatic lipid metabolismQ34985745
Nuclear receptor regulation of genes involved in bile acid metabolismQ34999050
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A web of circadian pacemakersQ35036512
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Altered behavioral and metabolic circadian rhythms in mice with disrupted NAD+ oscillationQ35254830
Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetesQ24633002
Variants in MTNR1B influence fasting glucose levelsQ24642630
Dual modification of BMAL1 by SUMO2/3 and ubiquitin promotes circadian activation of the CLOCK/BMAL1 complexQ24646355
Identification of heme as the ligand for the orphan nuclear receptors REV-ERBalpha and REV-ERBbetaQ24655134
Adverse metabolic and cardiovascular consequences of circadian misalignmentQ24656239
Glucocorticoid regulation of the circadian clock modulates glucose homeostasisQ24657351
Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesisQ24658408
Transducer of regulated CREB-binding proteins (TORCs) induce PGC-1alpha transcription and mitochondrial biogenesis in muscle cellsQ24676703
Diurnal difference in CAR mRNA expressionQ24792012
PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosisQ24798075
Rhythmic expression of Nocturnin mRNA in multiple tissues of the mouseQ24799420
Potential roles of ROR-alpha in cardiovascular endocrinologyQ25255110
Deficient of a clock gene, brain and muscle Arnt-like protein-1 (BMAL1), induces dyslipidemia and ectopic fat formationQ27318655
Feeding cues and injected nutrients induce acute expression of multiple clock genes in the mouse liverQ27323345
Structure of the RXR-RAR DNA-binding complex on the retinoic acid response element DR1Q27621610
The Structural Basis of Gas-Responsive Transcription by the Human Nuclear Hormone Receptor REV-ERBβQ27653944
Activation of PPARgamma coactivator-1 through transcription factor dockingQ28137806
Rotating night shifts and risk of breast cancer in women participating in the nurses' health studyQ28199080
Identification of functional hypoxia response elements in the promoter region of the DEC1 and DEC2 genesQ28204569
SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}Q28235481
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1Q28237795
Circadian regulator CLOCK is a histone acetyltransferaseQ28238584
Circadian transcription of the cholesterol 7 alpha hydroxylase gene may involve the liver-enriched bZIP protein DBPQ28264406
Molecular components of the mammalian circadian clockQ28264527
Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolismQ28266830
Temporal organization: reflections of a Darwinian clock-watcherQ28267753
PGC-1alpha: a key regulator of energy metabolismQ28274239
Is there an association between shift work and having a metabolic syndrome? Results from a population based study of 27,485 peopleQ28361758
Antagonistic role of E4BP4 and PAR proteins in the circadian oscillatory mechanismQ28363498
CLOCK regulates circadian rhythms of hepatic glycogen synthesis through transcriptional activation of Gys2Q28507436
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
Transcriptional coactivator PGC-1alpha integrates the mammalian clock and energy metabolismQ28508765
Vascular PPARgamma controls circadian variation in blood pressure and heart rate through Bmal1Q28508879
An intrinsic gut leptin-melanocortin pathway modulates intestinal microsomal triglyceride transfer protein and lipid absorptionQ33902083
Inflammation and endoplasmic reticulum stress in obesity and diabetesQ33913657
The food-entrainable oscillator: a network of interconnected brain structures entrained by humoral signals?Q37633569
The crosstalk between physiology and circadian clock proteinsQ37661538
The role of clock genes in pharmacologyQ37670214
Chronobiological aspects of food intake and metabolism and their relevance on energy balance and weight regulationQ37685275
Crosstalk between components of circadian and metabolic cycles in mammalsQ37834110
Control of nuclear receptor activities in metabolism by post-translational modificationsQ37864394
Neurobiology of food anticipatory circadian rhythmsQ37869971
Franklin H. Epstein Lecture: Sirtuins, aging, and medicineQ37886170
Chronobiological analysis of circadian patterns in transcription of seven key clock genes in six peripheral tissues in miceQ38296561
Role of adenosine in insulin-stimulated release of leptin from isolated white adipocytes of Wistar ratsQ38316932
Acute physical stress elevates mouse period1 mRNA expression in mouse peripheral tissues via a glucocorticoid-responsive elementQ38319522
Regulation of ob gene expression and leptin secretion by insulin and dexamethasone in rat adipocytesQ38324561
Tissue-dependent alterations of the clock gene expression rhythms in leptin-resistant Zucker diabetic fatty ratsQ38330350
SWItch/sucrose nonfermentable (SWI/SNF) complex subunit BAF60a integrates hepatic circadian clock and energy metabolismQ38333777
Are nuclear receptors involved in pituitary responsiveness to melatonin?Q38352312
Melatonin stimulates glucagon secretion in vitro and in vivoQ39606472
Diurnal regulation of MTP and plasma triglyceride by CLOCK is mediated by SHP.Q39673179
Circadian clock control by SUMOylation of BMAL1.Q40383605
Leptin secretion and negative autocrine crosstalk with insulin in brown adipocytesQ40697480
An intrinsic circadian clock of the pancreas is required for normal insulin release and glucose homeostasis in miceQ41300170
A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolismQ41762089
Circadian control of epigenetic modifications modulates metabolism.Q42185623
Regulation of leptin release by insulin, glucocorticoids, G(i)-coupled receptor agonists, and pertussis toxin in adipocytes and adipose tissue explants from obese humans in primary cultureQ42435613
The circadian PAR-domain basic leucine zipper transcription factors DBP, TEF, and HLF modulate basal and inducible xenobiotic detoxificationQ42497646
Proof-by-synthesis of the transcriptional logic of mammalian circadian clocksQ42808272
Reciprocal regulation of haem biosynthesis and the circadian clock in mammalsQ42827031
Estimation of the benchmark duration of shiftwork associated with weight gain in male Japanese workersQ42850041
Proxisome proliferator-activated receptor-α mediates high-fat, diet-enhanced daily oscillation of plasminogen activator inhibitor-1 activity in miceQ42850059
Effects of light and melatonin treatment on body temperature and melatonin secretion daily rhythms in a diurnal rodent, the fat sand ratQ42925082
Metabolic responses on the early shiftQ42968450
Obesity and high blood pressure of 12-hour night shift female clean-room workersQ43108524
Time-dependent inhibitory effect of lipopolysaccharide injection on Per1 and Per2 gene expression in the mouse heart and liverQ43108527
Circadian clock-coordinated 12 Hr period rhythmic activation of the IRE1alpha pathway controls lipid metabolism in mouse liverQ43194435
Restricted feeding entrains liver clock without participation of the suprachiasmatic nucleusQ43548823
A daily rhythm in glucose tolerance: a role for the suprachiasmatic nucleusQ43618901
Plasma adiponectin levels in overweight and obese AsiansQ44215071
Neuropeptide Y, GABA and circadian phase shifts to photic stimuli.Q44554976
Zeitgeber Hierarchy in Humans: Resetting the Circadian Phase Positions of Blind People Using MelatoninQ44611580
Circadian rhythms: lost in post-translationQ44787628
Persistent twenty-four hour changes in liver and bone marrow despite suprachiasmatic nuclei ablation in mice.Q44951840
Hyperlipidemic effects of dietary saturated fats mediated through PGC-1beta coactivation of SREBP.Q45244060
Hepatic, duodenal, and colonic circadian clocks differ in their persistence under conditions of constant light and in their entrainment by restricted feeding.Q45901975
Temporal gradient in the clock gene and cell-cycle checkpoint kinase Wee1 expression along the gut.Q45914842
Association and evolutionary studies of the melatonin receptor 1B gene (MTNR1B) in the self-contained population of Sorbs from GermanyQ46048864
Casein kinase-1-epsilon (CK1epsilon) and circadian photic responses in hamstersQ46163929
Clock gene expression in peripheral leucocytes of patients with type 2 diabetesQ46272011
Melatonin and the circadian entrainment of metabolic and hormonal activities in primary isolated adipocytes.Q46459035
Free triiodothyronine has a distinct circadian rhythm that is delayed but parallels thyrotropin levelsQ46684102
Nyctohemeral and Sex-Related Variations in Plasma Thyrotropin, Thyroxine, and TriiodothyronineQ46810044
Clock genes display rhythmic expression in human heartsQ47793725
Glutamate immunoreactivity in terminals of the retinohypothalamic tract of the brown Norwegian rat.Q48283092
Crosstalk between environmental light and internal time in humans.Q48291333
Reciprocal regulation of brain and muscle Arnt-like protein 1 and peroxisome proliferator-activated receptor alpha defines a novel positive feedback loop in the rodent liver circadian clock.Q48607003
Circadian variation in basal plasma corticosterone and adrenocorticotropin in the rat: sexual dimorphism and changes across the estrous cycleQ48632395
Dorsal raphe nuclear stimulation of SCN serotonin release and circadian phase-resettingQ48727927
The thalamic intergeniculate leaflet modulates photoperiod responsiveness in Siberian hamstersQ48958631
Pattern of plasma cortisol during the 24-hour sleep/wake cycle in the rhesus monkeyQ49142793
The insulin-melatonin antagonism: studies in the LEW.1AR1-iddm rat (an animal model of human type 1 diabetes mellitus).Q51476122
Dietary obesity caused by a specific circadian eating pattern.Q51483540
Induction of circadian rhythm in cultured human mesenchymal stem cells by serum shock and cAMP analogs in vitro.Q51824955
Evidence for circadian variations in serum thyrotropin, 3,5,3'-triiodothyronine, and thyroxine in the rat.Q52755852
Light induces chromatin modification in cells of the mammalian circadian clock.Q55034441
Characterization of Peripheral Circadian Clocks in Adipose TissuesQ57077990
AMPK regulates the circadian clock by cryptochrome phosphorylation and degradationQ28509385
Nuclear receptor corepressor and histone deacetylase 3 govern circadian metabolic physiologyQ28512844
Regulation of bile acid synthesis by the nuclear receptor Rev-erbalphaQ28585608
Poly(ADP-ribose) polymerase 1 participates in the phase entrainment of circadian clocks to feedingQ28587849
PER2 controls lipid metabolism by direct regulation of PPARγQ28589406
ID2 (inhibitor of DNA binding 2) is a rhythmically expressed transcriptional repressor required for circadian clock output in mouse liverQ28591766
A circadian-regulated gene, Nocturnin, promotes adipogenesis by stimulating PPAR-gamma nuclear translocation.Q28594100
Functional role of AhR in the expression of toxic effects by TCDDQ28609386
Disruption of CLOCK-BMAL1 transcriptional activity is responsible for aryl hydrocarbon receptor-mediated regulation of Period1 geneQ29347268
Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controlsQ29547730
Entrainment of the circadian clock in the liver by feedingQ29615668
The genetics of mammalian circadian order and disorder: implications for physiology and diseaseQ29616366
Metabolic control through the PGC-1 family of transcription coactivatorsQ29616509
Serum immunoreactive-leptin concentrations in normal-weight and obese humansQ29617230
AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolismQ29617261
A transcription factor response element for gene expression during circadian nightQ29617973
A clockwork web: circadian timing in brain and periphery, in health and diseaseQ29618069
Physiological significance of a peripheral tissue circadian clockQ29619075
Circadian gene expression in individual fibroblasts: cell-autonomous and self-sustained oscillators pass time to daughter cellsQ29619080
Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleusQ29619114
Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1Q29619241
Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasisQ29619610
Circadian integration of metabolism and energeticsQ29619638
The meter of metabolismQ29619740
Nuclear receptor expression links the circadian clock to metabolismQ29622820
Nocturnin regulates circadian trafficking of dietary lipid in intestinal enterocytesQ30425427
Loss of Nocturnin, a circadian deadenylase, confers resistance to hepatic steatosis and diet-induced obesityQ30443685
Stomach ghrelin-secreting cells as food-entrainable circadian clocksQ30489507
System-driven and oscillator-dependent circadian transcription in mice with a conditionally active liver clockQ33273610
Effects of nocturnal light on (clock) gene expression in peripheral organs: a role for the autonomic innervation of the liverQ33455489
Regulation of BMAL1 protein stability and circadian function by GSK3beta-mediated phosphorylation.Q33521907
Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in miceQ33604863
Nuclear hormone receptors for heme: REV-ERBalpha and REV-ERBbeta are ligand-regulated components of the mammalian clock.Q33642674
Effect of feeding regimens on circadian rhythms: implications for aging and longevityQ33722180
Circadian rhythms and metabolic syndrome: from experimental genetics to human disease.Q33722806
Circadian clock-coordinated hepatic lipid metabolism: only transcriptional regulation?Q33771982
A wheel of time: the circadian clock, nuclear receptors, and physiologyQ33788478
SirT1 in muscle physiology and disease: lessons from mouse models.Q33815408
Kruppel-like factor KLF10 is a link between the circadian clock and metabolism in liverQ33877614
Unraveling seasonality in population averages: an examination of seasonal variation in glucose levels in diabetes patients using a large population-based data set.Q33888643
Circadian metabolic regulation through crosstalk between casein kinase 1δ and transcriptional coactivator PGC-1α.Q35595707
The mammalian circadian timing system: from gene expression to physiologyQ35874978
Nuclear receptors in macrophage biology: at the crossroads of lipid metabolism and inflammationQ35912822
Leptin and the central nervous system control of glucose metabolismQ36048515
Role of endoplasmic reticulum stress and c-Jun NH2-terminal kinase pathways in inflammation and origin of obesity and diabetesQ36321560
From fat to inflammationQ36364153
Metabolic adaptations through the PGC-1 alpha and SIRT1 pathwaysQ36510743
AMP-activated protein kinase signaling in metabolic regulationQ36528537
SCN outputs and the hypothalamic balance of lifeQ36654635
Circadian rhythms: mechanisms and therapeutic implicationsQ36702128
Circadian rhythms in the development of obesity: potential role for the circadian clock within the adipocyteQ36735641
The orphan nuclear receptor Rev-erbalpha: a transcriptional link between circadian rhythmicity and cardiometabolic diseaseQ36758116
Sirt1 protects against high-fat diet-induced metabolic damageQ36775324
Crosstalk between xenobiotics metabolism and circadian clockQ36798718
Molecular circadian rhythms in central and peripheral clocks in mammals.Q36799431
Circuit projection from suprachiasmatic nucleus to ventral tegmental area: a novel circadian output pathwayQ36829623
Circadian glucose homeostasis requires compensatory interference between brain and liver clocksQ36937004
Minireview: Entrainment of the suprachiasmatic clockwork in diurnal and nocturnal mammals.Q36954065
Genetics of circadian rhythms in Mammalian model organismsQ37005459
Comparing and contrasting the roles of AMPK and SIRT1 in metabolic tissuesQ37024437
Enhanced orexin receptor-2 signaling prevents diet-induced obesity and improves leptin sensitivityQ37071459
Minireview: the PGC-1 coactivator networks: chromatin-remodeling and mitochondrial energy metabolismQ37106839
Sleep-wake regulation is altered in leptin-resistant (db/db) genetically obese and diabetic miceQ37200080
From endoplasmic-reticulum stress to the inflammatory responseQ37225354
Disruption of period gene expression alters the inductive effects of dioxin on the AhR signaling pathway in the mouse liver.Q37263928
Expression profile of mRNAs encoding core circadian regulatory proteins in human subcutaneous adipose tissue: correlation with age and body mass indexQ37346371
Tim-Tipin dysfunction creates an indispensible reliance on the ATR-Chk1 pathway for continued DNA synthesisQ37387886
PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditureQ37412140
Chronobiology, genetics and metabolic syndromeQ37412153
Time of feeding and the intrinsic circadian clock drive rhythms in hepatic gene expressionQ37482097
Molecular control of circadian metabolic rhythmsQ37539497
How nuclear receptors tell time.Q37560481
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)227-251
P577publication date2012-04-01
P1433published inChronobiology InternationalQ2025696
P1476titleClock genes and clock-controlled genes in the regulation of metabolic rhythms
P478volume29

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