| scholarly article | Q13442814 |
| P50 | author | Antonio Baldini | Q89356799 |
| Masae Morishima | Q124365218 | ||
| P2093 | author name string | Ilaria Taddei | |
| Francesca Vitelli | |||
| Elizabeth A. Lindsay | |||
| P433 | issue | 8 | |
| P921 | main subject | T-box 1 | Q21980210 |
| circulatory system | Q11068 | ||
| P304 | page(s) | 915–922 | |
| P577 | publication date | 2002-04-15 | |
| P1433 | published in | Human Molecular Genetics | Q2720965 |
| P1476 | title | Tbx1 mutation causes multiple cardiovascular defects and disrupts neural crest and cranial nerve migratory pathways | |
| P478 | volume | 11 |
| Q36477668 | 22q11 Gene dosage establishes an adaptive range for sonic hedgehog and retinoic acid signaling during early development. |
| Q37669766 | 22q11 deletion syndrome: a role for TBX1 in pharyngeal and cardiovascular development |
| Q36988231 | 22q11.2 deletion syndrome |
| Q37685976 | A 3 base pair deletion in TBX1 leads to reduced protein expression and transcriptional activity |
| Q37104145 | A case report of truncus arteriosus communis and genetic counseling |
| Q52087883 | A chicken model for DGCR6 as a modifier gene in the DiGeorge critical region. |
| Q35163449 | A defect in early myogenesis causes Otitis media in two mouse models of 22q11.2 Deletion Syndrome |
| Q80565985 | A fate map of Tbx1 expressing cells reveals heterogeneity in the second cardiac field |
| Q38072446 | A molecular and genetic outline of cardiac morphogenesis. |
| Q92502799 | A single-cell transcriptional roadmap for cardiopharyngeal fate diversification |
| Q28513260 | Absence of the vagus nerve in the stomach of Tbx1−/− mutant mice |
| Q37322518 | Alterations in midline cortical thickness and gyrification patterns mapped in children with 22q11.2 deletions |
| Q50701627 | Altered Tbx1 gene expression is associated with abnormal oesophageal development in the adriamycin mouse model of oesophageal atresia/tracheo-oesophageal fistula. |
| Q49240917 | An FGF-driven feed-forward circuit patterns the cardiopharyngeal mesoderm in space and time. |
| Q28586170 | Ash2l interacts with Tbx1 and is required during early embryogenesis |
| Q59330359 | Asymmetry in Mechanosensitive Gene Expression during Aortic Arch Morphogenesis |
| Q64231249 | Atypical nested 22q11.2 duplications between LCR22B and LCR22D are associated with neurodevelopmental phenotypes including autism spectrum disorder with incomplete penetrance |
| Q33714238 | Beta-catenin deficiency causes DiGeorge syndrome-like phenotypes through regulation of Tbx1. |
| Q37219660 | Candidate genes and the behavioral phenotype in 22q11.2 deletion syndrome. |
| Q38931945 | Cardiac Embryology and Molecular Mechanisms of Congenital Heart Disease: A Primer for Anesthesiologists |
| Q51981254 | Cardiovascular development and the colonizing cardiac neural crest lineage. |
| Q47612304 | Cell-autonomous and nonautonomous actions of endothelin-A receptor signaling in craniofacial and cardiovascular development |
| Q38667783 | Cellular and molecular events on the development of mammalian thyroid C cells |
| Q90480746 | Cellular organization and boundary formation in craniofacial development |
| Q30488004 | Chick Lrrn2, a novel downstream effector of Hoxb1 and Shh, functions in the selective targeting of rhombomere 4 motor neurons |
| Q48318063 | Chromosomal Imbalances in Patients with Congenital Cardiac Defects: A Meta-analysis Reveals Novel Potential Critical Regions Involved in Heart Development |
| Q35048477 | Clinical and molecular cytogenetic studies of an unrecognised 22q11.2 deletion in three families |
| Q48228592 | Cloning and characterization of zebrafish tbx1. |
| Q35843311 | Combinatorial transcriptional interaction within the cardiac neural crest: a pair of HANDs in heart formation. |
| Q31126889 | Conditional and constitutive expression of a Tbx1-GFP fusion protein in mice |
| Q52846705 | Congenital diaphragmatic hernia in 22q11.2 deletion syndrome. |
| Q48812094 | Cortical Development Requires Mesodermal Expression of Tbx1, a Gene Haploinsufficient in 22q11.2 Deletion Syndrome |
| Q35128228 | Cranial skeletal biology. |
| Q92307843 | Craniofacial, orofacial and dental disorders: the role of the RAS/ERK pathway |
| Q78739581 | Cre-constructing the heart |
| Q47194311 | Cre-mediated excision of Fgf8 in the Tbx1 expression domain reveals a critical role for Fgf8 in cardiovascular development in the mouse |
| Q35606917 | Crkl deficiency disrupts Fgf8 signaling in a mouse model of 22q11 deletion syndromes. |
| Q36205433 | Cyp26 Enzymes Facilitate Second Heart Field Progenitor Addition and Maintenance of Ventricular Integrity |
| Q52574335 | Cyp26 genes a1, b1 and c1 are down-regulated in Tbx1 null mice and inhibition of Cyp26 enzyme function produces a phenocopy of DiGeorge Syndrome in the chick. |
| Q30503216 | Decreased embryonic retinoic acid synthesis results in a DiGeorge syndrome phenotype in newborn mice |
| Q33829670 | Decreased levels of embryonic retinoic acid synthesis accelerate recovery from arterial growth delay in a mouse model of DiGeorge syndrome |
| Q57812421 | Defective Vagal Innervation in Murine Tbx1 Mutant Hearts |
| Q36496880 | Definitive endoderm of the mouse embryo: formation, cell fates, and morphogenetic function |
| Q38817031 | Development of the intrinsic and extrinsic innervation of the gut. |
| Q52087506 | Developmental expression of the amphioxus Tbx1/ 10 gene illuminates the evolution of vertebrate branchial arches and sclerotome. |
| Q58193810 | DiGeorge subtypes of nonsyndromic conotruncal defects: evidence against a major role of TBX1 Gene |
| Q42862708 | DiGeorge syndrome, Tbx1, and retinoic acid signaling come full circle |
| Q81887412 | DiGeorge's syndrome presenting as hypocalcemia in an adult |
| Q36618064 | Disruption of Smad4 in neural crest cells leads to mid-gestation death with pharyngeal arch, craniofacial and cardiac defects |
| Q51829029 | Dual role for neural crest cells during outflow tract septation in the neural crest-deficient mutant Splotch(2H). |
| Q37566124 | Dysphagia and disrupted cranial nerve development in a mouse model of DiGeorge (22q11) deletion syndrome |
| Q28507003 | Ece1 and Tbx1 define distinct pathways to aortic arch morphogenesis |
| Q34341624 | Ectopic TBX1 suppresses thymic epithelial cell differentiation and proliferation during thymus organogenesis |
| Q43175413 | Endoderm-specific deletion of Tbx1 reveals an FGF-independent role for Tbx1 in pharyngeal apparatus morphogenesis. |
| Q34187192 | Endothelial neuropilin disruption in mice causes DiGeorge syndrome-like malformations via mechanisms distinct to those caused by loss of Tbx1 |
| Q48238413 | Esophageal atresia and tracheo-esophageal fistula in a patient with Digeorge syndrome |
| Q28652450 | Evolutionary and developmental origins of the cardiac neural crest: building a divided outflow tract |
| Q82489492 | FISH investigation of 22q11.2 deletion in patients with immunodeficiency and/or cardiac abnormalities |
| Q64884964 | Failed Progenitor Specification Underlies the Cardiopharyngeal Phenotypes in a Zebrafish Model of 22q11.2 Deletion Syndrome. |
| Q28593240 | Fgf15 is required for proper morphogenesis of the mouse cardiac outflow tract |
| Q28513912 | Fgf8 expression in the Tbx1 domain causes skeletal abnormalities and modifies the aortic arch but not the outflow tract phenotype of Tbx1 mutants |
| Q35709763 | Fibroblast growth factor 9 (FGF9)-pituitary homeobox 2 (PITX2) pathway mediates transforming growth factor β (TGFβ) signaling to regulate cell proliferation in palatal mesenchyme during mouse palatogenesis. |
| Q37286661 | Focal adhesion kinase is required for neural crest cell morphogenesis during mouse cardiovascular development. |
| Q28591930 | Forkhead transcription factors, Foxc1 and Foxc2, are required for the morphogenesis of the cardiac outflow tract |
| Q33763901 | Frequency of 22q11.2 microdeletion in children with congenital heart defects in western poland |
| Q43116746 | Gain of function of Tbx1 affects pharyngeal and heart development in the mouse |
| Q28510321 | Gcm2 is required for the differentiation and survival of parathyroid precursor cells in the parathyroid/thymus primordia |
| Q33703791 | Gene expression in pediatric heart disease with emphasis on conotruncal defects |
| Q37999164 | Guiding differentiation of stem cells in vivo by tetracycline-controlled expression of key transcription factors. |
| Q36494895 | Hard to swallow: Developmental biological insights into pediatric dysphagia |
| Q33955251 | Histology of the pharyngeal constrictor muscle in 22q11.2 deletion syndrome and non-syndromic children with velopharyngeal insufficiency |
| Q36131140 | How insights from cardiovascular developmental biology have impacted the care of infants and children with congenital heart disease. |
| Q36379778 | Identification of a Tbx1/Tbx2/Tbx3 genetic pathway governing pharyngeal and arterial pole morphogenesis |
| Q41272218 | Identification of downstream genetic pathways of Tbx1 in the second heart field |
| Q64890460 | In the line-up: deleted genes associated with DiGeorge/22q11.2 deletion syndrome: are they all suspects? |
| Q28591405 | In vivo genetic ablation of the periotic mesoderm affects cell proliferation survival and differentiation in the cochlea |
| Q35071740 | Inactivation of Bmp4 from the Tbx1 expression domain causes abnormal pharyngeal arch artery and cardiac outflow tract remodeling. |
| Q33915737 | Inactivation of TGFbeta signaling in neural crest stem cells leads to multiple defects reminiscent of DiGeorge syndrome |
| Q52919619 | Increased nuchal translucency origins from abnormal lymphatic development and is independent of the presence of a cardiac defect. |
| Q61053714 | Insights into retinoic acid deficiency and the induction of craniofacial malformations and microcephaly in fetal alcohol spectrum disorder |
| Q39667693 | Investigation of TBX1 gene deletion in Iranian children with 22q11.2 deletion syndrome: correlation with conotruncal heart defects. |
| Q48275476 | Isolation and developmental expression analysis of Tbx22, the mouse homolog of the human X-linked cleft palate gene |
| Q34599920 | Jun is required in Isl1-expressing progenitor cells for cardiovascular development |
| Q64096984 | Left pulmonary artery in 22q11.2 deletion syndrome. Echocardiographic evaluation in patients without cardiac defects and role of Tbx1 in mice |
| Q58588198 | Loss of CXCL12/CXCR4 signalling impacts several aspects of cardiovascular development but does not exacerbate Tbx1 haploinsufficiency |
| Q28594025 | Loss of Gbx2 results in neural crest cell patterning and pharyngeal arch artery defects in the mouse embryo |
| Q28592234 | MOZ regulates the Tbx1 locus, and Moz mutation partially phenocopies DiGeorge syndrome |
| Q45338231 | Manipulation of endogenous regulatory elements and transgenic analyses of the Tbx1 gene. |
| Q28592838 | Mesodermal Tbx1 is required for patterning the proximal mandible in mice |
| Q28587491 | Mesodermal expression of Tbx1 is necessary and sufficient for pharyngeal arch and cardiac outflow tract development |
| Q57812897 | Microarray analysis detects differentially expressed genes in the pharyngeal region of mice lacking Tbx1 |
| Q57812915 | Microarray analysis of the Df1 mouse model of the 22q11 deletion syndrome |
| Q36072998 | Microdeletions and microduplications in patients with congenital heart disease and multiple congenital anomalies. |
| Q50856798 | Microdeletions/duplications involving TBX1 gene in fetuses with conotruncal heart defects which are negative for 22q11.2 deletion on fluorescence in-situ hybridization. |
| Q28081179 | Modeling a model: Mouse genetics, 22q11.2 Deletion Syndrome, and disorders of cortical circuit development |
| Q39159160 | Modeling human craniofacial disorders in Xenopus |
| Q35780325 | Modulation of noncanonical TGF-β signaling prevents cleft palate in Tgfbr2 mutant mice |
| Q91976560 | Molecular and cellular mechanisms of the organogenesis and development of the mammalian carotid body |
| Q39368791 | Morphological and molecular evolution of the ultimobranchial gland of nonmammalian vertebrates, with special reference to the chicken C cells. |
| Q37679075 | Nucleocytoplasmic functions of the PDZ-LIM protein family: new insights into organ development |
| Q30561780 | Numb family proteins are essential for cardiac morphogenesis and progenitor differentiation |
| Q52110116 | Overlapping deletions define novel embryonic lethal loci in the mouse t complex. |
| Q36178682 | Partitioning the heart: mechanisms of cardiac septation and valve development |
| Q53498123 | Pharyngeal arch deficiencies affect taste bud development in the circumvallate papilla with aberrant glossopharyngeal nerve formation. |
| Q30439057 | Pitx2-mediated cardiac outflow tract remodeling |
| Q58698903 | Polycomb Repressive Complex 2 is essential for development and maintenance of a functional TEC compartment |
| Q55066903 | Positional mapping of PRKD1, NRP1 and PRDM1 as novel candidate disease genes in truncus arteriosus. |
| Q28509491 | Prdm1 functions in the mesoderm of the second heart field, where it interacts genetically with Tbx1, during outflow tract morphogenesis in the mouse embryo |
| Q28589938 | Properties of branchiomeric and somite-derived muscle development in Tbx1 mutant embryos |
| Q37245183 | RNA binding proteins in the regulation of heart development. |
| Q36877617 | Rac1 Signaling Is Required for Anterior Second Heart Field Cellular Organization and Cardiac Outflow Tract Development. |
| Q36975915 | Rebalancing gene haploinsufficiency in vivo by targeting chromatin. |
| Q90163058 | Regulating Retinoic Acid Availability during Development and Regeneration: The Role of the CYP26 Enzymes |
| Q28607199 | Regulatory variant in FZD6 gene contributes to nonsyndromic cleft lip and palate in an African-American family |
| Q40165786 | Response gene to complement 32, a novel regulator for transforming growth factor-beta-induced smooth muscle differentiation of neural crest cells |
| Q40453177 | Retinoic acid down-regulates Tbx1 expression in vivo and in vitro. |
| Q36245113 | Revising the embryonic origin of thyroid C cells in mice and humans. |
| Q38490104 | Role of mesodermal FGF8 and FGF10 overlaps in the development of the arterial pole of the heart and pharyngeal arch arteries |
| Q41901850 | SDF1-CXCR4 signaling: A new player involved in DiGeorge/22q11-deletion syndrome. |
| Q81680192 | Secondary heart field contributes myocardium and smooth muscle to the arterial pole of the developing heart |
| Q42057283 | Secondary immunologic consequences in chromosome 22q11.2 deletion syndrome (DiGeorge syndrome/velocardiofacial syndrome). |
| Q35950127 | Single nucleotide polymorphism discovery in TBX1 in individuals with and without 22q11.2 deletion syndrome. |
| Q41910576 | Systematic survey of variants in TBX1 in non-syndromic tetralogy of Fallot identifies a novel 57 base pair deletion that reduces transcriptional activity but finds no evidence for association with common variants. |
| Q27316934 | TBX1 Represses Vegfr2 Gene Expression and Enhances the Cardiac Fate of VEGFR2+ Cells |
| Q90256023 | TBX1 is required for normal stria vascularis and semicircular canal development |
| Q35234113 | TBX1 protein interactions and microRNA-96-5p regulation controls cell proliferation during craniofacial and dental development: implications for 22q11.2 deletion syndrome |
| Q28588434 | Tbx1 controls cardiac neural crest cell migration during arch artery development by regulating Gbx2 expression in the pharyngeal ectoderm |
| Q30592681 | Tbx1 controls the morphogenesis of pharyngeal pouch epithelia through mesodermal Wnt11r and Fgf8a |
| Q28587462 | Tbx1 haploinsufficiency is linked to behavioral disorders in mice and humans: implications for 22q11 deletion syndrome |
| Q40616720 | Tbx1 is necessary for palatal elongation and elevation |
| Q35963888 | Tbx1 is regulated by tissue-specific forkhead proteins through a common Sonic hedgehog-responsive enhancer |
| Q36914162 | Tbx1 is required for second heart field proliferation in zebrafish |
| Q33788869 | Tbx1 modulates endodermal and mesodermal differentiation from mouse induced pluripotent stem cells |
| Q28591834 | Tbx1 regulates Vegfr3 and is required for lymphatic vessel development |
| Q28509508 | Tbx1 regulates population, proliferation and cell fate determination of otic epithelial cells |
| Q28511103 | Tbx1 regulates proliferation and differentiation of multipotent heart progenitors |
| Q50918494 | Tbx1 regulation of myogenic differentiation in the limb and cranial mesoderm. |
| Q37876851 | Tbx1, subpulmonary myocardium and conotruncal congenital heart defects. |
| Q30459881 | Tbx1: identification of a 22q11.2 gene as a risk factor for autism spectrum disorder in a mouse model |
| Q50737118 | The 22q11 deletion: DiGeorge and velocardiofacial syndromes and the role of TBX1. |
| Q37364947 | The cells that fill the bill: neural crest and the evolution of craniofacial development. |
| Q27024385 | The neural crest in cardiac congenital anomalies |
| Q38250192 | The neural crest: a versatile organ system. |
| Q28592076 | Tissue-specific roles of Tbx1 in the development of the outer, middle and inner ear, defective in 22q11DS patients |
| Q37290726 | Top-down or bottom-up: Contrasting perspectives on psychiatric diagnoses |
| Q37327760 | Transcription factor TBX1 overexpression induces downregulation of proteins involved in retinoic acid metabolism: a comparative proteomic analysis. |
| Q37955972 | Transcription factors in parathyroid development: lessons from hypoparathyroid disorders |
| Q37341674 | Understanding the role of Tbx1 as a candidate gene for 22q11.2 deletion syndrome |
| Q28209453 | Unraveling the genetic and developmental mysteries of 22q11 deletion syndrome |
| Q37899166 | Velopharyngeal dysfunction and 22q11.2 deletion syndrome: a longitudinal study of functional outcome and preoperative prognostic factors |
| Q51996534 | Visualization of outflow tract development in the absence of Tbx1 using an FgF10 enhancer trap transgene. |
| Q27027305 | Where hearing starts: the development of the mammalian cochlea |
| Q38366535 | Why increased nuchal translucency is associated with congenital heart disease: a systematic review on genetic mechanisms. |
| Q52056446 | XTbx1 is a transcriptional activator involved in head and pharyngeal arch development in Xenopus laevis. |
| Q53472656 | YPEL1 overexpression in early avian craniofacial mesenchyme causes mandibular dysmorphogenesis by up-regulating apoptosis. |
| Q34218341 | p53 Suppression partially rescues the mutant phenotype in mouse models of DiGeorge syndrome |
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