| scholarly article | Q13442814 |
| P2093 | author name string | A. H. Schinkel | |
| A. K. Groen | |||
| J. J. Smit | |||
| M. van Wijland | |||
| R. Ottenhoff | |||
| R. P. Oude Elferink | |||
| P2860 | cites work | Phosphatidylcholine translocase: a physiological role for the mdr2 gene | Q24319732 |
| Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease | Q24322810 | ||
| Phospholipid transfer proteins | Q28295855 | ||
| Biochemistry of multidrug resistance mediated by the multidrug transporter | Q29616476 | ||
| Lipid sorting in epithelial cells | Q34048821 | ||
| Biliary excretion of lecithin and cholesterol in the dog | Q34070199 | ||
| Is the multidrug transporter a flippase? | Q35317932 | ||
| Immunoperoxidase localization of bile salts in rat liver cells. Evidence for a role of the Golgi apparatus in bile salt transport | Q35590999 | ||
| Biliary physiology in rats with bile ductular cell hyperplasia. Evidence for a secretory function of proliferated bile ductules | Q35810064 | ||
| Lipid flow in bile formation | Q36043160 | ||
| Tubulovesicular transcytotic pathway in isolated rat hepatocyte couplets in culture. Effect of colchicine and taurocholate | Q36453990 | ||
| Mathematical model of biliary lipid secretion: a quantitative analysis of physiological and biochemical data from man and other species | Q36608506 | ||
| The physical chemistry of cholesterol solubility in bile. Relationship to gallstone formation and dissolution in man | Q37052975 | ||
| Secretion of biliary lipids from the hepatocyte. | Q37959450 | ||
| Organization of glycosphingolipids in bilayers and plasma membranes of mammalian cells | Q39494707 | ||
| Biochemistry of bile secretion | Q39672663 | ||
| Mechanism of secretion of biliary lipids: Role of a microtubular system in hepatocellular transport of biliary lipids in the rat | Q40111944 | ||
| Glutathione as a primary osmotic driving force in hepatic bile formation | Q41101555 | ||
| Relation between biliary glutathione excretion and bile acid-independent bile flow | Q41348992 | ||
| Biliary lipid secretion in the rat during infusion of increasing doses of unconjugated bile acids | Q41465445 | ||
| Assembly of the endoplasmic reticulum phospholipid bilayer: the phosphatidylcholine transporter | Q41486427 | ||
| Fluorescent cellular indicators are extruded by the multidrug resistance protein. | Q41520976 | ||
| Membranes and bile formation. Composition of several mammalian biles and their membrane-damaging properties | Q41543325 | ||
| The effects of colchicine on secretion into bile of bile salts, phospholipids, cholesterol and plasma membrane enzymes: bile salts are secreted unaccompanied by phospholipids and cholesterol | Q41884079 | ||
| Rapid kinetic analysis of the bile-salt-dependent secretion of phospholipid, cholesterol and a plasma-membrane enzyme into bile. | Q42012019 | ||
| Retrograde intrabiliary injection of amphipathic materials causes phospholipid secretion into bile. Taurocholate causes phosphatidylcholine secretion, 3-[(3-cholamidopropyl)dimethylammonio]-propane-1-sulphonate (CHAPS) causes mixed phospholipid secr | Q42127655 | ||
| Role of the hepatocyte microtubular system in the excretion of bile salts and biliary lipid: implications for intracellular vesicular transport | Q42518588 | ||
| Liver cell membrane solubilization may control maximum secretory rate of cholic acid in the rat. | Q43416242 | ||
| Critical tables for calculating the cholesterol saturation of native bile | Q52784770 | ||
| Protection against hydrophobic bile salt-induced cell membrane damage by liposomes and hydrophilic bile salts. | Q54685947 | ||
| C27 Bile Acids in Infants with Coprostanic Acidemia and Occurrence of a 3alpha,7alpha,12alpha-Trihydroxy-5beta-C29 Dicarboxylic Bile Acid as a Major Component in Their Serum | Q66980173 | ||
| mdr2 encodes P-glycoprotein expressed in the bile canalicular membrane as determined by isoform-specific antibodies | Q67899133 | ||
| Differential effects of ursodeoxycholic acid and ursocholic acid on the formation of biliary cholesterol crystals in mice | Q68047477 | ||
| Effect of complete sulfation of bile acids on bile formation: role of conjugation and number of sulfate groups | Q68070324 | ||
| Taurocholate stimulates transcytotic vesicular pathways labeled by horseradish peroxidase in the isolated perfused rat liver | Q68796768 | ||
| Choleresis Induced by Secretin: Distinctly Increased Response in Cirrhotics | Q69392212 | ||
| Enzymatic determination of total serum cholesterol | Q69744405 | ||
| beta-Muricholic acid; potentiometric and cholesterol-dissolving properties | Q69780551 | ||
| Enzymatic measurement of choline-containing phospholipids in bile | Q70154249 | ||
| Cell type-dependent effect of phospholipid and cholesterol on bile salt cytotoxicity | Q70221564 | ||
| Transcellular transport of organic anions in hepatocytes: still a long way to go | Q70221849 | ||
| Nature of bile acid maximum secretory rate in the rat | Q71025995 | ||
| The effect of bile salts upon lecithin synthesis | Q71749943 | ||
| Biliary Secretion in a Patient with Cystic Dilation of the Intrahepatic Biliary Tree | Q72059395 | ||
| Bile acids and lipid metabolism. 3. Influence of bile acids on phospholipids in liver and bile of the isolated perfused dog liver | Q72217726 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Heart and neural crest derivatives expressed 1 | Q21494520 |
| P304 | page(s) | 31–38 | |
| P577 | publication date | 1995-01-01 | |
| P1433 | published in | Journal of Clinical Investigation | Q3186904 |
| P1476 | title | Regulation of biliary lipid secretion by mdr2 P-glycoprotein in the mouse | |
| P478 | volume | 95 |
| Q46131227 | ABC-transporters are localized in caveolin-1-positive and reggie-1-negative and reggie-2-negative microdomains of the canalicular membrane in rat hepatocytes |
| Q34116405 | ABCB4 mediates diet-induced hypercholesterolemia in laboratory opossums |
| Q33626857 | ABCB4 mutations underlie hormonal cholestasis but not pediatric idiopathic gallstones. |
| Q28254190 | ABCG5 and ABCG8 require MDR2 for secretion of cholesterol into bile |
| Q33994721 | ABCG5/ABCG8-independent biliary cholesterol excretion in lactating rats |
| Q45108836 | ACAT2 deficiency limits cholesterol absorption in the cholesterol-fed mouse: impact on hepatic cholesterol homeostasis |
| Q71605598 | Adenosine triphosphate-dependent copper transport in human liver |
| Q40017939 | Alteration of viral lipid composition by expression of the phospholipid floppase ABCB4 reduces HIV vector infectivity |
| Q38798757 | Altered expression and function of canalicular transporters during early development of cholestatic liver injury in Abcb4-deficient mice |
| Q41499011 | An integrated analysis of differential miRNA and mRNA expressions in human gallstones |
| Q39436033 | Animal models of biliary injury and altered bile acid metabolism |
| Q57119190 | Animal models to study bile acid metabolism |
| Q30764627 | Bezafibrate stimulates canalicular localization of NBD-labeled PC in HepG2 cells by PPARalpha-mediated redistribution of ABCB4. |
| Q33881922 | Bile formation and secretion |
| Q24306700 | Bile salt-dependent efflux of cellular phospholipids mediated by ATP binding cassette protein B4 |
| Q36754787 | Bile salt-stimulated phospholipid efflux mediated by ABCB4 localized in nonraft membranes. |
| Q34796390 | Biliary cholesterol secretion by the twinned sterol half-transporters ABCG5 and ABCG8 |
| Q37820950 | Biliary cholesterol secretion: more than a simple ABC. |
| Q28362634 | Biliary lipid composition in cholesterol microlithiasis |
| Q37328736 | Biliary lipids and cholesterol gallstone disease |
| Q71949359 | Biliary secretion of anionic polypeptide fraction is not coupled to that of phospholipids and cholesterol in rats |
| Q36661900 | Candida drug resistance protein 1, a major multidrug ATP binding cassette transporter of Candida albicans, translocates fluorescent phospholipids in a reconstituted system. |
| Q43561658 | Cholesterol and cholestasis: a lesson from the Mdr2 (-/-) mouse |
| Q35596277 | Cholesterol synthesis inhibition distal to squalene upregulates biliary phospholipid secretion and counteracts cholelithiasis in the genetically prone C57L/J mouse |
| Q39813339 | Class III P-glycoproteins mediate the formation of lipoprotein X in the mouse |
| Q40741563 | Comparative cytotoxic and cytoprotective effects of taurohyodeoxycholic acid (THDCA) and tauroursodeoxycholic acid (TUDCA) in HepG2 cell line |
| Q50536506 | Decreased Na+-dependent taurocholate uptake and low expression of the sinusoidal Na+-taurocholate cotransporting protein (Ntcp) in livers of mdr2 P-glycoprotein-deficient mice. |
| Q38302411 | Dietary cholesterol does not normalize low plasma cholesterol levels but induces hyperbilirubinemia and hypercholanemia in Mdr2 P-glycoprotein-deficient mice |
| Q28365519 | Down-regulation of intestinal scavenger receptor class B, type I (SR-BI) expression in rodents under conditions of deficient bile delivery to the intestine |
| Q44297587 | Effects of dietary soybean lecithin on plasma lipid transport and hepatic cholesterol metabolism in rats |
| Q50152578 | Elevated biliary calmodulin during gallstone formation: the role of bile acids |
| Q38748384 | Emerging treatments for primary sclerosing cholangitis |
| Q37337378 | Engineered fibroblast growth factor 19 reduces liver injury and resolves sclerosing cholangitis in Mdr2-deficient mice |
| Q74330975 | Extracellular and intracellular regulation of biliary lecithin hydrophobicity |
| Q35889448 | Fibrates and cholestasis |
| Q28509638 | Fibrates induce mdr2 gene expression and biliary phospholipid secretion in the mouse |
| Q36452680 | Function and pathophysiological importance of ABCB4 (MDR3 P-glycoprotein). |
| Q54567592 | Function of the Escherichia coli msbB gene, a multicopy suppressor of htrB knockouts, in the acylation of lipid A. Acylation by MsbB follows laurate incorporation by HtrB. |
| Q36802840 | Function of the htrB high temperature requirement gene of Escherichia coli in the acylation of lipid A: HtrB catalyzed incorporation of laurate |
| Q42049483 | Functional analysis of candidate ABC transporter proteins for sitosterol transport. |
| Q35801843 | Genetic analysis of cholesterol gallstone formation: searching for Lith (gallstone) genes |
| Q43672317 | Genetic polymorphisms of OCT-1 confer susceptibility to severe progression of primary biliary cirrhosis in Japanese patients |
| Q90296417 | Hepatic Autophagy Deficiency Compromises Farnesoid X Receptor Functionality and Causes Cholestatic Injury |
| Q52652409 | Hepatic cytochrome P450 deficiency in mouse models for intrahepatic cholestasis predispose to bile salt-induced cholestasis. |
| Q34471750 | Hepatic glutathione and glutathione S-conjugate transport mechanisms |
| Q37374954 | Hepatic secretion of phospholipid vesicles in the mouse critically depends on mdr2 or MDR3 P-glycoprotein expression. Visualization by electron microscopy |
| Q40462743 | Hepatobiliary secretion of organic compounds; molecular mechanisms of membrane transport |
| Q47720260 | Hepatocyte-specific expression of the human MDR3 P-glycoprotein gene restores the biliary phosphatidylcholine excretion absent in Mdr2 (-/-) mice |
| Q36311265 | Impaired uptake of conjugated bile acids and hepatitis b virus pres1-binding in na(+) -taurocholate cotransporting polypeptide knockout mice. |
| Q46897446 | Increased expression of LXR alpha, ABCG5, ABCG8, and SR-BI in the liver from normolipidemic, nonobese Chinese gallstone patients |
| Q42760437 | Interactions between organic anions, micelles and vesicles in model bile systems |
| Q33591454 | Mechanism of hepatoprotective action of bile salts in liver disease |
| Q42049835 | Mechanisms and functional features of polarized membrane traffic in epithelial and hepatic cells |
| Q34302013 | Microvillar cell surface as a natural defense system against xenobiotics: a new interpretation of multidrug resistance |
| Q43645952 | Modifying hepatic phospholipid synthesis associates with biliary phospholipid secretion rate in a transporter-independent manner in rats: relation to canalicular membrane fluidity |
| Q71732671 | Modulation of hepatic content and biliary excretion of P-glycoproteins in hepatocellular and obstructive cholestasis in the rat |
| Q42160068 | Modulation of intrahepatic cholesterol trafficking: evidence by in vivo antisense treatment for the involvement of sterol carrier protein-2 in newly synthesized cholesterol transport into rat bile |
| Q41563881 | Molecular alterations of canalicular transport systems in experimental models of cholestasis: possible functional correlations |
| Q38240898 | Molecular mechanisms for biliary phospholipid and drug efflux mediated by ABCB4 and bile salts |
| Q33698287 | Molecular regulation of hepatocellular transport systems in cholestasis |
| Q38337911 | MsbA-dependent translocation of lipids across the inner membrane of Escherichia coli |
| Q71554119 | Peripheral neuropathy in mice transgenic for a human MDR3 P-glycoprotein mini-gene |
| Q33725965 | Peroxisome proliferator-activated receptor α activates human multidrug resistance transporter 3/ATP-binding cassette protein subfamily B4 transcription and increases rat biliary phosphatidylcholine secretion |
| Q54067684 | Phospholipid flippase, low HDL levels, and intestinal fat absorption: a new look at the ABCs of enterohepatic lipid flux. |
| Q28141255 | Physical and metabolic factors in gallstone pathogenesis |
| Q52537428 | Postprandial chylomicron formation and fat absorption in multidrug resistance gene 2 P-glycoprotein-deficient mice. |
| Q91826723 | Primary biliary cholangitis: pathogenesis and therapeutic opportunities |
| Q38299627 | Progressive familial intrahepatic cholestasis with high gamma-glutamyltranspeptidase levels in Taiwanese infants: role of MDR3 gene defect? |
| Q40738996 | Prospective study of bezafibrate for the treatment of primary sclerosing cholangitis |
| Q39906684 | Reduction of glycosphingolipid biosynthesis stimulates biliary lipid secretion in mice |
| Q42037788 | Regulation of mdr2 P-glycoprotein expression by bile salts |
| Q44451361 | Relation between hepatic expression of ATP-binding cassette transporters G5 and G8 and biliary cholesterol secretion in mice |
| Q42554469 | Relationship between biliary lipid and protoporphyrin secretion; potential role of mdr2 P-glycoprotein in hepatobiliary organic anion transport |
| Q34466040 | Role of ABC transporters in secretion of cholesterol from liver into bile |
| Q45308433 | Scavenger receptor BI and ABCG5/G8 differentially impact biliary sterol secretion and reverse cholesterol transport in mice |
| Q45917915 | Scavenger receptor class B type I mediates biliary cholesterol secretion independent of ATP-binding cassette transporter g5/g8 in mice. |
| Q54522041 | Single-nucleotide polymorphism analysis of the multidrug resistance protein 3 gene for the detection of clinical progression in Japanese patients with primary biliary cirrhosis. |
| Q44749286 | Spontaneous cholecysto- and hepatolithiasis in Mdr2-/- mice: a model for low phospholipid-associated cholelithiasis. |
| Q37908143 | Targeting the ABCB4 gene to control cholesterol homeostasis |
| Q37464242 | The Multiple Facets of ABCB4 (MDR3) Deficiency |
| Q50115591 | The importance of membrane microdomains for bile salt-dependent biliary lipid secretion |
| Q35761322 | The ins and outs of reverse cholesterol transport |
| Q33591423 | The mechanism of biliary lipid secretion and its defects |
| Q38070531 | The molecular pathogenesis of cholestasis in sepsis |
| Q77182829 | The role of P-glycoprotein and canalicular multispecific organic anion transporter in the hepatobiliary excretion of drugs |
| Q50956249 | The role of bile salt composition in liver pathology of mdr2 (-/-) mice: differences between males and females. |
| Q34089798 | Transgenic overexpression of Abcb11 enhances biliary bile salt outputs, but does not affect cholesterol cholelithogenesis in mice |
| Q41780489 | Transient receptor potential canonical 5 channels plays an essential role in hepatic dyslipidemia associated with cholestasis. |
| Q33714593 | Xenobiotic, bile acid, and cholesterol transporters: function and regulation. |
| Q38357754 | cDNA cloning and tissue-specific expression of the phosphatidylcholine transfer protein gene |
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