| scholarly article | Q13442814 |
| P2093 | author name string | Meng Zhang | |
| Amrita K Cheema | |||
| Yi Chu | |||
| Anelia Horvath | |||
| Nady Golestaneh | |||
| Rency Varghese | |||
| Nisi Jiang | |||
| Olga Postnikova | |||
| P2860 | cites work | Assessment of mitochondrial damage in retinal cells and tissues using quantitative polymerase chain reaction for mitochondrial DNA damage and extracellular flux assay for mitochondrial respiration activity | Q85429402 |
| SIRT1 negatively regulates the mammalian target of rapamycin | Q21142655 | ||
| A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy | Q24316492 | ||
| AMPK phosphorylation of raptor mediates a metabolic checkpoint | Q24329244 | ||
| Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency | Q24541443 | ||
| AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity | Q24595845 | ||
| mTOR is a key modulator of ageing and age-related disease | Q24610741 | ||
| Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks | Q24633890 | ||
| mTOR signaling in growth control and disease | Q24634174 | ||
| Methods for culturing retinal pigment epithelial cells: a review of current protocols and future recommendations | Q26738931 | ||
| PGC-1 proteins and heart failure | Q27008861 | ||
| Regulatory roles for L-arginine in reducing white adipose tissue | Q27021080 | ||
| Ablation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance | Q27335066 | ||
| Guanosine: a Neuromodulator with Therapeutic Potential in Brain Disorders | Q28072158 | ||
| Identification of S6 kinase 1 as a novel mammalian target of rapamycin (mTOR)-phosphorylating kinase | Q28251762 | ||
| Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism | Q28266830 | ||
| Mitochondrial depolarization in glutamate-stimulated neurons: an early signal specific to excitotoxin exposure | Q28289036 | ||
| AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1 | Q28506431 | ||
| PARP-2, A novel mammalian DNA damage-dependent poly(ADP-ribose) polymerase | Q28511873 | ||
| Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha | Q28513388 | ||
| Functions of lysosomes | Q29614182 | ||
| Sirtuins in mammals: insights into their biological function | Q29615248 | ||
| AMPK: a nutrient and energy sensor that maintains energy homeostasis | Q29615410 | ||
| mTOR regulation of autophagy | Q29616301 | ||
| Metabolic control through the PGC-1 family of transcription coactivators | Q29616509 | ||
| mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex | Q29617214 | ||
| Mammalian sirtuins--emerging roles in physiology, aging, and calorie restriction | Q29617574 | ||
| Termination of autophagy and reformation of lysosomes regulated by mTOR | Q29619817 | ||
| AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha | Q29620443 | ||
| Epidemiology of age-related macular degeneration (AMD): associations with cardiovascular disease phenotypes and lipid factors | Q30239897 | ||
| Glutathione oxidation as a trigger of mitochondrial depolarization and oscillation in intact hearts | Q30485060 | ||
| Defective TNF-alpha-mediated hepatocellular apoptosis and liver damage in acidic sphingomyelinase knockout mice | Q30881683 | ||
| Age-related macular degeneration (AMD): pathogenesis and therapy | Q33250352 | ||
| Age-related macular degeneration--emerging pathogenetic and therapeutic concepts | Q33263472 | ||
| Forecasting age-related macular degeneration through the year 2050: the potential impact of new treatments | Q33429803 | ||
| Direct control of mitochondrial function by mTOR. | Q33552261 | ||
| AMPK and SIRT1: a long-standing partnership? | Q33783499 | ||
| Altered bioenergetics and enhanced resistance to oxidative stress in human retinal pigment epithelial cells from donors with age-related macular degeneration | Q33784315 | ||
| Identification of novel substrates for the serine protease HTRA1 in the human RPE secretome | Q33994138 | ||
| Glutathione, oxidative stress and neurodegeneration | Q33994473 | ||
| Proteolytic and lipolytic responses to starvation | Q33997322 | ||
| Autophagy in health and disease. 5. Mitophagy as a way of life | Q34085696 | ||
| Regulation of mitochondrial biogenesis | Q34119796 | ||
| PGC-1α determines light damage susceptibility of the murine retina | Q34163451 | ||
| Drusen deposits associated with aging and age-related macular degeneration contain nonfibrillar amyloid oligomers | Q34331346 | ||
| mTOR-mediated dedifferentiation of the retinal pigment epithelium initiates photoreceptor degeneration in mice. | Q34429001 | ||
| Altered mTOR signaling in senescent retinal pigment epithelium | Q34735293 | ||
| Autophagy activation clears ELAVL1/HuR-mediated accumulation of SQSTM1/p62 during proteasomal inhibition in human retinal pigment epithelial cells | Q34903032 | ||
| PARP-2 regulates SIRT1 expression and whole-body energy expenditure | Q35026114 | ||
| Investigating mitochondria as a target for treating age-related macular degeneration | Q35572570 | ||
| Role of PGC-1α during acute exercise-induced autophagy and mitophagy in skeletal muscle | Q35572598 | ||
| Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD | Q35852752 | ||
| Confluent monolayers of cultured human fetal retinal pigment epithelium exhibit morphology and physiology of native tissue. | Q35865480 | ||
| PGC-1α regulates normal and pathological angiogenesis in the retina | Q36511504 | ||
| The multifaceted role of mTORC1 in the control of lipid metabolism | Q36659049 | ||
| PGC-1α Induces Human RPE Oxidative Metabolism and Antioxidant Capacity | Q36676999 | ||
| Tumour cell survival signalling by the ERK1/2 pathway | Q37290943 | ||
| PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure | Q37412140 | ||
| Repressed SIRT1/PGC-1α pathway and mitochondrial disintegration in iPSC-derived RPE disease model of age-related macular degeneration. | Q37523129 | ||
| Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis | Q37526796 | ||
| Deletion of conserved protein phosphatases reverses defects associated with mitochondrial DNA damage in Saccharomyces cerevisiae | Q37543961 | ||
| Downregulation of PGC-1α Prevents the Beneficial Effect of EET-Heme Oxygenase-1 on Mitochondrial Integrity and Associated Metabolic Function in Obese Mice | Q37549613 | ||
| Dysfunctional autophagy in RPE, a contributing factor in age-related macular degeneration | Q37744895 | ||
| The MAPK cascades: signaling components, nuclear roles and mechanisms of nuclear translocation | Q37822076 | ||
| PGC1α and mitochondrial metabolism--emerging concepts and relevance in ageing and neurodegenerative disorders | Q38070667 | ||
| Crosstalk between Oxidative Stress and SIRT1: Impact on the Aging Process | Q38084036 | ||
| Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation | Q38302923 | ||
| Lipid metabolism, apoptosis and cancer therapy | Q38308411 | ||
| PI3K/AKT/mTOR pathway plays a major pathogenetic role in glycogen accumulation and tumor development in renal distal tubules of rats and men | Q38878276 | ||
| Discrepant NOXA (PMAIP1) transcript and NOXA protein levels: a potential Achilles' heel in mantle cell lymphoma | Q39031250 | ||
| Cancer cell metabolism: the essential role of the nonessential amino acid, glutamine. | Q39249420 | ||
| Glutamate-induced mitochondrial depolarisation and perturbation of calcium homeostasis in cultured rat hippocampal neurones | Q39515826 | ||
| Small molecule metabolite extraction strategy for improving LC/MS detection of cancer cell metabolome. | Q39566899 | ||
| A nucleocytoplasmic malate dehydrogenase regulates p53 transcriptional activity in response to metabolic stress | Q39881896 | ||
| Regulation of AMP-activated protein kinase and acetyl-CoA carboxylase phosphorylation by palmitate in skeletal muscle cells | Q40348347 | ||
| Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1alpha and PGC-1beta) in muscle cells | Q40649634 | ||
| Characterization of the Role of the Malate Dehydrogenases to Lung Tumor Cell Survival | Q41439924 | ||
| mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6. | Q41792378 | ||
| Guanosine prevents nitroxidative stress and recovers mitochondrial membrane potential disruption in hippocampal slices subjected to oxygen/glucose deprivation. | Q42363254 | ||
| PGC-1α modulates denervation-induced mitophagy in skeletal muscle | Q42656304 | ||
| mTOR pathway activation in age-related retinal disease | Q42762402 | ||
| Selective PARP-2 inhibitors increase apoptosis in hippocampal slices but protect cortical cells in models of post-ischaemic brain damage | Q42940200 | ||
| Lipids and lipid metabolism in the eye. | Q42959438 | ||
| Developmental regulation and cellular distribution of human cytosolic malate dehydrogenase (MDH1). | Q45163931 | ||
| Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1alpha in Huntington's disease neurodegeneration | Q45302924 | ||
| Guanosine exerts neuroprotective effects by reversing mitochondrial dysfunction in a cellular model of Parkinson's disease | Q46845100 | ||
| Nicotinamide Ameliorates Disease Phenotypes in a Human iPSC Model of Age-Related Macular Degeneration. | Q51164013 | ||
| SIRT1 prevents pulmonary thrombus formation induced by arachidonic acid via downregulation of PAF receptor expression in platelets. | Q51713855 | ||
| mTOR Signaling in Growth, Metabolism, and Disease. | Q54144950 | ||
| mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation. | Q54398394 | ||
| A map of the PGC-1α- and NT-PGC-1α-regulated transcriptional network in brown adipose tissue. | Q55078959 | ||
| MetaboAnalyst 4.0: towards more transparent and integrative metabolomics analysis. | Q55518708 | ||
| PGC-1α as a Pivotal Factor in Lipid and Metabolic Regulation | Q58616511 | ||
| Human retinal pigment epithelium in vitro: influence of low oxygen tension, glucose and insulin | Q72587541 | ||
| The combination of organoselenium compounds and guanosine prevents glutamate-induced oxidative stress in different regions of rat brains | Q82763217 | ||
| Impact of PGC-1α on the topology and rate of superoxide production by the mitochondrial electron transport chain | Q85027375 | ||
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 1 | |
| P921 | main subject | metabolic pathway | Q68685 |
| macular degeneration | Q27429789 | ||
| P304 | page(s) | 2464 | |
| P577 | publication date | 2020-02-12 | |
| P1433 | published in | Scientific Reports | Q2261792 |
| P1476 | title | Dysregulated metabolic pathways in age-related macular degeneration | |
| P478 | volume | 10 |
| Q97644915 | Metformin Protects ARPE-19 Cells from Glyoxal-Induced Oxidative Stress | cites work | P2860 |
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