Beyond pulmonary hypertension: sildenafil for chronic lung disease of prematurity

scientific article

Beyond pulmonary hypertension: sildenafil for chronic lung disease of prematurity is …
instance of (P31):
scholarly articleQ13442814
editorialQ871232

External links are
P356DOI10.1165/RCMB.2012-0441ED
P698PubMed publication ID23378489

P50authorRobin H SteinhornQ38328592
P2093author name stringSteven H Abman
John P Kinsella
P2860cites workA randomized, double-blind, placebo-controlled, dose-ranging study of oral sildenafil citrate in treatment-naive children with pulmonary arterial hypertensionQ38480301
Functional properties of a brain-specific NH2-terminally spliced modulator of Kv4 channelsQ42595294
Population pharmacokinetics of sildenafil in term neonates: evidence of rapid maturation of metabolic clearance in the early postnatal periodQ42597721
Intravenous sildenafil in the treatment of neonates with persistent pulmonary hypertensionQ43260002
Long-term treatment with sildenafil citrate in pulmonary arterial hypertension: the SUPER-2 studyQ46694356
Effect of preterm birth on hypoxia-inducible factors and vascular endothelial growth factor in primate lungs.Q46758249
Increased 36-week survival with high oxygen saturation target in extremely preterm infants.Q51574827
Oxygen-saturation targets and outcomes in extremely preterm infants.Q52100740
Intrauterine hypertension decreases lung VEGF expression and VEGF inhibition causes pulmonary hypertension in the ovine fetus.Q52109383
Hyperoxic injury decreases alveolar epithelial cell expression of vascular endothelial growth factor (VEGF) in neonatal rabbit lung.Q52194865
Disrupted pulmonary vasculature and decreased vascular endothelial growth factor, Flt-1, and TIE-2 in human infants dying with bronchopulmonary dysplasia.Q52544695
Hypoxia-inducible factors HIF-1alpha and HIF-2alpha are decreased in an experimental model of severe respiratory distress syndrome in preterm lambs.Q52577117
Oral Sildenafil in Infants With Persistent Pulmonary Hypertension of the Newborn: A Pilot Randomized Blinded StudyQ56636803
Studies on the activity of the hypoxia-inducible-factor hydroxylases using an oxygen consumption assayQ24671869
Bronchopulmonary dysplasiaQ28201380
Vascular endothelial growth factor gene therapy increases survival, promotes lung angiogenesis, and prevents alveolar damage in hyperoxia-induced lung injury: evidence that angiogenesis participates in alveolarizationQ28571824
Glu496Ala polymorphism of human P2X7 receptor does not affect its electrophysiological phenotypeQ30320749
Microtubule-dependent PKC-alpha localization in A7r5 smooth muscle cellsQ30897895
Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory diseaseQ33402434
Sildenafil alleviates bronchopulmonary dysplasia in neonatal rats by activating the hypoxia-inducible factor signaling pathwayQ33756664
SOD and inhaled nitric oxide normalize phosphodiesterase 5 expression and activity in neonatal lambs with persistent pulmonary hypertensionQ33994653
Inhaled nitric oxide in preterm infants: an individual-patient data meta-analysis of randomized trialsQ34022590
Mitochondrial oxidant stress increases PDE5 activity in persistent pulmonary hypertension of the newborn.Q34348585
Moderate postnatal hyperoxia accelerates lung growth and attenuates pulmonary hypertension in infant rats after exposure to intra-amniotic endotoxinQ34426107
Sildenafil improves alveolar growth and pulmonary hypertension in hyperoxia-induced lung injuryQ34558395
Nonventilatory strategies for prevention and treatment of bronchopulmonary dysplasia--what is the evidence?Q34804138
Bronchopulmonary dysplasia: where have all the vessels gone? Roles of angiogenic growth factors in chronic lung diseaseQ36330521
Intrauterine pulmonary hypertension impairs angiogenesis in vitro: role of vascular endothelial growth factor nitric oxide signalingQ36330558
Hyperoxia increases phosphodiesterase 5 expression and activity in ovine fetal pulmonary artery smooth muscle cellsQ36498599
Sildenafil attenuates pulmonary inflammation and fibrin deposition, mortality and right ventricular hypertrophy in neonatal hyperoxic lung injury.Q37190561
Oxygen in health and disease: regulation of oxygen homeostasis--clinical implicationsQ37293099
Effects of long-term sildenafil treatment for pulmonary hypertension in infants with chronic lung diseaseQ37308066
Impaired vascular endothelial growth factor signaling in the pathogenesis of neonatal pulmonary vascular diseaseQ37702971
Inhaled nitric oxide in preterm infants: a systematic reviewQ37827270
P433issue2
P921main subjectlung diseaseQ3392853
P304page(s)iii-v
P577publication date2013-02-01
P1433published inAmerican Journal of Respiratory Cell and Molecular BiologyQ4744268
P1476titleBeyond pulmonary hypertension: sildenafil for chronic lung disease of prematurity
P478volume48

Reverse relations

cites work (P2860)
Q37596144Disrupted pulmonary artery cyclic guanosine monophosphate signaling in mice with hyperoxia-induced pulmonary hypertension.
Q35628109Outcomes for extremely premature infants
Q28390572Oxidative Stress and Therapeutic Development in Lung Diseases

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