scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1100996044 |
P356 | DOI | 10.1186/S13195-018-0342-6 |
P932 | PMC publication ID | 5809956 |
P698 | PubMed publication ID | 29433569 |
P50 | author | Manfred Schubert-Zsilavecz | Q1720710 |
P2093 | author name string | Gunter P Eckert | |
Schamim H Eckert | |||
Mario Wurglics | |||
Dirk Berressem | |||
Heike Asseburg | |||
Maximilian Pohland | |||
Stephanie Hagl | |||
Maren Pellowska | |||
Martina Reutzel | |||
Aljoscha Joppe | |||
P2860 | cites work | Alzheimer's Disease | Q22248111 |
PGC-1alpha expression decreases in the Alzheimer disease brain as a function of dementia | Q24604133 | ||
Rosiglitazone Monotherapy in Mild-to-Moderate Alzheimer’s Disease: Results from a Randomized, Double-Blind, Placebo-Controlled Phase III Study | Q24628969 | ||
The association between PGC-1α and Alzheimer's disease | Q26751165 | ||
Drug development in Alzheimer's disease: the path to 2025 | Q27007748 | ||
Mitochondrial dysfunction: different routes to Alzheimer's disease therapy | Q27009475 | ||
Structure of pig heart citrate synthase at 1.78 Å resolution | Q27655338 | ||
Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism | Q28266830 | ||
Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres | Q29555845 | ||
A "mitochondrial cascade hypothesis" for sporadic Alzheimer's disease | Q30433751 | ||
PGC-1α overexpression exacerbates β-amyloid and tau deposition in a transgenic mouse model of Alzheimer's disease | Q30574513 | ||
Efficacy of MitoTracker Green and CMXrosamine to measure changes in mitochondrial membrane potentials in living cells and tissues | Q33207057 | ||
Nonsteroidal anti-inflammatory drugs repress beta-secretase gene promoter activity by the activation of PPARgamma | Q34249625 | ||
Preserved cognition in patients with early Alzheimer disease and amnestic mild cognitive impairment during treatment with rosiglitazone: a preliminary study | Q34467303 | ||
Characterization of ATP alternations in an Alzheimer's disease transgenic mouse model | Q35007956 | ||
Upregulation of PGC-1α expression by Alzheimer's disease-associated pathway: presenilin 1/amyloid precursor protein (APP)/intracellular domain of APP | Q35093148 | ||
Mitochondrial oxygen consumption deficits in skeletal muscle isolated from an Alzheimer's disease-relevant murine model | Q35093852 | ||
Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease | Q35532902 | ||
Recent development of multifunctional agents as potential drug candidates for the treatment of Alzheimer's disease. | Q35617556 | ||
Mitochondrion-derived reactive oxygen species lead to enhanced amyloid beta formation | Q35898639 | ||
Metabolic Characterization of Intact Cells Reveals Intracellular Amyloid Beta but Not Its Precursor Protein to Reduce Mitochondrial Respiration | Q36231595 | ||
Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells | Q36323368 | ||
Dementia in the oldest old: a multi-factorial and growing public health issue | Q36998379 | ||
PPARgamma agonists as therapeutics for the treatment of Alzheimer's disease | Q37215869 | ||
The Alzheimer's disease mitochondrial cascade hypothesis: an update | Q37261159 | ||
PPARγ-coactivator-1α gene transfer reduces neuronal loss and amyloid-β generation by reducing β-secretase in an Alzheimer's disease model | Q37379771 | ||
The Alzheimer's disease mitochondrial cascade hypothesis: progress and perspectives | Q37656554 | ||
Alzheimer's disease: strategies for disease modification | Q37739810 | ||
Mitochondrial dysfunction: common final pathway in brain aging and Alzheimer's disease--therapeutic aspects | Q37749683 | ||
Brain-derived neurotrophic factor and Alzheimer's disease: physiopathology and beyond | Q37928495 | ||
From mitochondrial dysfunction to amyloid beta formation: novel insights into the pathogenesis of Alzheimer's disease. | Q38029575 | ||
PGC1α and mitochondrial metabolism--emerging concepts and relevance in ageing and neurodegenerative disorders | Q38070667 | ||
Potential novel targets for Alzheimer pharmacotherapy: II. Update on secretase inhibitors and related approaches | Q38169212 | ||
Efficacy and safety of donepezil, galantamine, rivastigmine, and memantine for the treatment of Alzheimer's disease: a systematic review and meta-analysis | Q38198838 | ||
Mitochondrial dysfunction: cause and consequence of Alzheimer's disease | Q38242410 | ||
BDNF: A Key Factor with Multipotent Impact on Brain Signaling and Synaptic Plasticity. | Q38670024 | ||
Amyloid precursor protein processing and bioenergetics | Q38933148 | ||
Rice bran extract compensates mitochondrial dysfunction in a cellular model of early Alzheimer's disease | Q38965848 | ||
Therapeutic potential of nuclear receptor agonists in Alzheimer's disease | Q39164346 | ||
PPARgamma rescue of the mitochondrial dysfunction in Huntington's disease. | Q39476389 | ||
PPARγ co-activator-1α (PGC-1α) reduces amyloid-β generation through a PPARγ-dependent mechanism | Q39584769 | ||
Dimebon ameliorates amyloid-β induced impairments of mitochondrial form and function | Q39632686 | ||
MH84: A Novel γ-Secretase Modulator/PPARγ Agonist--Improves Mitochondrial Dysfunction in a Cellular Model of Alzheimer's Disease | Q40154119 | ||
Peroxisome-proliferator-activated receptor gamma induces a clearance mechanism for the amyloid-beta peptide. | Q40485801 | ||
The role of APP processing and trafficking pathways in the formation of amyloid beta-protein | Q40983150 | ||
¹H- and ¹³C-NMR spectroscopy of Thy-1-APPSL mice brain extracts indicates metabolic changes in Alzheimer's disease | Q41288398 | ||
Pioglitazone attenuates mitochondrial dysfunction, cognitive impairment, cortical tissue loss, and inflammation following traumatic brain injury | Q41886732 | ||
Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease | Q41945324 | ||
PGC-1α or FNDC5 Is Involved in Modulating the Effects of Aβ1-42 Oligomers on Suppressing the Expression of BDNF, a Beneficial Factor for Inhibiting Neuronal Apoptosis, Aβ Deposition and Cognitive Decline of APP/PS1 Tg Mice | Q42210014 | ||
SAR studies of acidic dual γ-secretase/PPARγ modulators | Q42727258 | ||
Design, synthesis, and biological evaluation of a novel class of gamma-secretase modulators with PPARgamma activity | Q43053918 | ||
Mitochondrial dysfunction in a transgenic mouse model expressing human amyloid precursor protein (APP) with the Arctic mutation | Q46649144 | ||
Mitochondrial dysfunction: an early event in Alzheimer pathology accumulates with age in AD transgenic mice | Q46737335 | ||
Simultaneous high-resolution measurement of mitochondrial respiration and hydrogen peroxide production. | Q46780753 | ||
Cardiolipin profile changes are associated to the early synaptic mitochondrial dysfunction in Alzheimer's disease | Q46844046 | ||
Selection of reference genes for quantitative real-time RT-PCR studies in mouse brain. | Q46943029 | ||
Increased localization of APP-C99 in mitochondria-associated ER membranes causes mitochondrial dysfunction in Alzheimer disease | Q47149447 | ||
Mitochondria and Mitochondrial Cascades in Alzheimer's Disease | Q47784287 | ||
Rice bran extract improves mitochondrial dysfunction in brains of aged NMRI mice | Q48035006 | ||
SAR-studies of γ-secretase modulators with PPARγ-agonistic and 5-lipoxygenase-inhibitory activity for Alzheimer's disease | Q48381673 | ||
Pharmacokinetic properties of MH84, a γ-secretase modulator with PPARγ agonistic activity | Q48430096 | ||
Early alterations in energy metabolism in the hippocampus of APPswe/PS1dE9 mouse model of Alzheimer's disease. | Q48742553 | ||
Efficacy of PPAR-γ agonist pioglitazone in mild Alzheimer disease. | Q51411852 | ||
A4 protein in Alzheimer's disease: primary and secondary cellular events in extracellular amyloid deposition. | Q53188363 | ||
Biomarkers of mitochondrial content in skeletal muscle of healthy young human subjects | Q58456009 | ||
Time sequence of maturation of dystrophic neurites associated with Abeta deposits in APP/PS1 transgenic mice | Q79322897 | ||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Alzheimer's disease | Q11081 |
P304 | page(s) | 18 | |
P577 | publication date | 2018-02-13 | |
P1433 | published in | Alzheimers Research & Therapy | Q15716761 |
P1476 | title | MH84 improves mitochondrial dysfunction in a mouse model of early Alzheimer's disease | |
P478 | volume | 10 |
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