The protective role of peroxisome proliferator-activated receptor γ coactivator-1α in hyperthyroid cardiac hypertrophy

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The protective role of peroxisome proliferator-activated receptor γ coactivator-1α in hyperthyroid cardiac hypertrophy is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/JCP.24015
P698PubMed publication ID22105890

P2093author name stringBo Yu
Wei Xu
Ting Guo
Xiangrui Jiang
Yuan Liu
Chen-Yu Zhang
Ke Zen
Zhiyuan Lu
Dongxia Hou
Dongjin Wang
P2860cites workBioenergetic remodeling of heart mitochondria by thyroid hormoneQ45150714
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Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolismQ28266830
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Incidence, clinical characteristics and outcome of congestive heart failure as the initial presentation in patients with primary hyperthyroidismQ35773368
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Thyroid hormone action at the cellular, genomic and target gene levels.Q36380047
The transcriptional coactivator PGC-1alpha is essential for maximal and efficient cardiac mitochondrial fatty acid oxidation and lipid homeostasisQ36807931
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PGC-1alpha and ERRalpha target gene downregulation is a signature of the failing human heartQ37189947
Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesisQ37526796
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Two thyroid hormone-mediated gene expression patterns in vivo identified by cDNA expression arrays in rat.Q38292596
Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activationQ38302923
Thyroid hormone interacts with PPARalpha and PGC-1 during mitochondrial maturation in sheep heartQ38323548
TNF-alpha reduces PGC-1alpha expression through NF-kappaB and p38 MAPK leading to increased glucose oxidation in a human cardiac cell modelQ39911368
Activation of cardiac Cdk9 represses PGC-1 and confers a predisposition to heart failureQ39996386
PPARγ coactivator-1α expression during thyroid hormone- and contractile activity-induced mitochondrial adaptationsQ40649637
Cytokine stimulation of energy expenditure through p38 MAP kinase activation of PPARgamma coactivator-1.Q40763964
Various hypertrophic stimuli induce distinct phenotypes in cardiomyocytesQ41681244
Thyroid hormone induces cardiac myocyte hypertrophy in a thyroid hormone receptor alpha1-specific manner that requires TAK1 and p38 mitogen-activated protein kinase.Q42139398
PGC-1 alpha regulates expression of myocardial mitochondrial antioxidants and myocardial oxidative stress after chronic systolic overloadQ42406946
Thyroxine-induced cardiac hypertrophy: time course of development and inhibition by propranololQ43554611
Peroxisome proliferator-activated receptor gamma plays a critical role in inhibition of cardiac hypertrophy in vitro and in vivoQ43913705
Hypoxia induces PGC-1α expression and mitochondrial biogenesis in the myocardium of TOF patientsQ44539439
Peroxisome proliferator activated receptor (PPAR)alpha agonists inhibit hypertrophy of neonatal rat cardiac myocytesQ44559335
Cardiac-specific induction of the transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha promotes mitochondrial biogenesis and reversible cardiomyopathy in a developmental stage-dependent mannerQ44730585
Analysis of differentially expressed genes in hyperthyroid-induced hypertrophied heart by cDNA microarrayQ45000071
P433issue9
P304page(s)3243-3253
P577publication date2012-09-01
P1433published inJournal of Cellular PhysiologyQ1524270
P1476titleThe protective role of peroxisome proliferator-activated receptor γ coactivator-1α in hyperthyroid cardiac hypertrophy
P478volume227

Reverse relations

Q90438398Decreased PGC1- α levels and increased apoptotic protein signaling are associated with the maladaptive cardiac hypertrophy in hyperthyroidismcites workP2860

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