scholarly article | Q13442814 |
P50 | author | Paul N Moynagh | Q37379627 |
John J Callanan | Q45423950 | ||
Bernard P. Mahon | Q45449019 | ||
Bingwei Wang | Q63562507 | ||
Mark Mellett | Q81251511 | ||
Jakub Siednienko | Q103780386 | ||
P2093 | author name string | Shuo Yang | |
Nezira Delagic | |||
Ruaidhri Jackson | |||
Lisa S Tang | |||
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TAK1 is a ubiquitin-dependent kinase of MKK and IKK | Q24291454 | ||
Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3... | Q24297037 | ||
Pellino proteins are more than scaffold proteins in TLR/IL-1R signalling: a role as novel RING E3-ubiquitin-ligases | Q24298607 | ||
Pellino2 activates the mitogen activated protein kinase pathway | Q24305052 | ||
Characterization of Pellino2, a substrate of IRAK1 and IRAK4 | Q24308089 | ||
Toll-like receptor 3-mediated activation of NF-kappaB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-beta | Q24311833 | ||
Direct activation of protein kinases by unanchored polyubiquitin chains | Q24324679 | ||
Pellino 1 is required for interleukin-1 (IL-1)-mediated signaling through its interaction with the IL-1 receptor-associated kinase 4 (IRAK4)-IRAK-tumor necrosis factor receptor-associated factor 6 (TRAF6) complex | Q24337456 | ||
IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase | Q24534145 | ||
Pellino Proteins Contain a Cryptic FHA Domain that Mediates Interaction with Phosphorylated IRAK1 | Q27653149 | ||
Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6 | Q28115232 | ||
IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway | Q28190704 | ||
Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4 | Q28211574 | ||
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TRAF6 is a signal transducer for interleukin-1 | Q28291934 | ||
The ubiquitin ligase Peli1 negatively regulates T cell activation and prevents autoimmunity | Q28505401 | ||
Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production | Q28511245 | ||
Cutting edge: mouse pellino-2 modulates IL-1 and lipopolysaccharide signaling | Q28511311 | ||
Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6 | Q28584723 | ||
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Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus | Q29615029 | ||
Type I interferons in host defense | Q29615912 | ||
MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways | Q29616209 | ||
Ubiquitin signalling in the NF-kappaB pathway | Q29616322 | ||
TRAF6 establishes innate immune responses by activating NF-kappaB and IRF7 upon sensing cytosolic viral RNA and DNA. | Q33455769 | ||
RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation | Q34311133 | ||
Pellino3 is a novel upstream regulator of p38 MAPK and activates CREB in a p38-dependent manner | Q34421538 | ||
Kinase-active interleukin-1 receptor-associated kinases promote polyubiquitination and degradation of the Pellino family: direct evidence for PELLINO proteins being ubiquitin-protein isopeptide ligases | Q34659316 | ||
Interferons in autoimmune and inflammatory diseases: regulation and roles | Q35603598 | ||
Type I interferons (alpha/beta) in immunity and autoimmunity | Q36072422 | ||
Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity. | Q36157993 | ||
TLR signalling and activation of IRFs: revisiting old friends from the NF-kappaB pathway | Q36188288 | ||
The NF-kappaB pathway | Q36284035 | ||
Pellino proteins: novel players in TLR and IL-1R signalling | Q36884257 | ||
Identification of the phosphorylation sites on the E3 ubiquitin ligase Pellino that are critical for activation by IRAK1 and IRAK4. | Q37118880 | ||
The Pellino family: IRAK E3 ligases with emerging roles in innate immune signalling | Q37330930 | ||
Pellino-1, an adaptor protein of interleukin-1 receptor/toll-like receptor signaling, is sumoylated by Ubc9. | Q37532221 | ||
Mal mediates TLR-induced activation of CREB and expression of IL-10. | Q39577038 | ||
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TRAF6 and the three C-terminal lysine sites on IRF7 are required for its ubiquitination-mediated activation by the tumor necrosis factor receptor family member latent membrane protein 1 | Q39949585 | ||
The IRAK-catalysed activation of the E3 ligase function of Pellino isoforms induces the Lys63-linked polyubiquitination of IRAK1. | Q40053108 | ||
The synthetic cannabinoid R(+)WIN 55,212-2 inhibits the interleukin-1 signaling pathway in human astrocytes in a cannabinoid receptor-independent manner | Q40384271 | ||
Pellino3, a novel member of the Pellino protein family, promotes activation of c-Jun and Elk-1 and may act as a scaffolding protein | Q42152339 | ||
Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation | Q45345604 | ||
Toll-like receptor 3 is an essential component of the innate stress response in virus-induced cardiac injury | Q45412912 | ||
The role of TBK1 and IKKε in the expression and activation of Pellino 1. | Q49957175 | ||
Thogoto virus ML protein is a potent inhibitor of the interferon regulatory factor-7 transcription factor | Q57017358 | ||
Identification of the protein kinases that activate the E3 ubiquitin ligase Pellino 1 in the innate immune system | Q62001017 | ||
Peli1 (rel)ieves autoimmunity | Q84968422 | ||
P433 | issue | 11 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | toll-like receptor | Q408004 |
Interferon regulatory factor 7 | Q21496522 | ||
TNF receptor-associated factor 6 | Q21497539 | ||
Pellino 3 | Q21980069 | ||
P304 | page(s) | 1055-1062 | |
P577 | publication date | 2012-10-07 | |
P1433 | published in | Nature Immunology | Q1071725 |
P1476 | title | Pellino3 targets the IRF7 pathway and facilitates autoregulation of TLR3- and viral-induced expression of type I interferons | |
P478 | volume | 13 |
Q37492031 | Autophagy, TGF-β, and SMAD-2/3 Signaling Regulates Interferon-β Response in Respiratory Syncytial Virus Infected Macrophages |
Q38768063 | Cutting Edge: A Cullin-5-TRAF6 Interaction Promotes TRAF6 Polyubiquitination and Lipopolysaccharide Signaling. |
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Q38530624 | Molecular and physiological roles of Pellino E3 ubiquitin ligases in immunity |
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Q33762011 | Pellino 1 inactivates mitotic spindle checkpoint by targeting BubR1 for ubiquitinational degradation |
Q35140039 | Pellino 1 promotes lymphomagenesis by deregulating BCL6 polyubiquitination. |
Q36322355 | Pellino-3 promotes endotoxin tolerance and acts as a negative regulator of TLR2 and TLR4 signaling. |
Q24338172 | Pellino3 targets RIP1 and regulates the pro-apoptotic effects of TNF-α |
Q28513622 | Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis |
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Q40409510 | Protective coding variants in CFH and PELI3 and a variant near CTRB1 are associated with age-related macular degeneration†. |
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Q55134544 | The E3 ubiquitin ligase Pellino2 mediates priming of the NLRP3 inflammasome. |
Q41965110 | The pellino e3 ubiquitin ligases recognize specific phosphothreonine motifs and have distinct substrate specificities |
Q38180347 | The roles of Pellino E3 ubiquitin ligases in immunity |
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Q94521239 | miR-744-5p contributes to ocular inflammation in patients with primary Sjogrens Syndrome |