review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Bruce Spiegelman | Q21042408 |
P2093 | author name string | Christophe Handschin | |
P433 | issue | 7 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 728-35 | |
P577 | publication date | 2006-12-01 | |
P1433 | published in | Endocrine Reviews | Q3054007 |
P1476 | title | Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism | |
P478 | volume | 27 |
Q36720516 | "Deficiency" of mitochondria in muscle does not cause insulin resistance |
Q36759960 | A Feed-Forward Circuit of Endogenous PGC-1α and Estrogen Related Receptor α Regulates the Neuronal Electron Transport Chain |
Q48099889 | A PGC1β genetic variant associated with nevus count and melanoma mortality. |
Q36691611 | A Role for the PPARgamma in Cancer Therapy. |
Q34517194 | A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance |
Q33915896 | A compendium of human mitochondrial gene expression machinery with links to disease. |
Q34275231 | A greatly extended PPARGC1A genomic locus encodes several new brain-specific isoforms and influences Huntington disease age of onset |
Q35182949 | A peroxisome proliferator-activated receptor gamma (PPARgamma)/PPARgamma coactivator 1beta autoregulatory loop in adipocyte mitochondrial function |
Q46346112 | A potential role for Akt/FOXO signalling in both protein loss and the impairment of muscle carbohydrate oxidation during sepsis in rodent skeletal muscle. |
Q30497916 | A reduction in ATP demand and mitochondrial activity with neural differentiation of human embryonic stem cells. |
Q54416987 | A20 deubiquitinase controls PGC-1α expression in the adipose tissue. |
Q36756228 | AMP-activated protein kinase and its downstream transcriptional pathways |
Q35607865 | AMPD1 regulates mTORC1-p70 S6 kinase axis in the control of insulin sensitivity in skeletal muscle |
Q60921233 | AMPK: a therapeutic target of heart failure-not only metabolism regulation |
Q82468721 | ATF4 regulates lipid metabolism and thermogenesis |
Q33592857 | Aberrant mitochondrial homeostasis in the skeletal muscle of sedentary older adults |
Q36025294 | Abnormal glucose homeostasis in skeletal muscle-specific PGC-1alpha knockout mice reveals skeletal muscle-pancreatic beta cell crosstalk |
Q42070624 | Absence of 4-1BB reduces obesity-induced atrophic response in skeletal muscle. |
Q54653573 | Activation of calcium/calmodulin-dependent protein kinase IV and peroxisome proliferator-activated receptor γ coactivator-1α signaling pathway protects against neuronal injury and promotes mitochondrial biogenesis in the hippocampal CA1 subfield aft |
Q37141585 | Activation of p53 in Down Syndrome and in the Ts65Dn Mouse Brain is Associated with a Pro-Apoptotic Phenotype |
Q41071678 | Activation of peroxisome proliferator activated receptor alpha ameliorates ethanol induced steatohepatitis in mice |
Q98197761 | Acute and chronic effects of resistance training on skeletal muscle markers of mitochondrial remodeling in older adults |
Q46355670 | Adipose Tissue Hypoxia in Obesity and Its Impact on Preadipocytes and Macrophages: Hypoxia Hypothesis |
Q27025566 | Adipose tissues and thyroid hormones |
Q36699616 | Advances and challenges in skeletal muscle angiogenesis |
Q64104462 | Ageing in mice modelling mitochondrial dysfunction induces differential expression of a range of genes regulating ventricular electrophysiology |
Q28386794 | Alternate day fasting impacts the brain insulin-signaling pathway of young adult male C57BL/6 mice |
Q40742156 | Alternate-Day High-Fat Diet Induces an Increase in Mitochondrial Enzyme Activities and Protein Content in Rat Skeletal Muscle |
Q27334070 | Amitriptyline-mediated cognitive enhancement in aged 3×Tg Alzheimer's disease mice is associated with neurogenesis and neurotrophic activity |
Q48513802 | An OLTAM system for analysis of brown/beige fat thermogenic activity |
Q34037337 | An emerging role for bromodomain-containing proteins in chromatin regulation and transcriptional control of adipogenesis |
Q34781822 | Analysis of skeletal muscle gene expression patterns and the impact of functional capacity in patients with systolic heart failure |
Q39977472 | Analyzing phosphorylation-dependent regulation of subcellular localization and transcriptional activity of transcriptional coactivator NT-PGC-1α. |
Q34408010 | Antagonistic functions of LMNA isoforms in energy expenditure and lifespan |
Q47241973 | Anti-hyperglycemic and anti-hyperlipidaemic effect of Arjunarisht in high-fat fed animals. |
Q89138125 | Antifibrotic role of PGC-1α-siRNA against TGF-β1-induced renal interstitial fibrosis |
Q24294870 | Apolipoprotein O is mitochondrial and promotes lipotoxicity in heart |
Q55040672 | Argan oil prevents down-regulation induced by endotoxin on liver fatty acid oxidation and gluconeogenesis and on peroxisome proliferator-activated receptor gamma coactivator-1α, (PGC-1α), peroxisome proliferator-activated receptor α (PPARα) and estr |
Q92282374 | Association of Elite Sports Status with Gene Variants of Peroxisome Proliferator Activated Receptors and Their Transcriptional Coactivator |
Q33906098 | Association of PGC-1alpha polymorphisms with age of onset and risk of Parkinson's disease |
Q50075066 | Association of PGC-1α gene with type 2 diabetes in three unrelated endogamous groups of North-West India (Punjab): a case-control and meta-analysis study |
Q47551144 | Axonal transport in a peripheral diabetic neuropathy model: sex-dimorphic features. |
Q61453698 | BDNF contributes to the skeletal muscle anti-atrophic effect of exercise training through AMPK-PGC1α signaling in heart failure mice |
Q36684324 | Bacterial-excreted small volatile molecule 2-aminoacetophenone induces oxidative stress and apoptosis in murine skeletal muscle |
Q36867507 | Banting Lecture 2012: Regulation of adipogenesis: toward new therapeutics for metabolic disease |
Q34607833 | Bcl3 interacts cooperatively with peroxisome proliferator-activated receptor gamma (PPARgamma) coactivator 1alpha to coactivate nuclear receptors estrogen-related receptor alpha and PPARalpha |
Q42707781 | Beneficial effects of resveratrol on respiratory chain defects in patients' fibroblasts involve estrogen receptor and estrogen-related receptor alpha signaling |
Q33636948 | Bile acid receptor agonist GW4064 regulates PPARγ coactivator-1α expression through estrogen receptor-related receptor α |
Q39143414 | Bioenergetic flux, mitochondrial mass and mitochondrial morphology dynamics in AD and MCI cybrid cell lines |
Q37686246 | Bioenergetic medicine |
Q36155073 | Blockade of the activin receptor IIb activates functional brown adipogenesis and thermogenesis by inducing mitochondrial oxidative metabolism |
Q33642463 | Brd2 disruption in mice causes severe obesity without Type 2 diabetes |
Q34447547 | Brown adipose tissue and thermogenesis |
Q34415748 | Burn trauma in skeletal muscle results in oxidative stress as assessed by in vivo electron paramagnetic resonance. |
Q90718352 | CAIII expression in skeletal muscle is regulated by Ca2+-CaMKII-MEF2C signaling |
Q89314832 | CFTR Deletion Confers Mitochondrial Dysfunction and Disrupts Lipid Homeostasis in Intestinal Epithelial Cells |
Q41885050 | Caloric Restriction and the Nutrient-Sensing PGC-1α in Mitochondrial Homeostasis: New Perspectives in Neurodegeneration |
Q36807218 | Calorie restriction as an intervention in ageing. |
Q35782950 | Can Brown Fat Win the Battle Against White Fat? |
Q36807567 | Cannabinoid type 1 receptor blockade promotes mitochondrial biogenesis through endothelial nitric oxide synthase expression in white adipocytes. |
Q35604967 | Carbohydrate metabolism is perturbed in peroxisome-deficient hepatocytes due to mitochondrial dysfunction, AMP-activated protein kinase (AMPK) activation, and peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) suppression |
Q46768024 | Cardiac Fgf21 synthesis and release: an autocrine loop for boosting up antioxidant defenses in failing hearts |
Q35975055 | Cardiac angiogenic imbalance leads to peripartum cardiomyopathy. |
Q90114942 | Caspase-1 as a regulatory molecule of lipid metabolism |
Q33694606 | Central nervous system melanocortin-3 receptors are required for synchronizing metabolism during entrainment to restricted feeding during the light cycle |
Q41932416 | Changes in mitochondrial function and mitochondria associated protein expression in response to 2-weeks of high intensity interval training |
Q35604515 | Characterization of novel peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) isoform in human liver. |
Q36891685 | Chronic AMPK activation via loss of FLCN induces functional beige adipose tissue through PGC-1α/ERRα. |
Q35672469 | Chronic High Fat Diet Consumption Impairs Metabolic Health of Male Mice |
Q35715576 | Chronic caloric restriction attenuates a loss of sulfatide content in PGC-1α-/- mouse cortex: a potential lipidomic role of PGC-1α in neurodegeneration |
Q34719537 | Chronic inhibition of pyruvate dehydrogenase in heart triggers an adaptive metabolic response |
Q39815780 | Chronology of UPR activation in skeletal muscle adaptations to chronic contractile activity. |
Q37990529 | Clock genes and clock-controlled genes in the regulation of metabolic rhythms |
Q41913082 | Combined speed endurance and endurance exercise amplify the exercise-induced PGC-1α and PDK4 mRNA response in trained human muscle |
Q34133564 | Common variation at PPARGC1A/B and change in body composition and metabolic traits following preventive interventions: the Diabetes Prevention Program |
Q27334737 | Comparative Analysis of Muscle Transcriptome between Pig Genotypes Identifies Genes and Regulatory Mechanisms Associated to Growth, Fatness and Metabolism |
Q64276858 | Comparison of gene expression in cynomolgus monkeys with preclinical type II diabetes induced by different high energy diets |
Q26776167 | Complex Coordination of Cell Plasticity by a PGC-1α-controlled Transcriptional Network in Skeletal Muscle |
Q24305836 | Components of the CCR4-NOT complex function as nuclear hormone receptor coactivators via association with the NRC-interacting Factor NIF-1 |
Q26801402 | Connecting Myokines and Metabolism |
Q51291244 | Control of Secreted Protein Gene Expression and the Mammalian Secretome by the Metabolic Regulator PGC-1α. |
Q36279936 | Control of mitochondrial metabolism and systemic energy homeostasis by microRNAs 378 and 378*. |
Q37323662 | Coordinated Upregulation of Mitochondrial Biogenesis and Autophagy in Breast Cancer Cells: The Role of Dynamin Related Protein-1 and Implication for Breast Cancer Treatment. |
Q46867693 | Correlation between porcine PPARGC1A mRNA expression and its downstream target genes in backfat and longissimus dorsi muscle. |
Q37307474 | Coupling of mitochondrial function and skeletal muscle fiber type by a miR-499/Fnip1/AMPK circuit |
Q37171416 | Cracking the coregulator codes |
Q38747479 | Creatine Prevents the Structural and Functional Damage to Mitochondria in Myogenic, Oxidatively Stressed C2C12 Cells and Restores Their Differentiation Capacity |
Q30571991 | Critical roles of nardilysin in the maintenance of body temperature homoeostasis |
Q97526776 | Current Evidences and Future Perspectives for AMPK in the Regulation of Milk Production and Mammary Gland Biology |
Q35360473 | Cyclin D1 represses gluconeogenesis via inhibition of the transcriptional coactivator PGC1α |
Q90394687 | Cytosolic lipid excess-induced mitochondrial dysfunction is the cause or effect of high fat diet-induced skeletal muscle insulin resistance: a molecular insight |
Q36044757 | Dataset integration identifies transcriptional regulation of microRNA genes by PPARγ in differentiating mouse 3T3-L1 adipocytes |
Q36422633 | Decreased endothelial nitric oxide synthase expression and function contribute to impaired mitochondrial biogenesis and oxidative stress in fetal lambs with persistent pulmonary hypertension |
Q33598357 | Deletion of inducible nitric-oxide synthase in leptin-deficient mice improves brown adipose tissue function |
Q38415182 | Deletion of the metabolic transcriptional coactivator PGC1β induces cardiac arrhythmia |
Q36066429 | Development of insulin resistance in mice lacking PGC-1α in adipose tissues. |
Q62017020 | Development, activation, and therapeutic potential of thermogenic adipocytes |
Q64374695 | Dexamethasone-induced Krüppel-like factor 9 expression promotes hepatic gluconeogenesis and hyperglycemia |
Q33627876 | Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1alpha in skeletal muscle |
Q37300616 | Diet-induced metabolic disturbances as modulators of brain homeostasis |
Q41094641 | Dietary obesity-associated Hif1α activation in adipocytes restricts fatty acid oxidation and energy expenditure via suppression of the Sirt2-NAD+ system. |
Q99709051 | Differences in the Loin Tenderness of Iberian Pigs Explained through Dissimilarities in Their Transcriptome Expression Profile |
Q92311935 | Differences in the fast muscle methylome provide insight into sex-specific epigenetic regulation of growth in Nile tilapia during early stages of domestication |
Q35955181 | Differential gene expression in human abdominal aortic aneurysm and aortic occlusive disease |
Q28583037 | Differential regulation of PGC-1alpha expression in rat liver and skeletal muscle in response to voluntary running |
Q34811695 | Differential regulation of human ALAS1 mRNA and protein levels by heme and cobalt protoporphyrin |
Q33640312 | Differential regulation of the PGC family of genes in a mouse model of Staphylococcus aureus sepsis |
Q47095014 | Dihydrosanguinarine Enhances Glucose Uptake in Mouse 3T3-L1 Cells |
Q36207472 | Direct link between metabolic regulation and the heat-shock response through the transcriptional regulator PGC-1α. |
Q37724195 | Discovery and development of selective PPAR gamma modulators as safe and effective antidiabetic agents. |
Q28593294 | Disruption of BCATm in mice leads to increased energy expenditure associated with the activation of a futile protein turnover cycle |
Q42074582 | Divergent transcriptional activities determine limb identity |
Q52650963 | Diverse roles of mitochondria in ischemic stroke. |
Q37732609 | Does IRISIN Have a BRITE Future as a Therapeutic Agent in Humans? |
Q44965473 | Does eating less make you live longer and better? An update on calorie restriction |
Q37296820 | Dorsomedial hypothalamic NPY modulation of adiposity and thermogenesis |
Q37084823 | Down-regulation of cardiac lineage protein (CLP-1) expression in CLP-1 +/- mice affords |
Q37549613 | Downregulation of PGC-1α Prevents the Beneficial Effect of EET-Heme Oxygenase-1 on Mitochondrial Integrity and Associated Metabolic Function in Obese Mice |
Q50471158 | Downregulation of Pgc-1α expression by tea leaves and their by-products. |
Q33803444 | Dynamic, M2-like remodeling phenotypes of CD11c+ adipose tissue macrophages during high-fat diet--induced obesity in mice |
Q89686441 | Dysregulated metabolic pathways in age-related macular degeneration |
Q37263563 | ERRalpha: a metabolic function for the oldest orphan |
Q90118178 | Effect of VCP modulators on gene expression profiles of retinal ganglion cells in an acute injury mouse model |
Q36535716 | Effect of co-exposure to nickel and particulate matter on insulin resistance and mitochondrial dysfunction in a mouse model |
Q40847479 | Effect of denervation on the regulation of mitochondrial transcription factor A expression in skeletal muscle |
Q43763115 | Effect of moderate dietary restriction on visceral organ weight, hepatic oxygen consumption, and metabolic proteins associated with energy balance in mature pregnant beef cows |
Q40086742 | Effects of dietary phosphate on glucose and lipid metabolism |
Q92533188 | Effects of obesity and weight loss on mitochondrial structure and function and implications for colorectal cancer risk |
Q28534558 | Effects of resveratrol and SIRT1 on PGC-1α activity and mitochondrial biogenesis: a reevaluation |
Q47133846 | Effects of trimetazidine on mitochondrial respiratory function, biosynthesis, and fission/fusion in rats with acute myocardial ischemia |
Q33598389 | Electric pulse stimulation of cultured murine muscle cells reproduces gene expression changes of trained mouse muscle |
Q36263721 | Electroacupuncture Upregulates SIRT1-Dependent PGC-1α Expression in SAMP8 Mice |
Q24621162 | Elevated expression of the metabolic regulator receptor-interacting protein 140 results in cardiac hypertrophy and impaired cardiac function |
Q30480487 | Elucidation of separate, but collaborative functions of the rRNA methyltransferase-related human mitochondrial transcription factors B1 and B2 in mitochondrial biogenesis reveals new insight into maternally inherited deafness |
Q33877188 | Emerging functional similarities and divergences between Drosophila Spargel/dPGC-1 and mammalian PGC-1 protein |
Q37661237 | Emerging role of neuregulin as a modulator of muscle metabolism |
Q58724065 | Emerging roles of long non-coding RNAs in tumor metabolism |
Q90396446 | Endurance exercise increases the protein levels of PGC-1α and respiratory chain complexes in mouse skeletal muscle during atorvastatin administration |
Q34559786 | Energy metabolic reprogramming in the hypertrophied and early stage failing heart: a multisystems approach |
Q35600126 | Enhanced differentiation of three-gene-reprogrammed induced pluripotent stem cells into adipocytes via adenoviral-mediated PGC-1α overexpression |
Q39753180 | Estrogen-related receptor alpha and PGC-1-related coactivator constitute a novel complex mediating the biogenesis of functional mitochondria |
Q34629911 | Estrogen-related receptor alpha modulates lactate dehydrogenase activity in thyroid tumors |
Q42917811 | Estrogens repress PGC1-α expression in the uterus |
Q55410665 | Evidence that S6K1, but not 4E-BP1, mediates skeletal muscle pathology associated with loss of A-type lamins. |
Q34979613 | Exercise ameliorates high-fat diet-induced metabolic and vascular dysfunction, and increases adipocyte progenitor cell population in brown adipose tissue |
Q37157213 | Exercise training and peripheral arterial disease |
Q42467489 | Exercise-induced immunosuppression: roles of reactive oxygen species and 5'-AMP-activated protein kinase dephosphorylation within immune cells. |
Q35211637 | Expression of key regulators of mitochondrial biogenesis in growth hormone receptor knockout (GHRKO) mice is enhanced but is not further improved by other potential life-extending interventions. |
Q34223682 | Expression of mitochondrial regulators PGC1α and TFAM as putative markers of subtype and chemoresistance in epithelial ovarian carcinoma |
Q34156903 | Extracellular signal-regulated kinase 8 (ERK8) controls estrogen-related receptor α (ERRα) cellular localization and inhibits its transcriptional activity. |
Q36682672 | Extract of Wax Gourd Peel Prevents High-Fat Diet-Induced Hyperlipidemia in C57BL/6 Mice via the Inhibition of the PPARγ Pathway |
Q35060670 | Extracts of Rhizoma polygonati odorati prevent high-fat diet-induced metabolic disorders in C57BL/6 mice |
Q42789527 | FGF15/19 regulates hepatic glucose metabolism by inhibiting the CREB-PGC-1α pathway |
Q24653481 | FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response |
Q42034608 | FGF21 mediates the lipid metabolism response to amino acid starvation. |
Q37023028 | Fat partitioning and insulin sensitivity: robbing Peter to pay Paul? |
Q37116706 | Features of an altered AMPK metabolic pathway in Gilbert's Syndrome, and its role in metabolic health |
Q36720494 | Fetal PGC-1α overexpression programs adult pancreatic β-cell dysfunction |
Q33778251 | Fiber type conversion by PGC-1α activates lysosomal and autophagosomal biogenesis in both unaffected and Pompe skeletal muscle |
Q90550690 | Fibroblast growth factor 21 induces lipolysis more efficiently than it suppresses lipogenesis in goat adipocytes |
Q49630025 | Fibroblast growth factor 21 inhibition aggravates cardiac dysfunction in diabetic cardiomyopathy by improving lipid accumulation |
Q39881165 | Fibroblast growth factor-19, a novel factor that inhibits hepatic fatty acid synthesis |
Q35537540 | Fibroblast growth factor-21 enhances mitochondrial functions and increases the activity of PGC-1α in human dopaminergic neurons via Sirtuin-1. |
Q57790481 | Fischer rats exhibit maladaptive structural and molecular right ventricular remodelling in severe pulmonary hypertension: a genetically prone model for right heart failure |
Q44769887 | Fragmentation studies of SIRT1-activating drugs and their detection in human plasma for doping control purposes |
Q38259591 | From pathways to targets: understanding the mechanisms behind polyglutamine disease. |
Q93081283 | Fucoidan Suppresses Mitochondrial Dysfunction and Cell Death against 1-Methyl-4-Phenylpyridinum-Induced Neuronal Cytotoxicity via Regulation of PGC-1α Expression |
Q37223281 | Functional genomic analysis of frataxin deficiency reveals tissue-specific alterations and identifies the PPARgamma pathway as a therapeutic target in Friedreich's ataxia |
Q36849190 | G Protein-Coupled Bile Acid Receptor TGR5 Activation Inhibits Kidney Disease in Obesity and Diabetes |
Q35925797 | G Protein-coupled Receptor 40 (GPR40) and Peroxisome Proliferator-activated Receptor γ (PPARγ): AN INTEGRATED TWO-RECEPTOR SIGNALING PATHWAY. |
Q35096744 | Gene expression changes in aging zebrafish (Danio rerio) brains are sexually dimorphic. |
Q35568088 | Genetic Associations of PPARGC1A with Type 2 Diabetes: Differences among Populations with African Origins |
Q90716283 | Genetic deficiency or pharmacological inhibition of miR-33 protects from kidney fibrosis |
Q34274193 | Genome-wide linkage analysis of QTL for growth and body composition employing the PorcineSNP60 BeadChip |
Q33637458 | Genomic and non-genomic regulation of PGC1 isoforms by estrogen to increase cerebral vascular mitochondrial biogenesis and reactive oxygen species protection |
Q36212575 | Gestational ethanol exposure alters the behavioral response to ethanol odor and the expression of neurotransmission genes in the olfactory bulb of adolescent rats |
Q38941228 | Glutathione and mitochondria determine acute defense responses and adaptive processes in cadmium-induced oxidative stress and toxicity of the kidney |
Q42652649 | Gpbar1 agonism promotes a Pgc-1α-dependent browning of white adipose tissue and energy expenditure and reverses diet-induced steatohepatitis in mice. |
Q55073658 | Grape seed proanthocyanidin extracts ameliorate podocyte injury by activating peroxisome proliferator-activated receptor-γ coactivator 1α in low-dose streptozotocin-and high-carbohydrate/high-fat diet-induced diabetic rats. |
Q46024728 | Haploinsufficiency of the retinoblastoma protein gene reduces diet-induced obesity, insulin resistance, and hepatosteatosis in mice. |
Q37449771 | Heme oxygenase and carbon monoxide protect from muscle dystrophy |
Q34265010 | Hepatic SRC-1 activity orchestrates transcriptional circuitries of amino acid pathways with potential relevance for human metabolic pathogenesis |
Q37833669 | Hepatocyte metabolic signalling pathways and regulation of hepatitis B virus expression |
Q40020653 | High molecular weight adiponectin inhibits proliferation of hepatic stellate cells via activation of adenosine monophosphate-activated protein kinase |
Q43016333 | High-intensity interval training increases SIRT1 activity in human skeletal muscle |
Q37605918 | Histone modifications and skeletal muscle metabolic gene expression. |
Q37540634 | Homeostatic theory of obesity |
Q92685663 | Hydrogen gas therapy induced shrinkage of metastatic gallbladder cancer: A case report |
Q35142716 | IHG-1 promotes mitochondrial biogenesis by stabilizing PGC-1α. |
Q39293674 | IL-15 Mediates Mitochondrial Activity through a PPARδ-Dependent-PPARα-Independent Mechanism in Skeletal Muscle Cells. |
Q58780301 | Identification of a Bromodomain-containing Protein 2 Gene Polymorphic Variant and Its Effects on Pork Quality Traits in Berkshire Pigs |
Q48232880 | Identification of differentially expressed genes and pathways for intramuscular fat metabolism between breast and thigh tissues of chickens |
Q34465132 | Identification of new differentially methylated genes that have potential functional consequences in prostate cancer |
Q37619653 | Idiopathic chronic fatigue in older adults is linked to impaired mitochondrial content and biogenesis signaling in skeletal muscle |
Q40630534 | Impact of caloric restriction on myocardial ischaemia/reperfusion injury and new therapeutic options to mimic its effects |
Q36379783 | Impaired calcium calmodulin kinase signaling and muscle adaptation response in the absence of calpain 3 |
Q45715937 | Impaired mitochondrial function and reduced viability in bone marrow cells of obese mice |
Q84987787 | Impaired mitochondrial respiration and decreased fatigue resistance followed by severe muscle weakness in skeletal muscle of mitochondrial DNA mutator mice |
Q35578632 | Improvement Characteristics of Bio-active Materials Coated Fabric on Rat Muscular Mitochondria |
Q35089820 | In vivo correction of COX deficiency by activation of the AMPK/PGC-1α axis |
Q35616315 | Inactivation of EWS reduces PGC-1α protein stability and mitochondrial homeostasis |
Q36022397 | Increased Cord Blood Betatrophin Levels in the Offspring of Mothers with Gestational Diabetes |
Q37019164 | Increased expression of estrogen-related receptor β during adaptation of adult cardiomyocytes to sustained hypoxia |
Q42476920 | Increased fatigue resistance linked to Ca2+-stimulated mitochondrial biogenesis in muscle fibres of cold-acclimated mice |
Q38661692 | Increased sensitivity of thyroid hormone-mediated signaling despite prolonged fasting |
Q36226760 | Inhibition of Adhesion Molecule Gene Expression and Cell Adhesion by the Metabolic Regulator PGC-1α |
Q88721042 | Inhibition of protein arginine methyltransferase 5 enhances hepatic mitochondrial biogenesis |
Q99238100 | Insight on Transcriptional Regulation of the Energy Sensing AMPK and Biosynthetic mTOR Pathway Genes |
Q37689883 | Insulin and Insulin-Sensitizing Drugs in Neurodegeneration: Mitochondria as Therapeutic Targets |
Q35783723 | Insulin-like growth factor 1 alleviates high-fat diet-induced myocardial contractile dysfunction: role of insulin signaling and mitochondrial function |
Q40808661 | Integration of the nuclear receptor REV-ERBα linked with circadian oscillators in the expressions of Alas1, Ppargc1a, and Il6 genes in rat granulosa cells. |
Q44318860 | Interaction between maternal and postnatal high fat diet leads to a greater risk of myocardial dysfunction in offspring via enhanced lipotoxicity, IRS-1 serine phosphorylation and mitochondrial defects |
Q38794698 | Interaction effect of PGC-1α rs10517030 variants and energy intake in the risk of type 2 diabetes in middle-aged adults |
Q48685804 | Interaction of estrogen receptor-alpha ligand binding domain with nuclear proteins of aging mouse brain |
Q36739504 | Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle |
Q34020532 | Intersection between metabolic dysfunction, high fat diet consumption, and brain aging. |
Q48335155 | Involvement of PKCα and ERK1/2 signaling pathways in EGCG's protection against stress-induced neural injuries in Wistar rats |
Q58569441 | Irisin alleviates liver ischemia-reperfusion injury by inhibiting excessive mitochondrial fission, promoting mitochondrial biogenesis and decreasing oxidative stress |
Q92823826 | Irisin as a Multifunctional Protein: Implications for Health and Certain Diseases |
Q36131728 | Isoform-specific SCF(Fbw7) ubiquitination mediates differential regulation of PGC-1α. |
Q36928810 | Key regulators of mitochondrial biogenesis are increased in kidneys of growth hormone receptor knockout (GHRKO) mice |
Q34976793 | Knockdown of NPY expression in the dorsomedial hypothalamus promotes development of brown adipocytes and prevents diet-induced obesity |
Q30424438 | Kruppel-like factor 15 regulates skeletal muscle lipid flux and exercise adaptation. |
Q36870559 | LPS decreases fatty acid oxidation and nuclear hormone receptors in the kidney |
Q33556492 | Leucine deprivation decreases fat mass by stimulation of lipolysis in white adipose tissue and upregulation of uncoupling protein 1 (UCP1) in brown adipose tissue |
Q35193150 | Leucine deprivation stimulates fat loss via increasing CRH expression in the hypothalamus and activating the sympathetic nervous system |
Q34308013 | Linking epigenetics to lipid metabolism: focus on histone deacetylases. |
Q33314702 | Liver X receptor alpha is a transcriptional repressor of the uncoupling protein 1 gene and the brown fat phenotype. |
Q38734694 | Long noncoding RNA Tug1 regulates mitochondrial bioenergetics in diabetic nephropathy |
Q33805159 | Longissimus dorsi transcriptome analysis of purebred and crossbred Iberian pigs differing in muscle characteristics. |
Q28290989 | Low-intensity exercise enhances expression of markers of alternative activation in circulating leukocytes: Roles of PPARγ and Th2 cytokines |
Q41881288 | MAPK phosphatase-1 facilitates the loss of oxidative myofibers associated with obesity in mice |
Q49491716 | MH84 improves mitochondrial dysfunction in a mouse model of early Alzheimer's disease |
Q40154119 | MH84: A Novel γ-Secretase Modulator/PPARγ Agonist--Improves Mitochondrial Dysfunction in a Cellular Model of Alzheimer's Disease |
Q37717928 | MYC and mitochondrial biogenesis |
Q36083076 | Macrophage Mitochondrial Energy Status Regulates Cholesterol Efflux and Is Enhanced by Anti-miR33 in Atherosclerosis |
Q24304151 | Mammalian ste20-like kinase and SAV1 promote 3T3-L1 adipocyte differentiation by activation of PPARγ |
Q53205630 | Mangiferin Protects Retinal Ganglion Cells in Ischemic Mouse Retina via SIRT1. |
Q46569842 | Mass spectrometric studies on the in vitro generated metabolites of SIRT1 activating drugs for doping control purposes |
Q38111704 | Mechanisms of exercise-induced mitochondrial biogenesis in skeletal muscle: implications for health and disease. |
Q37597600 | Mechanisms of obesity and related pathologies: transcriptional control of adipose tissue development |
Q50975047 | Mechanistic Role of Kinases in the Regulation of Mitochondrial Fitness. |
Q21284811 | Melanoma: from melanocyte to genetic alterations and clinical options |
Q91646512 | Metabolic Remodelling: An Accomplice for New Therapeutic Strategies to Fight Lung Cancer |
Q27687459 | Metabolic benefits of resistance training and fast glycolytic skeletal muscle |
Q92131583 | Metabolic flux analyses to assess the differentiation of adult cardiac progenitors after fatty acid supplementation |
Q37776434 | Metabolic manipulators: a well founded strategy to combat mitochondrial dysfunction |
Q38354303 | Methods for assessing and modulating UCP2 expression and function. |
Q91994662 | MiR-30b-5p regulates the lipid metabolism by targeting PPARGC1A in Huh-7 cell line |
Q36117409 | Mice lacking δ-opioid receptors resist the development of diet-induced obesity |
Q38703571 | MicroRNA-211 Regulates Oxidative Phosphorylation and Energy Metabolism in Human Vitiligo |
Q35513839 | Microarray analysis suggests that burn injury results in mitochondrial dysfunction in human skeletal muscle |
Q28084780 | Minireview: nuclear receptor coregulators of the p160 family: insights into inflammation and metabolism |
Q33634287 | Minireview: the SRC family of coactivators: an entrée to understanding a subset of polygenic diseases? |
Q38671017 | Mitochondria and Reactive Oxygen Species Contribute to Neurogenic Hypertension |
Q55619121 | Mitochondria as a potential regulator of myogenesis. |
Q38809996 | Mitochondria in Acute Kidney Injury |
Q90260807 | Mitochondria in the Pulmonary Vasculature in Health and Disease: Oxygen-Sensing, Metabolism, and Dynamics |
Q38453882 | Mitochondria, muscle health, and exercise with advancing age. |
Q21563343 | Mitochondrial 2,4-dienoyl-CoA reductase deficiency in mice results in severe hypoglycemia with stress intolerance and unimpaired ketogenesis |
Q41633018 | Mitochondrial DNA copy number is reduced in male combat veterans with PTSD. |
Q36235955 | Mitochondrial DNA mutations distinguish bilateral multifocal renal oncocytomas from familial Birt-Hogg-Dubé tumors |
Q35893619 | Mitochondrial Diseases Part III: Therapeutic interventions in mouse models of OXPHOS deficiencies |
Q39016389 | Mitochondrial Dysfunction and Biogenesis in Neurodegenerative diseases: Pathogenesis and Treatment. |
Q64943955 | Mitochondrial Genetic Disorders: Cell Signaling and Pharmacological Therapies. |
Q38189524 | Mitochondrial alteration in type 2 diabetes and obesity: an epigenetic link. |
Q36472242 | Mitochondrial biogenesis in epithelial cancer cells promotes breast cancer tumor growth and confers autophagy resistance |
Q28387647 | Mitochondrial dysfunction in neurodegenerative diseases |
Q37460232 | Mitochondrial energy metabolism and redox signaling in brain aging and neurodegeneration |
Q38228592 | Mitochondrial function and mitochondrial DNA maintenance with advancing age. |
Q38570535 | Mitochondrial function in ageing: coordination with signalling and transcriptional pathways |
Q38303584 | Mitochondrial homeostasis molecules: regulation by a trio of recessive Parkinson's disease genes |
Q98467122 | Mitochondrial metabolism and cancer metastasis |
Q34096931 | Mitochondrial respiration and respiration-associated proteins in cell lines created through Parkinson's subject mitochondrial transfer |
Q38536293 | Mitochondrial responsibility in ageing process: innocent, suspect or guilty |
Q36751888 | Mitochondrial sirtuins and metabolic homeostasis |
Q41660993 | Mitochondrial-Targeted Antioxidant Maintains Blood Flow, Mitochondrial Function, and Redox Balance in Old Mice Following Prolonged Limb Ischemia |
Q34313858 | Mitogen-activated protein kinase phosphatase-1 – a potential therapeutic target in metabolic disease |
Q38765948 | Mitonuclear communication in homeostasis and stress |
Q43073839 | Modular evolution of PGC-1alpha in vertebrates |
Q24305080 | Modulation of clock gene expression by the transcriptional coregulator receptor interacting protein 140 (RIP140) |
Q33575523 | Modulation of microglial innate immunity in Alzheimer's disease by activation of peroxisome proliferator-activated receptor gamma |
Q90362634 | Molecular Characterization of PGC-1β (PPAR Gamma Coactivator 1β) and its Roles in Mitochondrial Biogenesis in Blunt Snout Bream (Megalobrama amblycephala) |
Q61810316 | Molecular Characterization of Peroxisome Proliferator-Activated Receptor-Gamma Coactivator-1α (PGC1α) and Its Role in Mitochondrial Biogenesis in Blunt Snout Bream () |
Q37347216 | Molecular aspects of β, β-carotene-9', 10'-oxygenase 2 in carotenoid metabolism and diseases |
Q35884861 | Molecular mechanisms for age-associated mitochondrial deficiency in skeletal muscle. |
Q36405916 | Molecular pathways: the metabolic regulator estrogen-related receptor α as a therapeutic target in cancer |
Q37329666 | Multi-modulation of nuclear receptor coactivators through posttranslational modifications |
Q35780719 | Multiparity leads to obesity and inflammation in mothers and obesity in male offspring |
Q24309467 | Multiple binding modes between HNF4alpha and the LXXLL motifs of PGC-1alpha lead to full activation |
Q35916696 | Muscle transcriptome response to ACTH administration in a free-ranging marine mammal |
Q89944650 | Mutant p53-Associated Molecular Mechanisms of ROS Regulation in Cancer Cells |
Q89070225 | Mutations in the SWI/SNF complex induce a targetable dependence on oxidative phosphorylation in lung cancer |
Q55334122 | NADPH Oxidases and Mitochondria in Vascular Senescence. |
Q34232057 | NCoR1 is a conserved physiological modulator of muscle mass and oxidative function |
Q58697824 | Natural Molecules From Chinese Herbs Protecting Against Parkinson's Disease via Anti-oxidative Stress |
Q96304531 | Natural products, PGC-1 α , and Duchenne muscular dystrophy |
Q27865238 | Negative feedback maintenance of heme homeostasis by its receptor, Rev-erbalpha |
Q34110994 | Negative regulators of brown adipose tissue (BAT)-mediated thermogenesis |
Q39459539 | Neuronal Ca2+ sensor-1 contributes to stress tolerance in cardiomyocytes via activation of mitochondrial detoxification pathways. |
Q38685353 | New insights into the trophic and cytoprotective effects of creatine in in vitro and in vivo models of cell maturation |
Q61763828 | Next generation sequencing of RNA reveals novel targets of resveratrol with possible implications for Canavan disease |
Q34373713 | Nicotinamide improves motor deficits and upregulates PGC-1α and BDNF gene expression in a mouse model of Huntington's disease |
Q61811713 | Nicotinamide riboside regulates inflammation and mitochondrial markers in AML12 hepatocytes |
Q38197690 | Non-alcoholic fatty liver disease: the role of nuclear receptors and circadian rhythmicity. |
Q37220566 | Non-crystalline and crystalline rheumatic disorders in chronic kidney disease |
Q37215280 | Novel Polymorphisms of Adrenergic, Alpha-1B-, Receptor and Peroxisome Proliferator-activated Receptor Gamma, Coactivator 1 Beta Genes and Their Association with Egg Production Traits in Local Chinese Dagu Hens |
Q28582239 | Novel small-molecule PGC-1α transcriptional regulator with beneficial effects on diabetic db/db mice |
Q33783615 | Nuclear control of respiratory chain expression by nuclear respiratory factors and PGC-1-related coactivator |
Q36585576 | Nuclear respiratory factor 1 controls myocyte enhancer factor 2A transcription to provide a mechanism for coordinate expression of respiratory chain subunits |
Q36533623 | OXPHOS mutations and neurodegeneration |
Q42091923 | Obesity increases vascular senescence and susceptibility to ischemic injury through chronic activation of Akt and mTOR. |
Q26828559 | Obesity pharmacotherapy: current perspectives and future directions |
Q46324842 | Overexpression of PGC-1α increases peroxisomal activity and mitochondrial fatty acid oxidation in human primary myotubes. |
Q37667638 | Oxidative Priority, Meal Frequency, and the Energy Economy of Food and Activity: Implications for Longevity, Obesity, and Cardiometabolic Disease. |
Q37036247 | Oxidative stress and transcriptional regulation in Alzheimer disease |
Q39600000 | PGC-1 alpha regulates HO-1 expression, mitochondrial dynamics and biogenesis: Role of epoxyeicosatrienoic acid |
Q34314784 | PGC-1 coactivators regulate MITF and the tanning response. |
Q36585564 | PGC-1-related coactivator complexes with HCF-1 and NRF-2beta in mediating NRF-2(GABP)-dependent respiratory gene expression |
Q45208517 | PGC-1alpha attenuates neointimal formation via inhibition of vascular smooth muscle cell migration in the injured rat carotid artery |
Q33552305 | PGC-1alpha down-regulation affects the antioxidant response in Friedreich's ataxia |
Q46560150 | PGC-1alpha increases skeletal muscle lactate uptake by increasing the expression of MCT1 but not MCT2 or MCT4. |
Q33564184 | PGC-1alpha negatively regulates hepatic FGF21 expression by modulating the heme/Rev-Erb(alpha) axis |
Q28588689 | PGC-1alpha regulates a HIF2alpha-dependent switch in skeletal muscle fiber types |
Q35720854 | PGC-1alpha regulates the neuromuscular junction program and ameliorates Duchenne muscular dystrophy. |
Q30431199 | PGC-1alpha regulation by exercise training and its influences on muscle function and insulin sensitivity |
Q37485965 | PGC-1alpha-induced improvements in skeletal muscle metabolism and insulin sensitivity |
Q37299286 | PGC-1alpha-mediated regulation of gene expression and metabolism: implications for nutrition and exercise prescriptions |
Q37292951 | PGC-1alpha/beta induced expression partially compensates for respiratory chain defects in cells from patients with mitochondrial disorders. |
Q24643920 | PGC-1alpha/beta upregulation is associated with improved oxidative phosphorylation in cells harboring nonsense mtDNA mutations |
Q28583359 | PGC-1{alpha} and PGC-1{beta} regulate mitochondrial density in neurons |
Q64072545 | PGC-1α Controls Mitochondrial Biogenesis in Drug-Resistant Colorectal Cancer Cells by Regulating Endoplasmic Reticulum Stress |
Q36676999 | PGC-1α Induces Human RPE Oxidative Metabolism and Antioxidant Capacity |
Q35758752 | PGC-1α Promoter Methylation in Parkinson's Disease |
Q48019115 | PGC-1α Protects from Notch-Induced Kidney Fibrosis Development |
Q94445507 | PGC-1α activator ZLN005 promotes maturation of cardiomyocytes derived from human embryonic stem cells |
Q49981669 | PGC-1α ameliorates kidney fibrosis in mice with diabetic kidney disease through an antioxidative mechanism |
Q34163451 | PGC-1α determines light damage susceptibility of the murine retina |
Q36477221 | PGC-1α improves glucose homeostasis in skeletal muscle in an activity-dependent manner. |
Q86038384 | PGC-1α mediates a rapid, exercise-induced downregulation of glycogenolysis in rat skeletal muscle |
Q30574513 | PGC-1α overexpression exacerbates β-amyloid and tau deposition in a transgenic mouse model of Alzheimer's disease |
Q36185112 | PGC-1α overexpression suppresses blood pressure elevation in DOCA-salt hypertensive mice |
Q90667596 | PGC-1α plays a pivotal role in simvastatin-induced exercise impairment in mice |
Q35370349 | PGC-1α promotes recovery after acute kidney injury during systemic inflammation in mice |
Q36511504 | PGC-1α regulates normal and pathological angiogenesis in the retina |
Q34258952 | PGC-1α supports glutamine metabolism in breast cancer. |
Q27001671 | PGC-1α, mitochondrial dysfunction, and Huntington's disease |
Q38017137 | PGC-1α: a master gene that is hard to master |
Q37173344 | PGC-1β and ChREBP partner to cooperatively regulate hepatic lipogenesis in a glucose concentration-dependent manner |
Q35744002 | PGC-1β regulates angiogenesis in skeletal muscle. |
Q51368714 | PGC1α gene Gly482Ser polymorphism predicts improved metabolic, inflammatory and vascular outcomes following bariatric surgery. |
Q28584186 | PPAR-gamma coactivator-1alpha regulates progesterone production in ovarian granulosa cells with SF-1 and LRH-1 |
Q47388274 | PPAR-α agonist elicits metabolically active brown adipocytes and weight loss in diet-induced obese mice |
Q47959840 | PPARGC1A is upregulated and facilitates lung cancer metastasis |
Q36846578 | PPARGC1A variation associated with DNA damage, diabetes, and cardiovascular diseases: the Boston Puerto Rican Health Study. |
Q44994548 | PPARgamma agonist pioglitazone does not enhance performance in mice. |
Q37215869 | PPARgamma agonists as therapeutics for the treatment of Alzheimer's disease |
Q36798663 | PPARgamma and Proline Oxidase in Cancer |
Q41828567 | PPARs and Adipose Cell Plasticity |
Q38285171 | PPARs and ERRs: molecular mediators of mitochondrial metabolism |
Q42164574 | PPAR{delta} agonism activates fatty acid oxidation via PGC-1{alpha} but does not increase mitochondrial gene expression and function |
Q47903151 | PPARβ Is Essential for Maintaining Normal Levels of PGC-1α and Mitochondria and for the Increase in Muscle Mitochondria Induced by Exercise |
Q93063267 | PU-91 drug rescues human age-related macular degeneration RPE cells; implications for AMD therapeutics |
Q38704475 | Palmitate-induced Regulation of PPARγ via PGC1α: a Mechanism for Lipid Accumulation in the Liver in Nonalcoholic Fatty Liver Disease |
Q37427457 | Passive and post-exercise cold-water immersion augments PGC-1α and VEGF expression in human skeletal muscle. |
Q48189776 | Peroxisome Proliferator-Activated Receptors Associated with Nonalcoholic Fatty Liver Disease. |
Q37834354 | Peroxisome proliferator activated receptor-alpha (PPARα) and PPAR gamma coactivator-1alpha (PGC-1α) regulation of cardiac metabolism in diabetes |
Q41144730 | Peroxisome proliferator activated receptor-γ and the ubiquitin-proteasome system in colorectal cancer |
Q38344199 | Peroxisome proliferator-activated receptor gamma co-activator 1alpha (PGC-1alpha) and sirtuin 1 (SIRT1) reside in mitochondria: possible direct function in mitochondrial biogenesis |
Q32179190 | Peroxisome proliferator-activated receptor gamma coactivator-1 alpha acts as a tumor suppressor in hepatocellular carcinoma |
Q34236724 | Peroxisome proliferator-activated receptor {gamma} coactivator 1{alpha} (PGC-1{alpha}) promotes skeletal muscle lipid refueling in vivo by activating de novo lipogenesis and the pentose phosphate pathway. |
Q24307610 | Peroxisome proliferator-activated receptor γ coactivator 1 (PGC-1)- and estrogen-related receptor (ERR)-induced regulator in muscle 1 (Perm1) is a tissue-specific regulator of oxidative capacity in skeletal muscle cells |
Q41913346 | Peroxisome proliferator-activated receptor-gamma coactivator-1alpha controls transcription of the Sirt3 gene, an essential component of the thermogenic brown adipocyte phenotype. |
Q37577955 | Peroxisome proliferator-activated receptor-gamma coactivator-1alpha in muscle links metabolism to inflammation |
Q40132769 | Peroxisome proliferator-activated receptor-γ coactivator-1α mediates neuroprotection against excitotoxic brain injury in transgenic mice: role of mitochondria and X-linked inhibitor of apoptosis protein. |
Q36853131 | Peroxisome proliferator-activated-γ coactivator-1α-mediated mitochondrial biogenesis is important for hematopoietic recovery in response to stress |
Q38357539 | Peroxisome-mitochondria interplay and disease. |
Q34473733 | Pgc-1α overexpression downregulates Pitx3 and increases susceptibility to MPTP toxicity associated with decreased Bdnf |
Q37497833 | Pharmacological approaches to restore mitochondrial function |
Q39635280 | Phosphatidylinositol 3‐kinase affects mitochondrial function in part through inducing peroxisome proliferator‐activated receptor γ coactivator‐1β expression |
Q41333306 | Placental DNA methylation of peroxisome-proliferator-activated receptor-γ co-activator-1α promoter is associated with maternal gestational glucose level |
Q41181654 | Plantago asiatica L. Seed Extract Improves Lipid Accumulation and Hyperglycemia in High-Fat Diet-Induced Obese Mice |
Q37616522 | Polar bears exhibit genome-wide signatures of bioenergetic adaptation to life in the arctic environment |
Q88417234 | Principles of Exercise Prescription, and How They Influence Exercise-Induced Changes of Transcription Factors and Other Regulators of Mitochondrial Biogenesis |
Q27302085 | Prolactin receptor signaling is essential for perinatal brown adipocyte function: a role for insulin-like growth factor-2 |
Q37736468 | Proline metabolism and microenvironmental stress |
Q91644474 | Prospective of managing impaired brain insulin signalling in late onset Alzheimers disease with excisting diabetic drugs |
Q36014621 | Protection from Metabolic Dysregulation, Obesity, and Atherosclerosis by Citrus Flavonoids: Activation of Hepatic PGC1α-Mediated Fatty Acid Oxidation |
Q28546800 | Protective effects of myricetin on acute hypoxia-induced exercise intolerance and mitochondrial impairments in rats |
Q38350241 | Protective effects of peroxisome proliferator-activated receptors gamma coactivator-1alpha against neuronal cell death in the hippocampal CA1 subfield after transient global ischemia. |
Q37138702 | Proteomic changes associated with diabetes in the BB-DP rat. |
Q37610171 | Proteomic profiling of mitochondria: what does it tell us about the ageing brain? |
Q37036533 | RETRACTED: Activation of the PPAR/PGC-1alpha pathway prevents a bioenergetic deficit and effectively improves a mitochondrial myopathy phenotype |
Q36453536 | Rb intrinsically promotes erythropoiesis by coupling cell cycle exit with mitochondrial biogenesis |
Q80240567 | Really different knockout strains in movement? |
Q38546045 | Recent progress in studies on the health benefits of pyrroloquinoline quinone. |
Q30429165 | Recombinant human mitochondrial transcription factor A stimulates mitochondrial biogenesis and ATP synthesis, improves motor function after MPTP, reduces oxidative stress and increases survival after endotoxin |
Q36181511 | Reconsidering the Role of Mitochondria in Aging |
Q26849213 | Redox regulation of mitochondrial biogenesis |
Q35123509 | Reduction in reactive oxygen species production by mitochondria from elderly subjects with normal and impaired glucose tolerance |
Q38998393 | Regulation of Carbohydrate Metabolism, Lipid Metabolism, and Protein Metabolism by AMPK. |
Q33885372 | Regulation of NT-PGC-1alpha subcellular localization and function by protein kinase A-dependent modulation of nuclear export by CRM1. |
Q37726321 | Regulation of metabolism by nuclear hormone receptors |
Q30363035 | Regulation of obesity and insulin resistance by nitric oxide |
Q37697191 | Regulation of skeletal muscle cell plasticity by the peroxisome proliferator-activated receptor γ coactivator 1α. |
Q52804608 | Relation of nNOS isoforms to mitochondrial density and PGC-1alpha expression in striated muscles of mice. |
Q34958919 | Relaxin activates peroxisome proliferator-activated receptor γ (PPARγ) through a pathway involving PPARγ coactivator 1α (PGC1α) |
Q26748160 | Resveratrol and Myopathy |
Q95841476 | Review on the Role of Epigenetic Modifications in Doxorubicin-Induced Cardiotoxicity |
Q41447101 | Ribosomal transcription is regulated by PGC-1alpha and disturbed in Huntington's disease |
Q35958359 | Role and treatment of mitochondrial DNA-related mitochondrial dysfunction in sporadic neurodegenerative diseases |
Q34262223 | Role of interleukin 10 transcriptional regulation in inflammation and autoimmune disease |
Q27028142 | Role of mitochondria in nonalcoholic fatty liver disease |
Q37581203 | Role of peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) in denervation-induced atrophy in aged muscle: facts and hypotheses |
Q34364833 | Role of the mixed-lineage protein kinase pathway in the metabolic stress response to obesity |
Q35536106 | Roles of oxidative stress, apoptosis, PGC-1α and mitochondrial biogenesis in cerebral ischemia. |
Q26824141 | Running forward: new frontiers in endurance exercise biology |
Q24677035 | SCFCdc4 acts antagonistically to the PGC-1alpha transcriptional coactivator by targeting it for ubiquitin-mediated proteolysis |
Q37372145 | SIRT1 controls the transcription of the peroxisome proliferator-activated receptor-gamma Co-activator-1alpha (PGC-1alpha) gene in skeletal muscle through the PGC-1alpha autoregulatory loop and interaction with MyoD. |
Q37625383 | SIRT1-dependent regulation of chromatin and transcription: linking NAD(+) metabolism and signaling to the control of cellular functions |
Q64938925 | Saturated Fatty Acid-Enriched Diet-Impaired Mitochondrial Bioenergetics in Liver From Undernourished Rats During Critical Periods of Development. |
Q37236343 | Sensitivity of lipid metabolism and insulin signaling to genetic alterations in hepatic peroxisome proliferator-activated receptor-gamma coactivator-1alpha expression |
Q37121804 | Sestrin2 Silencing Exacerbates Cerebral Ischemia/Reperfusion Injury by Decreasing Mitochondrial Biogenesis through the AMPK/PGC-1α Pathway in Rats |
Q47554940 | Sestrin2 prevents age-related intolerance to post myocardial infarction via AMPK/PGC-1α pathway |
Q37068084 | Short hairpin RNA-mediated silencing of PRC (PGC-1-related coactivator) results in a severe respiratory chain deficiency associated with the proliferation of aberrant mitochondria |
Q35045136 | Signaling in muscle contraction |
Q99562765 | Simvastatin Impairs Glucose Homeostasis in Mice Depending on PGC-1α Skeletal Muscle Expression |
Q37710177 | Sirtuins and Their Roles in Brain Aging and Neurodegenerative Disorders |
Q34699239 | Sirtuins as novel players in the pathogenesis of diabetes mellitus |
Q26828939 | Sirtuins as regulators of metabolism and healthspan |
Q36925258 | Skeletal muscle SIRT1 and the genetics of metabolic health: therapeutic activation by pharmaceuticals and exercise |
Q35779124 | Skeletal muscle transcriptional coactivator PGC-1α mediates mitochondrial, but not metabolic, changes during calorie restriction |
Q34102995 | Skeletal muscle-specific expression of PGC-1α-b, an exercise-responsive isoform, increases exercise capacity and peak oxygen uptake |
Q33417863 | Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo |
Q24317356 | Structural activity relationship of flavonoids with estrogen-related receptor gamma |
Q38764046 | Structural correlates of the creatine transporter function regulation: the undiscovered country |
Q36322590 | Successful aging: Advancing the science of physical independence in older adults. |
Q37581782 | Sustained kidney biochemical derangement in treated experimental diabetes: a clue to metabolic memory. |
Q52931257 | Systematic analysis of circadian genes using genome-wide cDNA microarrays in the inflammatory bowel disease transcriptome. |
Q92431868 | THE PPARGC1A - GLY482SER POLYMORPHISM (RS8192678) AND THE METABOLIC SYNDROME IN A CENTRAL ROMANIAN POPULATION |
Q28586703 | TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis |
Q34412057 | Targeting mitochondrial alterations to prevent type 2 diabetes--evidence from studies of dietary redox-active compounds |
Q37353401 | Taurine promotes cognitive function in prenatally stressed juvenile rats via activating the Akt-CREB-PGC1α pathway |
Q38769589 | Tauroursodeoxycholic Acid Enhances Mitochondrial Biogenesis, Neural Stem Cell Pool, and Early Neurogenesis in Adult Rats |
Q43289311 | Temporal and spatial patterns of gene expression in skeletal muscles in response to swim training in adult zebrafish (Danio rerio). |
Q34447429 | The "Skinny" on brown fat, obesity, and bone |
Q54945060 | The CD36-PPARγ Pathway in Metabolic Disorders. |
Q45833603 | The Combination of Physical Exercise with Muscle-Directed Antioxidants to Counteract Sarcopenia: A Biomedical Rationale for Pleiotropic Treatment with Creatine and Coenzyme Q10. |
Q37043646 | The Effects of High Fat Diet and Resveratrol on Mitochondrial Activity of Brown Adipocytes |
Q93025892 | The Expression of CNS-Specific PPARGC1A Transcripts Is Regulated by Hypoxia and a Variable GT Repeat Polymorphism |
Q37146493 | The Genomic Context and Corecruitment of SP1 Affect ERRα Coactivation by PGC-1α in Muscle Cells. |
Q64067029 | The PGC-1/ERR network and its role in precision oncology |
Q38064784 | The PGC-1/ERR signaling axis in cancer |
Q37156948 | The PPAR trio: regulators of myocardial energy metabolism in health and disease |
Q96304680 | The Pan-Sirtuin Inhibitor MC2494 Regulates Mitochondrial Function in a Leukemia Cell Line |
Q52722809 | The Role of Peroxisome Proliferator-Activated Receptor γ Coactivator 1α (PGC-1α) in Kidney Disease. |
Q34332654 | The Warburg effect in tumor progression: mitochondrial oxidative metabolism as an anti-metastasis mechanism |
Q54560082 | The circadian clock influences heart performance. |
Q36027410 | The combination of Artemisia princeps Pamp, Leonurus japonicas Houtt, and Gardenia jasminoides Ellis fruit attenuates the exacerbation of energy, lipid, and glucose by increasing hepatic PGC-1α expression in estrogen-deficient rats |
Q36433751 | The coordination of nuclear and mitochondrial communication during aging and calorie restriction |
Q36240784 | The impact of aging on mitochondrial function and biogenesis pathways in skeletal muscle of sedentary high- and low-functioning elderly individuals |
Q36931760 | The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity |
Q33680529 | The influences of parental diet and vitamin E intake on the embryonic zebrafish transcriptome. |
Q28577820 | The inhibitory effect of dexamethasone on platelet-derived growth factor-induced vascular smooth muscle cell migration through up-regulating PGC-1α expression |
Q36976447 | The interplay of prolactin and the glucocorticoids in the regulation of beta-cell gene expression, fatty acid oxidation, and glucose-stimulated insulin secretion: implications for carbohydrate metabolism in pregnancy |
Q64242188 | The metabolic modulator PGC-1α in cancer |
Q43081561 | The molecular basis of aerobic metabolic remodeling differs between oxidative muscle and liver of threespine sticklebacks in response to cold acclimation |
Q42497788 | The protective role of peroxisome proliferator-activated receptor γ coactivator-1α in hyperthyroid cardiac hypertrophy |
Q33840188 | The role of PGC-1 coactivators in aging skeletal muscle and heart |
Q36984669 | The role of exercise and PGC1alpha in inflammation and chronic disease |
Q46063109 | The transcriptional cascade associated with creatine kinase down-regulation and mitochondrial biogenesis in mice sarcoma. |
Q37482064 | The transcriptional coactivator PGC-1alpha mediates exercise-induced angiogenesis in skeletal muscle |
Q38693949 | Thyroid hormone-stimulated increases in PGC-1α and UCP2 promote life history-specific endocrine changes and maintain a lipid-based metabolism |
Q30429437 | Total Skeletal Muscle PGC-1 Deficiency Uncouples Mitochondrial Derangements from Fiber Type Determination and Insulin Sensitivity |
Q36198477 | Transcription Factor Tfe3 Directly Regulates Pgc-1alpha in Muscle |
Q45303085 | Transcription meets metabolism in neurodegeneration |
Q64088994 | Transcriptional Regulation of Ovarian Steroidogenic Genes: Recent Findings Obtained from Stem Cell-Derived Steroidogenic Cells |
Q40339336 | Transcriptional activators enhance polyadenylation of mRNA precursors. |
Q39905162 | Transcriptional co-activator peroxisome proliferator-activated receptor (PPAR)gamma co-activator-1beta is involved in the regulation of glucose-stimulated insulin secretion in INS-1E cells. |
Q34796354 | Transcriptional coactivators PGC-1alpha and PGC-lbeta control overlapping programs required for perinatal maturation of the heart |
Q37429465 | Transcriptional control of brown adipocyte development and physiological function--of mice and men. |
Q35923008 | Transcriptional control of cardiac fuel metabolism and mitochondrial function |
Q37977719 | Transcriptional control of mitochondrial biogenesis and its interface with inflammatory processes |
Q26998468 | Transcriptional integration of mitochondrial biogenesis |
Q34056556 | Transcriptional network analysis in muscle reveals AP-1 as a partner of PGC-1α in the regulation of the hypoxic gene program |
Q38385739 | Transcriptional regulatory circuits controlling muscle fiber type switching. |
Q21559705 | Transcriptomic analyses of sexual dimorphism of the zebrafish liver and the effect of sex hormones |
Q48062088 | Transcriptomic and metabolic analyses reveal salvage pathways in creatine-deficient AGAT(-/-) mice. |
Q35268092 | Truncated peroxisome proliferator-activated receptor-γ coactivator 1α splice variant is severely altered in Huntington's disease |
Q34131460 | Ubiquitin proteasome-dependent degradation of the transcriptional coactivator PGC-1{alpha} via the N-terminal pathway |
Q45063363 | Ultrastructure of Skeletal Muscles in Mice Lacking Muscle-Specific VEGF Expression. |
Q27314765 | Unexpected novel relational links uncovered by extensive developmental profiling of nuclear receptor expression |
Q27300795 | Up-regulation of mitochondrial activity and acquirement of brown adipose tissue-like property in the white adipose tissue of fsp27 deficient mice |
Q90481623 | Upregulation of neuronal PGC-1α ameliorates cognitive impairment induced by chronic cerebral hypoperfusion |
Q47913074 | VLDL and apolipoprotein CIII induce ER stress and inflammation and attenuate insulin signalling via Toll-like receptor 2 in mouse skeletal muscle cells. |
Q42730688 | What is "Hyper" in the ALS Hypermetabolism? |
Q37162234 | Whole body overexpression of PGC-1alpha has opposite effects on hepatic and muscle insulin sensitivity |
Q58732794 | Yiqihuoxue decoction protects against post-myocardial infarction injury via activation of cardiomyocytes PGC-1α expression |
Q44970152 | Zinc enhances the cellular energy supply to improve cell motility and restore impaired energetic metabolism in a toxic environment induced by OTA. |
Q85250124 | [Brown, white, beige: the color of fat and new therapeutic perspectives for obesity...]. |
Q39256910 | mTORC1 signaling in hepatic lipid metabolism |
Q51186779 | miR-148a and miR-17-5p synergistically regulate milk TAG synthesis via PPARGC1A and PPARA in goat mammary epithelial cells. |
Q55002919 | p53 and metabolism: from mechanism to therapeutics. |
Q36479544 | p53 orchestrates the PGC-1α-mediated antioxidant response upon mild redox and metabolic imbalance |
Q28568738 | β-Adrenergic stimulation does not activate p38 MAP kinase or induce PGC-1α in skeletal muscle |
Q33596037 | β-Aminoisobutyric acid induces browning of white fat and hepatic β-oxidation and is inversely correlated with cardiometabolic risk factors |
Q37635065 | β-Carotene-9',10'-oxygenase status modulates the impact of dietary tomato and lycopene on hepatic nuclear receptor-, stress-, and metabolism-related gene expression in mice |
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