Peroxisome proliferator-activated receptor-γ coactivator-1α mediates neuroprotection against excitotoxic brain injury in transgenic mice: role of mitochondria and X-linked inhibitor of apoptosis protein.

scientific article published on 6 January 2016

Peroxisome proliferator-activated receptor-γ coactivator-1α mediates neuroprotection against excitotoxic brain injury in transgenic mice: role of mitochondria and X-linked inhibitor of apoptosis protein. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/EJN.13157
P698PubMed publication ID26741810
P5875ResearchGate publication ID289537150

P50authorMarc BaumannQ38591097
Valentina Di LibertoQ47363607
Maciej LalowskiQ54447380
Lauri M LouhivuoriQ61150547
Giuseppa MudòQ89849561
Laura KorhonenQ91533410
Natale BelluardoQ91683023
Dan LindholmQ114437839
P2093author name stringOve Eriksson
Rabah Soliymani
Johanna Mäkelä
Céline Bruelle
Dan Duc Pham
P2860cites workPeroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulatorQ24294798
Fibroblast growth factor-21 (FGF21) regulates low-density lipoprotein receptor (LDLR) levels in cells via the E3-ubiquitin ligase Mylip/Idol and the Canopy2 (Cnpy2)/Mylip-interacting saposin-like protein (Msap)Q24306597
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Endoplasmic reticulum stress inhibition protects against excitotoxic neuronal injury in the rat brainQ28572076
Connexin-30 mRNA is up-regulated in astrocytes and expressed in apoptotic neuronal cells of rat brain following kainate-induced seizuresQ28578467
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetesQ29547229
Mitochondria: in sickness and in healthQ29614825
Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivatorsQ29617353
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Neuronal expression and regulation of rat inhibitor of apoptosis protein-2 by kainic acid in the rat brainQ31039569
Regulation of X-chromosome-linked inhibitor of apoptosis protein in kainic acid-induced neuronal death in the rat hippocampusQ31937639
Increase in Bcl-2 phosphorylation and reduced levels of BH3-only Bcl-2 family proteins in kainic acid-mediated neuronal death in the rat brainQ33188401
Low abundance of the matrix arm of complex I in mitochondria predicts longevity in miceQ33626717
Destabilization of the outer and inner mitochondrial membranes by core and linker histonesQ34241828
A greatly extended PPARGC1A genomic locus encodes several new brain-specific isoforms and influences Huntington disease age of onsetQ34275231
Fluoro-Jade: a novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degenerationQ34421291
Pgc-1α overexpression downregulates Pitx3 and increases susceptibility to MPTP toxicity associated with decreased BdnfQ34473733
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Transient receptor potential channels and their role in modulating radial glial-neuronal interaction: a signaling pathway involving mGluR5.Q35167135
Fibroblast growth factor-21 enhances mitochondrial functions and increases the activity of PGC-1α in human dopaminergic neurons via Sirtuin-1.Q35537540
Sustained expression of PGC-1α in the rat nigrostriatal system selectively impairs dopaminergic function.Q35856269
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Cell differentiation: reciprocal regulation of Apaf-1 and the inhibitor of apoptosis proteins.Q35927679
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Downregulation of NF-kappaB signaling by mutant huntingtin proteins induces oxidative stress and cell deathQ38345681
NF-kappaB-dependent regulation of brain-derived neurotrophic factor in hippocampal neurons by X-linked inhibitor of apoptosis proteinQ38350697
Proteomic analysis of the palmitoyl protein thioesterase 1 interactome in SH-SY5Y human neuroblastoma cells.Q38888358
Sigma-1 receptor agonist PRE084 is protective against mutant huntingtin-induced cell degeneration: involvement of calpastatin and the NF-κB pathway.Q39148056
Transgenic expression and activation of PGC-1α protect dopaminergic neurons in the MPTP mouse model of Parkinson's diseaseQ39460847
Resveratrol reduces oxidative stress and cell death and increases mitochondrial antioxidants and XIAP in PC6.3-cellsQ39629244
Oxidative stress, glutamate, and neurodegenerative disordersQ40618533
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X-linked inhibitor of apoptosis protein increases mitochondrial antioxidants through NF-kappaB activationQ42823604
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Hippocalcin protects against caspase-12-induced and age-dependent neuronal degenerationQ45193524
Ubiquitin-specific protease-14 reduces cellular aggregates and protects against mutant huntingtin-induced cell degeneration: involvement of the proteasome and ER stress-activated kinase IRE1α.Q45299812
Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.Q45302702
Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1alpha in Huntington's disease neurodegenerationQ45302924
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X chromosome-linked inhibitor of apoptosis protein reduces oxidative stress after cerebral irradiation or hypoxia-ischemia through up-regulation of mitochondrial antioxidantsQ46871281
Irradiation-induced progenitor cell death in the developing brain is resistant to erythropoietin treatment and caspase inhibitionQ47223727
X-linked inhibitor of apoptosis (XIAP) protein protects against caspase activation and tissue loss after neonatal hypoxia-ischemiaQ47320308
Transgenic mice overexpressing XIAP in neurons show better outcome after transient cerebral ischemiaQ48278257
Kainic acid: a powerful neurotoxic analogue of glutamateQ48522293
Involvement of cyclin-dependent kinase-5 in the kainic acid-mediated degeneration of glutamatergic synapses in the rat hippocampusQ48858628
XIAP decreases caspase-12 cleavage and calpain activity in spinal cord of ALS transgenic mice.Q53630502
Translational upregulation of X-linked inhibitor of apoptosis (XIAP) increases resistance to radiation induced cell death.Q54039075
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectexcitotoxicityQ901117
P304page(s)626-639
P577publication date2016-02-11
P1433published inEuropean Journal of NeuroscienceQ5412733
P1476titlePeroxisome proliferator-activated receptor-γ coactivator-1α mediates neuroprotection against excitotoxic brain injury in transgenic mice: role of mitochondria and X-linked inhibitor of apoptosis protein
P478volume43

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