| scholarly article | Q13442814 |
| P2093 | author name string | Hiroshi Tanaka | |
| Kiyoshi Takeda | |||
| Shizuo Akira | |||
| Tadatsugu Taniguchi | |||
| Akinori Takaoka | |||
| Yasuyuki Morishita | |||
| Nobuyuki Tanaka | |||
| Tsukasa Shibue | |||
| Eri Oda | |||
| Hideki Murasawa | |||
| P2860 | cites work | PUMA induces the rapid apoptosis of colorectal cancer cells | Q24291462 |
| PUMA, a novel proapoptotic gene, is induced by p53 | Q24291463 | ||
| The DNA damage response: putting checkpoints in perspective | Q28131713 | ||
| Genetic instabilities in human cancers | Q28131826 | ||
| Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis | Q28144256 | ||
| Essential role of Stat6 in IL-4 signalling | Q28276199 | ||
| Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death | Q28363890 | ||
| Bax-deficient mice with lymphoid hyperplasia and male germ cell death | Q28589360 | ||
| Live or let die: the cell's response to p53 | Q29547663 | ||
| p53-dependent apoptosis modulates the cytotoxicity of anticancer agents | Q29615031 | ||
| p53: puzzle and paradigm | Q29618407 | ||
| p53 is required for radiation-induced apoptosis in mouse thymocytes | Q29620281 | ||
| Defying death after DNA damage. | Q34068957 | ||
| Dissecting p53 tumor suppressor functions in vivo | Q34135695 | ||
| The role of the cyclin-dependent kinase inhibitor p21 in apoptosis. | Q34164259 | ||
| The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice | Q34349446 | ||
| BH3-only proteins - evolutionarily conserved proapoptotic Bcl-2 family members essential for initiating programmed cell death. | Q34598392 | ||
| Abrogation of oncogene-associated apoptosis allows transformation of p53-deficient cells | Q35088549 | ||
| bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis | Q36040551 | ||
| Regulated targeting of BAX to mitochondria. | Q36255507 | ||
| Apoptosis. Biochemical events and relevance to cancer chemotherapy | Q36360000 | ||
| Inactivation of p53 enhances sensitivity to multiple chemotherapeutic agents | Q41228017 | ||
| Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells | Q43514949 | ||
| Bcl-xL deamidation is a critical switch in the regulation of the response to DNA damage | Q44173674 | ||
| Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice. | Q49165929 | ||
| Thymocyte apoptosis induced by p53-dependent and independent pathways. | Q54242475 | ||
| P433 | issue | 18 | |
| P921 | main subject | apoptotic process | Q14599311 |
| Transformation related protein 53 | Q14818136 | ||
| Cyclin-dependent kinase inhibitor 1A (P21) | Q14902457 | ||
| protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | Q14905369 | ||
| BCL2-associated X protein | Q14905404 | ||
| Phorbol-12-myristate-13-acetate-induced protein 1 | Q21428178 | ||
| P304 | page(s) | 2233–2238 | |
| P577 | publication date | 2003-09-15 | |
| P1433 | published in | Genes & Development | Q1524533 |
| P1476 | title | Integral role of Noxa in p53-mediated apoptotic response | |
| P478 | volume | 17 |
| Q53467671 | 5-Aza-2'-deoxycytidine restores proapoptotic function of p53 in cancer cells resistant to p53-induced apoptosis. |
| Q38810868 | A NOXA/MCL-1 Imbalance Underlies Chemoresistance of Malignant Rhabdoid Tumor Cells |
| Q33436060 | Activation of p53-regulated pro-apoptotic signaling pathways in PrP-mediated myopathy |
| Q37365385 | Activation of tumor suppressor protein p53 is required for Theiler's murine encephalomyelitis virus-induced apoptosis in M1-D macrophages |
| Q37098812 | Aiolos collaborates with Blimp-1 to regulate the survival of multiple myeloma cells |
| Q42922881 | An ERK-dependent pathway to Noxa expression regulates apoptosis by platinum-based chemotherapeutic drugs. |
| Q36109186 | An interconnected hierarchical model of cell death regulation by the BCL-2 family |
| Q89621832 | Analysis of Gene Expression in 4,4'-Methylenedianiline-induced Acute Hepatotoxicity |
| Q81399005 | Anoikis |
| Q39028687 | Anoikis and EMT: Lethal "Liaisons" during Cancer Progression |
| Q26852158 | Anoikis molecular pathways and its role in cancer progression |
| Q37028788 | Apoptosis commitment--translating survival signals into decisions on mitochondria |
| Q39441853 | Apoptosis induced by mammalian reovirus is beta interferon (IFN) independent and enhanced by IFN regulatory factor 3- and NF-κB-dependent expression of Noxa |
| Q35854115 | Apoptosis regulation in the mammary gland |
| Q36226739 | Apoptotic pathways and therapy resistance in human malignancies |
| Q41876950 | Autophagy and cell death |
| Q36935301 | BCL-2 family regulation by the 20S proteasome inhibitor bortezomib |
| Q36501194 | BCL2 family in DNA damage and cell cycle control |
| Q95840394 | BH3 mimetics selectively eliminate chemotherapy-induced senescent cells and improve response in TP53 wild-type breast cancer |
| Q48478195 | BH3-only proapoptotic Bcl-2 family members Noxa and Puma mediate neural precursor cell death. |
| Q41837676 | BH3-only proteins Puma and Bim are rate-limiting for gamma-radiation- and glucocorticoid-induced apoptosis of lymphoid cells in vivo. |
| Q34085370 | BH3-only proteins in apoptosis and beyond: an overview |
| Q35883875 | BH3-only proteins in apoptosis at a glance |
| Q36463059 | BH3-only proteins in cell death initiation, malignant disease and anticancer therapy. |
| Q36435312 | BH3-only proteins: integrated control point of apoptosis |
| Q37373448 | Bcl2 family proteins in carcinogenesis and the treatment of cancer. |
| Q38849807 | Brazilian green propolis induced apoptosis in human lung cancer A549 cells through mitochondrial-mediated pathway |
| Q28298792 | C. elegans ced-13 can promote apoptosis and is induced in response to DNA damage |
| Q99350036 | CHIP ubiquitylates NOXA and induces its lysosomal degradation in response to DNA damage |
| Q35138662 | Cell cycle-dependent expression of Dub3, Nanog and the p160 family of nuclear receptor coactivators (NCoAs) in mouse embryonic stem cells |
| Q45240553 | Chronic lymphocytic leukemia cells display p53-dependent drug-induced Puma upregulation |
| Q36728827 | Clinical significance of the p53 pathway and associated gene therapy in non-small cell lung cancers |
| Q36423938 | Clues from worms: a Slug at Puma promotes the survival of blood progenitors |
| Q28587336 | Combined loss of proapoptotic genes Bak or Bax with Bim synergizes to cause defects in hematopoiesis and in thymocyte apoptosis |
| Q36174216 | Comparative Assessment of Vitamin-B12, Folic Acid and Homocysteine Levels in Relation to p53 Expression in Megaloblastic Anemia |
| Q28511476 | Concomitant loss of proapoptotic BH3-only Bcl-2 antagonists Bik and Bim arrests spermatogenesis |
| Q38172752 | Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy. |
| Q39563936 | Cycloheximide suppresses radiation-induced apoptosis in MOLT-4 cells with Arg72 variant of p53 through translational inhibition of p53 accumulation |
| Q48297523 | DNA damage responses and p53 in the aging process. |
| Q36392786 | DNA damage-induced primordial follicle oocyte apoptosis and loss of fertility require TAp63-mediated induction of Puma and Noxa |
| Q35815150 | DNA-damage response network at the crossroads of cell-cycle checkpoints, cellular senescence and apoptosis |
| Q34474734 | DNA-dependent protein kinase catalytic subunit mediates T-cell loss in rheumatoid arthritis |
| Q37921609 | Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases |
| Q37966330 | Deconstructing p53 transcriptional networks in tumor suppression |
| Q39521147 | Developmental arrest of T cells in Rpl22-deficient mice is dependent upon multiple p53 effectors |
| Q24306130 | Differential contribution of Puma and Noxa in dual regulation of p53-mediated apoptotic pathways |
| Q24293924 | Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function |
| Q64956138 | Discussion of some 'knowns' and some 'unknowns' about the tumour suppressor p53. |
| Q36423933 | Dissecting p53-dependent apoptosis. |
| Q41762088 | Distinct cellular and therapeutic effects of obatoclax in rituximab-sensitive and -resistant lymphomas. |
| Q28295846 | E1A activates transcription of p73 and Noxa to induce apoptosis |
| Q35419363 | ELK4 neutralization sensitizes glioblastoma to apoptosis through downregulation of the anti-apoptotic protein Mcl-1 |
| Q37260986 | Effects of the monoamine oxidase inhibitors pargyline and tranylcypromine on cellular proliferation in human prostate cancer cells |
| Q24300781 | Endoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53 |
| Q34104845 | Epithelial ablation of Bcl-XL increases sensitivity to oxygen without disrupting lung development |
| Q28740916 | Estrogen-mediated upregulation of Noxa is associated with cell cycle progression in estrogen receptor-positive breast cancer cells |
| Q38844846 | Etoposide Induces Necrosis Through p53-Mediated Antiapoptosis in Human Kidney Proximal Tubule Cells |
| Q35657414 | Fas death receptor signalling: roles of Bid and XIAP. |
| Q36696093 | Fhit-deficient normal and cancer cells are mitomycin C and UVC resistant |
| Q40025069 | Functional epigenomics approach to identify methylated candidate tumour suppressor genes in renal cell carcinoma |
| Q38671984 | Gene Expression Profiling Identifies Important Genes Affected by R2 Compound Disrupting FAK and P53 Complex |
| Q37169475 | Genomic analyses of musashi1 downstream targets show a strong association with cancer-related processes |
| Q79370601 | Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies |
| Q49922823 | How does p53 induce apoptosis and how does this relate to p53-mediated tumour suppression? |
| Q36879036 | How important are post-translational modifications in p53 for selectivity in target-gene transcription and tumour suppression? |
| Q36394994 | How the Bcl-2 family of proteins interact to regulate apoptosis. |
| Q39577806 | Hypoxic human cancer cells are sensitized to BH-3 mimetic–induced apoptosis via downregulation of the Bcl-2 protein Mcl-1. |
| Q88221537 | Identification of genomic locus responsible for experimentally induced testicular teratoma 1 (ett1) on mouse Chr 18 |
| Q34280884 | In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute |
| Q35664020 | In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation |
| Q34973849 | Inactivation of PNKP by mutant ATXN3 triggers apoptosis by activating the DNA damage-response pathway in SCA3 |
| Q40499172 | Inhibition of glucocorticoid-induced apoptosis by targeting the major splice variants of BIM mRNA with small interfering RNA and short hairpin RNA. |
| Q34685759 | Inhibition of p53 deSUMOylation exacerbates puromycin aminonucleoside-induced apoptosis in podocytes |
| Q28247124 | Inhibitory effect of c-Myc on p53-induced apoptosis in leukemia cells. Microarray analysis reveals defective induction of p53 target genes and upregulation of chaperone genes |
| Q37383229 | Interrogating the relevance of mitochondrial apoptosis for vertebrate development and postnatal tissue homeostasis |
| Q36384554 | Intestinal mucositis: the role of the Bcl-2 family, p53 and caspases in chemotherapy-induced damage. |
| Q38200606 | Intestinal stem cell injury and protection during cancer therapy |
| Q24294698 | Involvement of Noxa in cellular apoptotic responses to interferon, double-stranded RNA, and virus infection |
| Q38271048 | Involvement of Noxa in mediating cellular ER stress responses to lytic virus infection |
| Q37615064 | Is p53 Involved in Tissue-Specific Insulin Resistance Formation? |
| Q36319385 | Kaiso depletion attenuates the growth and survival of triple negative breast cancer cells |
| Q93016524 | Korean Red Ginseng Extract Increases Apoptosis by Activation of the Noxa Pathway in Colorectal Cancer |
| Q36294226 | Life in the balance: how BH3-only proteins induce apoptosis. |
| Q36509870 | Loss of the BH3-only protein Bmf impairs B cell homeostasis and accelerates gamma irradiation-induced thymic lymphoma development |
| Q58553823 | Mcl-1 and Bcl-xL are essential for survival of the developing nervous system |
| Q33926796 | Mechanisms of apoptosis on human lens epithelium after ultraviolet light exposure |
| Q37566211 | Mimicking the BH3 domain to kill cancer cells |
| Q50221065 | Molecular Cell Biology of Apoptosis and Necroptosis in Cancer |
| Q36835812 | Molecular mechanisms of drug resistance in acute myeloid leukaemia |
| Q40589278 | Molecular pathways executing the "trophic sentinel" response in HPV-16 E7-expressing normal human diploid fibroblasts upon growth factor deprivation |
| Q33997232 | Multiple distinct molecular mechanisms influence sensitivity and resistance to MDM2 inhibitors in adult acute myelogenous leukemia |
| Q35741889 | NBK/BIK antagonizes MCL-1 and BCL-XL and activates BAK-mediated apoptosis in response to protein synthesis inhibition |
| Q38866647 | Noxa and cancer therapy: Tuning up the mitochondrial death machinery in response to chemotherapy |
| Q28509111 | Noxa is a critical mediator of p53-dependent motor neuron death after nerve injury in adult mouse |
| Q36088654 | Noxa/Mcl-1 balance regulates susceptibility of cells to camptothecin-induced apoptosis |
| Q37566236 | Noxa: at the tip of the balance between life and death. |
| Q40066192 | Oncogenic KRAS sensitises colorectal tumour cells to chemotherapy by p53-dependent induction of Noxa |
| Q35040007 | PARP-2 deficiency affects the survival of CD4+CD8+ double-positive thymocytes. |
| Q42937925 | Partners in death: a role for p73 and NF-kB in promoting apoptosis |
| Q47074055 | Perp is required for tissue-specific cell survival during zebrafish development |
| Q33832757 | Perturbation of the Bcl-2 network and an induced Noxa/Bcl-xL interaction trigger mitochondrial dysfunction after DNA damage |
| Q37099682 | Piceatannol enhances cisplatin sensitivity in ovarian cancer via modulation of p53, X-linked inhibitor of apoptosis protein (XIAP), and mitochondrial fission |
| Q92265679 | Polarity signaling ensures epidermal homeostasis by coupling cellular mechanics and genomic integrity |
| Q90698156 | Potential synergistic effects of sorafenib and CP-31398 for treating anaplastic thyroid cancer with p53 mutations |
| Q36727232 | Prima-1 induces apoptosis in bladder cancer cell lines by activating p53. |
| Q36360433 | Proapoptotic BH3-only protein Bim is essential for developmentally programmed death of germinal center-derived memory B cells and antibody-forming cells |
| Q24302494 | Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins |
| Q41860419 | Puma and to a lesser extent Noxa are suppressors of Myc-induced lymphomagenesis |
| Q24677017 | Puma cooperates with Bim, the rate-limiting BH3-only protein in cell death during lymphocyte development, in apoptosis induction |
| Q61443678 | SETD3 is a positive regulator of DNA-damage-induced apoptosis |
| Q36293819 | Sall2 is required for proapoptotic Noxa expression and genotoxic stress-induced apoptosis by doxorubicin |
| Q28594218 | Siva is an apoptosis-selective p53 target gene important for neuronal cell death |
| Q53296362 | Srg3, a mouse homolog of BAF155, is a novel p53 target and acts as a tumor suppressor by modulating p21(WAF1/CIP1) expression. |
| Q34354073 | Stat1 activation attenuates IL-6 induced Stat3 activity but does not alter apoptosis sensitivity in multiple myeloma |
| Q40102569 | Stress via p53 pathway causes apoptosis by mitochondrial Noxa upregulation in doxorubicin-treated neuroblastoma cells |
| Q50930237 | Subversion of the Bcl-2 life/death switch in cancer development and therapy. |
| Q26765447 | Targeting Cell Survival Proteins for Cancer Cell Death |
| Q26866936 | Targeting the Bcl-2 family for cancer therapy |
| Q42064781 | The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized. |
| Q39992436 | The BH3-only member Noxa causes apoptosis in melanoma cells by multiple pathways |
| Q24650702 | The BH3-only protein Puma plays an essential role in cytokine deprivation induced apoptosis of mast cells |
| Q35180339 | The Role of BH3-Only Proteins in Tumor Cell Development, Signaling, and Treatment |
| Q34156107 | The emerging roles of microRNAs in the molecular responses of metabolic rate depression |
| Q35083049 | The essential role of evasion from cell death in cancer |
| Q38034268 | The fourth dimension in immunological space: how the struggle for nutrients selects high-affinity lymphocytes. |
| Q49017323 | The long noncoding RNA-ROR promotes the resistance of radiotherapy for human colorectal cancer cells by targeting the p53/miR-145 pathway |
| Q52760105 | The miR-183/ItgA3 axis is a key regulator of prosensory area during early inner ear development. |
| Q41489275 | The p53-Bcl-2 connection |
| Q46111122 | The p53QS transactivation-deficient mutant shows stress-specific apoptotic activity and induces embryonic lethality |
| Q37349700 | The proapoptotic BH3-only, Bcl-2 family member, Puma is critical for acute ethanol-induced neuronal apoptosis |
| Q24314582 | The proapoptotic function of Noxa in human leukemia cells is regulated by the kinase Cdk5 and by glucose |
| Q47398684 | The resurrection of the PIDDosome - emerging roles in the DNA-damage response and centrosome surveillance |
| Q36047162 | The role of BH3-only proteins in the immune system |
| Q38715430 | Thirty years of BCL-2: translating cell death discoveries into novel cancer therapies |
| Q36288668 | Tumor cell-selective regulation of NOXA by c-MYC in response to proteasome inhibition. |
| Q38824332 | Tumor-Suppressor Functions of the TP53 Pathway |
| Q36117765 | Ultraviolet radiation triggers apoptosis of fibroblasts and skin keratinocytes mainly via the BH3-only protein Noxa. |
| Q34705762 | Uncovering gene regulatory networks during mouse fetal germ cell development |
| Q37636467 | Ursolic Acid-Regulated Energy Metabolism-Reliever or Propeller of Ultraviolet-Induced Oxidative Stress and DNA Damage? |
| Q91745097 | mEAK-7 Forms an Alternative mTOR Complex with DNA-PKcs in Human Cancer |
| Q35225097 | p21 delays tumor onset by preservation of chromosomal stability |
| Q92500329 | p53 as a hub in cellular redox regulation and therapeutic target in cancer |
| Q33972469 | p53 directly suppresses BNIP3 expression to protect against hypoxia-induced cell death. |
| Q61798614 | p53 induces senescence through Lamin A/C stabilization-mediated nuclear deformation |
| Q34163536 | p53-Dependent transcriptional responses to interleukin-3 signaling |
| Q34397020 | p53-mediated apoptosis requires inositol hexakisphosphate kinase-2 |
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