Antigen-driven effector CD8 T cell function regulated by T-bet

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Antigen-driven effector CD8 T cell function regulated by T-bet is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2003PNAS..10015818S
P356DOI10.1073/PNAS.2636938100
P932PMC publication ID307651
P698PubMed publication ID14673093
P5875ResearchGate publication ID8961761

P50authorLaurie GlimcherQ6501587
Matthias von HerrathQ64532773
P2093author name stringBrandon M Sullivan
Susanne J Szabo
Amy Juedes
P2860cites workT-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cellsQ74082060
Critical role for STAT4 activation by type 1 interferons in the interferon-gamma response to viral infectionQ74813303
c-Rel is crucial for lymphocyte proliferation but dispensable for T cell effector functionQ77378951
Development of spontaneous airway changes consistent with human asthma in mice lacking T-betQ77476285
A novel transcription factor, T-bet, directs Th1 lineage commitmentQ22253874
Interleukin-10 and the interleukin-10 receptorQ24290912
T cell receptor antagonist peptides induce positive selectionQ29618820
Response to influenza infection in mice with a targeted disruption in the interferon gamma geneQ30442876
In vivo cross-presentation of a soluble protein antigen: kinetics, distribution, and generation of effector CTL recognizing dominant and subdominant epitopesQ31583375
Antigen presentation by MHC class I and its regulation by interferon gammaQ33536525
Transcriptional regulation of T lymphocyte development and functionQ33652463
Protective role of gamma interferon during the recall response to influenza virus.Q33783554
T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cellsQ33952975
Mechanisms of interleukin-10-mediated immune suppressionQ34285968
MAP kinases in the immune responseQ34542231
Influence of effector molecules on the CD8(+) T cell response to infectionQ34612543
Biology and pathogenesis of lymphocytic choriomeningitis virus infection.Q34622909
Effector and memory T-cell differentiation: implications for vaccine developmentQ34632071
CD8 T cell responses to infectious pathogens.Q34987912
Autoimmune diabetes can be induced in transgenic major histocompatibility complex class II-deficient miceQ36362059
Lineage-specific requirement for signal transducer and activator of transcription (Stat)4 in interferon gamma production from CD4(+) versus CD8(+) T cellsQ36368055
The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's diseaseQ36370178
Molecularly engineered vaccine which expresses an immunodominant T-cell epitope induces cytotoxic T lymphocytes that confer protection from lethal virus infection.Q36831093
Biology of cloned cytotoxic T lymphocytes specific for lymphocytic choriomeningitis virus: clearance of virus in vivoQ36918873
Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naïve cellsQ37139786
DNA immunization confers protection against lethal lymphocytic choriomeningitis virus infection.Q39869845
Memory CD8(+) T cells undergo peripheral toleranceQ40714192
Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cellsQ40757721
The molecular cell biology of interferon-gamma and its receptorQ40898233
Cytokine-induced differentiation of precursor mouse CD8+ T cells into cytotoxic CD8+ T cells secreting Th1 or Th2 cytokines.Q41365854
Switch of CD8 T cells to noncytolytic CD8-CD4- cells that make TH2 cytokines and help B cells.Q41547198
Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model: role of anti-self (virus) immune responseQ43986613
Lineage-specific differences among CD8+ T cells in their dependence of NF-kappa B/Rel signalingQ44154232
Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic miceQ45854348
Molecular and functional profiling of memory CD8 T cell differentiation.Q52008481
Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development.Q52111650
Differential effects of IL-12 receptor blockade with IL-12 p40 homodimer on the induction of CD4+ and CD8+ IFN-gamma-producing cellsQ71968307
NF-kappa B is required for the positive selection of CD8+ thymocytesQ73112917
Differential requirement of CD28 for IL-12 receptor expression and function in CD4(+) and CD8(+) T cellsQ73443937
Naïve CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiationQ73808233
P433issue26
P407language of work or nameEnglishQ1860
P921main subjectcell functionQ95674809
P1104number of pages6
P304page(s)15818-15823
P577publication date2003-12-12
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleAntigen-driven effector CD8 T cell function regulated by T-bet
P478volume100

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