Rb intrinsically promotes erythropoiesis by coupling cell cycle exit with mitochondrial biogenesis

scientific article

Rb intrinsically promotes erythropoiesis by coupling cell cycle exit with mitochondrial biogenesis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1101/GAD.1627208
P932PMC publication ID2238668
P698PubMed publication ID18258751
P5875ResearchGate publication ID5592980

P50authorCarl R WalkleyQ41175729
P2093author name stringStuart H Orkin
Vijay G Sankaran
P2860cites workGene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and woundsQ21146433
ABC-me: a novel mitochondrial transporter induced by GATA-1 during erythroid differentiationQ22254182
Premature ageing in mice expressing defective mitochondrial DNA polymeraseQ24294365
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profilesQ24536351
Cyclin D1 repression of nuclear respiratory factor 1 integrates nuclear DNA synthesis and mitochondrial functionQ24554383
Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolismQ28266830
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alphaQ28274682
Global regulation of erythroid gene expression by transcription factor GATA-1Q28275891
A common set of gene regulatory networks links metabolism and growth inhibitionQ28291530
Mitochondrial lesions in reversible erythropoietic depression due to chloramphenicolQ28363082
Retinoblastoma promotes definitive erythropoiesis by repressing Id2 in fetal liver macrophagesQ28507476
Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entryQ28509466
Mitoferrin is essential for erythroid iron assimilationQ28587125
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetesQ29547229
Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementationQ29614475
Inducible gene targeting in miceQ29614544
Effects of an Rb mutation in the mouseQ29619196
Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesisQ29619200
Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenanceQ29620462
Phase II multicenter study of arsenic trioxide in patients with myelodysplastic syndromesQ33371058
Clinical response of myelodysplastic syndromes patients to treatment with coenzyme Q10.Q33373088
Control of globin gene expression during development and erythroid differentiationQ33645104
Sox6 cell-autonomously stimulates erythroid cell survival, proliferation, and terminal maturation and is thereby an important enhancer of definitive erythropoiesis during mouse developmentQ33995222
Ineffective erythropoiesis in Stat5a(-/-)5b(-/-) mice due to decreased survival of early erythroblastsQ34102833
The retinoblastoma tumour suppressor in development and cancerQ34161991
Pearson's marrow-pancreas syndrome. A multisystem mitochondrial disorder in infancyQ34263470
A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient miceQ34381923
Cell-nonautonomous function of the retinoblastoma tumour suppressor protein: new interpretations of old phenotypesQ34526004
Influence of cell cycle phase-specific agents on simian fetal hemoglobin synthesisQ34630922
Rb is dispensable for self-renewal and multilineage differentiation of adult hematopoietic stem cellsQ34657898
Cyclin D1 determines mitochondrial function in vivoQ35070938
GATA-1-mediated proliferation arrest during erythroid maturation.Q35107812
Transcriptional regulatory circuits controlling mitochondrial biogenesis and functionQ35683727
Development of mice expressing a single D-type cyclin.Q35805563
The Rb tumor suppressor in stress responses and hematopoietic homeostasisQ35990252
Myelodysplastic syndromes: the complexity of stem-cell diseasesQ36717910
Gene silencing by DNA methylation in haematological malignanciesQ36816162
The Rb tumor suppressor is required for stress erythropoiesis.Q37592846
Extensive contribution of Rb-deficient cells to adult chimeric mice with limited histopathological consequencesQ37636172
Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiationQ38313575
Unbiased location analysis of E2F1-binding sites suggests a widespread role for E2F1 in the human genomeQ38314358
Identification of target genes of the p16INK4A-pRB-E2F pathway.Q38351396
Mitochondrial biogenesis in mammals: the role of endogenous nitric oxide.Q38357891
The Ets transcription factor GABP is required for cell-cycle progressionQ40174673
Cell-intrinsic requirement for pRb in erythropoiesisQ40553705
Developmental rescue of an embryonic-lethal mutation in the retinoblastoma gene in chimeric miceQ40793159
Rb regulates interactions between hematopoietic stem cells and their bone marrow microenvironmentQ41883433
Rb is critical in a mammalian tissue stem cell populationQ42088436
Extra-embryonic function of Rb is essential for embryonic development and viabilityQ44329398
Requirement for a functional Rb-1 gene in murine developmentQ44462954
Role of Ras signaling in erythroid differentiation of mouse fetal liver cells: functional analysis by a flow cytometry-based novel culture systemQ44542236
Conditional gene targeting in macrophages and granulocytes using LysMcre mice.Q44554898
A mouse model for visualization and conditional mutations in the erythroid lineageQ44848170
Loss of Hspa9b in zebrafish recapitulates the ineffective hematopoiesis of the myelodysplastic syndromeQ45223679
Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.Q45302702
Pathogenic mitochondrial DNA-induced respiration defects in hematopoietic cells result in anemia by suppressing erythroid differentiationQ48202720
Distinct roles of Mdm2 and Mdm4 in red cell productionQ49069222
Hematopoietic stem cells expressing the myeloid lysozyme gene retain long-term, multilineage repopulation potential.Q51014847
An intrinsic but cell-nonautonomous defect in GATA-1-overexpressing mouse erythroid cellsQ59058678
Narrowing and genomic annotation of the commonly deleted region of the 5q- syndromeQ63248769
Three stages of erythropoietic progenitor cell differentiation distinguished by a number of physical and biologic propertiesQ67263236
Human marrow cells capable of erythropoietic differentiation in vitro: definition of three erythroid colony responsesQ67574088
Generation of mice with mitochondrial dysfunction by introducing mouse mtDNA carrying a deletion into zygotesQ73035349
Retinoblastoma gene deficiency has mitogenic but not tumorigenic effects on erythropoiesisQ73722671
Myelodysplastic syndromesQ78556827
Arsenic trioxide in patients with myelodysplastic syndromes: a phase II multicenter studyQ83229175
P433issue4
P304page(s)463-475
P577publication date2008-02-07
P1433published inGenes & DevelopmentQ1524533
P1476titleRb intrinsically promotes erythropoiesis by coupling cell cycle exit with mitochondrial biogenesis
P478volume22